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#university of Florida
fuckingflorida · 2 months
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Link to tweet bc I don’t pay for that shit to download the video. According to comments on the tampabaysds IG the sheriff’s office has been hanging up on people who call but the most recent comments have said to keep calling (as of last night). I can’t find any more info on UF currently but will post if I do!
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reasonsforhope · 1 month
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"In a first-ever human clinical trial, an mRNA cancer vaccine developed at the University of Florida successfully reprogrammed patients’ immune systems to fiercely attack glioblastoma, the most aggressive and lethal brain tumor.
The results in four adult patients mirrored those in 10 pet dog patients suffering from brain tumors whose owners approved of their participation.
The discovery represents a potential new way to recruit the immune system to fight treatment-resistant cancers using an iteration of mRNA technology and lipid nanoparticles, similar to COVID-19 vaccines, but with two key differences: use of a patient’s own tumor cells to create a personalized vaccine, and a newly engineered complex delivery mechanism within the vaccine.
“Instead of us injecting single particles, we’re injecting clusters of particles that are wrapping around each other like onions,” said senior author Elias Sayour, M.D., Ph.D., a UF Health pediatric oncologist who pioneered the new vaccine, which like other immunotherapies attempts to “educate” the immune system that a tumor is foreign.
“These clusters alert the immune system in a much more profound way than single particles would.”
Among the most impressive findings was how quickly the new method spurred a vigorous immune-system response to reject the tumor, said Sayour, principal investigator at the University’s RNA Engineering Laboratory and McKnight Brain Institute investigator who led the multi-institution research team.
“In less than 48 hours, we could see these tumors shifting from what we refer to as ‘cold’—very few immune cells, very silenced immune response—to ‘hot,’ very active immune response,” he said.
“That was very surprising given how quick this happened, and what that told us is we were able to activate the early part of the immune system very rapidly against these cancers, and that’s critical to unlock the later effects of the immune response,” he explained in a video (below).
Glioblastoma is among the most devastating diagnoses, with median survival around 15 months. Current standard of care involves surgery, radiation and some combination of chemotherapy.
The new report, published May 1 in the journal Cell, is the culmination of seven years of promising studies, starting in preclinical mouse models.
In the cohort of four patients, genetic material called RNA was extracted from each patient’s own surgically removed tumor, and then messenger RNA (mRNA)—the blueprint of what is inside every cell, including tumor cells—was amplified and wrapped in the newly designed high-tech packaging of biocompatible lipid nanoparticles, to make tumor cells “look” like a dangerous virus when reinjected into the bloodstream to prompt an immune-system response.
The vaccine was personalized to each patient with a goal of getting the most out of their unique immune system...
While too early in the trial to assess the clinical effects of the vaccine, the patients either lived disease-free longer than expected or survived longer than expected. The 10 pet dogs lived a median of 4.5 months, compared with a median survival of 30-60 days typical for dogs with the condition.
The next step, with support from the Food and Drug Administration and the CureSearch for Children’s Cancer foundation, will be an expanded Phase I clinical trial to include up to 24 adult and pediatric patients to validate the findings. Once an optimal and safe dose is confirmed, an estimated 25 children would participate in Phase 2."
-via Good News Network, May 11, 2024
youtube
-video via University of Florida Health, May 1, 2024
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ncaapeaches · 7 days
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kayleebluffstone on Instagram
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athleticperfection1 · 2 months
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Florida Cheer
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hurricaneriley · 2 months
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howdy from the swamp
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beatrack92 · 1 month
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Parker Valby (Florida)
2022 SEC Cross Country Championships (Ole Miss)
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https://www.wsj.com/articles/the-adults-are-still-in-charge-at-the-university-of-florida-israel-protests-tents-sasse-eca6389b
The Adults Are Still in Charge at the University of Florida
By: Ben Sasse
Published: May 3, 2024
Higher education isn’t daycare. Here are the rules we follow on free speech and public protests.
Gainesville, Fla.
Higher education has for years faced a slow-burning crisis of public trust. Mob rule at some of America’s most prestigious universities in recent weeks has thrown gasoline on the fire. Pro-Hamas agitators have fought police, barricaded themselves in university buildings, shut down classes, forced commencement cancellations, and physically impeded Jewish students from attending lectures.
Parents are rightly furious at the asinine entitlement of these activists and the embarrassing timidity of many college administrators. One parent put it bluntly: “Why the hell should anybody spend their money to send their kid to college?” Employers watching this fiasco are asking the same question.
At the University of Florida, we tell parents and future employers: We’re not perfect, but the adults are still in charge. Our response to threats to build encampments is driven by three basic truths.
First, universities must distinguish between speech and action. Speech is central to education. We’re in the business of discovering knowledge and then passing it, both newly learned and time-tested, to the next generation. To do that, we need to foster an environment of free thought in which ideas can be picked apart and put back together, again and again. The heckler gets no veto. The best arguments deserve the best counterarguments.
To cherish the First Amendment rights of speech and assembly, we draw a hard line at unlawful action. Speech isn’t violence. Silence isn’t violence. Violence is violence. Just as we have an obligation to protect speech, we have an obligation to keep our students safe. Throwing fists, storming buildings, vandalizing property, spitting on cops and hijacking a university aren’t speech.
Second, universities must say what they mean and then do what they say. Empty threats make everything worse. Any parent who has endured a 2-year-old’s tantrum gets this. You can’t say, “Don’t make me come up there” if you aren’t willing to walk up the stairs and enforce the rules. You don’t make a threat until you’ve decided to follow through if necessary. In the same way, universities make things worse with halfhearted appeals to abide by existing policies and then immediately negotiating with 20-year-old toddlers.
Appeasing mobs emboldens agitators elsewhere. Moving classes online is a retreat that penalizes students and rewards protesters. Participating in live-streamed struggle sessions doesn’t promote honest, good-faith discussion. Universities need to be strong defenders of the entire community, including students in the library on the eve of an exam, and stewards of our fundamental educational mission.
Actions have consequences. At the University of Florida, we have repeatedly, patiently explained two things to protesters: We will always defend your rights to free speech and free assembly—but if you cross the line on clearly prohibited activities, you will be thrown off campus and suspended. In Gainesville, that means a three-year prohibition from campus. That’s serious. We said it. We meant it. We enforced it. We wish we didn’t have to, but the students weighed the costs, made their decisions, and will own the consequences as adults. We’re a university, not a daycare. We don’t coddle emotions, we wrestle with ideas.
Third, universities need to recommit themselves to real education. Rather than engage a wide range of ideas with curiosity and intellectual humility, many academic disciplines have capitulated to a dogmatic view of identity politics. Students are taught to divide the world into immutable categories of oppressors and oppressed, and to make sweeping judgements accordingly. With little regard for historical complexity, personal agency or individual dignity, much of what passes for sophisticated thought is quasireligious fanaticism.
The results are now on full display. Students steeped in this dogma chant violent slogans like “by any means necessary.” Any? Paraglider memes have replaced Che Guevara T-shirts. But which paragliders—the savages who raped teenage girls at a concert? “From the river to the sea.” Which river? Which sea?
Young men and women with little grasp of geography or history—even recent events like the Palestinians’ rejection of President Clinton’s offer of a two-state solution—wade into geopolitics with bumper-sticker slogans they don’t understand. For a lonely subset of the anxious generation, these protest camps can become a place to find a rare taste of community. This is their stage to role-play revolution. Posting about your “allergen-free” tent on the quad is a lot easier than doing real work to uplift the downtrodden.
Universities have an obligation to combat this ignorance with rigorous teaching. Life-changing education explores alternatives, teaches the messiness of history, and questions every truth claim. Knowledge depends on healthy self-doubt and a humble willingness to question self-certainties. This is a complicated world because fallen humans are complicated. Universities must prepare their students for the reality beyond campus, where 330 million of their fellow citizens will disagree over important and divisive subjects.
The insurrectionists who storm administration buildings, the antisemites who punch Jews, and the entitled activists who seek attention aren’t persuading anyone. Nor are they appealing to anyone’s better angels. Their tactics are naked threats to the mission of higher education.
Teachers ought to be ushering students into the world of argument and persuasion. Minds are changed by reason, not force. Progress depends on those who do the soulful, patient work of inspiring intellects. Martin Luther King Jr., America’s greatest philosopher, countered the nation’s original sin of racism by sharpening the best arguments across millennia. To win hearts, he offered hope that love could overcome injustice.
King’s approach couldn’t be more different from the abhorrent violence and destruction on display across the country’s campuses. He showed us a way protest can persuade rather than intimidate. We ought to model that for our students. We do that by recommitting to the fundamentals of free speech, consequences and genuine education. Americans get this. We want to believe in the power of education as a way to elevate human dignity. It’s time for universities to do their jobs again.
Mr. Sasse is president of the University of Florida.
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This is the way.
Never forget that the "speech is violence" people have spent the last few weeks trying to gaslight everyone that their violence is just protected speech.
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University of Florida engineers have developed a method for 3D printing called vapor-induced phase-separation 3D printing, or VIPS-3DP, to create single-material as well as multi-material objects. The discovery has the potential to advance the world of additive manufacturing. Yong Huang, Ph. D., a professor in UF's department of mechanical and aerospace engineering, said the printing process he and colleagues developed allows manufacturers to create custom-made objects economically and sustainably. The novel approach was reported Tuesday in the journal Nature Communications. "It is more economical and much simpler than current counterpart technologies," he said. "It's an affordable process for printing advanced materials, including metals."
Read more.
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opendirectories · 6 months
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courtneycantstudy · 8 months
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37-39/100 DOP (mon. oct. 16 - wed. oct. 18)
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i meant to post last night but i was in the library for a total of 10 hours yesterday on top of having a math exam… so… yeah.
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anyways, big update!!
chaarg has been going great, school has been bearable, and my family came to visit this past weekend :)
in even more exciting news:
I GOT MY ACCEPTANCE LETTER TO UF!!
i am over the moon about it and it still doesn’t seem real, but i am now beginning my preparations to transfer there next semester! :D
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🎧: beers and sunshine - darius rucker
📝: meliorism (n.): the belief that the world gets better; the belief that humans can improve the world
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earthanthem · 10 months
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(via GIPHY)
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ncaapeaches · 3 months
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ellielazzari10 on Instagram
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kp777 · 4 months
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University of Florida terminating all diversity, equity and inclusion positions
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athleticperfection1 · 6 months
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Florida Dancer
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hurricaneriley · 2 months
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nights out in gainesville
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