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jcmarchi · 10 months

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AI May Spare Breast Cancer Patients Unnecessary Treatments - Technology Org

New Post has been published on https://thedigitalinsider.com/ai-may-spare-breast-cancer-patients-unnecessary-treatments-technology-org/

AI May Spare Breast Cancer Patients Unnecessary Treatments - Technology Org

New AI tool is the first to combine cancerous and non-cancerous cell patterns to predict outcomes in invasive breast cancer.

A new artificial intelligence (AI) tool may make it possible to spare breast cancer patients unnecessary chemotherapy treatments by using a more precise method of predicting their outcomes, reports a new Northwestern Medicine study.

This is the first study to use AI for comprehensive evaluation of both the cancerous and non-cancerous elements of invasive breast cancer. Image credit: U.S. Air Force photo by Senior Airman Tiffany Trojca via holloman.af.mil, Public Domain

Artificial intelligence evaluations of patient tissues were better at predicting the future course of a patient’s disease than evaluations performed by expert pathologists.

The AI tool was able to identify breast cancer patients who are currently classified as high or intermediate risk but who become long-term survivors. That means the duration or intensity of their chemotherapy could be reduced. This is important since chemotherapy is associated with unpleasant and harmful side effects such as nausea, or more rarely, damage to the heart.

Currently, pathologists evaluate cancerous cells in a patient’s tissue to determine treatment. But patterns of non-cancerous cells are very important in predicting outcomes.

This is the first study to use AI for comprehensive evaluation of both the cancerous and non-cancerous elements of invasive breast cancer.

“Our study demonstrates the importance of non-cancer components in determining a patient’s outcome,” said corresponding study author Lee Cooper, associate professor of pathology at Northwestern University Feinberg School of Medicine. “The importance of these elements was known from biological studies, but this knowledge has not been effectively translated to clinical use.”

The study was published in Nature Medicine.

In 2023, about 300,000 U.S. women will receive a diagnosis of invasive breast cancer. About one in eight U.S. women will receive a breast cancer diagnosis in their lifetime.

During diagnosis, a pathologist reviews the cancerous tissue to determine how abnormal the tissue appears. This process, known as grading, focuses on the appearance of cancer cells and has remained largely unchanged for decades. The grade, determined by the pathologist, is used to help determine what treatment a patient will receive.

Many studies of breast cancer biology have shown that the non-cancerous cells, including cells from the immune system and cells that provide form and structure for the tissue, can play an important role in sustaining or inhibiting cancer growth.

Cooper and colleagues built an artificial intelligence model to evaluate breast cancer tissue from digital images that measures the appearance of both cancerous and non-cancerous cells, as well as interactions between them.

“These patterns are challenging for a pathologist to evaluate as they can be difficult for the human eye to categorize reliably,” said Cooper, also a member of the Robert H. Lurie Comprehensive Cancer Center of Northwestern University.

“The AI model measures these patterns and presents information to the pathologist in a way that makes the AI decision-making process clear to the pathologist.”

The AI system analyzes 26 different properties of a patient’s breast tissue to generate an overall prognostic score. The system also generates individual scores for the cancer, immune and stromal cells to explain the overall score to the pathologist. For example, in some patients, a favorable prognosis score may be due to properties of their immune cells, where for others it may be due to properties of their cancer cells. This information could be used by a patient’s care team in creating an individualized treatment plan.

Adoption of the new model could provide patients diagnosed with breast cancers with a more accurate estimate of the risk associated with their disease, empowering them to make informed decisions about their clinical care, Cooper said.

Additionally, this model may help in assessing therapeutic response, allowing treatment to be escalated or de-escalated depending on how the microscopic appearance of the tissue changes over time. For example, the tool may be able to recognize the effectiveness of a patient’s immune system in targeting the cancer during chemotherapy, which could be used to reduce the duration or intensity of chemotherapy.

“We also hope that this model could reduce disparities for patients who are diagnosed in community settings,” Cooper said. “These patients may not have access to a pathologist who specializes in breast cancer, and our AI model could help a generalist pathologist when evaluating breast cancers.”

The study was conducted in collaboration with the American Cancer Society (ACS) which created a unique dataset of breast cancer patients through their Cancer Prevention Studies. This dataset has representation of patients from over 423 U.S. counties, many who received a diagnosis or care at community medical centers.

This is important, because most studies typically use data from large academic medical centers which represent only a portion of the U.S. population. In this collaboration, Northwestern developed the AI software while scientists at the ACS and National Cancer Institute provided expertise on breast cancer epidemiology and clinical outcomes.

To train the AI model, scientists required hundreds of thousands of human-generated annotations of cells and tissue structures within digital images of patient tissues. To achieve this, they created an international network of medical students and pathologists across several continents. These volunteers provided this data through a website over the course of several years to make it possible for the AI model to reliably interpret images of breast cancer tissue.

Next the scientists will evaluate this model prospectively to validate it for clinical use. This coincides with the transition to using digital images for diagnosis at Northwestern Medicine, which will happen over the next three years.

The scientists also are working to develop models for more specific types of breast cancers like triple-negative or HER2-positive. Invasive breast cancer encompasses several different categories, and the important tissue patterns may vary across these categories.

“This will improve our ability to predict outcomes and will provide further insights into the biology of breast cancers,” Cooper said.

Source: Northwestern University

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abdallahs-posts · 2 months

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We, the residents of Gaza, are living a daily nightmare of bombings, killings, random shelling, and starvation. The continuous bombardment has brought destruction to our homes, forcing us to live among the rubble and in tents. Water and food have become scarce, and we have to walk long distances every day to get water, exposing ourselves to the risk of disease from severe pollution or death from random shelling. Our tents have no air conditioning and are extremely hot in this summer weather. Everywhere around us, the Israeli occupation forces continue their bombing and aggression.

With each new day, our suffering increases, but our hopes for a better tomorrow remain alive. That is why I have created a donation link to help us escape this miserable life. With your help, we can register all my family members and leave together without worrying about leaving anyone behind in Gaza. We kindly ask you to share this fundraising campaign.

I believe that every donation, no matter how small, can make a difference and help alleviate my family’s suffering by giving them a new chance at life and restoring the hopes and dreams we were forced to abandon. I would be sincerely grateful for any kind of support, whether through donations or simply by sharing the fundraising campaign link with your friends and family and as widely as possible within your social networks.

https://www.gofundme.com/f/help-abdallah-khader-and-his-family-survive-the-gaza-war?utm_source=copy_link&utm_medium=customer&utm_campaign=man_sharesheet_ft&attribution_id=sl:2c648430-dd5f-4088-91ff-90aa94d79154

We are all deeply grateful and honored and will never forget your kindness during our difficult times. Thank you.

#free palestine #palestinian genocide #save palestine #i stand with palestine #gaza #free gaza #gaza strip #all eyes on rafah #all eyes on gaza #watermelon #free palestine 🇵🇸

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k-hotchoisan · 6 months

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the scentist

Your neighbour—Choi San—is such a gentleman on top of being a complete hunk and smelling so fuckin good. Especially so when he offers his hoodie when he sees you being drenched. Well, nothing could come out of such a simple gesture of kindness, right?

Genres/Warnings: perverted & obsessed scentist!San, Olfactophilia (sexual arousal from scent), masturbation on clothing, oral (F receiving), unprotected sex, cumming untouched, armlock (light) breeding, pussy drunk San💙

💙 @san-network 💜

Taglist: @bro-atz @diamond-3 @mcarebearsstuff @choisansplushie @voicesinmyhead-rc @pre1ttyies @hwallazia @songmingisthighs @yeosangiess @interweab @mylovelymito @softwsan @yourlocaljonghoe @itza-meee @ywtf @jeon-ify

A/N: WE BEEN KNEW THAT I’D LEAVE MY FAVOURITE MAN FOR THE LAST!! 😮‍💨 don’t be sad that this event is ending ok,, we got more to cum come 🥰 thank u for giving my fics so much love as always!!

🩷back to staying perverted

Lavender. Sweet pea. Azalea. Gardenia.

The scents of the florals fill his lab, something he’s so used to already. As the concoction bubbles, he walks over to the other flowers potted along the shelf, pressing the petals against his nose, taking in their smell before he pulls away. He pulls off his goggles, walking over to his desk, staring at the standing whiteboard, filled to the corners with flower names, chemical compounds, and other miscellaneous details. Even though he’s doing fine, he feels that something is missing. Choi San feels stale and stuck.

The rain is pattering down heavily against the pavement, he stares at the raindrops hitting the leaves of his plants. San often gets compliments on how beautiful his plants are, and how natural he is at gardening. San would don his signature smile and he would thank them for the compliment. Sometimes, his neighbours would come by to ask for gardening advice and San would gladly entertain them. This evening was no different. Another one of his neigbours who was growing greens had wanted to express appreciation by buying San his favorite fertilizers. Stacking them neatly in his cabinet, San then decides to head down to the reception to receive his parcel.

Fuck. The downpour was so sudden. It totally caught you off guard, and you were drenched before you realised it. You make it to the entrance of your apartment complex, shivering slightly from the air conditioning. You shake off the excess water off your arms, and when you look up, your heartbeat quickens—your apartment complex crush is standing at his letterbox, filtering through his mail while he holds a parcel in his arms. He’s in a grey hoodie, and for some reason, it makes him look big, and it’s driving you insane. Shit, shit, shit. You pray that he doesn’t turn around and see you.

“Hey. Good evening y/n”, San greets cheerily. You force a smile, “Good evening San.”

San has his eyes on you, and you swear he’s eyeing you down—probably judging you for being drenched and shit.

“Looks like you reached back just in time”, he teases, and you pout.

“I feel like a drenched dog. Is this how dogs feel after a shower?” You reply, brushing your hands through your wet locks, all in an attempt to stop yourself from staring at San laugh—his voice is hypnotic enough to make you melt into a puddle already. The cold air from the air conditioning hits you once more, and this time you’re beginning to shiver uncontrollably on top of struggling to open your damn letterbox and not looking like a circus in front of your crush.

You focus on fidgeting with your letterbox keys, your fingers reaching out to snatch the letters. When you close the latch, San has his hoodie unzipped, and he’s removing said outerwear.

“San, what are you-“

He’s about to hand you the hoodie, but he instead opts to put his parcels in your hands, and he fucking fits the hoodie around your shoulders, and when he does, his smell floods your senses. He smells like a mix of floral—with hints of spice and citrus, and although for a brief moment, you have it locked in some part of your brain. His fingers brush against yours as he takes his parcels and letters from you, and it doesn’t help that he’s in a black shirt that hugs his biceps, shoulders, and chest a little too well. You barely muster the strength to peel your eyes away, feeling your heart flutter when his fingers brush against yours as he retrieves his packages back from you.

You look up, hoping that the fluorescent lights don’t highlight the heat that’s rushing to your cheeks. You’re still shivering, but suddenly you don’t feel as cold as before.

“Thank you, San”, you smile. “I’ll wash it and return it to you ASAP.” San smiles in response and the both of you walk to the lift together, light conversations and laughter filling the spaces as your body and your heart gradually warm up.

San is exhausted—he’s been at the lab back to back, drafting report after report, and it’s been taking chunks out of him. Palm against his neck, he tilts his head, shutting his eyes as he stretches his neck, and then he sighs. His superiors finally approved his reports and now he has the god-given chance of going home and catching up on his sleep for the night.

The muffled sounds of his doorbell stir him up from his sleep. He doesn’t shift for a couple of seconds. Then his hands shift across the bedsheets to feel for his phone. The doorbell sounds a couple more times and San grunts in his groggy state, his fingers hitting against the edge of his phone, which he pulls closer to him to check the time.

It’s 2 pm. He crashed for 14 hours last night.

He slowly sits up, letting his sight adjust to the afternoon sun filtering through his windows before he walks over to the front door. He’s slightly grouchy from the amount of sleep he clocked in, but as he swings the door open, the remainder of his sleep dissipates when he sees that it’s you standing before him.

“I’m sorry, did I wake you up?” You ask, rubbing your neck. “I wanted to return you this..”, you bring up a paper bag to San’s view. San is still registering this.

“But you weren’t home for the past couple of days, and I don’t have your phone number..”

San blinks. Then his hands reach out to take the paper bag, and his eyes glance downwards.

Ah, it’s his hoodie.

He looks up back to you. “Thank you. Don’t tell me you’ve been coming here every day to try to pass me this?”

“Yes and no..?” you answer with a smile. It spreads to San, who suddenly feels a shot of guilt for making you come to his unit when he wasn’t even there half of the time.

“I’ll treat you to dinner for the trouble I’ve put you through”, he says hastily. He thinks the way your eyes widen and how pink is flushing at the tip of your ears is so adorable, and then he cuts you off before you attempt to decline his offer, “Pass me your phone.”

The phone in your hand is in his now and he types in his phone number before he hands it back to you.

He leans in slightly closer, and there is a particular scent that slowly starts to make its way to his brain. Is it coming from you? For some reason, he hasn’t been able to get it out of his head since the day he lent you his hoodie. And there it was again, faint, but it was definitely there.

“Is there anything else I can help you with, y/n?”

He’s almost disappointed when he sees you shake your head, but at the same time, he has lab work to do, so he shuts the door after he sends you off with a smile, not knowing that you omitted that you wore his hoodie a couple more times after washing (mostly due to the cold weather).

He drops off the paper bag on his bedroom floor before he heads off to his home lab.

Unfortunately, the extra 14 hours of sleep still doesn’t spark inspiration for his chemistry, and he ends up spending barely an hour in his lab, mostly tending to his flowers, before he decides to call it a day.

San is back in his bedroom, and he decides to unpack his hoodie from the paper bag. His hands reach into the bag and retrieve the hoodie, and when he unfolds the hoodie, his mind immediately hazes at the scent coming off the garment. Fuck. It’s even more prominent. It’s the scent that he can’t get out of his fucking head, and now it’s pretty much in his hands.

You smell like fucking heaven, San thinks, placing the outerwear under his nostrils once more, inhaling, the smell completely entering the crevices of his mind. He groans and curses at the way his erection is pushing against his pants just from your fucking smell. It’s more than just the detergent you use—it’s so much more intimate and intoxicating than that, and it’s undoubtedly driving San fucking crazy. He’s so sure that this is the scent that he’s been chasing after.

San walks over to his bed, comfortable on the mattress while he pushes his pants past his thick thighs, his cockhead pushing against his underwear, forming a dark and wet spot. He inhales shakily, teasing himself, the precum thickening and staining more of his underwear. It doesn’t take him long to kick off his sweats and underwear completely, letting his cock spring out with a relieved sigh, before he slowly starts fucking his hand while his other hand has his head filled with your pheromones.

The thought of you on that rainy evening, the way the rain had drenched your white shirt through, your bra showing, cupping your tits so fucking teasingly. San wonders if you did it on purpose because he would have just ripped your shirt open right then and there. His repressed fantasies begin to bubble up—the thought of him inviting you to his unit instead, letting his hands feel you up, making sure your goosebumps are from his touches rather than the cold because he swears he can warm you up quickly. He would press himself against you, taking in your scent, before he’d slip his hands underneath your pathetic white shirt, cupping your tits, then sliding your pants off—he knows he can’t even wait till the both of you reach his bedroom—the furthest the both of you would go? The fucking couch.

Your smell floats, and it’s dragging him deeper and deeper. San bucks his hips against his hand, soft moans pouring out his lips, whining your name against the fragrant garment, his precum turning thicker by the minute. He’s liked you ever since he met you when you first moved in, and now you’re filling up every part of his olfactory senses. He’s desperate to fill you up with him, make sure you’re holding your shirt up with your teeth, your eyes filling up with tears as he slams his cock into your warm pussy, over and over, forcing yourself to stay quiet so the neighbours don’t hear.

Fucking hell. San’s thighs shake slightly at the thought of it. He takes another inhale, and it’s like a dopamine reset once more, perfect at the moment when he’s bringing himself to the edge. Your voice echoes in his head, the pretty sounds you’d make, the expressions that he would indulge in for himself.

Thick streams of cum bubble from his silt, and he almost suffocates himself from the sick pleasure of burying his face in his hoodie drenched in your scent, he catches his breath as the scent slowly fades when he pulls the hoodie from his face, panting from an orgasm that he knows will never be enough one time.

As San washes off his high in the warm showers, he decides to attempt to recreate your scent, wanting to keep it all for himself. And he knows just a hoodie isn’t gonna be enough.

You’ve been flipping your apartment upside down, looking for your panties. At first, you didn’t notice that one pair went missing—chalking it off as you misplacing your laundry. But when the second one you swore you dropped off in the fresh laundry hamper disappears, along with a third, you realise something was amiss. You retrace your steps—you did have a couple of people over recently, but the majority of them were your girl friends, if you minus off how you and San have been going over to each other’s places for meals ever since the both of you exchanged phone numbers. Undoubtedly, your feelings for him have grown exponentially, especially when the both of you spent time with each other in (almost) close proximity. San had always been polite and helped around with cleaning up the dishes, and he had a very endearing habit of leaning in closer to you—whether to just tease you or to hear you better—it would never fail to make you act flustered around him before you would roll your eyes and push him away.

Needless to say, the relationship had blossomed since that rainy evening. You just didn’t expect to grow so close with your apartment complex crush, and while there were nights where San’s face, San’s voice, San’s body would bubble up to the surface when your orgasms washed over you, leaving you squirming and shy once the post nut clarity hit, you thought to yourself that the relationship between the both of you was good enough for now.

You scratch your head, racking your brains as to where your panties might have magically disappeared to. You’re lost in thought until the ping from your phone brings you out of it. You go over to check, and it’s from San—reminding you of dinner at his place. Right, the panties can wait for now.

“I hope I’m not late”, you smile as San opens the door for you to let you in. San returns it, “No, I just placed the order. It’s gonna take awhile.”

You take a seat on his couch. No matter how many times you’ve been to his place recently, you always feel that it’s still so spacious.

Then he breaks your train of thought.

“Is there something you’d like to do while waiting?” You let your eyes wander around his apartment again, and they land on the potted plants on his window sill.

Your eyes dart away from how San is staring down—his body is facing towards you, giving you his fullest, and it’s making you slightly self-conscious.

“I’m wondering what you’re always so busy with.”, you say. You’re ready to be rejected when San doesn’t answer right away. Right, it’s probably something personal to him too. But you can’t help but overthink when he doesn’t reply immediately sometimes. It makes you feel so childlike.

He stands up, gesturing you to follow him. “It’s a little embarrassing”, San replies as he guides you to the tightly shut door. He presses his fingertip onto the keypad—it lights up green and San pushes the door knob down, and the door pushes open.

It is as if it is another world. The lights are dim and the air is a lot cooler, albeit slightly more humid thanks to the myriad amount of plants littered around the room. He has so many species—differentcolours and different flowers. The scents hit you next, the floral scent floating around your nostrils at different intensities.

“A whole nursery?” You exclaim, walking near to some of the flowers.

“Yes and no. It’s more of a lab”, San corrects you, walking over to the heavy desk just full of lab equipment. “Sorry, it’s kinda messy.”

You shake your head, still taking in the sight of his botanically busy room, amazed.

As you near more of the equipment, the scents grow stronger. The whole lab smells so fragrant, and you’re surprised that it’s not overpowering, to say the least.

“So, what do you do here exactly?” You ask, taking another whiff of the fragrance while staring at the rows of test tubes before you.

“I make scents. It’s just a side hobby of mine on top of my research”, San explains. He picks up a test tube and gestures you to take a whiff, and so you do, pleasantly surprised at how much the scent smells just like him.

“Then what’s your little project now?”

San pauses. He doesn’t look you in the eye for that split second. As he parts his mouth to answer, the doorbell rings, and it jumps him out of his thoughts. The food is here.

Seated across San, as you always do, San is plating the takeout while you prepare the utensils. The topic of his lab comes up again, but you completely forget about asking about his projects.

Midway through the conversation, the rice cake that you were trying to eat somehow slips off the utensil and drops onto your clothes, causing you to jump in surprise, somehow toppling your plate with the leftover sauce, on top of staining on your clothes, much to your dismay.

“Shit”, you curse, casting an irritated glance at the splatter on your clothes. The plate clatters on the floor. You stand there, slightly dumbfounded at the situation. You’re wondering if you should just head home to change out, considering that your unit isn’t too far from his. But before you have the chance to bring up that suggestion, San cuts you off.

“You can drop your clothes into the washing machine. In the meantime, you can borrow my hoodie. It should be on the clean laundry hamper.”

“San-“

He turns to you with a comforting smile. “It’s fine. Rice cake sauce isn’t the easiest to clean off when you leave it for too long. I’ll clean up the floor.”

You realise arguing with him isn’t work out in your favour, nor will it get the rice cake sauce off your clothes any quicker, so you decide to heed his words and head to his room.

Undressing yourself once you shut the door, you drop your soiled clothes into the washing machine. It was then you realise that you are pretty much naked, in Choi San’s fucking bedroom. Struggling to keep your head out of the gutter, you decide to focus on finding that damn grey hoodie. Your eyes scan his room, trying to search for the grey hoodie. And your eyes land on a thick-looking piece of garment on one of the laundry hampers. You walk over to pick it up.

You put his hoodie over, and there it is again—the spicy citrus smell. Choi San’s smell. Your thighs push against each other a little tighter this time. Then something in your peripherals catch your attention—a lace garment. You inch closer, and your heart drops.

It’s a pair of lace underwear.

Fuck. Is he seeing someone and he didn’t tell you? A thick lump forms in your throat.

And then it goes away when you start picking up another two more panties from the hamper, and the realisation hits you like a fucking truck—these are your fucking panties.

Things are not adding up in your brain, that’s for fucking sure.

At that moment, San bursts into the bedroom, and a panicked expression scribbled across his face. His eyes are blown wide open when they land on the three pairs of panties in your hands.

You stare back at him, almost mirroring his expression, the only difference being confusion for you instead.

The corner of San’s lips pull into a half smile. “Oops.”

“San, what’s the meaning of this?” You ask, feeling your face flush rapidly.

“Well”, San pauses. “you asked what scent I’m making next right? It’s yours.”

“My scent?” You echo back in question to him. San sighs, his shoulders relaxing as he inches closer to you, trapping you underneath him when you finally hit his bed.

“Yes, darling. Your scent”, his voice almost turning into a whisper, dropping octaves lower. “You’re so cruel—keeping something so intoxicating to yourself.”

You swallow hard. San’s eyes still reflect his usual gentle demeanor, but now it’s slowly being tinted with something else. Something more ominous. Despite that, it only draws you in, like a prey being slowly hypnotized by her predator. You should be shocked, terrified even, but the only thing streaming through the nerves of your brain is the internal begging for San to just eat you up right now.

You suddenly realise that the hoodie isn’t zipped up, the outerwear slipping down your arms. You remain still, your heartbeat slamming against your ribcage.

“You can run out of my apartment now. I’m giving you five seconds”, San tells you, and your mind is spinning at the thought of him even giving you a chance to leave.

Five seconds pass. You’re still staring up at the male above you, whose lips are curling into a satisfied smirk.

His fingers cup your jaw, and he tells you, “Open up.” Sparks splatter across your eyelids the moment his lips collide with yours. You pull him closer on instinct, the feeling of his thick erection behind the two layers of fabric sending you into an orbit on top of his tongue teasing yours. He pulls back, licking off the strings of saliva between the both of you. His gaze is locked onto yours.

“Please? Let me taste you. I promise I’ll make you feel so fucking good”, his request sounding more like a beg. Your mind is hazy. Choi San? In between your fucking legs? You swallow hard, and then you nod.

San lowers himself to your clothed cunt, his eyes shut in bliss when he presses himself against your pussy.

“Heaven”, is all he mutters, his eyes casting you a glazed expression that was definitely about to drive you fucking insane, before his fingers pull against the waistband of your panties, slipping them off you.

The moment you feel his tongue press against your pussy, your mind threatens to shut off. San is breathing heavily against your soaking pussy, taking in the sight, taste, and smell of what you’re finally giving to him. Every time your thighs jerk to shut at the sensation of his tongue licking you up, his hands push you open for him forcing you to take his tongue in your cunt, and it’s wiping out any remaining rational thoughts you didn’t even know you had.

Your fingers tug against his scalp, pushing your hips deeper onto his tongue, your back arched from how fucking good he feels. His tongue is lapping you up, teasing your clit over and over again once he hits the sweet spot, his fingers leaving imprints on your thighs when he hears you whine and moan his name.

All San can think about is how fucking amazing you taste—he knew it would be another fucking level than pressing his nose against the fabric of your panties and fucking into his hand for the past few weeks, but actually letting you fuck his face? He’s on fucking cloud nine.

His glazed-out eyes shift to look up at you, watching the way you’re squirming under him, the sounds of his wet tongue fucking you, tasting you, echoing around his room. Your cream and pussy are the only things he can register, and he wants to keep it for himself, forever.

“S-San-“, you cry out, your mind just threatening to blank out at every flick of his tongue. He’s building your orgasm at such a dangerous pace, and tears are pooling at the corners of your eyes when you feel something funny bubbling at the pit of your stomach. “I think I’m gonna fuck-“

“That’s it. Let it go for me. That’s a good fucking girl”, San encourages, before his tongue presses against your clit, giving you another lick before white washes over you, your cunt pulsing violently against his tongue from the sheer pleasure, then clear fluids splattering onto San’s pretty face—who seemed unfazed, considering he’s still lapping your cunt up, while you’re almost thrashing above him as the overstimulation starts to sink in. Your moans sound like cries when you beg him to stop. San doesn’t relent, and he only stops when he suddenly whimpers, switching over to kiss your thighs, decorating your plump flesh with love bites. He pushes a finger in, letting you stain and coat his fingers, enjoying your whines before he pulls out and towers over you.

“Fuck, if I’d known you’d taste this good, I would have stolen your panties sooner”, he mutters, cleaning his fingers with his tongue, desperate to taste you again.

You’re catching your breath from going through the most mind-blowing orgasm, watching San pulling his shirt over his head, and then slipping out of his sweats, your breath caught in your throat when his fat cock comes into view, thick and heavy, and covered in thick cum.

San’s fingers curl around your neck, and he lowers himself to litter kisses across your neck and jaw, it’s giving you goosebumps, your arms automatically wrapping around his neck to pull him closer.

He pauses right at the shell of your ear.

“I want to wear you over and over again. I want to lock you up in me—bottle you up so I can keep you for myself.”

“Then do it. I’m here for you to dip into your pretty little fantasies in, San.”

You swear you see something snap in the poor male, especially from the way he takes a deep inhale—shakily— before he parts your lips with his, leaving you breathless when your little steamy make-out session ends.

“You don’t know what you do to me, darling”, San cautions when he pulls back. His hair is tousled but fuck, he still looks so fucking good. “And I’m not stopping even if you’re screaming.”

Fuck.

He fucks his hand, soft sighs leaving his lips, as his cum dribbles down his length, before he lines up to your hole and pushes in easily.

You hear him groan above you, your eyes are fixated on the way he’s losing himself in your pussy, and your mind is finally growing blank the more his cock fills you up. He’s stretching you open so fucking good, filling you up to the hilt.

“You’re squeezing me so much, darling. Fuck. Are you fucking kidding me?” His eyebrows are scrunched, his hands holding your legs up while he lets you adjust to his cock.

But he doesn’t warn you before he starts moving, his impatience completely overriding any ounce of rationale he has left in him.

“So good. San, you feel so fucking good”, your moans sounding like cries whenever his hips snap against yours, the obscene sounds only adding to the tension.

“You take me so fucking well, darling”, San’s voice is ringing in your ears. “Look at your fucking pussy just swallowing me up like that.”

You don’t even reply to that, your eyes are rolled to the back of your head, and your head is somewhere in fucking heaven where San is definitely fucking you into.

Just when you feel that you were about fucking fall apart on his cock, he pulls out, and you barely manage to catch your breath when San instructs you to turn over. You do, your ass up for him, and he enters your cunt once more, before fucking into you from the back. You don’t fucking know how, but you swear that his cock feels even thicker from the back.

His hands press against your hips, fucking you deep before he lets his hands slide down your body and he stops at your neck, gesturing you to look up at him as he leans down to press his lips against yours—all while rearranging your guts from the back.

He lets you pull back when you feel your neck is growing sore, and then he puts his body weight onto you, his arm tucking underneath your neck.

“Such a good fucking girl for me. You feel so fucking amazing”, San whispers, tickling every crevice of your brain as he presses his nose against the curve between your neck and shoulder, his thrusts turning more like ruts. The arm lock around your neck isn’t cutting off oxygen thankfully, but the thought of him choking you out only drags you closer to your high.

“Cumming, I’m cumming San-“, you whimper, tears trickling from your eyes from how much his cock is constantly hitting in such deep fucking spots of your pussy.

“Me too, babe. Gonna fill you up so nice and good, that’s what you’d like, right?” San teases, his cock twitching in you before he groans, his warm cum filling you up so good right at the same time your orgasm hits you once more, making you squeeze even more cum from San, perfectly milking him dry in your pussy.

“So fucking perfect”, you hear San mutter, and you can’t help but flush, even though he just fucked every ounce of sanity out of you. His lips trail down the nape of your neck, his eyes are locked onto you, hazy and tinted with a hint of a growing obsession you could never tell.

He’s not letting go of you.

#ateez #ateez scenarios #ateez fanfic #ateez imagines #ateez x reader #ateez smut #smut #ateez fic #kpop smut #choi san smut #choi san ateez #ateez choi san #choi san x reader #choi san #san ateez #ateez san #san x y/n #san network #Spotify

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delosconsulting · 1 year

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IETM/ IETP and IAF Services Provider in india

Delos provides Class IV Interactive Electronic Technical Manuals (IETMs) revolutionize how complex information is delivered and accessed.

#ietp #ietm #s1000d #india #air force network #services #bangalore #delos #softwarecompany #iaf

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sentient-rift · 5 months

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(Suddenly, Thanos snaps his fingers and wipes out half the universe.)

"Oh, not again..."

"Seriously?! We're doing this again?!"

"Curse you, Thanos!!"

"Not on my watch! The Infinity Stones won't work here!"

(RiFT snaps his own fingers and reverses the effect.)

"WAAAAAAH!! THANK YOU, RiFT!!! I REALLY HATE THAT MEME!!!"

"Of course. No meme is going to take my friends away from me."

#mystery data (anon)#humor program #Thanos meme #shy snake adept (elise)#burnerman has logged in (ic)#mu's sole survivor (solo)#em wave change! on the air!#lone rogue of mu (rogue)#sentient dimensional rift (RiFT)#azure striker gunvolt #megaman battle network #megaman star force #mega man zero #(You seriously tried to snap my muses away again knowing RiFT was here?)

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soarrenbluejay · 6 months

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Supervillains for a community. (Well, except those jerks over in Gotham, insular lot, but they’re they’re one problem) Of course they do- supervillains are a group defined by strong opinions and a willingness to see them through, often with a healthy dash of societal failures and trauma as a catalyst.

The fentons, while not active even on the online message boards, are well known and explosive when they do show up, full of fascinating insights and hours long rants on mad science on hair pin turns courtesy of that ADHD attention span. Bit of the cryptids you feel honored to bump into kind of deal. Besides, like a good quarter of the community as it aged, they’d settled down and had kids (not necessarily in that order) and taken it very seriously! Out in the middle of nowhere, where even the most fearsome government outpost members, the local branch of the IRS, quake before them in fear. Out of the way.

Reveal gone okay-ish, Danny moves to Gotham still to get some air bc now things are Akward and he landed that engineering scholarship which is loads better than any other college would give him with his track record. So- the mysterious Fenton children are finally crawling out of hiding! Everyone is psyched! And roll in to Gotham en masse to witness the fireworks!

Except Danny is Determined To Be Normal. He’s had enough of the throwing himself into harms way shit for a lifetime- he wants to be free to peacefully built Rube Goldberg machines and unintentional increasingly complex bombs to his hearts content. JAZZ, on the other hand- the coveted token Normal One, has finally snapped! She’s watched her baby brother she practically raised throw himself into danger over and over and could do nothing, and now that she’s exposed to this whole network of superheroes outside of small town Amnity, some of those uglier emotions are coming out. And boy is she pissed! And can’t afford to show it much while filing the paperwork to have Arkham legally razed to the ground!

See I love this idea of like, niches in superhero society. A villain the heroes know they can plop their kiddo down with for an exciting afternoon brawl while they take care of a particularly grisly case and come back to a few hours later ranting about some new life lesson and a new move they really want to try. A villain who has a functioning moral compass despite their somewhat batshit long term goal and you can contact to fuck with another villains’s plan so they can laugh at them and you can have an easy afternoon. One who pries up hostile architecture and fills in pot holes, idk man. Get creative here, there’s such potential!

So Jazz becomes a Training villain- someone the heroes know their sidekicks will walk away from in a fight 100% of the time, usually with some new lesson to ponder and only a couple of bruises. Sometimes even snacks!

She also absolutely ambushes mentors to check that they’re worth the kiddo, which they appreciate once they get over being jumped in a dark alley by a 7 foot Amazon trained force of nature. They are not used to being on that side of the jumping, it’s a little unnerving.

(Yes, she low key adopts Shazam upon checking in with him on cursory ‘is the main hero of this city and asshole’ checkin. Yes, the super clones get yoinked out from under Superman’s negligent thumb to go have a blast with Ellie. What about it?)

This however only encourages more assorted weirdos to crawl out of the woodwork. It’s not often one of their own forfeits their potential spot for the running of the coveted Most Normal I Swear prize, but when they do it’s bound to be good! But jazz is off hounding various heroes and punching the faces in of pedophiles and shit whenever there’s no cape within easy reach, and so is a mite bit harder to contact than Danny, who has innocently gotten an apprenticeship under a clockworker for access to their workshop and is gleefully going about doing nerdy shit with great abandon.

Plus this is Gotham. No one gives a shit if someone in the Mad Alchemist uniform and still smoking from their latest experiment pokes their head in a window to bother the local shrimp teen- none of the usual social rules apply, everyone’s crazy here! So everyone drops any and all attempts at masking and just acts their genuine unhinged selves, much to the alarm of the Bats and frustration of Danny.

Bc he cannot get these mfers to go. Away. Even liberal use of the creep stick has little effect when the interloper is calibrated for an opponent with super speed or laser vision or whatever, and he’s trying to maintain his guise as a Normal College Student Do No Investigate.

So he calls in the big guns. He’s not super active in the supervillain kids group chat ever since things in amnity calmed the fuck down post becoming King and then immediately using a loophole that says he will not take the throne until he is grown, as defined by finishing learning his trade a la the medieval standards Pariah set up. So he can just take his sweet ass time with his graduate degree and out of inter dimensional bull shit that much longer! Point is, he hasn’t taken the chance to rant over there in a while, so his Crazy friends are getting a lil worried.

The change to come over and shout at their batshit crazy but (mostly) well meaning parent AND see Danny? Score!

The bats, however, are getting awfully suspicious about this one kid that villains from all over the country are flocking to, especially young and upcoming ones as of recently! And he’s acting his engineering course- all the worst rogues are known to have flown through their PhD studies prior to Cracking. They seem to have a real problem on their hands with this Fenton guy.

#dp x dc #dc x dp #mad science #supervillain community #bonus points if you can pull out some super niche comic villain #justice for kite man #local child of a crazy chemist: so you know that trick you showed me with the soda and the reaction that could turn into just like all foam #Danny: yeah and also back the fuck up #lcoacc: so it’s been like my comfort food right but like I started wondering what you could do #danny: oh no (he says while making what amounts of an overachieving smoke bomb)#lcoacc: so I was like what if I add more of a base to it so it could be solid and then maybe just like a LIL acid to see what happens #Danny: oh ancients #lcoacc: but then the killjoy supes came in a ruined everything from where I was ruining lex Luther’s day #Danny:… did you get in on camera #lcoacc: OF COURSE. oh also like everyone ever if coming over for a sleepover lol #Danny: WHAT I CANT FEED YOU MONSTERS #lcoacc: no worrries we’ll rob a bulk store or something lol #Danny: nO

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kairawrites · 2 months

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off track.

minors dni 18+, thanks!

🌺masterlist🌺

pairing: lewis hamilton x black!reader

author's note: careful kaira, your Lew fantasies are showing. this is not edited, didn't need to chicken out of sharing it.

Summary: Keeping your relationship a secret is tough when Lewis can’t keep his eyes or hands off you.

Words: 2254

On track, Lewis Hamilton is fast, calm, and laser-focused, with an instinct for precision that makes every lap feel effortless. His driving is a masterclass in control, blending speed with a strategic mind that sees opportunities where others see limits. As the adrenaline surges, it sharpens his senses, fueling a relentless drive to push boundaries and seek perfection, making him not just a competitor but a force of nature on the asphalt.

Off track, he's slow and relaxed, with movements that are unhurried and deliberate. He savors each moment, finding joy in the simple pleasures and beauty around him. His demeanor is calm, almost meditative, as he takes the time to appreciate the world outside of racing. When he speaks, his words are thoughtful and measured, often turned to praising others and acknowledging their efforts. His humility shines through, as he effortlessly uplifts those around him, offering encouragement and gratitude with a sincerity that reflects his deep respect for people and life.

These habits carried into the evening, which had stretched far longer than he preferred. The event was a glittering affair, filled with familiar faces and the kind of small talk that came with the territory. It was an opportunity to converse with celebrities from different industries, and networking—a skill he had honed over the years—was second nature to him. He moved effortlessly from one conversation to the next, seamlessly blending charm and intellect. The number of introductions, handshakes, and posed smiles under the barrage of camera flashes blurred together, each interaction a practiced routine.

Yet, despite the buzz and the endless flow of champagne, his attention was elsewhere. His thoughts kept wandering back to you, the one person who stood out in the sea of glittering gowns and tailored suits. Every so often, his eyes would seek you out across the room, lingering on you as you moved through the crowd. He found himself captivated by the way you smiled, the way you laughed at some offhand remark, and the way you carried yourself with effortless grace.

The conversations around him faded into the background as Lewis watched you, his focus narrowing until you were the only person in the room who mattered. Each lingering glance he sent your way was filled with unspoken thoughts, a silent pull that neither of you could ignore. Even as he navigated the demands of the evening, you remained at the forefront of his mind, an irresistible presence that drew him in, no matter how much he tried to stay engaged with everyone else.

A month--that's how long it's been since he's last seen you. Work obligations, on both ends, proving to be an obstacle. It wasn't ideal for your reunion to be at such a public place.

The stunning emerald, green gown that flowed like liquid silk, the color a striking contrast against your deep brown skin, making you look like a jewel amidst the crowd. The gown featured a plunging neckline and a thigh-high slit, adding a hint of allure while maintaining an air of sophistication. The rich green fabric caught the light with every step you took, highlighting the gown’s luxurious texture and making you the center of attention. You stood out so brilliantly that you attracted the gaze of every man in the room.

Most men would scowl at the idea of other men admiring their girlfriend, but their attention didn’t spark jealousy in Lewis. Instead, he admired each detail of your ensemble, knowing that every element was tailored to suit his taste. His eyes were drawn to the plunging neckline of your gown, where a delicate necklace nestled against your skin. The necklace, a gift from him, was a masterpiece of craftsmanship: a simple yet elegant silver chain adorned with a single, brilliant diamond pendant. It shimmered subtly, catching the light with every movement you made. Lewis couldn’t help but feel a deep sense of pride, seeing how the necklace complemented your beauty and how, despite the undercover nature of your relationship, every detail was a reflection of his admiration and love for you.

Tonight, his hello came in the form of his touch, his fingers brushing against yours with a gentle, intimate caress as he removed the empty champagne flute from your hand. You felt a shiver of warmth at his touch, a familiar sensation that sent a flutter through you. He replaced the flute with a glass of wine, his right hand settling possessively on your hip for the briefest of moments. His touch reassuring, grounding, as his thumb dragged along the fabric of your gown resting against the small of your back.

“Stunning as always, Ms. Y/L/N,” he notes, his touch tracing the curve of your hip. Lewis leaned in slightly, his breath warm against your ear as he adds, “I was hoping we can find a more private place to talk later.”

You sipped your wine, the cool liquid a sharp contrast to the heat of his touch. With a cheeky smile, you responded, “You expect the man of the hour to disappear unnoticed?”

He nodded towards the bartender, signaling for a refill of his whiskey. As he turned back to you, his eyes held a playful glint. “You’d be surprised what I can do, love,” he said with a grin, his touch leaving a sudden chill as he withdrew his hand. His gaze swept the room, taking in the crowd with a calculated look, as if considering the best way to make his escape without drawing too much attention.

Accepting his glass, Lewis took a leisurely sip, savoring the rich taste of his whiskey. His gaze returned to you, and he shamelessly took in every detail of your appearance. His eyes roamed over the elegant curve of your neckline, the way the gown accentuated your figure, the length of your thigh, down to your ankle. Retracing each feature, the corner of his mouth turning up as his gaze traced the curve of your lips.

Despite the warmth and familiarity of his gaze, you felt a twinge of nervousness. Each time his eyes meet yours, they seemed to pierce through the layers of confidence you typically exude. The intensity of his admiration, though flattering, made your heart race slightly. His gaze lingered with an intensity that was both flattering and unnerving, causing a delicate warmth to creep across your cheeks. The heat spreading from your head to your toes, causing you to find relief in the wine you held. Despite your surroundings, and the respectable distance between your bodies, you could feel the weight of his attention, the way it made you acutely aware of every movement and every expression, as if Lewis could read your thoughts with just a look. It was something you haven't gotten used to and probably never will.

The way his eyes had a way of making you feel like the center of his universe, which was both exhilarating and a little unsettling.

You cleared your throat, shifting your gaze to his emptying glass. “Congratulations on your Grand Prix, Lewis. Looking to unwind tonight?”

“In more ways than one,” he replied with a grin, his eyes twinkling with humor. “Don’t worry, I’m not behind the wheel tonight.”

You giggled, your eyes meeting his with a playful challenge. “Looks like you’re trying to get into trouble.”

His smile widened, and he leaned in closer, his voice dropping to a low murmur. “Promise, I’ll save the best kind for you.” He winked, a hint of mischief dancing in his gaze. As he turned back to signal the bartender for his refill, his hand lingered on your hip, creating a warm, comforting pressure. Once his drink arrived, he met your gaze. "As always, the pleasure is mine, Ms. Y/L/N," he smiled before returning to his guests.

And believe me, it was.

Tonight, his eyes admired the chestnut lipstick, noting the contrast of its rich hue against the soft, full curve of your lips. His gaze drawn to the way your teeth gently dug into the tender flesh, a gesture of both contemplation and restraint. His thumb traced the curve of your bottom lip, the touch light yet insistent, encouraged you to release the bite and reveal the full, seductive shade of your lipstick. You had spent time perfecting your makeup, after all, and he intended to appreciate every detail.

Tonight, he spoke praise into the warmth of your ear, his voice softening as his lips and tongue traced the delicate curve of your neck. His gruff tone melted into a whisper, and he pressed gentle kisses to your pulse, each touch sent shivers down your spine. The contrast of his rugged voice with the tenderness of his actions creates a captivating intimacy, as if he’s recommitting and savoring each inch of you to memory.

Tonight, his calloused hands traced the curves of your hips, admiring the gentle dips and contours as he gripped and kneaded the soft flesh beneath the fabric of your dress. His fingertips dragged and lingered, moving slowly towards your thighs, igniting a thrilling heat with each deliberate touch. His senses were flooded with your scent, a heady mix of perfume and warmth that fueled him with a high he could only ever capture on the track. The intensity of the moment, the closeness of your bodies, and the undeniable chemistry between you all combine to create a rush unlike any other, driving him to lose himself in the sensation.

It was the feeling of pleasure he felt with you, that was unmatched by any woman before, which fueled the movements of his fingers as they slipped between your legs. The strokes of his thumbs meticulously hitched your breath, fluttering your eyes closed. The heat of his mouth, sucked against your chest, your neck, the weight of his body pressed you against the chilled bathroom door. The pressure he built weakened your knees, your fingers clinging to his shoulders as you struggled to breathe.

"Lew…"

His brow arched, his teeth catching the overhead vanity light in a brief flash of white. "Hmm?"

Your lips parted, but your voice was caged beneath the shaky breath his touch pulled out of you. The tremor in your chest revealing the effect he had on you, making it difficult to form coherent words. His touch, both electrifying and tender, left you breathless and yearning for more.

You should've tried harder, fought against the voice in your head screaming for you to push him for more. More than just kisses and the warmth of his fingers. The voice urged you to regain control of your limbs, unbuckle his pants, and feel the part of him you'd missed the most--but you couldn't.

All you could think of is how much you've missed this—how every touch, every whisper felt like it had been too long in coming.

"It's been too long," he murmured, completing your thought as if reading your mind. His left hand rested on the base of your throat, the metal of his rings cool against your overheated flesh. His thumb pressed gently against your chin, tilting your face upwards, compelling you to meet his gaze. His touch was both commanding and reassuring, reminding you of the depth of your connection and the longing that has only grown in the time apart. "You missed me?"

Your response fell short of what he wants. The soft nod of your head, before it lulled back to rest against the door was not what he wants. He wanted to hear the tremble in your voice, the shift in octaves, that replayed on a loop in his mind when he tried to recreate the warmth of your touch in his bed alone. He wanted to see the clouded mixture of lust and pleading in your eyes as your hooded gaze holds his, but your eyes are gripped shut denying him what he wanted.

Instead, you responded by gripping his wrist, keeping him in place as he attempted to slow his pace. Your hips rolled desperately, attempting to matching the circles he drew against your skin.

His chuckle washed over you. His lips warm against the corner of your mouth. Despite your attempt of control, he easily regained it. His touch drifting from your clit, dragging painstakingly slow along the outside of your folds.

"Seems you've forgotten a few things. Hm?"

His touch is meticulous, never brushing against the spot you need, leaving you yearning for more. He kissed your lips slowly, the tenderness of the gesture both soothing and electrifying. Sucking against your bottom lip, he repeated the action as your hips instinctively jerked seeking the high slowly threatening to slip away.

With a soft, commanding tone, he told you, “Lemme see those pretty eyes.”

As you obey and lift your hooded lids, his smile widened with a mix of satisfaction and adoration. It’s a smile that starts in his eyes, which crinkled slightly at the corners, and spread to his lips, revealing a hint of his teeth. The smile is warm and genuine, a reflection of the affection and pride he feels as he takes in the sight of you. The pride he feels in knowing that no other man had the same effect on you. There’s a touch of playfulness in his expression, as his tongue passed over his lips.

“Attagirl,” he murmurs softly, his touch returning to your clit.

The content giggle that escaped your lips, melted into a breathless moan coaxing his finger between your slick folds. It was a sound he'd chase until the end of time. Once it was unlocked, he knew soon the sound of his name on your lips would follow.

"...that's what I've missed," Lewis hummed.

#lewis hamilton x reader #f1 fanfic #f1 imagine #f1 x reader #lewis hamilton x black!reader #lewis hamilton smut #lewis hamilton x you #lewis hamilton imagine #black! reader #black reader #x black reader #sir lewis hamilton #lewis hamilton black reader #black reader fan fiction #black reader fic

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