#Types of kidney disease

[megpricephotography]

Happy 11th Birthday, Flynnie!!

Birthday boy enjoyed a run around in the buttercup field & some birthday snacks!

[cbirt]

Scientists Develop Novel Machine Learning Models to Predict Comorbidities at an Early Stage of Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus (T2DM), a recognized risk factor for heart failure (HF) and cardiovascular illnesses such as chronic kidney disease (CKD), was diagnosed in an estimated 537 million people worldwide.

In order to manage CKD and HF in individuals with early stages of T2DM, a complete treatment strategy is preferred. Early and better detection of these disorders can improve results. But recent research indicates that T2DM patients’ CKD and HF are not properly recognized, which results in increased rates of disease progression and a worse prognosis.

Researchers at AstraZeneca and Ono Pharmaceuticals created a model that could predict the likelihood that individuals with T2DM who had no prior history of CKD would develop CKD/HF. This study is a major step toward early and better diagnosis of CKD and HF in patients with T2DM.

Continue Reading

[mimyclub-blogs]

How to Improve Kidney Function with diet.

Kidney failure occurs when the kidneys lose their ability to filter waste products and excess fluids from the blood effectively. Risk factors for kidney failure include: Diabetes: Uncontrolled diabetes over time can damage the blood vessels in the kidneys, leading to kidney failure. High blood pressure (hypertension): Hypertension can damage the blood vessels in the kidneys, impairing their…

[health-homeopathy]

Diabetes - Major Effects And Treatment

Did you know that diabetes mellitus can have detrimental effects on your body in the long run. Chronic diabetes is a condition where your blood sugar levels remain above normal levels for many years. Over a period of time thus can have negative effects on your body organs.

Following are the effects of diabetes mellitus on your body health and well-being: -

Blood vessels - They can become narrower. This leads to reduced blood supply to organs of the body.

Foot Ulcers

Itching

Chronic skin problems

Red foreskin

Gangrene

Kidney damage

Heart damage - Angina or even a Heart attack

Breathing difficulty

ED or erectile dysfunction

Recurring cold, cough and infections

Frozen shoulder

Hence it is necessary to start diabetes treatment to treat it.

Book appointment with the best homeopathy doctor for diabetes treatment at Dr. Mehta’s clinic in Mumbai, India.

[healthcare-gomedii]

Kidney Treatment in India

Kidney disease means that your kidneys have been damaged; that’s why they are not working properly. Many kidney conditions are "chronic" because kidney function deteriorates over time. At this point, you will need dialysis (artificial filtering) or a kidney transplant and the success rate of kidney treatment in India is cover 90% to 95%.

[reasonsforhope]

"The Biden administration on Thursday [August 15, 2024] released prices for the first 10 prescription drugs that were subject to landmark negotiations between drugmakers and Medicare, a milestone in a controversial process that aims to make costly medications more affordable for older Americans. 

The government estimates that the new negotiated prices for the medications will lead to around $6 billion in net savings for the Medicare program in 2026 alone when they officially go into effect, or 22% net savings overall. That is based on the estimated savings the prices would have produced if they were in effect in 2023, senior administration officials told reporters Wednesday.

The Biden administration also expects the new prices to save Medicare enrollees $1.5 billion in out-of-pocket costs in 2026 alone.

“For so many people, being able to afford these drugs will mean the difference between debilitating illness and living full lives,” Chiquita Brooks-LaSure, administrator for the Centers for Medicare & Medicaid Services, told reporters. “These negotiated prices. They’re not just about costs. They are about helping to make sure that your father, your grandfather or you can live longer, healthier.”

It comes one day before the second anniversary of President Joe Biden’s signature Inflation Reduction Act, which gave Medicare the power to directly hash out drug prices with manufacturers for the first time in the federal program’s nearly 60-year history.

Here are the negotiated prices for a 30-day supply of the 10 drugs, along with their list prices based on 2023 prescription fills, according to a Biden administration fact sheet Thursday.

What Medicare and beneficiaries pay for a drug is often much less than the list price, which is what a wholesaler, distributor or other direct purchaser paid a manufacturer for a medication before any discounts...

The administration unveiled the first set of medications selected for the price talks in August 2023, kicking off a nearly yearlong negotiation period that ended at the beginning of the month.

The final prices give drugmakers, which fiercely oppose the policy, a glimpse of how much revenue they could expect to lose over the next few years. It also sets a precedent for the additional rounds of Medicare drug price negotiations, which will kick off in 2025 and beyond. 

First 10 drugs subject to Medicare price negotiations

Eliquis, made by Bristol Myers Squibb, is used to prevent blood clotting to reduce the risk of stroke. 

Jardiance, made by Boehringer Ingelheim and Eli Lilly, is used to lower blood sugar for people with Type 2 diabetes. 

Xarelto, made by Johnson & Johnson, is used to prevent blood clotting, to reduce the risk of stroke.

Januvia, made by Merck, is used to lower blood sugar for people with Type 2 diabetes.

Farxiga, made by AstraZeneca, is used to treat Type 2 diabetes, heart failure and chronic kidney disease. 

Entresto, made by Novartis, is used to treat certain types of heart failure.

Enbrel, made by Amgen, is used to treat autoimmune diseases such as rheumatoid arthritis. 

Imbruvica, made by AbbVie and J&J, is used to treat different types of blood cancers. 

Stelara, made by Janssen, is used to treat autoimmune diseases such as Crohn’s disease.

Fiasp and NovoLog, insulins made by Novo Nordisk.

In a statement Thursday, Biden called the new negotiated prices a “historic milestone” made possible because of the Inflation Reduction Act. He specifically touted Vice President Kamala Harris’ tiebreaking vote for the law in the Senate in 2022.

Harris, the Democratic presidential nominee, said in a statement that she was proud to cast that deciding vote, adding there is more work to be done to lower health-care costs for Americans.

“Today’s announcement will be lifechanging for so many of our loved ones across the nation, and we are not stopping here,” Harris said in a statement Thursday, noting that additional prescription drugs will be selected for future rounds of negotiations."

-via CNBC, August 15, 2024

[indiacancersurgerysite]

The rate of spread can also depend on the specific type of kidney cancer. The most common type, called renal cell carcinoma (RCC), usually grows slowly and may not cause symptoms in the early stages.

[cripplecharacters]

Disabilities that You Should Consider Representing in Your Writing More… part 1

[large text: Disabilities that You Should Consider Representing in Your Writing More… part 1]

While all disabilities are underrepresented in basically all sorts of media, it’s hard to not notice the trend in what disabilities make up the majority of representation. It’s especially visible when having a blog like this, where we can see what disabilities writers even consider including in their writing, and which ones never come up.

One in four people are disabled. With eight billion people alive it means there’s a lot of disabled people, and a lot of reasons why they are disabled in the first place - but this diversity is rarely represented, even on this blog, and anyone who has been following for a while has probably noticed that fact.

To be blunt: there are disabilities other than “amputee” and “(otherwise invisibly disabled) mobility aid user”. Does that mean that it’s wrong to write either of those? Of course not, and we don’t want to imply that it is. Does it mean that either of these have a ton of good representation? Hell no. Does it mean that when you are deciding on what to give your character, you should think beyond (or along! people can be multiply disabled!) just those two? Absolutely. Disability is a spectrum with thousands of things in it - don’t limit yourself for no reason and embrace the diversity that’s built into it instead. 

This is, simply, a list of common disabilities. This is just a few of them, as this is part one of presumably many (or, at least three as of right now). By “common” we rather arbitrarily decided on “~1% or more” - so at least 1 in 100 people has the disabilities below, which is a lot. Featuring!: links that you should click, sources of the % that are mostly just medical reports and might be hard to read, and quick, very non-exhaustive explanations to give you a basic idea of what these are. 

Intellectual disability (about 1.5%) Intellectual disability is a condition we have written about at length before. It’s a developmental disability that affects things such as conceptualization, language, problem-solving, or social and self-care skills. ID can exist on its own or be a part of another condition, like Down Syndrome, Congenital Iodine Deficiency, or Fetal Alcohol Spectrum Disorders. This post covers a lot of basic information that you might need. We have an intellectual disability tag that you can look through!

Cancer survivors (5.4% in the US, about 0.55% worldwide) A cancer survivor is a pretty self-explanatory term. There is a lot of types of cancer and some of them are very common while others are very rare, which makes this a very diverse category. Cancers also have different survival rates. While not every survivor will have disabling symptoms, they definitely happen. Most of the long-term side effects are related to chemotherapy, radiation, and other medication, especially if they happened in children. They can include all sorts of organ damage, osteoporosis, cognitive problems, sensory disabilities, infertility, and increased rate of other cancers. Other effects include removal of the affected area, such as an eye, a spleen, breasts, or the thyroid gland, each of which will have different outcomes. Cancer, and cancer treatments, can also result in PTSD.

Diabetes (about 8.5%, ~95% of that are type 2) Diabetes is a group of endocrine conditions that cause hyperglycemia (high blood sugar) for various reasons depending on the type. The vast majority of people have type 2 diabetes, which can cause fatigue, poor healing, or feeling thirsty or hungry. A diabetic person will use insulin when needed to help manage their blood sugar levels. There are many complications related to diabetes, from neuropathy, to retinopathy, and chronic kidney disease, and there's a lot of disabilities that coexist with diabetes in general! You might want to check out the #how to write type 1 diabetes tag by @type1diabetesinfandom!

Disabling vision loss (about 7.5%) Blindness and low vision are a spectrum, ranging from total blindness (around 10% of legally blind people) to mild visual impairment. Blindness can be caused by countless things, but cataracts, refractive errors, and glaucoma are the most common. While cataracts cause the person to have a clouded pupil (not the whole eye!) blind eyes usually look average, with strabismus or nystagmus being exceptions to that fairly often (but not always). Trauma isn't a common cause of blindness, and accidents are overrepresented in fiction. A blind person can use a white cane, a guide dog or horse, or both. Assistive solutions are important here, such as Braille, screenreaders, or magnifying glasses. We have a blindness tag that you can look through, and you might want to check out @blindbeta and @mimzy-writing-online.

Psoriasis (about 2-4%) Psoriasis is a chronic skin condition with multiple subtypes; it can cause intense itching, pain, and general discomfort, and often carries social stigma. It’s an autoimmune and non-contagious disability that affects the skin cells, resulting in raised patches of flaky skin covered with scales. It often (30%) leads to a related condition, psoriatic arthritis, which causes joint pain, tenderness, and fatigue, among other things.

Stroke survivors (0.5-1%) A stroke survivor is a person who has survived any kind of stroke (ischemic, hemorrhagic, etc.). While the specific symptoms often depend on the exact location on where the stroke happened, signs such as hemiplegia, slurred speech, vision problems, and cognitive changes are common in most survivors to some degree. When someone has a stroke as a baby, or before they are born, it can result in cerebral palsy, epilepsy, and other disabilities. We have a brain injury tag that you can look through!

Noonan Syndrome (about 0.1-1% - mild is 1%, severe 0.1%) Noonan Syndrome is a disability that is almost never mentioned in any context, but certainly not around the topic of writing disabled characters. It’s a congenital condition that can cause cardiomyopathy, chronic joint pain, hypermobility, short stature, facial differences such as ptosis, autism, and various lymphatic problems among other things. Some people with Noonan Syndrome might use mobility aids to help with their joint pain.

Hyperthyroidism (about 1.2%) Hyperthyroidism is a condition of the endocrine system caused by hormone overproduction that affects metabolism. It often results in irritability, weight loss, heat intolerance, tremors, mood swings, or insomnia. Undertreated hyperthyroidism has a rare, but extremely dangerous side effect associated with it called a thyroid storm, which can be fatal if untreated.

Hypothyroidism (>5%) Hypothyroidism is an endocrine condition just as hyperthyroidism is, and it causes somewhat opposite symptoms. Due to not producing enough thyroid hormones, it often causes fatigue, depression, hair loss, weight gain, and a frequent feeling of being cold. It’s often comorbid with other autoimmune disabilities, e.g. vitiligo, chronic autoimmune gastritis, and rheumatoid arthritis. Extreme hypothyroidism can also be potentially fatal because of a condition known as Myxedema coma (or “crisis”), which is also rare.

Deafblindness (about 0.2-2%) Being DeafBlind is often considered to be an extremely rare disability, but that’s not really the case. DeafBlindness on its own isn’t a diagnosis - it can be caused by a wide range of things, with CHARGE syndrome (congenital), Usher syndrome (born deaf, becomes blind later in life), congenital rubella, and age-related deafness and blindness being some of the most common reasons. DeafBlindness is a wide spectrum, the vast majority of DeafBlind people aren’t fully blind and deaf, and they can use various ways of communication. Some of these could be sign language (tactile or not), protactile, the deafblind manual, oral speech (aided by hearing aids or not), the Lorm alphabet, and more. You can learn more about assistive devices here! Despite what various media like to tell you, being DeafBlind isn’t a death sentence, and the DeafBlind community and culture are alive and thriving - especially since the start of the protactile movement. We have a DeafBlindness tag that you can look through!

It’s probably worth mentioning that we have received little to no asks in general for almost all the disabilities above, and it’s certainly not due to what mods answer for. Our best guess is that writers don’t realize how many options they have and just end up going for the same things over and over.

Only representing “cool” disabilities that are “not too much while having a particular look/aura/drama associated” isn’t what you should aim for. Disabled people just exist, and all of us deserve to be represented, including those whose disabilities aren’t your typical “cool design” or “character inspo”. Sometimes we are just regular people, with disabilities that are “boring” or “too much”, and don’t make for useful plot points.

mod Sasza (with huge thank yous to mod Sparrow, Rot, and Virus for their contributions with research and data!)

[ceyhanmedya]

Open Nephrectomy 2023

New Post has been published on https://bankakredin.com/open-nephrectomy-2023/

Open Nephrectomy 2023

Like every organ, the kidneys are of great importance for human health. The kidney, which is located on both sides of the abdominal cavity and resembles a bean in shape, works like a filter in the human body and ensures that harmful and waste materials are removed from the body and the blood is cleaned. Thanks to this article, you can have information about the open nephrectomy operation used in the treatment of kidney diseases.

What is nephrectomy?

A healthy functioning of one of the kidneys in the human body is sufficient for the continuation of vital functions. However, in some cases, malfunctions in the kidney, which is so vital for human health, can cause an  increase  in urea and creatinine  in the body, resulting in kidney failure , damage to kidney tissue, and the formation of cancer in the kidney. In this case, it may be necessary to remove the sick kidney from the body by operation. The operation to remove the kidney from the body is called nephrectomy.

What is Open Nephrectomy?

Nephrectomy, which is the process of removing the kidney from the body, can be performed by open surgery or laparoscopic surgery. If the operation is performed with the open surgery method, this procedure is called open nephrectomy. In some cases, specialists may decide that it is not appropriate for the patient to remain under anesthesia for a long time. In this case, the laparoscopic (closed) nephrectomy method may be preferred as an alternative to the open nephrectomy method. Today, although the post-operative period is more comfortable, patients and specialists prefer the laparoscopic nephrectomy method, open nephrectomy is still one of the most effective methods used in the treatment of kidney diseases in cases where the laparoscopic nephrectomy method is not suitable.

In cases of polycystic kidney disease,

In the removal of tumor in kidney cancers  ,

In cases where the donor and the recipient must be together in the case of chronic kidney failure, which is seen as a result of long-term tissue damage in the kidney tissue,

In disorders of the pancreas.

There is the possibility of treatment with open nephrectomy method in many diseases from kidney cancer to kidney injuries, polycystic kidney diseases and pancreatic problems.

Nephrectomy can be grouped into two classes as partial nephrectomy and radical nephrectomy.

In some cases, removing the tumor tissue is sufficient to treat the disease. This procedure is known as partial nephrectomy. In some cases, since it is not possible to leave intact kidney tissue, the entire kidney must be removed during the operation. This procedure is called radical nephrectomy. If both kidneys are damaged, both kidneys may need to be removed from the body, but in this case, a kidney transplant is needed because it is not possible for the patient to live without their kidneys. Open nephrectomy operations are operations where the recipient and donor are together. Before this operation, some analyzes are performed on the receiver and the transmitter. If, as a result of these analyzes, the results of the recipient and the donor are compatible, the operation is started. The kidney from the donor is placed in the recipient. During this procedure, the healthy kidney is placed on the right or left side of the recipient. The process of taking a healthy kidney from the donor and attaching it to the recipient is known as donor nephrectomy.

In cases where kidney transplantation is required, the patient’s own kidney is not removed if the diseased kidney is not at risk of cancer or if there is no infection.

Open Partial Nephrectomy

In kidney cancer patients, nephrectomy operation, in which tumor tissue is removed and intact kidney tissue is left, is known as partial (partial) nephrectomy. During the partial nephrectomy procedure, the surgeon reaches the tumor through the opened incisions. For this reason, open nephrectomy method is preferred in partial nephrectomy operations. Open partial nephrectomy may be preferred in the following cases:

kidney cancers,

Infections in the kidney that cannot be treated with drug therapy,

Kidney failure,

The possibility of deterioration in the function of the other kidney,

Injuries to the kidney,

Conditions in which the blood supply of the kidney decreases as a result of occlusion in the vessels leading to the kidney,

Hypertension as a result of problems in the blood supply of the kidneys  ,

Congenital kidney anomalies.

During open partial nephrectomy, after an incision is made in the abdominal wall, the vessels leading to and exiting the kidney are clamped to prevent bleeding in the kidney. After the diseased tissue is removed, the clamp is removed and blood flow is restored to the kidney.

The duration of the open partial nephrectomy operation varies according to the size of the cancerous or impaired tissue. The procedure can be performed within 1-2 hours on average. However, as with any open surgery, there are some complications that may occur during open nephrectomy. Some of these complications are as follows:

During open partial nephrectomy, bleeding may occur that requires urgent blood supply.

The healing process can be long and accordingly  urinary incontinence  problems may occur.

Since the operation is performed in the form of open surgery, pain may be felt in the operation area for a few weeks after open partial nephrectomy.

Since open nephrectomy is performed under general anesthesia, allergic reactions to anesthesia may occur in some cases, but this is very rare because the necessary analyzes are performed by a specialist team before anesthesia.

After open partial nephrectomy surgery, patients are discharged within an average of 1 week. In the post-hospital period, patients are asked to pay attention to some points. In this process, the patient;

Should consume plenty of fluids,

Avoid doing heavy exercises until the surgical wounds are fully healed,

He should not neglect to go to his check-ups.

Open Radical Nephrectomy

Radical nephrectomy is a frequently used treatment method in kidney cancer treatments. In some cases, it is not possible to remove a part of the kidney, especially in the later stages of kidney cancer. In this case, the kidney and the fat tissue under the kidney must be completely removed. The process of removing the kidney completely is called radical nephrectomy. If the other kidney is healthy, one kidney will also perform the task of the kidney that was taken. However, in cases where there is a tumor in both kidneys and both kidneys need to be removed, kidney transplantation is necessary. In this case, open nephrectomy is performed with an operation where the donor and the recipient are together. If the kidney with tumor is not intervened, the tumor continues to grow and begins to damage other organs. This leads to many different health problems.

Radical nephrectomy can be performed as laparoscopic or open nephrectomy. In some cases, the operation is started with the closed surgery method and open nephrectomy can be started during the procedure.

General anesthesia is used during the open radical nephrectomy procedure. An incision is made under the ribs and the kidney is reached.

As with other surgeries, open radical nephrectomy has some risks. These risks can be listed as follows:

In patients who underwent radical nephrectomy with open surgery, pain after the operation is a common side effect.

In some cases, although rare, bleeding may occur during or after the operation.

Infection of the surgical wound is one of the rare side effects. In order to prevent this situation from happening, it is important to have dressing as the doctor says.

One of the rare conditions is intestinal obstruction.

After the partial nephrectomy procedure, as well as after the open radical nephrectomy, the patient will be sick for a while;

Should consume plenty of fluids,

Avoid lifting heavy loads

Intense exercises should be avoided.

Kidneys take on the task of filtering in the body and ensure that harmful substances and wastes are removed from the body. In case of any chronic or acute problem in the kidneys, harmful substances accumulate in the body and this adversely affects human health. Thanks to the developments in the medical world and the doctors who are experts in the field, it is possible to treat the diseases that occur in the kidneys. Do not forget to have the necessary controls for your health before it is too late.

nephrectomy, why are nephrectomy performed, what are the complications of nephrectomy, what are the side effects of a partial nephrectomy, what are the types of nephrectomy, what are the indications for nephrectomy, how dangerous is a nephrectomy, how painful is a nephrectomy, what is an open nephrectomy, can you have a partial nephrectomy, can nephrectomy cause erectile dysfunction, what is the code for an open partial nephrectomy, can nephrectomy cause diabetes, can nephrectomy cause ckd, can nephrectomy cause chronic kidney disease, can nephrectomy causes kidney failure, can nephrectomy cause renal failure, can i drink alcohol after a nephrectomy, can a nephrectomy be done laparoscopically, what can i expect after a partial nephrectomy,

[bamsara]

I just read chapter 20 and if I remember correctly Narinder said something about Joon's lungs filling with fluid? I did some research and I found out that the reason that lungs do that is either from pneumonia, traveling at high altitude, and types of heart and kidney disease.

I'm a little worried.

(If Narinder didn't say anything about this and I'm going crazy again or this ask made you uncomfortable, please ignore and delete it and I'm sorry.)

Nope! You're right on this one: Joon has the early stages of pneumonia, and will get worse as the story continues unless something particular is done. While nausea and committing aren't common effects of it, they can still be an indicator, but Joon is gonna to be suffering that + the symptoms that will start to develop. Double whammy

[reality-detective]

“I gathered all vaccine ingredients into a list and contacted Poison Control. After intros and such, and asking to speak with someone tenured and knowledgeable, this is the gist of that conversation.

Me: My question to you is how are these ingredients categorized? As benign or poison? (I ran a few ingredients, formaldehyde, Tween 80, mercury, aluminum, phenoxyethanol, potassium phosphate, sodium phosphate, sorbitol, etc.)

He: Well, that's quite a list... But I'd have to easily say that they're all toxic to humans... Used in fertilizers... Pesticides... To stop the heart... To preserve a dead body... They're registered with us in different categories, but pretty much poisons. Why?

Me: If I were deliberately to feed or inject my child with these ingredients often, as a schedule, obviously I'd put my daughter in harm's way... But what would legally happen to me?

He: Odd question... But you'd likely be charged with criminal negligence... perhaps with intent to kill... and of course child abuse... Your child would be taken away from you... Do you know of someone's who's doing this to their child? This is criminal...

Me: An industry... These are the ingredients used in vaccines... With binding agents to make sure the body won't flush these out... To keep the antibody levels up indefinitely...

The man was beside himself. He asked if I would email him all this information. He wanted to share it with his adult kids who are parents. He was horrified and felt awful he didn't know... his kids are vaccinated and they have health issues...”

~  By  Iris Figueroa

Here are just SOME vaccine ingredients present in routine vaccines:

◾️Formaldehyde/Formalin - Highly toxic systematic poison and carcinogen.

◾️Betapropiolactone - Toxic chemical and carcinogen. May cause death/permanant injury after very short exposure to small quantities. Corrosive chemical.

◾️Hexadecyltrimethylammonium bromide - May cause damage to the liver, cardiovascular system, and central nervous system. May cause reproductive effects and birth defects.

◾️Aluminum hydroxide, aluminum phosphate, and aluminum salts - Neurotoxin. Carries risk for long term brain inflammation/swelling, neurological disorders, autoimmune disease, Alzheimer's, dementia, and autism. It penetrates the brain where it persists indefinitely.

◾️Thimerosal (mercury) - Neurotoxin. Induces cellular damage, reduces oxidation-reduction activity, cellular degeneration, and cell death. Linked to neurological disorders, Alzheimer's, dementia, and autism.

◾️Polysorbate 80 & 20 - Trespasses the Blood-Brain Barrier and carries with it aluminum, thimerosal, and viruses; allowing it to enter the brain.

◾️Glutaraldehyde - Toxic chemical used as a disinfectant for heat sensitive medical equipment.

◾️Fetal Bovine Serum - Harvested from bovine (cow) fetuses taken from pregnant cows before slaughter.

◾️Human Diploid Fibroblast Cells - aborted fetal cells. Foreign DNA has the ability to interact with our own.

◾️African Green Monkey Kidney Cells - Can carry the SV-40 cancer-causing virus that has already tainted about 30 million Americans.

◾️Acetone - Can cause kidney, liver, and nerve damage.

◾️E.Coli - Yes, you read that right.

◾️DNA from porcine (pig) Circovirus type-1

◾️Human embryonic lung cell cultures (from aborted fetuses)

You can view all of these ingredients on the CDCs website: 👇

You are always welcome to do your own research, in fact I encourage you to do so. 🤔

[icarusredwings]

This has been on my mind for NO Fucking reason so to make it shut up, lets talk about it.

"Why doesn't Wade just do chemotherapy?"

In this essay, I will explain the answer to that question, looking at Germ cancer cells and testicular cancer rates to decide-

Can Wade have biological kids?

Let's start with the basic facts.

What a germ cell tumor?

A germ cell tumor is a mass made of reproductive cells, also called germ cells. “Germ” is short for “germinate,” which means to mature. For men and people assigned male at birth (AMAB), germ cells mature into sperm. Related, germ cell tumors most often form where eggs get made (ovaries) and where sperm gets made (testicles).

[ https://my.clevelandclinic.org/health/diseases/23505-germ-cell-tumor]

Testicular cancer.

Most testicular cancers start in cells known as germ cells and are called germ cell tumours. Germ cells in men produce sperm. Testicular germ cell tumours can develop from germ cell neoplasia in situ (GCNIS). GCNIS means that there are abnormal cells in the testicle.

[https://www.cancerresearchuk.org/about-cancer/testicular-cancer/types#:~:text=Most%20testicular%20cancers%20start%20in,abnormal%20cells%20in%20the%20testicle.]

More than 90% of testicular cancer start in the germ cells, which are cells in the testicles and develop into sperm. This type of cancer is known as testicular germ cell cancer. Testicular germ cell cancer can be classified as either seminomas or nonseminomas, which may be identified by microscopy.

[https://www.cancer.gov/ccg/research/genome-sequencing/tcga/studied-cancers/testicular-germ-cell-study ]

Treatments.

At the moment there is not a lot of options, the most common are:

Chemotherapy

Radiation

Surgery

Chemotherapy.

Chemotherapy works by stopping or slowing the growth of cancer cells, which grow and divide quickly. Because of his healing factor, this would probably not work and if anything cause Wade more illness seeing as Chemo causes

Fatigue

Hair loss

Easy bruising and bleeding

Infection

Anemia (low red blood cell counts)

Nausea and vomiting

Appetite changes

Constipation

Diarrhea

Mouth, tongue, and throat problems such as sores and pain with swallowing

Peripheral neuropathy or other nerve problems, such as numbness, tingling, and pain

Skin and nail changes such as dry skin and color change

Urine and bladder changes and kidney problems

Weight changes

Chemo brain, which can affect concentration and focus (serve mind fog)

Mood changes

Changes in libido and sexual function

And last but not least Fertility problems

[https://www.cancer.org/cancer/managing-cancer/treatment-types/chemotherapy/chemotherapy-side-effects.html ]

Radiation.

At high doses, radiation therapy kills cancer cells or slows their growth by damaging their DNA. Cancer cells whose DNA is damaged beyond repair stop dividing or die. When the damaged cells die, they are broken down and removed by the body. In theory this would work a little bit, for about 12 minutes and then he immediately would have all of those dead cells back because while the radiology killed one spot, cancer spreads. Quickly. With his healing factor its MUCH quicker too. All that pain for nothing.

Fatigue

Hair loss

Memory or concentration problems

Throat problems, such as trouble swallowing

Cough

Shortness of breath

Taste changes

Skin changes (such as burning and peeling)

Less active thyroid gland

Sexual problems

Fertility problems

Urinary and bladder problems

[https://www.cancer.gov/about-cancer/treatment/types/radiation-therapy]

Surgery.

I dont even need any sources for this. We saw what happened to his legs when ripped off. They just grew back. And if removing cancer cells makes newer cancer cells? That's useless.

Summary.

Wades entire body is cancerous. Yes. His ENTIRE body. Every arm, toe, and fingernail on this man is cancerous. His healing factor is literally just having rapid cancer growth (amongst other things)

Chemotherapy and radiation will not work on him. Chemotherapy works by killing cancerous cells in order to grow healtheir ones. Except Wade can only produce cancerous cells. Yes, while they are new and much more likely in the very early stages, it's still cancerous.

This being said, there is no cure or treatment for Wades Cancer (that we know of at this time) Its quite physically the only thing keeping him with super hero powers yet still remains even after his powers are taken.

Hate to say it.

I hate to say it but statistically removing older, more advanced cells to replace with newer, less progressive cells (aka removing or ripping off his limbs/ parts of his body so they can grow back as new and fresh) is probably the best 'treatment' Wade has right now. Radiology would work the same, right?

Yes, but A. Not as B. Too many side effects that he he'll have to deal with MORE making him even more crazy and sick. Why would he do that when he can just tease Logan into slicing a hurt leg off and go from there?

Will the treatment help him be fertile?

Realistically, without his powers, he probably would be dead in a week, perhaps less due to just HOW much cancer this man truly has.

Chemo would also make it worse. So much worse, in fact. Both pain wise and his chances at ever biologically having a child.

Result(s) Before the cancer was diagnosed, (66%) 79/120 couples who attempted to conceive succeeded within 1 year. After (Cancer) treatment, (43%) 38/88 couples conceived within 1 year.

[https://www.fertstert.org/article/S0015-0282(03)00335-2/fulltext]

Testical Germ Cell Tumors are associated with semen abnormalities before orchiectomy. This review shows an increase in abnormal semen parameters among men with TGCT even outside the treatment effects of orchiectomy, radiation, or chemotherapy.

[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270136/ ]

The way that TGCT affects the sperm is that it's very common for not only lower sperm count (obviously, it's hard to produce when you're fighting an entire body illness) but also changes the shape of the sperm which makes it very difficult to reach the egg. Sperm with crooked tails, double tails, double heads, or even broken sperm have a very hard time reaching the egg (think of it like natural selection) and die off before they get anywhere. If you already have low countage and most of them can't make it?

Well that's much lower chances of fertility.

In the comics.

In the comics, Wade has a daughter named Eleanor Camacho in which he was unaware of because her mother saw his face and ran away in terror. The entire thing is that her mother thought she was going to die and decided fuck it, if im gonna die Im gonna die happy so decided to spend these last moments with wade (who she literally just met- if that aint weird in itself idk what is).

She only ever found him to demand child support, and he refused to believe such a beautiful child could he his given his stance of insecurity and well- Just utter shock anyway, I think. He is right. Eleanor is gorgeous as a baby and as an adult.

(There's actually a whole comic where he's trying to fight death so his daughter doesn't die before him because he "couldn't bear the thought of living without her" so they activate a bomb "with the power of a black hole" and comit death together. It's very sweet)

TLDR

In conclusion.

Yes, Wade can have children, but he has a better chance at being successful if he removes his lower half and regrows it so that its *less* cancerous than before cells, therefore hes more likely to have normal shaped sperm and probably more of it during the process.

No, chemotherapy, radiation, and surgery would not be effective. Unfortunately, the most effective thing for him is ripping his limbs off sometimes.

"Forest- why the fuck did you write this?"

You know... I really don't know. I wanted to become a bio geneticist, and here I am. Writing about some bald guys' balls on the Internet. Siiigghh... anyway. Use this. however you want, I don't even care at this point.

[healthcare-gomedii]

Success Rate of Kidney Treatment in India

Kidney disease means there is damage to your kidneys; hence aren’t working properly. Many kidney conditions are “chronic” because the kidney function worsens over time. The success rate of kidney treatment in India is between 90%-95%.

[olowan-waphiya]

of fucking course.....they fucking coated paper straws with pfas......its a fucking nightmare

--

Long-lasting 'forever chemicals', which can cause damaging health issues, found in 18/20 brands of paper straws

In the first analysis of its kind in Europe, and only the second in the world, Belgian researchers tested 39 brands of straws for the group of synthetic chemicals known as poly- and perfluoroalkyl substances (PFAS).

PFAS were found in the majority of the straws tested and were most common in those made from paper and bamboo, the study, published in the peer-reviewed journal Food Additives and Contaminants, found.

PFAS are used to make everyday products, from outdoor clothing to non-stick pans, resistant to water, heat and stains. They are, however, potentially harmful to people, wildlife and the environment.

They break down very slowly over time and can persist over thousands of years in the environment, a property that has led to them being known as "forever chemicals."

They have been associated with a number of health problems, including lower response to vaccines, lower birth weight, thyroid disease, increased cholesterol levels, liver damage, kidney cancer and testicular cancer.

"Straws made from plant-based materials, such as paper and bamboo, are often advertised as being more sustainable and eco-friendly than those made from plastic," says researcher Dr Thimo Groffen, an environmental scientist at the University of Antwerp, who is involved in this study.

"However, the presence of PFAS in these straws means that's not necessarily true."

A growing number of countries, including the UK and Belgium, have banned sale of single-use plastic products, including drinking straws, and plant-based versions have become popular alternatives.

A recent study found PFAS in plant-based drinking straws in the US. Dr Groffen and colleagues wanted to find out if the same was true of those on sale in Belgium.

To explore this further, the research team purchased 39 different brands of drinking straw made from five materials -- paper, bamboo, glass, stainless steel and plastic.

The straws, which were mainly obtained from shops, supermarkets and fast-food restaurants, then underwent two rounds of testing for PFAS.

The majority of the brands (27/39, 69%) contained PFAS, with 18 different PFAS detected in total.

The paper straws were most likely to contain PFAS, with the chemicals detected in 18/20 (90%) of the brands tested. PFAS were also detected in 4/5 (80%) brands of bamboo straw, 3/4 (75%) of the plastic straw brands and 2/5 (40%) brands of glass straw. They were not detected in any of the five types of steel straw tested.

The most commonly found PFAS, perfluorooctanoic acid (PFOA), has been banned globally since 2020.

Also detected were trifluoroacetic acid (TFA) and trifluoromethanesulfonic acid (TFMS), "ultra-short chain" PFAS which are highly water soluble and so might leach out of straws into drinks.

The PFAS concentrations were low and, bearing in mind that most people tend to only use straws occasionally, pose a limited risk to human health. However, PFAS can remain in the body for many years and concentrations can build up over time.

"Small amounts of PFAS, while not harmful in themselves, can add to the chemical load already present in the body," says Dr Groffen.

It isn't known whether the PFAS were added to the straws by the manufacturers for waterproofing or whether were the result of contamination. Potential sources of contamination include the soil the plant-based materials were grown in and the water used in the manufacturing process.

However, the presence of the chemicals in almost every brand of paper straw means it is likely that it was, in some cases, being used as a water-repellent coating, say the researchers.

The study's other limitations include not looking at whether the PFAS would leach out of the straws into liquids.

Dr Groffen concludes: "The presence of PFAS in paper and bamboo straws shows they are not necessarily biodegradable.

"We did not detect any PFAS in stainless steel straws, so I would advise consumers to use this type of straw -- or just avoid using straws at all."