#microbio notes

[er-cryptid]

Measles Virus Entry

Virus attaches to cell

Membrane lipids rearrange

Adjacent halves of the membranes merge together

A proteinaceous fusion pore forms to allow entry

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[dnfity]

i'll be 70 and still thinking about dnf chains

real

[springstick]

100 Days of Productivity ⇢ #032

Thursday, Dec. 12th, 2024: Have I mentioned how much I love microbiology??? I definitely haven't mentioned it enough. Anyway I'm really happy to be done with this semester. I didn't do as well as I wanted to. I'll probably do a recap post when final grades come out. My spring semester is going to be really fun, but I also want to do well.

Today's Study: Microbiology practice exam [1.5hrs] Microbiology flashcards [0.5hrs] Microbiology lab notebook study [1hr] ~3hrs ☆⋆���𖦹°‧★ Today's Final: General Microbiology (12:45pm) Tomorrow's Final: NONE!! ITS OVER ☆⋆｡𖦹°‧★ Today's Self-Care: Going on a run, journaling a LOT, sitting in the snow for a bit, buying my siblings Christmas gifts. ☆⋆｡𖦹°‧★ To-Do Tomorrow: 1. Get my cat safely to sitter's house 2. Get coffee with my professor 3. Completely pack for my trip home 4. Unplug everything except fridge, microwave, and charger 5. Roll up carpets to wash when I get back 6. Vacuum floor 7. Put away laundry 8. Take out trash 9. Finish character sheets for novel

I really tried to balance taking care of myself with productivity this semester, but by the looks of it I got almost straight Bs, so I didn't do great on the productivity front. But maybe that's just a byproduct of putting myself over my grades. But also my grades :(

[mysicklove]

i can’t believe i have to be a real functional college student. can i just look pretty and write smut all day god damnit

[aneurizma]

No one told me that most of my adult male friendships will be this homoerotic

[crystalnotebook]

Was anyone going to tell me that there are several modern human diseases that originated in the Neolithic Era, or was I just supposed to find that out while researching for an Epidemiology assignment?

[bugbbear]

It could be a fungal infection, insect infestation, or something else, but the most interesting answer (and the only one i feel qualified to talk about) is bacteria!

Specifically agrobacterium tumefaciens!!

It has two sets of DNA- one regular set and one Ti-plasmid (specific DNA in a ring). It injects this Ti-plasmid DNA into a plant cell's cytoplasm, where it is integrated into the plant's DNA.

The integrated DNA contains instructions for several things, including hormones like auxin that control growth and are not normally expressed in plants (and therefore do not have a regulation pathway to shut it down). This is what causes the tumors. But the most important thing the injected DNA codes for is for the plant cell to make special forms of amino acids that the bacteria can break down and eat.

Let me say that again. The bacteria cannot break down the nutrients in the soil, so it's making the plant cells do it, and then eating that.

The bacteria is genetically modifying plant cells to chew its food.

Isn't that fucking awesome???

[midoristeashop]

from my microbio notes LMAO

the yaoi wolf is clawing itself free

I have like one more week until finals and then I have more things to share!!

[mercuryflan]

I can only doodle them next on my notes at the moment cause microbio is stressin me out-🫠

[er-cryptid]

Herpes Simplex Virus Type 1

-- also called cold sores or fever blisters

-- abbreviated as HSV-1

-- causes: -> infectious transmission -> stress -> lack of rest -> poor nutrition

-- cold sores form around the mouth

-- treatments: -> antivirals -> numbing medication

.

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[maythedreadwolftakeyou]

Rules: make a new post with the names of all the files in your wip folder, regardless of how non-descriptive or ridiculous. Tag as many people as you have wips. People send you an ask with the title that most intrigues them, then post a little snippet or tell them something about it!

ohhhh well this is going to be humiliating 😭

first of all. bold of this meme to think i have one single cohesive WIP folder rather than store random progress files in 7 different subfolders in various locations on my computer, and a handful just on my phone. HOWEVER. lets see how many i can track down tonight. second of all as i have stated before i am a CHRONIC writer-not-a-sharer so uhhhhh some of these are true WIPs i intend to finish Someday, some are truly abandoned, some were just character explorations i never even intended to share/post in the first place really. i truly do this for Me and everyone else is an afterthought for the most part, though once i start posting something I am pretty committed to Getting It Done Eventually now.

third of all i am leaving out any fic where i have the entirety shared somewhere. i don't move those to a new 'finished' folder or anything, they just live in the same place i originally saved them forever alongside the WIPs. I am ALSO leaving out the secondary documents any longer work has, which is usually "[original file name] Notes" because I like to use a split-screen approach with an outline/cut sections/random notes on the right and the working document on the left. Where the writing/notes are in just one same document, it's in the list as named.

Fanfiction:

Ascension

AndersJustice

BadThingsHappen

Coffee date

DeathOfClanLavellan

Fade regret prison

Fallout from the Fade

Fallout from the Fade (Doc2)

futility1

Gifts

Grannyquizition

Hawke hurt/comfort

hawke/lavellan convo

Headstones

lucanis

Lucanis character touchstones

Lucanis Lighthouse

Lucanis/Rook boat scenes

Lucanis/Rook lighthouse romance scene

marked up for the crows

MemoryViewing

MythalSolasBurial

NOTES Blackbirds poem

NOTES random/assorted

prompt starts

RyderXReyes

SAM&Ryder

solas poem series

SolasmancyPoem [note: this is not the same one i mention below/actually shared, its a diff concept i didn't use]

SPITE ROOK X LUCANIS INTERUPTION

sten

TrevXCullen

TruthSpellRewrite

[untitled phone note with a big mix of stuff in it]

Vivienne_preWEWH

aaaaaaand then there's the original writing. i am cutting off anything I did before 2017 because god i don't want to think about it

4

AVeryShortPoem

dragonpoem

Fynding

FEMS microbio flash fiction

i could be a wolf for you

love songs to the desert

methylation

NaNoWriMo2017

NaNoWriMo2018

outsiders

ORACLE

pandiculation

PoemsWorkbook

questionnaire

Two weeks to launch

VAULT

honestly i'm sure there's like 30 more original WIPs but it's 2:30am and i can't keep digging so i'm leaving it at the contents of the 3 folders i found first

and then i am putting this down here not as part of the game, but just because i opened the specific folder (and 2 other subfolders within it) and started laughing at the Mess. although it's "finished"/posted so not technically a WIP, this is all my version control documents for Like Teeth Against His Heart which was part of a collaborative zine. so instead of winging it I had my bff beta for me so kept re-saving new copies... I actually have NO IDEA which of these is the REAL final one anymore to be honest. in case any artists out there wondered if the final_FINAL_real.jpg thing also happens to writing: yes.

SolasPoem

SolasPoemdraft2

SolasPoemdraft2_aligned

SolasPoemdraft2_aligned_pages

SolasPoemdraft2_alignedEdits

SolasPoemdraft2_aligned notes complete

SolasPoemdraft2_alignedEdits2

SolasPoem_Final

Jade_Solasmancy_Final

Jade_Solasmancy_Final+Previews

Jade_Solasmancy_FinalNotes

PROPOSED_EDITS_Jade_Solasmancy_FinalNotes

Jade_Solasmancy_FinalNotes_condensed

PROPOSED_EDITS_Jade_Solasmancy_FinalNotes_condensed

jesus christ. anyway. can you tell i'm unmedicated for adhd. well! onward and tagging a random assortment of folks because i can NOT tag 50+ entire people:

@m-m-m-myysurana @anonymous-inquisitor @thebookworm0001 @pikapeppa @sageadvice @bdafic @fourthage

but consider this an open invitation to anyone to share this & tag me in you result, bc i wanna see what people are up to and need more writing friends <3

and thank you for the initial tag @baejax-the-great!!

[studentbyday]

{ 31.10.24 } · { 50 days of routine } · { day 2 }

omg i had the wrong date in the last one, it was the 30th, not the 29th! 🤦🏻‍♀️ it's fixed now... happy halloween to those who celebrate! 🎃🦇

woke up at 6:35 so i could finish my microbio assignment in time ☕ (first win: not feeling so awfully sleepy and all-around terrible upon waking up)

finished the microbio assignment 30 mins before the deadline 💪🏻 (god i hope that sort of cramming never happens again, like, yes do the best under the circumstances and i believe i did, but try to put yourself [read: myself] in better circumstances too if you can, yeah?? [i'm talking to myself])

walk (30 mins) and watch: a video my sister sent me, a video that was recommended in my feed but i didn't actually like that much bc it didn't give me much hope so i'm not gonna share it, a whimsical video 🍃

catching up on immunology from last week 🏃🏻‍♀️

got today's discussion post for global health outta the way 🏃🏻‍♀️

almost done this week's global health module

on another note, it feels like it's been a while since i've ~entered a flow state~ with my work... but i had that today and yesterday as i was searching for articles, reading said articles, and writing what i had learned from them for my assignments. that's probably another contributor to why i feel better now than earlier this week (asides from surprisingly better sleep today than yesterday and actually having finished some important stuff). but boy, am i (still) exhausted and in need of a looooonnngg night's sleep... ���😴

[winterswrandomness]

ro! i was going over the stuff my microbio class is gonna cover next week, and we're learning about mushrooms (well, more like fungi as a whole) and it made me think of you.

side note, fungi are cool as fuck but you already knew that

YEAAHHHHH LETS GOOOOOOO!!!! I hope you have fun!! :D

[charmcoin]

going home and napping. because i feel like the shambling corpse. and then going back to campus and accomplishing things.

list of things includes:

- finishing take home exam for microbio

- writing results section & copying procedure for lab tomorrow

- reviewing the iliad and odyssey in preparation for exam on friday

- reviewing pchem notes if i have time/desire

and when i am done i can go home and play more metal gear solid. as a treat

[ramayayi]

Date: 17.11.24

Checked out all to do tasks on my list

Finished reading Benzene, effects of substituents on Benzene for Org chem. For microbio, read the introductory chapter and cell structure

For pharmaceutical engineering, skimmed through the first chapter

As for physical pharmaceutics, which was lengthy so completed half of the chapter reading today. Remaining shall be done tomorrow.

Watched 2 eco lectures and read a chapter.

Since I am also on substack and I will be posting a monthly work based on dance, so was noting and reviewing a bharatnatyam abhinaya piece depicting Devaki, krishna's mother.

And made a partial to-do list for tomorrow. Will fill the remaining half tasks in the morning after checking out a few of them during the day.

[texasdreamer01]

Atlantis Expedition: Science Division Departments - Life Sciences Department

We're a bit further from the original post, having already done the medical department, so now it's time for the Life Sciences.

Much like the medical department, the notes for this underwent significant revision (nearly entirely re-done), to better granulate expectations for the department's duties and how they interact, primarily, with the medical department. Below is the original estimation, with struck text indicating revisions:

> Head: OC > Contains: Earth biologists, bio- & biochemical engineers, astro/xeno-biologists, botany, environmental chemistry, zoology, microbiology > Function: Auxiliary to Medical Department needs > Examples of function: pharmaceutical synthesis, analysis of unknown species, biological database creation, gene therapies (pharmaceutical adjacent) > Personnel quantity: 1 (Head) + 2 (Earth biologists) + 2 (bioE & biochemE) + 1 2 (astro/xenobio) + 1 (botany) + 1 (envchem) + 1 (zoo) + 2 1 (microbio) = 11 > Personnel quantity: 1 (Head) + 1 (physiologist) + 1 (geneticist) + 1 (astrobiologist) + 1 (xenobiologist) + 1 (microbiologist) + 1 (botanist) + 1 (zoologist) + 1 (biomedical engineer) + 1 (biochemical engineer) + 3 (medical laboratory scientists) = 13 > A/N: Both biologists also have training/specialization in genetics/gene mapping (assists both Carson and Katie), some input in requesting gate missions based on in-house needs > A/N: Focus is on medical logistics and supporting Medical Department needs, research parameters fulfill SGC outlines of studying microevolutions and drug technology development.

Following on the parameters of 1) putting people through the inter-galactic theoretical shredder is expensive, and 2) said gate shredder will only be open for a certain amount of time, the vast majority of this department's work will be geared toward the analysis, creation, testing, and preparation of pharmaceutical drugs and other inventions of medical context.

Think compounding pharmacy but better equipped, and capable of researching new things - this department specializes in medical logistics. Wikipedia has a better description of this, so I'll pull a quote:

Medical logistics is the logistics of pharmaceuticals, medical and surgical supplies, medical devices and equipment, and other products needed to support doctors, nurses, and other health and dental care providers.[1] Because its final customers are responsible for the lives and health of their patients, medical logistics is unique in that it seeks to optimize effectiveness rather than efficiency.

As with most things contrived by the SGC, there's going to be a lot of blended specialties and overlap, heavily bolstered by technological innovation. These are people Carson Beckett likely hired, or at least had a heavily-weighted opinion when Rodney was going through the application packets, because the Life Sciences is at a one-step remove from actually handling patients, and handles a significant amount of labwork and research.

The revised numbers weigh heavily in favour of biologists, due to the sheer breadth and depth of the subject, and the fact that most of these are likely to have some sort of SGC training that would make them well-versed on what to expect on the expedition in terms of disease research and thus treatment solutions.

Unlike the medical department, which handles patients directly in different aspects, this is all one "team". If you're looking for a group of scientists that can technically have the same generic appellation that would make one of them go, "Well, actually-", this is the place to look.

On to the breakdown, notes included:

> Earth biologists  » 2x of these  » Specialties?   ⇛ Human physiology (academic rather than medical context)   ⇛ May function as a knowledge base to study how the physiology of the expedition changes by long-term habitation in Atlantis, assists in studying long-term effects of the ATA gene therapy, development of knowledge base as Earth-based physiology changes in reaction to Pegasus galaxy habituation (exposure to local diseases, eating of local foods, etc)   ⇛ Geneticist   ⇛ Same as the human physiologist, but in a genetic context   ⇛ Studies genetic drift of the expedition and builds knowledge base for comparisons of baseline to genetic mutations that build up over time > Astro/xenobiology  » 2x of these   ⇛ 1 of each  » SGC special  » Studies the species and speciation of non-human humanoid species   ⇛ Imports from studying the Jaffa, Goa'uld, and Replicators (xenobiologist in particular)   ⇛ Overlap with parasitology and immunology/histocompatibility (Goa'uld and Jaffa, respectively) > Microbiology  » "Most microbiologists specialize in a given topic within microbiology such as bacteriology, parasitology, virology, or immunology."  » Studies the species and speciation of bacteria, algae, fungi, and some types of parasites and their vectors > Botany  » Study of species and speciation of plant species  » Outline of botany > Zoology  » Study of species and speciation of non-human animal species  » Outline of zoology > Biomedical engineer  » REVAMP from bio-engineering  » Actually makes the pharmaceuticals based on the feedstocks and processes biochem engineers designed for them   ⇛ Works with biochem engineers to feedback on the design process of drug manufacturing   ⇛ Biologics as well as inert (in comparison) materials for drug development   ⇛ Pharmacology    ⟹ Most likely all drugs are powdered for shelf-stability and ease of transportation     ⭆ So their responsibility in this would be referencing the SGC formulary (how many books to a Frasier) on reconstituting these drugs      ➾ Compounding     ⭆ What about topical prescriptions? Gel-based? Powder for gels, as well      ➾ More complex formulation     ⭆ What about gases, for sedation?      ➾ Probably compressed canisters? > Biochemical engineer  » Would not have existed in the early 2000s as a field related to process engineering, so an SGC special  » Also useful for researching food preservation methods  » Synthesizes information from peers in this department to create pharmaceutical drugs and their manufacturing process > Medical Laboratory scientist  » Does the legwork of processing samples for everyone, so needs a wide range of skills   ⇛ 3x of these   ⇛ Specialties    ⟹ Immunology/histopathology/hematology     ⭆ Human tissues    ⟹ Microbiology/bacteriology     ⭆ Bacterial forms of infection    ⟹ Virology/mycology/parasitology     ⭆ Non-bacterial forms of infection      ➾ Routes of non-bacterial infection > Environmental chemistry  » Role covered under biochem engineering  » Biochem engineers can cover the study of pollution that envirochems specialize in

Environmental chemistry section preserved to properly annotate the revisions, and what their original role was supposed to be (i.e. study pollution to solve Earth's pollution issues).

It occurred to me, while revising personnel lists, that the biologists in particular will need to divide their research into some broad categories, if they want to properly develop their research topics and what category of formulations they would require from the non-biologists in the department.

We have human species, yes, but that can be parsed from Milky Way to Pegasus galaxies, and from there Earth-based humans vs Jaffa (vs Goa'uld), and Pegasus-based humans (presumably humans, as they probably wouldn't know for sure that the Ancients were the default sentient or even default humanoid species in the Pegasus galaxy).

The human microbiome is incredibly important to understanding homeostasis, disease pathology, and various other interconnected factors. Because of this, the medical laboratory scientists will be heavily relied upon to develop cultures for study. I'm willing to believe that they have some nifty adapted technology to help them study all of these subjects I've shoved under multiple umbrellas, in the form of culturing processes, reagents, microscopes, analyzing software, preserving agents/methods, and the like.

After that, testing to see how these diseases - or potential diseases, if someone in the Pegasus galaxy hosts a bacteria, virus, fungus, or parasite that their immune system is natively robust to - might infect a member of the expedition. This is where a lot of back-and-forth would be done between the Life Sciences and Medical departments, so it wouldn't be uncommon to see people like, say, Biro (pathology) and Katie Brown (botany) jointly doing research on a pathogen.

There's already a lot of canonical evidence to support this specialist overlap being a necessary concern, from the the Hoffan drug (and the subsequent Michael arc), John Sheppard's infection from an Iratus bug bite in Conversion, Asurans, Lucius' drug, the crystals of M3X-387, Kirsan fever, Jennifer Keller's infection from something that was turning her into a Wraith hiveship in The Seed, and the Second Childhood parasite.

Depending on the type of infection, a lot of the personnel in this department will coordinate with each other to develop a knowledge base, including potential therapeutic remedies. If something already in stock cannot be used (see: a potential cross-applicability of penicillin), then they might make a request to the head of the expedition for a gate team to travel based upon any information they might have (ex: Teyla and Ronon going out for samples of the Enchuri plant for treating Kirsan fever).

Because of their support role as a department, the fact that all the scientists here can be used as in-house reference for the medical department, and their unique position to recommend gate missions for consideration on the roster, this department functions well as a bridging gap for the various demands the expedition has placed on them by the IOA and the SGC.

Total Life Sciences Department Personnel

Head of Department: 1

Biologists: 5

Engineers: 2

Laboratory Scientists: 3

Botany: 1

Zoology: 1

Total total: 13

I'll be going over canonical personnel such as Katie Brown in their own posts, but for now this is a general accounting of the expedition’s life sciences department.