#prevent autoimmune diseases

[centralbiohubgermany]

Research on Autoimmune Diseases

What exactly are autoimmune diseases?

Have you ever thought of a situation where our body becomes our enemy? Autoimmune diseases refer to a condition in which our immune system tends to destroy our healthy tissue due to an abnormal mechanism called autoimmunity. It is a chronic lifelong condition, and millions of people across the globe are living with it. Most of the time, autoimmune disorders are abrupt in onset, regardless of age, and females are more likely to develop than men. There are more than 80 autoimmune diseases that affect millions of people across the globe. It includes rheumatoid arthritis, Grave’s disease, Hashimoto’s thyroiditis, systemic lupus erythematosus (SLE), antiphospholipid syndrome, psoriasis, multiple sclerosis, coeliac disease, inflammatory bowel disease (IBD), Sjogren’s syndrome, and many more.

Strengthen Research on Biospecimens of Autoimmune Diseases

The growing incidence and prevalence of autoimmune disorders called for the immediate attention of global research to discover novel treatments and prevent autoimmune diseases. Today, medical science has endless possibilities. As far as immunology research is concerned, a lack of a clear understanding of the causes and exact pathway of autoimmunity is the main roadblock to discovering a permanent cure for autoimmune conditions. Against this background, it is of paramount importance to utilize the banked human biospecimens, such as serum, plasma, tissue, and PBMC, isolated from patients with autoimmune diseases. A well preserved, richly annotated human biospecimen can act as in-vitro patient models to intensify more studies on autoimmune disorders. Therefore, powering human biospecimens to foster research can uncover the secret behind autoimmunity and discover disease-specific autoimmune disease treatments.

The largest collection of Autoimmune Disease samples. Order online.

Today, research on human biospecimens has immense possibilities. Therefore, the demand for best-quality reliable human biospecimens is rising exponentially. Understanding the limitless possibilities of human specimen research, Central BioHub unveils a meticulous collection of autoimmune disease samples exclusively for drug and diagnostic research. It provides samples that are ethically obtained from autoimmune disease patients diagnosed with rheumatoid arthritis, inflammatory bowel disease, systemic lupus erythematosus, myasthenia gravis, antiphospholipid syndrome, Grave's disease, Hashimoto's disease, Sjögren's syndrome, etc. Being a marketplace for human biospecimens, all samples are in-stock and readily available for purchase, reservation or quotation. Central BioHub offers human serum samples tested for antinuclear antibodies (ANA), antineutrophil cytoplasmic antibodies (ANCA), antibodies to double-stranded deoxyribonucleic acid (anti-dsDNA), Rheumatoid factor (RF) and more parameters. To find out more about the samples and the ordering process, click here: https://centralbiohub.de/biospecimens/autoimmune-diseases

Central BioHub is eager to provide top-notch human biospecimens with the fastest global delivery. Pave your path to a moon shoot discovery in autoimmune disease research. Let’s start with Central BioHub today.

[antique-symbolism]

(11.28.23)

Living in a dying body,

Stranded on a dying world,

What shall the dying do?

Grind our bleach-white coral bones,

Drown in rising water, our limbs too weak to tread?

How about this instead?

On New Year's Eve, my father, a doctor of the weather said: 

"I believe in the resilience of our atmosphere."

And thus began my year,

With a body set for ambush storms, and unprepared to take my cover,

Hopeful, kicking at the knees that wouldn't last the summer.

But if Dad can see the damning data and give us yet our chance, 

Then I will face the fates that are written in my scans,

Feed the sturgeon lunch at the museum,

Bend slowly to the waterline and whisper this to them:

"I believe in our resilience, too."

[eatclean-bewhole]

Steps you can take now to start taming inflammation:

1. Prioritize anti-inflammatory foods:

•Heathy fats (omega-3s) - Olive oil, avocado, coconut, nuts & seeds

•Fruits high in vitamin C - citrus fruits

•Antioxidants - berries, green tea

•Vegetables -leafy greens

•Lean protein & legumes

•Herbs & spices - turmeric (curcumin), ginger, garlic, cinnamon

•Fermented foods (probiotics)

2. Juice alkaline, antioxidant, & chlorophyll-rich vegetables & fruits. Especially those that are green (kale, spinach, broccoli, spirulina, chlorella, basil, cilantro…).

Chlorophyll is alkalizing, high in antioxidants, & detoxifying. All of which help improve oxygen delivery throughout the body by promoting red blood cell production. Oxygen is like water on the inflammation fire.

3. Anti-inflammatory therapies:

•Hyperbaric oxygen therapy

•Cryotherapy or cold plunges

•Red light therapy

If you’re local, you can visit my friends @upgradelabsriverton and try these therapies.

#antiinflammatory #antioxidants #health #healthylifestyle #healthyfats #nutrition #wellness #guthealth #healthyfood #antioxidant #cbd #organic #antiinflammatorydiet #inflammation #detox #turmeric #chlorophyll #longevity #healthy #healthyliving #holistichealth #painrelief #natural #immunesupport #antiinflammatoryfood #immunesystem #omega #juice #juicing #foodismedicine

[ayeforscotland]

Holy shit.

Researchers at the University of Chicago have been able to create an ‘inverse vaccine’ that can remove the immune systems memory of specific molecules.

Reading that, sounds like a horrendous bio weapon in the making. But the plan is for it to be used to treat autoimmune diseases like multiple sclerosis, type one diabetes and rheumatoid arthritis.

This was already proven to be able to prevent autoimmunity but the new work shows it can be used to treat ongoing autoimmune issues.

Source.

[reasonsforhope]

"The Biden administration on Thursday [August 15, 2024] released prices for the first 10 prescription drugs that were subject to landmark negotiations between drugmakers and Medicare, a milestone in a controversial process that aims to make costly medications more affordable for older Americans. 

The government estimates that the new negotiated prices for the medications will lead to around $6 billion in net savings for the Medicare program in 2026 alone when they officially go into effect, or 22% net savings overall. That is based on the estimated savings the prices would have produced if they were in effect in 2023, senior administration officials told reporters Wednesday.

The Biden administration also expects the new prices to save Medicare enrollees $1.5 billion in out-of-pocket costs in 2026 alone.

“For so many people, being able to afford these drugs will mean the difference between debilitating illness and living full lives,” Chiquita Brooks-LaSure, administrator for the Centers for Medicare & Medicaid Services, told reporters. “These negotiated prices. They’re not just about costs. They are about helping to make sure that your father, your grandfather or you can live longer, healthier.”

It comes one day before the second anniversary of President Joe Biden’s signature Inflation Reduction Act, which gave Medicare the power to directly hash out drug prices with manufacturers for the first time in the federal program’s nearly 60-year history.

Here are the negotiated prices for a 30-day supply of the 10 drugs, along with their list prices based on 2023 prescription fills, according to a Biden administration fact sheet Thursday.

What Medicare and beneficiaries pay for a drug is often much less than the list price, which is what a wholesaler, distributor or other direct purchaser paid a manufacturer for a medication before any discounts...

The administration unveiled the first set of medications selected for the price talks in August 2023, kicking off a nearly yearlong negotiation period that ended at the beginning of the month.

The final prices give drugmakers, which fiercely oppose the policy, a glimpse of how much revenue they could expect to lose over the next few years. It also sets a precedent for the additional rounds of Medicare drug price negotiations, which will kick off in 2025 and beyond. 

First 10 drugs subject to Medicare price negotiations

Eliquis, made by Bristol Myers Squibb, is used to prevent blood clotting to reduce the risk of stroke. 

Jardiance, made by Boehringer Ingelheim and Eli Lilly, is used to lower blood sugar for people with Type 2 diabetes. 

Xarelto, made by Johnson & Johnson, is used to prevent blood clotting, to reduce the risk of stroke.

Januvia, made by Merck, is used to lower blood sugar for people with Type 2 diabetes.

Farxiga, made by AstraZeneca, is used to treat Type 2 diabetes, heart failure and chronic kidney disease. 

Entresto, made by Novartis, is used to treat certain types of heart failure.

Enbrel, made by Amgen, is used to treat autoimmune diseases such as rheumatoid arthritis. 

Imbruvica, made by AbbVie and J&J, is used to treat different types of blood cancers. 

Stelara, made by Janssen, is used to treat autoimmune diseases such as Crohn’s disease.

Fiasp and NovoLog, insulins made by Novo Nordisk.

In a statement Thursday, Biden called the new negotiated prices a “historic milestone” made possible because of the Inflation Reduction Act. He specifically touted Vice President Kamala Harris’ tiebreaking vote for the law in the Senate in 2022.

Harris, the Democratic presidential nominee, said in a statement that she was proud to cast that deciding vote, adding there is more work to be done to lower health-care costs for Americans.

“Today’s announcement will be lifechanging for so many of our loved ones across the nation, and we are not stopping here,” Harris said in a statement Thursday, noting that additional prescription drugs will be selected for future rounds of negotiations."

-via CNBC, August 15, 2024

[surinderbhalla]

What is Lupus- Can it Be Prevented?

Our immune system is a remarkable defense mechanism, shielding us from harmful bacteria, viruses, and other intruders that can make us ill. However, in the case of lupus disease, our immune system mistakenly turns against our own body’s tissues, causing damage. These conditions are referred to as autoimmune diseases. Doctors have yet to uncover the exact cause of lupus, but they believe that…

[truth4ourfreedom]

THE BENEFITS OF IVERMECTIN. IF YOU HAVE CANCER, FREQUENT COLD OR INFECTIONS, MUSCLE SHRINKAGE, CARDIAC ISSUES, CROHNS, HERPES, ETC.

The study was published in the Cureus Journal of Medical Science.  LET'S TALK ABOUT IVERMECTIN 1 – Ivermectin prevents the damage caused to RNA Vaccines.  2 – Ivermectin blocks the entry of Spike Protein into cells.  So, if the person was vaccinated with COVID, they have hope, they have a way to treat themselves through Ivermectin.  3 – Ivermectin is a treatment after Covid and after vaccination, it is an effective medicine in all phases of Covid 19, even before entering the cell, Ivermectin already destroys the virus in the blood.  It only has beneficial effects and no harmful effects in the treatment of the coronavirus.  4 – Ivermectin has a very powerful anti-inflammatory action against Coronavirus.  5 – Ivermectin has a powerful action for traumatic and orthopedic injuries, it strengthens muscles and has no side effects like corticosteroids.  6 – Ivermectin treats autoimmune ailments such as: rheumatoid arthritis, ankylosing spondylitis, fibromyalgia, psoriasis, Crohn's disease, allergic rhinitis.  7 – Ivermectin reduces the frequency of flu and colds.  8 – Ivermectin improves the immunity of cancer patients.  9 – Ivermectin treats Herpes Simplex and Herpes Zoster.  10 – Ivermectin reduces the frequency of sinusitis and diverticulitis.  11 – Ivermectin protects the heart in cardiac overload, in an embolism for example, it prevents cardiac hypoxia because it stimulates the production of basic energy so that the tissue is not destroyed and thus improves cardiac function.  12 – Ivermectin is antiparasitic.  13 – Ivermectin is anti-neoplastic (anti-cancer), it suppresses the proliferation and metastasis of cancer cells, only killing cancer cells and preserving healthy cells, improving the effectiveness of chemotherapy treatment, as it kills cancer cells resistant to chemotherapy, defeating the resistance to multiple chemotherapeutics that tumors develop, and combined with chemotherapy and/or anti-cancer agents, it provides an increase in the effectiveness of these treatments.  14 – Ivermectin is antimicrobial (bacteria and viruses), and increases immunity.  15 – Ivermectin reaches the Central Nervous System and regenerates the nerves.  16 – Ivermectin regulates glucose and insulin metabolism.  17 – Ivermectin regulates cholesterol metabolism.  18 – Ivermectin reduces liver fat in steatose.  19 – Ivermectin protects the liver exposed to insecticides.  20 – Ivermectin attacks the virus wherever it is, regardless of mutations.  21 – Ivermectin serves for the prevention and treatment of coronavirus, surprisingly.  Unproven efficacy is not of Ivermectin, but of vaccines.  22 – Ivermectin, used as a prophylactic agent, was associated with a significant reduction in infection, hospitalization and mortality rates due to COVID-19.  23 - Ivermectin does not attack the liver, since it is not metabolized in it, and if in the intestine, on the contrary, it protects the liver. 

BIG PHARMA DOES NOT WANT YOU TO KNOW THIS.THEY WANT TO SELL YOU THE EXPENSIVE MEDS THEY MAKE BILLIONS ON.

Please read, save and re-blog before Tumblr takes this down.

[sugarcoatednightshade]

thinking about how Humans Are Space Orcs stories always talk about how indestructible humans are, our endurance, our ability to withstand common poisons, etc. and thats all well and good, its really fun to read, but it gets repetitive after a while because we aren't all like that.

And that got me thinking about why this trope is so common in the first place, and the conclusion I came to is actually kind of obvious if you think about it. Not everyone is allowed to go into space. This is true now, with the number of physical restrictions placed on astronauts (including height limits), but I imagine it's just as strict in some imaginary future where humans are first coming into contact with alien species. Because in that case there will definitely be military personnel alongside any possible diplomatic parties.

And I imagine that all interactions aliens have ever had up until this point have been with trained personnel. Even basic military troops conform to this standard, to some degree. So aliens meet us and they're shocked and horrified to discover that we have no obvious weaknesses, we're all either crazy smart or crazy strong (still always a little crazy, academia and war will do that to you), and not only that but we like, literally all the same height so there's no way to tell any of us apart.

And Humans Are Death Worlders stories spread throughout the galaxy. Years or decades or centuries of interspecies suspicion and hostilities preventing any alien from setting foot/claw/limb/appendage/etc. on Earth until slowly more beings are allowed to come through. And not just diplomats who keep to government buildings, but tourists. Exchange students. Temporary visitors granted permission to go wherever they please, so they go out in search of 'real terran culture' and what do they find?

Humans with innate heart defects that prevent them from drinking caffeine. Humans with chronic pain and chronic fatigue who lack the boundless endurance humans are supposedly famous for. Humans too tall or too short or too fat to be allowed into space. Humans who are so scared of the world they need to take pills just to function. Humans with IBS who can't stand spicy foods, capsaicin really is poison to them. Lactose intolerance and celiac disease, my god all the autoimmune disorders out there, humans who struggle to function because their own bodies fight them. Humans who bruise easily and take too long to heal. Humans who sustained one too many concussions and now struggle to talk and read and write. Humans who've had strokes. Humans who were born unable to talk or hear or speak, and humans who through some accident lost that ability later.

Aliens visit Earth, and do you know what they find? Humanity, in all its wholeness.

[heighpubsseo]

Journal of Sports Medicine and Therapy

Sports medicine and therapy is a distinct division of Health Care Sector, which takes care of physical fitness and injuries associated with musculoskeletal.

[covid-safer-hotties]

Mild Primary or Breakthrough SARS-CoV-2 Infection Promotes Autoantibody Production in Individuals with and without Neuro-PASC - Published Aug 26, 2024

Abstract Patients with long COVID can develop humoral autoimmunity after severe acute SARS-CoV-2 infection. However, whether similar increases in autoantibody responses occur after mild infection and whether vaccination prior to SARS-CoV-2 breakthrough infection can limit autoantibody responses is unknown. In this study, we demonstrate that mild SARS-CoV-2 infection increases autoantibodies associated with rheumatic autoimmune diseases and diabetes in most individuals, regardless of vaccination status prior to infection. However, patients with long COVID and persistent neurologic and fatigue symptoms (neuro-PASC) have substantially higher autoantibody responses than convalescent control subjects at an average of 8 mo postinfection. Furthermore, high titers of systemic lupus erythematosus– and CNS-associated autoantibodies in patients with neuro-PASC are associated with impaired cognitive performance and greater symptom severity. In summary, we found that mild SARS-CoV-2 primary and breakthrough infections can induce persistent humoral autoimmunity in both patients with neuro-PASC and healthy COVID convalescents, suggesting that a reappraisal of mitigation strategies against SARS-CoV-2 is warranted to prevent transmission and potential development of autoimmunity.

[wheelie-sick]

What is immunocompromisation?

Being immunocompromised means you have a weaker immune system than most people. There are two main ways people become immunocompromised

1. Medical Conditions

Certain medical conditions cause your immune system to be weaker. Some examples include:

Immunodeficiencies- A category of conditions causing a lower number of or lower efficacy of immune cells. This category is divided into two subcategories: primary immunodeficiency and secondary immunodeficiency. Primary immunodeficiency is a subcategory consisting of hundreds of different conditions all causing a lower number of immune cells. Secondary immunodeficiency is a smaller category consisting of conditions where a person lacks immune cells due to other causes such as malnutrition.

HIV/AIDS

Some cancers

2. Medications

There are two main types of medications that result in being immunocompromised: Immunosuppressants and chemotherapy

Immunosuppressive medications- Immunosuppressive medications are medications designed to suppress your immune response. These can work in many different ways with some targeting a broad range of immune cells and others being highly specific. These medications are often used for organ transplant recipients and people with moderate-severe autoimmune diseases. Some medications in this category include: organ transplant medications, biologics, and high dose corticosteroids

Chemotherapy- Chemotherapy often comes with the effect of preventing new fast-dividing cells from being produced. This is why hair loss is such a common side effect of chemotherapy. Immune cells are fast dividing and therefore frequently are unable to be produced while on chemotherapy

The effects of immunocompromisation

Immunocompromisation has a large range of effects depending on the reason someone is immunocompromised. The most common effects are an increased susceptibility to illness and cancers. Increased susceptibility to illness can look like:

Frequent illnesses

Illnesses that are more severe than they would be for other people

Recurrent infections

Infections that don't respond to medication

Delayed response to infection

Infections that last longer than usual

Some people are more susceptible to certain types of infections. For example anifrolumab, a biologic used for lupus, makes people more susceptible to herpes zoster and respiratory tract infections while prednisone, a corticosteroid, increases risk of infection across the board. This occurs due to different causes of immunocompromisation affecting different immune cells with different roles in preventing and responding to infection.

Grades of severity

Recently the term "moderately and severely immunocompromised" has been used in covid-19 resources. Certain factors are considered to make someone moderately or severely immunocompromised, these include:

Advanced or untreated HIV infection

Moderate or severe primary immunodeficiencies

Hematologic malignancies

Active treatment for solid tumors or hematologic malignancies

Immunosuppressant medications used for solid organ or islet transplants

CAR-T cell therapy or hematopoietic stem cell transplantation

Treatment with alkylating agents, antimetabolites, high-dose corticosteroids, chemotherapeutic agents, TNF blockers, and other biologic agents that are immunosuppressive or immunomodulatory

What immunocompromisation is not

It's worth noting that getting sick frequently or getting seriously sick from illnesses that are usually mild is a warning sign for being immunocompromised but does not inherently make you immunocompromised. Some people are just more susceptible to illness without being immunocompromised.

Having minimal response to an infection that is usually more serious is a sign of a strong immune system, not a weak one.

Being immunocompromised is also not the same as being high risk for serious infection. All immunocompromised people are high risk but not all high risk people are immunocompromised. Immunocompromisation is specifically when someone is high risk because their immune system is weak. Particularly in regards to covid, there are many conditions that make you higher risk that do not involve a weak immune system.

Autoimmune diseases do not automatically make you immunocompromised. Something being a disorder of the immune system does not mean that you are immunocompromised because immunocompromised means a weaker immune system not a malfunctioning immune system.

[soath]

Apropos of absolutely nothing at all, oral and throat cancers from HPV don’t only occur in guys; anyone who engages in oral sex should be on the lookout for them! Symptoms include sudden loss of taste, swelling, numbness, a persistent sore throat, and pain. HPV can also cause cancers of the phallus, vulva, and anus. Because it’s a viral related cancer it can be especially dangerous for those with immune conditions, including HIV or some autoimmune diseases treated with immunosuppressants.

However the HPV vaccine is effective at preventing all of these cancers. In countries with high uptake many forms of cervical cancers have vanished among young people. The vaccine is most effective for younger children between 10-13 so if you have kids, siblings, nieces or nephews, push for them to get it! It’s also now recommended for adults up to middle aged. Even if you’ve already contracted one HPV strain, the vaccine may still be helpful. Although there’s increasing evidence of efficacy at just one dose, it’s most effective if you get all three in the series so don’t wait.

And if you’re eligible for Pap smears, get them. They might not be comfortable but they are one of the most effective medical tests invented in the twentieth century.

[eatclean-bewhole]

Truth is, our gut, skin, hormones, and cell health is better off without dairy.

#health #autoimmune #autoimmunedisease #antiinflammatory #guthealth #immunity #immunesystem #immunesupport #immunebooster #immuneboosting #dairyfree #dairy #healthtips #chronicillness #diseasemanagement #fibromyalgia #hashimotos #hyperthyroidism #hyperthyroidism #gravesdisease #lupus #rheumatoidarthritis #MS #wellness #diet #nutrition #integrativenutrition #chronicpain #nutritionist #integrativemedicine

[allthecanadianpolitics]

Islanders living with Type 1 diabetes are eligible to receive help with the cost of insulin pumps and related supplies beginning Sept. 1. The PEI Insulin Pump Program provides financial assistance to medically eligible residents, according to a news release from the province. The program was previously open to those up to age 25, however the province has now removed that age limit. [...] The province says there are approximately 1,100 people on Prince Edward Island who are living with Type 1 diabetes, which is an autoimmune disease that prevents the pancreas from producing insulin.

Continue Reading

Tagging: @newsfromstolenland

[mindblowingscience]

Two doses of allergen-encapsulating nanoparticles delivered intravenously prevented anaphylaxis during a food allergy test in mice, according to a study led by University of Michigan researchers. The results, published in Advanced Healthcare Materials, offer a potential path to improving the ease of allergy immunotherapies in humans which currently require daily doses of the allergen. In addition to the research in mice, this allergen-encapsulating nanoparticle platform has completed a Phase II clinical trial for treating the autoimmune condition celiac disease.

Continue Reading.