#Responsible Data Science
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codecrafted · 4 days ago
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10 Biggest Data Science Trends to Watch in 2025 Data science is evolving faster than ever! From generative AI and real-time analytics to edge computing and ethical AI, 2025 is set to bring groundbreaking changes. 🌐💡
Whether you're a data enthusiast, professional, or just curious, this list breaks down the biggest trends reshaping how businesses and tech teams work with data. Learn about synthetic data, low-code tools, quantum computing’s potential, and more.
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bethanydelleman · 2 years ago
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Hi! (Please ignore my question if it doesn't make sense) I saw in your bio that, in addition to being a Jane Austen fan, you are a cognitive neuroscientist. Do you have thoughts on any of her six major novels from a cognitive neuroscience perspective?
I have basically one thought: Louisa's fall in Lyme and the after-effects of her major traumatic brain injury are very realistic. Her symptoms, the recovery time, and the after effects are all textbook. Good work Jane Austen!
Otherwise, there isn't much neuroscience in Jane Austen's works. There may be some psychology, and I did learn quite a bit about abnormal psychology, but the very first thing we learned is that no one can be diagnosed with anything without a proper clinical interview and diagnostic tools. Not 200 year old book characters, not even a major political figure. Which is why I pretty much refuse to "diagnose" anyone with anything.
What my education does give me is a very data driven approach to the world. Jane Austen can be tricky because of free-indirect discourse and a very sarcastic narrator, but if you can support something with quotations, I'll accept it. For example, many people deny that Darcy wanted Georgiana to marry Bingley, despite there being an actual quote in the book that says that. I looked at the quote, I looked at all the surrounding evidence, I checked for sarcasm (the narrator mocks Darcy for thinking he could be unbiased, that's the sarcastic part), and then I concluded that it was supported by the text. To me, any other conclusion would be nothing but bias (the bias here being that the Bingleys are so trade-scummy that Darcy would never consider marriage to that family).
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cidthecoatrack-blog · 1 year ago
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Y'all, the world is sleeping on what NASA just pulled off with Voyager 1
The probe has been sending gibberish science data back to Earth, and scientists feared it was just the probe finally dying. You know, after working for 50 GODDAMN YEARS and LEAVING THE GODDAMN SOLAR SYSTEM and STILL CHURNING OUT GODDAMN DATA.
So they analyzed the gibberish and realized that in it was a total readout of EVERYTHING ON THE PROBE. Data, the programming, hardware specs and status, everything. They realized that one of the chips was malfunctioning.
So what do you do when your probe is 22 Billion km away and needs a fix? Why, you just REPROGRAM THAT ENTIRE GODDAMN THING. Told it to avoid the bad chip, store the data elsewhere.
Sent the new code on April 18th. Got a response on April 20th - yeah, it's so far away that it took that long just to transmit.
And the probe is working again.
From a programmer's perspective, that may be the most fucking impressive thing I have ever heard.
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jcmarchi · 6 months ago
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Turning adversity into opportunity
New Post has been published on https://thedigitalinsider.com/turning-adversity-into-opportunity/
Turning adversity into opportunity
Sujood Eldouma always knew she loved math; she just didn’t know how to use it for good in the world. 
But after a personal and educational journey that took her from Sudan to Cairo to London, all while leveraging MIT Open Learning’s online educational resources, she finally knows the answer: data science.
An early love of data
Eldouma grew up in Omdurman, Sudan, with her parents and siblings. She always had an affinity for STEM subjects, and at the University of Khartoum she majored in electrical and electronic engineering with a focus in control and instrumentation engineering.
In her second year at university, Eldouma struggled with her first coding courses in C++ and C#, which are general-purpose programming languages. When a teaching assistant introduced Eldouma and her classmates to MIT OpenCourseWare for additional support, she promptly worked through OpenCourseWare’s C++ and C courses in tandem with her in-person classes. This began Eldouma’s ongoing connection with the open educational resources available through MIT Open Learning.
OpenCourseWare, part of MIT Open Learning, offers a free collection of materials from thousands of MIT courses, spanning the entire curriculum. To date, Eldouma has explored over 20 OpenCourseWare courses, and she says it is a resource she returns to regularly.
Play video
Sujood from Sudan: An Open Learner’s Story Video: MIT OpenCourseWare
“We started watching the videos and reading the materials, and it made our lives easier,” says Eldouma. “I took many OpenCourseWare courses in parallel with my classes throughout my undergrad, because we still did the same material. OpenCourseWare courses are structured differently and have different resources and textbooks, but at the end of the day it’s the same content.”
For her graduation thesis, Eldouma did a project on disaster response and management in complex contexts, because at the time, Sudan was suffering from heavy floods and the country had limited resources to respond.
“That’s when I realized I really love data, and I wanted to explore that more,” she says.
While Eldouma loves math, she always wanted to find ways to use it for good. Through the early exposure to data science and statistical methods at her university, she saw how data science leverages math for real-world impact.
After graduation, she took a job at the DAL Group, the largest Sudanese conglomerate, where she helped to incorporate data science and new technologies to automate processes within the company. When civil war erupted in Sudan in April 2023, life as Eldouma knew it was turned upside down, and her family was forced to make the difficult choice to relocate to Egypt.
Purpose in adversity
Soon after relocating to Egypt, Eldouma lost her job and found herself struggling to find purpose in the life circumstances she had been handed. Due to visa restrictions, challenges getting right-to-work permits, and a complicated employment market in Egypt, she was also unable to find a new job.
“I was sort of in a depressive episode, because of all that was happening,” she reflects. “It just hit me that I lost everything that I know, everything that I love. I’m in a new country. I need to start from scratch.”
Around this time, a friend who knew Eldouma was curious about data science sent her the link to apply to the MIT Emerging Talent Certificate in Data and Computer Science. With less than 24 hours before the application deadline, Eldouma hit “Submit.”
Finding community and joy through learning
Part of MIT Open Learning, MIT Emerging Talent at the MIT Jameel World Education Lab (J-WEL) develops global education programs that target the needs of talented individuals from challenging economic and social circumstances by equipping them with the knowledge and tools to advance their education and careers.
The Certificate in Computer and Data Science is a year-long online learning program that follows an agile continuous education model. It incorporates computer science and data analysis coursework from MITx, professional skill building, experiential learning, apprenticeship options, and opportunities for networking with MIT’s global community. The program is targeted toward refugees, migrants, and first-generation low-income students from historically marginalized backgrounds and underserved communities worldwide.
Although Eldouma had used data science in her role at the DAL Group, she was happy to have a proper introduction to the field and to find joy in learning again. She also found community, support, and inspiration from her classmates who were connected to each other not just by their academic pursuits, but by their shared life challenges. The cohort of 100 students stayed in close contact through the program, both for casual conversation and for group work.
“In the final step of the Emerging Talent program, learners apply their computer and data knowledge in an experiential learning opportunity,” says Megan Mitchell, associate director for Pathways for Talent and acting director of J-WEL. “The experiential learning opportunity takes the form of an internship, apprenticeship, or an independent or collaborative project, and allows students to apply their knowledge in real-world settings and build practical skills.”
Determined to apply her newly acquired knowledge in a meaningful way, Eldouma and fellow displaced Sudanese classmates designed a project to help solve a problem in their home country. The group identified access to education as a major problem facing Sudanese people, with schooling disrupted due to the conflict. Focusing on the higher education audience, the group partnered with community platform Nas Al Sudan to create a centralized database where students can search for scholarships and other opportunities to continue their education.
Eldouma completed the MIT Emerging Talent program in June 2024 with a clear vision to pursue a career in data science, and the confidence to achieve that goal. In fact, she had already taken the steps to get there: halfway through the certificate program, she applied and was accepted to the MITx MicroMasters program in Statistics and Data Science at Open Learning and the London School of Economics (LSE) Masters of Science in Data Science.
In January 2024, Eldouma started the MicroMasters program with 12 of her Emerging Talent peers. While the MIT Emerging Talent program is focused on undergraduate-level, introductory computer and data science material, the MicroMasters program in Statistics and Data Science is graduate-level learning. MicroMasters programs are a series of courses that provide deep learning in a specific career field, and learners that successfully earn the credential may receive academic credit to universities around the world. This makes the credential a pathway to over 50 master’s degree programs and other advanced degrees, including at MIT. Eldouma believes that her experience in the MicroMasters courses prepared her well for the expectations of the LSE program.
After finishing the MicroMasters and LSE programs, Eldouma aspires to a career using data science to better understand what is happening on the African continent from an economic and social point of view. She hopes to contribute to solutions to conflicts across the region. And, someday, she hopes to move back to Sudan.
“My family’s roots are there. I have memories there,” she says. “I miss walking in the street and the background noise is the same language that I am thinking in. I don’t think I will ever find that in any place like Sudan.”
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eimearkuopio · 9 months ago
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Chromebook Linux is a fucking nightmare anyway. In my last job I always ended up spending several hours helping at least a few students who only had Chromebooks install the tools we needed for them to be able to do their coursework. My current job involves teaching in a STEM department and Chromebooks aren't acceptable computers for the students, not as a form of gatekeeping but because we just can't help 200 students from non-STEM backgrounds figure out how to keep their packages up to date.
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stuffforthestash · 1 year ago
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I saw a post about tumblr user ages...
Reblogs are welcomed for that sweet, sweet increased data pool (aka getting more than 20 responses 😅)
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21st-century-minutiae · 2 years ago
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Survey selection bias is a common problem in early twenty-first century demographic analysis. It is well understood and accounted for (as much as possible) by competent statisticians. Any good faith demographer will include a methodology section in their report that should help identify potential sources of bias, and savvy individuals will use this information to properly interpret the data. For example, low sample sizes, restricting surveys to students at a particular college (who might be answering the questions for class credit or money), or (as listed above) telephone surveys can lead to nuances in the results.
However, laymen might lack the knowledge to account for these nuances. This can be exacerbated when media reports on the results, but fails to include the methodology (this is actually a good judgement of media impartiality and accuracy: if they include the survey size when reporting or other methodology details, especially in graphics, that is a good sign. If they omit it, that is a bad sign). People also are very prone to report simple summaries, such as final percentages, without including methodology detail, which leads to the spread of misinformation.
One extremely famous example of methodology bias was in the 1948 US Presidential Election. Based on confident polling data, the Chicago Tribune printed a newspaper headline "Dewey Beats Truman" when, in fact, Truman had won. The polls were all flawed in methodology, often directly polling individuals on a street corner where they could find people instead of stochastically selecting individuals from the entire population. There is a famous picture of Truman holding up this particular newspaper headline in triumph. Many people in the early twenty-first century are aware of this picture, as it has had a substantial cultural impact.
Let's consider the sampling bias of a classic polling method: the telephone survey.
In many jurisdictions, robo-calling cell phone numbers is illegal, so right off the jump, our sample is limited to people with landlines.
Second, our survey's calling centre probably doesn't operate 24/7, and you can only answer a home landline when you're at home, so we're also selecting for people who tend to be at home during our calling centre's office hours.
Third, most people who have landlines probably also have answering services and caller ID, so we're additionally selecting for people who answer unknown numbers rather than letting them go to the machine.
Fourth, our recipient needs to be able to participate in the survey, so we're also selecting for people who speak the language(s) in which the survey is being administered.
Finally, after all this, most people will just hang up once they figure out they're being polled, so in sum, we're selecting for people who:
have landlines;
are usually at home during our calling centre's office hours;
customarily answer unknown numbers;
speak the language(s) in which the survey is administered; and
are actually interested in responding to surveys.
Any one of these factors is likely to introduce very serious bias into our results; all of them taken together are going to render our data practically meaningless for most purposes.
Now, understand that this still represents less selection bias than trying to do demographic surveys by reblogging Tumblr polls.
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wutheringheightsfilm · 7 months ago
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for everyone asking me "what do we do??!??!"
The Care We Dream Of: Liberatory and Transformative Approaches to LGBTQ+ Health by Zena Sharman
Mutual Aid: Building Solidarity During This Crisis (And the Next) by Dean Spade
Cop Watch 101 - Training Guide
The Do-It Yourself Occupation Guide
DIY HRT Wiki 
The Innocence Project - helps take inmates off of death row
Food Not Bombs 
Transfeminine Science - collection of articles and data about transfem HRT
Anti-Doxxing Guide for Activists
Mass Defense Program - National Lawyers Guild
How to be part of a CERT (Community Emergency Response Team)
Understanding and Advocating for Self Managed Abortion
The Basics of Organizing
Building Online Power
Build Your Own Solidarity Network
Organizing 101
How to Start a Non-Hierarchical Direct Action Group
A Short and Incomplete Guide for New Activists
Eight Things You Can Do to Get Active
Palestine Action Underground Manual
How to Blow Up a Pipeline by Andreas Malm
Spreadsheet of gynecologists that will tie your tubes without bothering you about it
COVID Resource Guide
Mask Bloc NJ (find one near you, these are international!)
Long Covid Justice
Donate to Palestinian campaigns (2, 3, 4)
Donate to Congolese campaigns (2, 3) 
Donate to Sudanese campaigns (2, 3)
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societyfolklore · 2 months ago
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Open Up Baby
Title: Open Up Baby Pairing: Tony Stark  x Female Reader
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Summary: Tony Stark straps you into a StarkTech-compatible bench for a private demonstration of his newest toys- complete with biometric feedback,
Word Count: 3.6k
Warnings:  / Explicit Content /18+, Minors DNI, SMUT… BDSM/Restraints/Bondage, custom tech ball gag, toys (Egg vibe, anal beads, dildo)  Overstimulation, Toy fucking/Machine-assisted thrusting, Filthy talk (Tony can't shut up), AI assists with data tracking, clinical observation, forced openness, Sensory overload
A/N: my entry for  @avengers-assemble-bingo  for April Kinky Bingo… Well this one turned into a whole thing.. Square: B2- Open Up Baby  Card Number: KB003
You were already strapped to the bench- back arched, thighs spread wide in glossy chrome stirrups, wrists bound snug in Stark-grade cuffs that didn’t budge an inch. The synthetic leather beneath you was cool against your skin, but your body was already starting to heat with anticipation. The bench itself shifted slightly with every movement, like it was reading your tension, calibrating every twitch of your muscles into data Tony could access later.
You could hear the soft hum of the room’s ambient systems, the low mechanical whirrs, the faint electric pulse of tech running in standby, and underneath it all, Tony’s voice. He hummed absently as he moved around you, flicking through translucent holoscreens that floated in the air, readable only to him. Light glinted off his arc reactor through the thin black shirt he wore, sleeves rolled up to his elbows, veins flexing with every subtle flick of his fingers.
He looked like a scientist. Or a surgeon. No, a goddamn artist.
“You look tense,” he murmured, stepping in close, his fingers grazing your jaw with a feather-light touch. “That won’t do. We need to get a clean read. No clenched teeth, no locked jaws. Just you- open and…relaxed.”
He held up a sleek piece of tech. A mix of leather and metal. To you it looked like a ball gag. That wasn’t just a gag. It was his gag. Something custom. Personal. Laced with Stark Industry Tech.
“Open up, baby. Gotta install the biometric reader. It’s not science without a baseline.”
You hesitated, lips twitching. Just for a second. But he didn’t push. He just waited you out, smirk deepening, one brow arched like he had all the time in the world. That cocky, knowing gaze made you squirm even before anything touched you. Your breath hitched. And then you parted your lips.
“There we go,” he said, tone thick with approval as he slid the gag into place. It clicked against your teeth, snug and firm. A soft vibration flickered across your tongue as it locked in pushing the muscle down.
Friday’s voice chimed in overhead, calm and clinical.
“Gag calibration complete. Biometric sync active. Tracking vocal response, saliva levels, and tongue pressure.”
Tony leaned down, brushing his lips across your cheek in a whisper of a kiss. “Good girl. Now let’s get to work.”
He started with the egg.
Sleek. Silver. Pulsing faintly in his hand like it had a heartbeat of its own. The metal shimmered under the clinical lights, smooth and polished, shaped with the kind of precision that only Stark could deliver. He turned it over once, twice, like he was admiring a prized gadget- one that he was particularly proud of.
He showed it to you like a doctor unveiling a revolutionary new tool- calm, confident, deeply amused. Except this wasn’t a sterile exam room, and the look in his eyes wasn’t professional. His smirk told you he already knew what kind of mess this thing would reduce you to.
"This is your warm-up," he said, voice low and playful. "Phase One. Internal warming protocol. Testing receptivity. Calibration through heat and pulse response."
You whimpered into the gag. Of course you were excited- he’d been teasing you with this little 'demonstration' all week. Whispering promises in your ear, tapping out reminders on your thigh, dropping technical jargon laced with filth that left your core throbbing before he’d even touched you. Now that it was finally happening, your whole body was buzzing with need.
He didn't wait. He moved closer, one gloved hand parting your thighs a little further, the other settling between them. The bench adjusted beneath you, lifting your hips another inch to meet his touch perfectly. His fingers dipped between your folds- testing your wetness, teasing you just enough to make your body jerk in its bonds.
"Already responsive," he muttered, half to himself, half to Friday. "She’s going to be a dream to log."
He slid the egg in with two fingers, slow and deliberate. The cool metal kissed your entrance, making you flinch slightly- it was colder than you expected, stark contrast against your heated skin. Your walls instinctively tried to resist, clenching down, but his fingers were patient, coaxing you open, parting you around the sleek, unyielding toy.
The egg slid upward, heavy and smooth. As it moved deeper, your body yielded to it, the slow stretch making your breath catch. Its contours were designed to press into every sensitive spot, and you could feel your muscles fluttering around it, trying to accommodate the sudden fullness. As he pushed it deeper, you could feel every inch of it being swallowed by your body, your slick muscles tightening, fluttering around the intrusion.
He pushed the egg up high inside you, then paused, his finger still inside you too. "Squeeze for me," he ordered. You did, instinctively, your walls closing down as you used your pelvic floor, and Tony gave the platic string attached a soft tug.
The stretch, the resistance- it was delicious. The egg stayed locked in place. You couldn’t push it out if you tried. He smiled, clearly pleased.
"Perfect. Secure fit," he murmured. "Wouldn’t want it popping out mid-test."
It settled deep inside you, a sinful throb blooming in your core. Then it pulsed- just once, a quick flutter that made you jolt.
"There we go," he breathed, watching the screen light up with new data. "Didn’t even turn it on yet and she’s already going. Fuck, I love this job."
You were barely processing the first toy when he reached for the second.
Beads. Tapered, growing in size, each one gleamed under the soft blue lighting like tiny pieces of futuristic art. You squirmed, thighs pressing together, but it was no use- Stark had seen your reaction.
Tony laughed- low and delighted.
"Didn’t know we were going there, huh?" He nudged your knees apart again, voice dipping to a darker octave. "Come on, baby. I want you to open up for me. Let’s see what this one does..."
You shook your head slightly. Whimpered into the gag. Wide eyes watching him as you tried to protest around the ball gag in your mouth. 
Tony turned to the tray beside him, selecting a small, frost-blue tube of gel. "Wouldn't be very considerate to skip prep," he muttered, more to himself than to you. He uncapped the tube and squeezed a slow, deliberate line of the slick, glistening substance along the length of the beads. The gel shimmered faintly under the light, warming as it reacted with the ambient temperature.
He coated each bead carefully, fingers moving with methodical ease, making sure the entire string was evenly slicked. "Lubricated. Body-safe. Custom formula," he said with a wink. "Slippery enough to slide in smooth- sticky enough to stay in place until I say otherwise."
Then he held the beads up for you to see, the string dangling between his fingers. You tensed instinctively.
"Oh no. You’re freezing up. Can’t test properly if you don’t behave. Legs. Open."
You didn’t.
Tony tsked, clicking his tongue in mock disappointment. Then he grabbed your chin, firm and steady, tilting your head so your eyes locked with his.
"Don't think so much. That’s not what good test subjects do."
Click.
The bench tilted beneath you without warning. Your hips rolled upward, knees falling further apart as the restraints auto-adjusted. You were fully exposed now- helpless. Wide open.
"You know I can override those restraints, right? I built them. Now be a good girl and show me everything."
He dipped his finger back into the gel and brought it to your ass, pressing a cool dollop directly to your tight, puckered entrance. The sudden chill made you flinch, but it was followed by the warm glide of his fingertip as he gently teased the gel in slow circles.
"You tense here, too," he said, amused. "Don't worry. This formula warms up just like you do."
He rubbed it in carefully, working the gel into your rim with delicate, coaxing pressure. The sensation tingled- both from the temperature shift and the way his finger circled and pressed until your body finally began to relent.
Then he lowered the beads between your cheeks and began to press them in- one at a time. The first slid in easily, the gel working its magic, cool and slick. The second made your breath stutter. The third had your whole body tensing as your hole stretched just enough to accommodate the new pressure.
Each one pulled a different, desperate noise from you- somewhere between a gasp and a whimper, caught in the back of your throat and forced through the gag in broken fragments.
By the time the third bead settled inside you, you felt full. Stretched in ways that left you panting, your back arching hard off the bench. Everything was working together- the deep pressure of the egg nestled high in your core, the hum beginning to buzz through your clit like a phantom, and now the slow, firm intrusion of the beads pressing against nerves that had you seeing stars. You struggled to catch your breath, the gag forcing each inhale to be short and choppy. Air hissed through your nose while your mouth flooded with saliva, spit slipping from the corners of your lips in thick strands that slid down your neck and onto your chest. The overwhelming heat of arousal and frustration tangled in your gut, building like steam with nowhere to escape. The restraint of it made the fire inside you burn hotter.
Your muscles clenched involuntarily, your hips rocking against the air, chasing friction that didn’t come. You couldn’t speak, couldn’t beg. Just drool, tremble, and take everything he gave you.
"Mmm. That moan? That was bead three. She likes that one, Friday."
"Confirmed," the AI replied. "Pelvic floor tension rising. Heart rate increasing."
"Good. Means it’s working."
The egg began to heat. The beads hummed in sync, and you felt everything shift- internally and externally- as pleasure bled into pressure, and pressure into overload. You were trembling now, thighs twitching again, trying to close- but the bench held you wide, utterly exposed.
"Heart rate’s spiking..." Tony’s voice was pure, filthy glee. "Oh, she’s gonna break soon. Look at her squirm."
You rutted against the air, clit untouched and screaming for attention. Your walls fluttered around the egg, your ass clenching down against the beads as the different pulses overlapped and collided. It was all too much and somehow not enough. You needed more and needed it to stop, all at once.
You tried to breathe, but the gag made it impossible to take anything but shallow, panting gasps. Each exhale was laced with a moan. Drool spilled freely down your chin, dripping warm across your face and neck. You were flushed, messy, wrecked- and he hadn’t even touched your clit.
Your back arched violently off the bench, cords of heat coiling through your belly and thighs. It felt like your body was unraveling, muscles tight and desperate, nerve endings screaming with pleasure.
Tony leaned in again, voice dark and syrup-smooth. "We’ve got her plugged, egged, and ready to combust. Think she can handle the next phase?"
Friday answered, "Orgasm build-up at 87%."
"Perfect." He tapped a command into the air. "Now let’s push her."
The egg pulsed deeper. The beads vibrated sharper. You cried out- moaning, writhing, the gag muffling it into raw, incoherent noise. You couldn’t form words. Couldn’t beg. Just sob through the pressure building to a breaking point.
"Baby, this is science. Filthy, beautiful science."
It hit you like a wave- white-hot and all-consuming. Your legs shook violently in the stirrups, muscles spasming as your body locked around the egg and beads pulsing inside you. Every nerve ending fired in chaotic pleasure, overwhelming your senses. You tried to scream, to sob, but the gag reduced it to a shattered, strangled cry that vibrated through the tech, each desperate noise dutifully logged.
Drool spilled in long, wet strands down your chin as your back bowed hard off the bench, your whole body trembling under the assault of pleasure. Your cunt clenched tight around the egg, milking it involuntarily, while your ass throbbed with each hum of the vibrating beads. Everything inside you was pulsing, moving, grinding you down into submission.
Tony watched, transfixed, his gaze locked on your ruined, shaking form. “There she goes - God, I should patent that moan.”
Your eyes rolled back. You could barely breathe. You could only tremble and leak and convulse as the orgasm tore through you. The bench beneath you vibrated subtly with your body’s response.
Friday: "Orgasm confirmed."
Tony waited until you were trembling, your breathing uneven, your thighs still twitching with aftershocks that rippled through your overstimulated body. Sweat slicked your skin in a thin, glistening sheen, catching the light as your chest heaved with broken gasps around the gag. Your limbs strained weakly against the restraints.
Then- slowly, methodically- he reached between your cheeks and took hold of the first bead. He didn’t rush. He eased it out one at a time, each slick orb dragging along your inner walls with a sticky, stretching glide. You shuddered at the sensation- the unbearable emptiness that bloomed in the wake of each removal. Your ass clenched reflexively around the loss, trying to hold onto what had filled you so completely. But he kept going.
The final bead popped free with a slick, obscene sound. Your hips jolted involuntarily, your back arching once more as your body spasmed again, clinging to the ghost of sensation.
Friday's voice crackled overhead. "Anal pressure reduced. Sphincter still contracting. She’s experiencing post-orgasmic muscle spasms."
Then came the egg.
He curled his fingers inside you, tugging the retrieval loop with a firm, practiced motion. The egg slipped free, wet and shiny,  your cunt fluttering uselessly around the sudden void. The stretch, the drag, the warmth- it all left you aching. You cried into the gag, overwhelmed by the emptiness and the continued tremors in your muscles. Your thighs kicked slightly, your knees drawing in as far as the restraints would allow.
"Vaginal walls contracting. Core temperature still elevated. She's not done trembling yet," Friday observed, calm as ever.
Tony held both toys in one hand now- wet, warm, shining. He looked down at you with naked satisfaction.
"That’s some damn good tech," he said. "But we’re not done."
From the tray, he lifted his final piece.
A dildo- sleek, deep grey, Stark-stamped at the base. Modeled after him, and you knew it. Maybe a little bigger. Slightly wider at the base, with delicate ridges along the underside that hinted at something extra. Your breath caught just looking at it.
“This one’s special, baby. Built it from memory- well, from yours,” Tony said, rolling it in his hand. “Temperature regulated, pressure-sensitive, and the best part? The internal sensors sync to your contractions. It responds to you. The more you clench, the deeper it drives. A perfect loop.”
You whimpered around the gag, heart fluttering.
He moved between your spread legs and lined it up against your soaked, fluttering entrance. You were already sensitive- still trembling from the last orgasm- and when the wide tip pressed in, you nearly cried. It stretched you slowly, steadily, a little more than you were used to. Your slick walls resisted at first, clenching down instinctively, but Tony was patient, guiding it with precise control.
“There you go,” he coaxed, voice smooth but sharp-edged with amusement. “That’s it. Take all of it. Come on, baby- I know you can..”
His tone dipped into a purr. “There you go. Taking it like you need it. Bet you love being filled up with Stark-grade tech, huh?”
Your back bowed off the bench as he pushed it in, inch by inch, your pussy yielding to every contour, forced to accommodate the full shape of it. The fullness was delious, your body stretched taut around it. Your eyes rolled back as the final ridge slipped inside, the toy settling deep.
“There,” he said, watching your reactions with fascination. “Fills you out just right. And now... we see what she can really do.”
The base clicked into a pulse pattern, and the toy began to move inside you- slow at first, deliberate, like it was learning your shape. You could feel every textured ridge of the shaft as it rubbed against your inner walls, dragging across oversensitive flesh, sparking little detonations of pleasure with every pass.
Then it pulsed- long and low, a rhythmic thrum that radiated from base to tip, sending heat spiraling through your belly. With every thrust, the toy seemed to stretch you deeper, nudging a spot that made your toes curl and your thighs twitch against the restraints. Your pussy clenched around it reflexively, triggering the internal sensors Tony had mentioned. And just like that, the toy responded- pressing harder, thrusting deeper, faster.
It wasn’t just fucking you- it was reading you, syncing to the wild flutter of your muscles, pulsing in tandem with your arousal.
“Look at her,” Tony murmured, grinning as he watched the toy disappear again and again between your legs. “Every little squeeze makes it work harder. You’re doing this to yourself, baby. And I haven’t even touched your clit yet.”
You’d been so consumed by the thrusting inside you, by the stretch and pulse of the toy, that you hadn’t even noticed Tony move. But suddenly, he was there- looming over you, and the egg was pressed directly to your clit.
The sensation was immediate and brutal.
Your entire body jolted. The contact felt almost painful, your nerves raw and exposed, the stimulation electric. You tried to buck away, hips arching, thighs trembling, but you had nowhere to go.
Tony caught you effortlessly. One hand shoved the egg against your swollen clit, refusing to relent, while the other pressed down on your thigh to keep your knees from closing.
“Uh uh. None of that,” he said smoothly. “You don’t get to hide from this, baby. You earned it.”
You sobbed into the gag, thrashing your hips side to side, but the bench and Tony’s hands made escape impossible. Every attempt to squirm just sent the dildo thrusting deeper inside you, and the egg grinding cruelly over your clit.
“You’re not gonna break,” he whispered, teasing. “You’re gonna burn for me.”
"Don’t you dare run from it. look at me."
He was holding you still- one hand clamped over your thigh to keep your legs spread, the other pressing the egg mercilessly to your clit. You were trembling in his grasp, utterly helpless against the merciless pairing of his tech and his control.
"You’re gonna come again for me, sweetheart. Real data’s in the repeat response," he said, eyes locked on yours, voice both commanding and hungry.
The dildo thrust deep, the ridges grinding against your most sensitive spots as your walls clamped down. The egg buzzed brutally against your swollen clit, so overstimulated you couldn’t tell whether you were trying to run from it or chase it. Every jolt of pleasure lit your nerves like lightning- white-hot and impossible to hold back.
Your body jerked, hips spasming, thighs trembling violently as the sensations overloaded you. Your entire body was working against you- every clench, every twitch, every gasp just triggered the toy to go deeper, harder, faster. You weren’t riding it anymore- it was riding you, and Tony just watched with that devilish smirk, keeping you wide open.
“That's it. Shake for me. Scream into that gag. Show me what science can do.”
The climax tore through you without mercy- harder, deeper, a violent unraveling of every nerve as your body convulsed around the relentless rhythm of the tech inside you. You didn’t just come; you shattered, splintering open in a release so intense it blurred your vision, your mind, your ability to distinguish pleasure from pain. Your vision shattered into sparks, your scream muffled into a raw, hoarse noise behind the gag. Your body thrashed in the restraints, muscles locking as the orgasm ripped through you, longer and sharper than the last.
Friday: "Second orgasm confirmed. Neural spike significant. Subject approaching physical limit."
He slowed the toy, letting it ease to a stop deep inside you before withdrawing it carefully, letting you feel every last ridge dragging along your raw, overstimulated walls. Then, with a gentleness that almost contrasted the torment he’d just put you through, he removed the egg from your clit. The instant the contact broke, your whole body sagged in the restraints with relief and exhaustion. You were shaking, barely breathing- every inch of you buzzing, nerves fried and twitching from the overload.
You could taste salt on your lips- your own tears and spit, your jaw aching from clenching around the gag. You were drenched, body glistening with sweat, your skin flushed and hypersensitive to the air.
He removed the gag last. Your jaw fell slack with a wet, trembling gasp, strands of spit clinging to the corners of your mouth. You blinked up at him, vision hazy, lips wet and parted.
Tony gazed down at you, eyes gleaming with wicked satisfaction, his mouth tugging into a crooked grin that said told you so. He looked like a man admiring his finest creation- smug, yes, but also thoroughly entertained by the glorious, twitching mess sprawled out beneath him.
“You did good, baby. Fucking beautiful. But next time?”
He leaned close, brushing a kiss to your temple- slow, deliberate, his breath warm against your damp skin.
“Think I’ll need to design something that gets you to squirt. Can’t let a variable like that go untested. Wouldn’t be very Stark of me to stop now, would it?”
He turned with a little flourish, tapping the screen with a flick of his fingers, not bothering to look back.
“Friday, save this session. Label it: Successful. Prepare files for Phase Two.”
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uthra-krish · 2 years ago
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Unveiling the Role and Responsibilities of a Data Scientists
Data science is a dynamic and integral field in today's data-driven world. At the forefront of this domain are data scientists, who play a pivotal role in collecting, analyzing, and interpreting vast sets of data to extract meaningful insights and drive informed choices. Their multifaceted roles and responsibilities are indispensable in various industries and sectors. In this comprehensive exploration, we will delve into the key responsibilities and contributions of data scientists, from data collection and preprocessing to machine learning, modeling, and effective communication of results. Additionally, we will emphasize the significance of continuous learning and research in this ever-evolving field. 
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Data Collection and Integration:
Data scientists are the foundation of data-driven decision-making. They are responsible for gathering data from a wide array of sources, which can encompass structured data from databases, unstructured data from social media, and semi-structured data. This involves not only the collection but also ensuring data quality and integration. Data scientists prepare data for analysis by ensuring it is complete, consistent, and compatible.
Data Cleaning and Preprocessing:
Data is rarely pristine and ready for analysis. Data scientists face the essential task of cleaning and preprocessing data. This process involves removing inconsistencies, dealing with missing values, and identifying and handling outliers. Clean data is the cornerstone of accurate analysis.
Exploratory Data Analysis (EDA):
Exploratory Data Analysis (EDA) is a crucial step in data analysis. During this phase, data scientists visualize and summarize data to identify patterns, correlations, and trends. They employ statistical tools and techniques to gain insights from the data, providing a foundation for subsequent analysis and decision-making.
Machine Learning and Modeling:
Machine learning and modeling are at the core of a data scientist's role. They build predictive models using machine learning algorithms, training models to make forecasts, classifications, and other data-driven decisions. Model selection, training, and evaluation are integral to this responsibility, requiring a deep understanding of various algorithms and techniques.
Feature Engineering:
To enhance model performance, data scientists engage in feature engineering. This process involves selecting and transforming variables (features) to improve model accuracy and prediction capability. Data scientists determine which features are relevant and construct new ones to enhance the overall performance of models.
Model Evaluation and Validation:
Creating models is just the beginning; data scientists must rigorously test and validate these models to ensure they generalize well to new data. They employ techniques such as cross-validation and various performance metrics to assess model accuracy and reliability. This ensures that the models are robust and perform as intended.
Deployment and Integration:
Data scientists collaborate with software engineers to deploy models into production environments. This often involves integrating models into software applications, databases, or other systems. This critical step ensures that the insights and predictions derived from data analysis are utilized effectively within an organization.
Communication of Results:
Effectively conveying findings and insights to non-technical stakeholders is a vital aspect of a data scientist's role. Data scientists must create data visualizations and reports that convey complex results in a comprehensible manner. Clear and concise communication is essential for guiding informed decision-making within an organization.
Domain Knowledge:
Data scientists operate in various industries and sectors, each with its unique context and challenges. To work effectively, they need domain expertise. They must understand the industry, business goals, and the specific context of the data they are analyzing. This domain knowledge enables data scientists to extract relevant insights and align their analyses with organizational objectives.
Continuous Learning and Research:
The field of data science is continually evolving. New tools, techniques, and research are constantly emerging. To remain at the forefront of the industry, data scientists must engage in continuous learning and research. Staying updated with the latest developments in data science is vital for maintaining proficiency and relevance in the field.
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In the rapidly expanding field of data science, professionals are in high demand. The role and responsibilities of a data scientist encompass a wide range of tasks, from data collection and preprocessing to machine learning, modeling, and effective communication of results. These professionals are essential for guiding data-driven decision-making within organizations. For those interested in pursuing a career in data science or enhancing their data analysis skills, ACTE Technologies offers comprehensive Data Science courses. ACTE Technologies equips individuals with the knowledge and hands-on experience needed to excel in this dynamic and data-driven field. By enrolling in ACTE Technologies' programs, individuals can gain a competitive edge and contribute effectively to the world of data science, helping organizations make data-informed decisions and drive success in an increasingly data-centric world.
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xaltius · 2 years ago
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Exploring the Promising Future Scope of Data Science
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Introduction
In today's data-driven world, the field of data science has emerged as a powerful force that drives innovation, decision-making, and problem-solving across various industries. As technology continues to advance and data becomes more abundant, the future scope of data science looks incredibly promising. In this blog, we'll delve into some exciting trends and potential avenues that highlight the vast opportunities awaiting data scientists in the years to come.
AI and Machine Learning Integration
Artificial Intelligence (AI) and Machine Learning (ML) are set to play an even more significant role in data science's future. As algorithms become more sophisticated and capable of handling complex tasks, businesses will increasingly rely on AI-powered solutions for predictive analysis, automation, and recommendation systems. AI will also enhance decision-making processes, making organizations more agile and responsive.
Advanced Analytics for Unstructured Data
Data science has traditionally focused on structured data. However, the future will bring an increased emphasis on unstructured data, such as text, images, audio, and video. Natural Language Processing (NLP) and Computer Vision will be essential tools for extracting insights from unstructured sources, enabling businesses to gain valuable information from a wider range of data types.
IoT and Edge Analytics
The Internet of Things (IoT) is poised to create an explosion of data generated by interconnected devices. Data scientists will have the task of harnessing this data to extract meaningful insights and drive actionable outcomes. Edge analytics, which involves processing data closer to its source, will become crucial in scenarios where real-time decision-making is required, such as autonomous vehicles and industrial automation.
Ethics and Responsible AI
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As data science continues to evolve, so do the ethical considerations associated with its applications. The responsible use of AI and data requires addressing issues of bias, privacy, transparency, and accountability. Data scientists of the future will need to incorporate ethical considerations into their work, ensuring that technology benefits society as a whole.
Personalized Healthcare
Healthcare stands to gain immensely from data science advancements. With the integration of electronic health records, wearables, and genomic data, medical professionals can make more accurate diagnoses and personalized treatment plans. Predictive analytics can help identify potential health risks in individuals, enabling proactive interventions.
Environmental Sustainability
Data science can contribute significantly to solving global challenges like climate change. By analyzing vast amounts of environmental data, scientists can model climate patterns, predict natural disasters, and develop strategies for resource conservation. Data-driven insights will empower policymakers and organizations to make informed decisions that promote sustainability.
Data Privacy and Security
The increasing reliance on data also brings about concerns regarding its security and privacy. Data breaches and cyberattacks can have severe consequences. The future of data science involves developing advanced encryption techniques, secure data sharing protocols, and robust authentication methods to protect sensitive information.
Conclusion
In conclusion, the future scope of data science is incredibly bright and full of opportunities. As technology advances and data becomes more abundant, data scientists will play a pivotal role in shaping industries, economies, and societies. From AI-powered solutions to personalized healthcare and sustainable practices, the potential applications of data science are vast and varied. To fully realize this potential, data scientists must not only embrace technical skills but also cultivate a deep understanding of ethics, privacy, and the responsible use of technology. As we move forward, data science will continue to be a driving force behind innovation and progress.
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cressidagrey · 1 month ago
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Love Letter
Pairing: Oscar Piastri x Felicity Leong-Piastri (Original Character)
Summary: Other people write love letters, Felicity Piastri reengineers tire degradation. 
Notes: Big thanks to @llirawolf , who actually knows what she is talking about and is the genius behind the science. She said this science "was understandable and accurate enough for fic." (Also I am aware that this is not believable, but hey, let me have fun 😂
(divider thanks to @saradika-graphics )
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By the time McLaren hit mid-season in 2024, Andrea Stella had become something of a veteran in the art of bracing for impact — the kind that came not from a crash, but from the Piastri household.
He had gotten used to it.
Oscar’s precision. His unnerving calm. The way he drove with the composure of a man triple his age and none of the ego.
Felicity, who wasn’t technically on the payroll, but might as well have had a desk in R&D. Who was so liked in the engineering department that Andrea had overheard an engineer asking Oscar like an overexcited puppy when his wife was going to come back and play with them. 
Felicity was always lingering at the edge of a race day.
Always watching. Always noticing.
And then there was Bee — small, serious, and so wildly intelligent it made his engineers nervous. She had literally seen an issue with their suspension during her first trip to the garage. Now, she asked about downforce balance mid-lunch and then drew airflow diagrams on her juice box.
Andrea had learned to expect brilliance from them.
But what Felicity handed him that morning wasn’t brilliance.
It was revolution.
It came in the form of a single-page drawing.
A3 paper. Hand-sketched. Neat annotations in clean block lettering.
She passed it over casually, like it was a grocery list. “Was thinking about deg last night. Couldn’t sleep. Just a theory. Don’t know if it’s actually useful, sorry.”
Andrea glanced at it.
Then really looked.
And stopped breathing.
At first glance, it looked like a cooling solution — rim cooling, a variation on brake duct design. Not uncommon. Not radical.
But then he saw it.
Phase. Change. Materials.
His eyes darted to the margin where she’d written:
PCM core set to activate at 276°C. Peak drawdown window ~30 seconds, reset threshold <210°C. Tapered air channel design for directional retention. Modeled after CPU heat-sink transfer.
Andrea looked up.
Felicity just shrugged. “Everyone’s been trying to brute-force cooling through airflow. I figured… maybe it’s not about keeping it cool. Maybe it’s about controlling the peak.”
It wasn’t theoretical.
It was elegant.
Andrea’s brain kicked into high gear. 
PCM — phase change materials — had been a whispered concept in F1 circles for years. The holy grail of thermal management. 
The idea that you could insert a material that would melt in response to a precise temperature range, absorbing energy as it changed state — holding a system in a stable thermal window. It worked in CPUs. Data centers. Rocketry.
But no one had ever made it viable in an F1 brake drum environment.
Not until now.
Not until this.
Not until it came from Oscar Piastri’s wife, at 2 a.m., in the quiet space between insomnia and motherhood.
Andrea blinked hard. “You know we’ve had engineers — PhDs — trying to crack this for years?”
She just shrugged. 
He had no words.
Just respect.
And the rising sense that something seismic had shifted.
He handed it straight to the sim team. They ran a closed simulation. Quietly. Then another. And another.
By the time they tested it under controlled parameters, the engineers were whispering about windowed degradation curves. About temperature floors. About thermal consistency that shouldn’t be possible.
Oscar was suddenly able to manage medium compounds like they were hard. The performance drop-off curve flattened — flattened. Andrea had never seen anything like it.
No magic bullet in F1 ever worked this fast.
But this?
This wasn’t a magic bullet.
It was physics. It was material science. It was control — without compromise.
They ran it again during a private test at Silverstone. And then — stealthily — implemented portions of the system into the race package.
By the time the 2025 season came around, Red Bull was accusing them of cheating. Mercedes was sulking. Ferrari was confused. 
The paddock wanted to know what the hell McLaren had done.
The answer?
Felicity Piastri.
When Andrea called her into his office, holding the latest race run data in one hand and a calculator in the other, she sat across from him sipping tea out of a mug with Bee’s name on it.
“You realize you’ve just solved one of the biggest unsolved problems in modern F1?” he said.
Felicity blinked. “I was just tired of watching Oscar hemorrhage tire life while driving perfectly.”
Andrea stared at her.
She added, a little awkwardly, “I didn’t… mean to change the whole season. I just wanted him to stop overcompensating for a thermal flaw no one was fixing.”
Andrea leaned back in his chair and said — for the first time in his career — “I am both terrified of and completely in awe of your entire family.”
Felicity just smiled and said, “Would you mind printing a copy of the new tire envelope profiles? Bee wants to compare the heatmaps to the old ones.”
Andrea buried his face in his hands. “Tell her to go easy on us.”
“I’ll try. No promises.”
They were rocket ships now. Every track. Every compound. Consistent, controlled, deadly fast.
And somewhere, deep in the McLaren server, the drawing still existed. In a scanned file. Named Piastri_Insomnia_Fix_v1.pdf
Andrea renamed it later that week.
"Found the Window."
Because that’s what it was.
A window — held open by a woman who thought differently. Who didn’t need the spotlight. Who just loved someone enough to stay up all night figuring out how to protect him from heat, chaos, and failure.
And somehow, she’d done the same for all of them.
***
Mark Webber had seen a lot in his career.
Title deciders. Broken bones. Politics dressed up as progress. He’d seen technical miracles and driver meltdowns and the rare, perfect moment when both came together and worked.
But he had never seen a technical revolution arrive folded in half on a single piece of A3 paper, annotated in gel pen and handed in like someone had just scribbled down the grocery list.
And he certainly hadn’t expected it to come from Felicity Piastri. Maybe he should have. 
He was standing trackside in China when Andrea Stella handed him the printout — not the PDF version with simulations, but the original. The drawing. The one that changed their 2025 season from promising to dominant.
“She gave me this on a Tuesday,” Andrea said, voice flat with disbelief. “Said it was just a thought. I’ve had people with entire departments fail to model this. She did it because she couldn’t sleep.”
Mark turned the page over once. Then again.
It was neat. Clean. Not showy.
Pressure curves, airflow vectors, the highlighted activation band of the phase change material she’d used to stabilize tire temp near the brake drum.
“Jesus Christ,” he muttered. “She’s a genius.”
He knew that. He had been aware of it for years. But it was something else entirely to see it in action. 
Andrea didn’t argue. “She just… wanted to help Oscar.”
Mark stared at the drawing again.
That’s when it hit him.
This wasn’t a flex.
This wasn’t about glory. Or proving herself. Or showing up a paddock full of men with degrees and dynos.
It was a love letter.
Written in airflow.
Signed in melting point theory.
Stamped in the stable temperature range of a tire that could now go ten laps longer without falling off.
Felicity hadn’t just solved degradation.
She had — quietly, brilliantly — rewritten the way Oscar raced.
Because he was hers.
And this was what loving him looked like.
Not flowers. Not poems. Just… making the world easier for him. A little softer. A little kinder. A little less brutal at 300km/h.
Mark let out a slow breath.
“Do you think she knows what she did?” he asked.
Andrea shrugged. “I think she knows why she did it. That’s probably enough.”
Mark folded the paper again — carefully, reverently — and tucked it back into the folder.
And in that moment, he didn’t see the terrifying engineering breakthrough.
He just saw a woman who loved her husband enough to change the laws of tire life —So he wouldn’t have to carry the weight alone.
***
Oscar had just come back from a long run on used mediums when Andrea called him into the office.
Nothing dramatic — just a quiet, “Got a sec?” as Oscar peeled off his gloves and handed his helmet to a mechanic. The kind of thing that sounded normal. Routine. Like maybe they were going to go over sector data or tire drop-off or which curb had tried to kill him today.
So when Andrea closed the office door behind them and reached into his drawer without saying a word, Oscar raised an eyebrow.
Then Andrea handed him a sheet of paper.
A3. Slightly folded. Faint graphite smudges along the margin.
 The original one. Still folded along the crease Felicity had made when she handed it to Andrea like it wasn’t the single greatest thermal breakthrough in modern tire strategy.
Oscar took it automatically.
Looked down.
And stilled.
There were notes in clean block print. Equations. Angled airflow paths, subtle thermal gradients, annotations on phase change material melt points and rim temperature drawdown.
Oscar’s throat went dry. His eyes scanned the drawing again, heart starting to race—not from adrenaline, but from recognition.
He knew that handwriting.
It was so her. The tidy script. The neat arrows. The absence of drama.
Just a brilliant mind trying to fix something that made the person she loved suffer.
He’d seen it on post-it notes stuck to Bee’s whiteboard. On margin scribbles in books Felicity had left lying around. On every note she slipped into his suitcase before he went to a race….every note that he then slipped into his racing gloves. 
Oscar looked up, voice quieter than it should’ve been. “This is Felicity��s.”
Andrea nodded once. “She gave it to me three months ago. Said it was probably nothing. Just an idea she had when she couldn’t sleep.”
Oscar sat down.
Because suddenly, his knees weren’t quite up to the task.
He stared at the drawing like it might vanish.
This was it.
The fix. The reason their tires held. The reason he didn’t fall off in stint two. The reason strategy meetings had shifted from damage control to aggression. The reason the car felt like it trusted him back for the first time in forever.
He felt it like a punch to the chest.
“She… she did this?”
“She did,” Andrea said. “And she didn’t want credit. Said she just wanted you to stop overcompensating for bad thermal management. That you were too good to keep bleeding lap time for other people’s mistakes.”
Oscar swallowed hard. His hands were shaking.
He looked back down at the paper.
At the numbers.
The calculations.
Oscar turned the page over.
A post-it was pressed to the back, Andrea’s handwriting.
“From Mark: ‘This isn’t just engineering. This is her love letter to Oscar — making the world around him easier.’”
Oscar’s heart stopped.
He stared at the sentence for a long, long time.
He read it again. And again.
The words didn’t feel like compliments.
They felt like someone had taken a flashlight and pointed it directly into his chest — illuminating something he hadn’t dared to articulate, even to himself.
Because that’s what it was, wasn’t it?
The sketch. The concept. The whole damn thing.
Felicity hadn’t set out to change a season.
She’d just wanted him to stop hurting.
To stop watching his tires fall apart under perfect driving. To stop fighting physics he couldn’t control. To stop carrying all that frustration on his own.
She’d stayed up at 2 a.m. not because it was her job — but because it was his dream.
She had never once made him feel like he had to win for her.
But God, she made him believe he could.
He blinked hard.
Thought about the way she kissed his temple when he came home late. The way she labeled Bee’s lunchbox with thermal guidelines for optimum snack temperature. The way she never said I love you like a performance �� only like a truth.
Then he looked up. “Mark… he really said that?”
Andrea’s voice gentled. “He did.”
Oscar stared at the page again.
“Yeah,” he said hoarsely. “Yeah. That’s her.”
And in his chest, where the engine noise usually lived — Where the pressure, the expectations, the sheer weight of competition settled — He felt something loosen.
Because winning was nice. The championship would be incredible.
But this?
Being loved like this?
That was better than anything he’d ever drive for.
***
The house was dark when he got home.
Not silent — not entirely. There was the low whir of the dishwasher. The cluck of a chicken outside, ruffling in its sleep. The soft creak of floorboards as he kicked his shoes off at the door and padded down the hall in his socks.
It was late. He hadn’t texted. He hadn’t needed to.
The bedroom door was open.
Bee was curled up in the middle of the bed like a starfish in mismatched pajamas, one hand still clutching the tail of her stuffed frog. Felicity was beside her, lying on top of the duvet, eyes closed, one arm slung across Bee’s little body like she was anchoring her in a dream.
Oscar stood in the doorway for a long time.
Just… watched them.
His wife and his daughter. One terrifying genius and one tiny one-in-training. Both of them unknowable and brilliant and his.
He swallowed around the knot in his throat and moved quietly to the other side of the bed, careful not to wake Bee as he lay down beside them.
Felicity stirred almost immediately, her breath catching as her body registered the warmth beside her.
Her eyes opened — drowsy, soft.
“Oz?” she murmured, her voice rough with sleep. “You’re home late.”
Oscar didn’t answer at first. Just slid his hand beneath hers and laced their fingers together. His thumb brushed over the back of her hand, slow and steady.
She didn’t push.
Didn’t sit up.
Didn’t ask.
Just waited.
And because she didn’t ask — because she already knew — he found his voice again.
“Mark saw the drawing,” he said, barely more than a whisper. “The one you gave Andrea.”
Felicity blinked slowly. “Oh.”
“He said it was a love letter. That you were making the world easier for me.”
She was still for a beat.
Then: “He’s not wrong.”
Oscar exhaled sharply. Pressed his forehead to her shoulder. “You didn’t have to do that.”
“I know.”
“I would’ve figured something out eventually.”
“I know.”
“But you did.”
She turned her head just enough to press a kiss to the crown of his hair.
Her voice was quieter than ever. “I’d do it again.”
Oscar’s breath hitched.
“I’d do it again tomorrow,” she said. “And the next day. And the day after that. If it meant you could breathe easier. If it meant you didn’t have to fight so hard just to keep pace with people who were working with better tools.”
He closed his eyes. Let the weight of her words settle over him like a blanket. Warm. Certain. Steady.
She ran her fingers through his curls once, twice.
And then she whispered: “You make the world easier for me, too. You just don’t notice it. You make it softer.”
Oscar kissed her shoulder. Didn’t move.
Didn’t need to.
Because she knew.
And he’d carry that with him — into every debrief, every qualifying lap, every moment on the podium.
This wasn’t just about racing.
This was home.
And it felt a hell of a lot like winning.
***
Lando found out in the most Lando way possible: completely by accident and one week too late.
He was in the simulator debrief when the topic of “thermal management integrity stability” came up — words that immediately made him want to die a little inside.
They were talking about their tire performance. Again.
Specifically, the fact that they could now absolutely cook it through mid-stint without falling off the cliff. And no one else could.
Lando was half paying attention — until one of the engineers muttered something about “F. Piastri’s material integration concept.”
Lando blinked.
“Sorry, whose what now?”
The room went quiet.
Andrea didn’t even look up from his screen. “Felicity. The drawing. You’ve seen it.”
“No, I have not seen it. Unless it was attached to a meme or came with a side of banana bread, I was not included.”
Will Joseph — Lando’s race engineer — slowly slid a printed diagram across the table.
Lando took one look.
Paused.
And said, “Wait. This is her?”
Andrea nodded without looking up. “Came up with it over insomnia. Gave it to me like it was a shopping list. It works.”
Lando stared at the airflow map, the PCM trigger temperatures, the annotated note that literally said ‘the goal is to stabilize the moment he usually starts slipping — give him room to breathe.’
He felt like someone had sucker-punched him with science and sentiment at the same time.
“Wait, wait, wait,” he said, sitting up straighter. “You’re telling me Felicity Piastri — as in, Oscar’s wife who wears motor oil like perfume and once fixed the coffee machine with a literal wrench — came up with the strategy that made our car an actual rocket ship?”
“Yes.”
“And it works.”
“Yes.”
“And she just gave it to you? No credit, no fuss, just… ‘here, I fixed the entire concept of high-deg tire strategy because I couldn’t sleep’?”
Andrea finally looked up. “Correct.”
Lando sat back, stunned.
He knew Felicity was scary smart. Knew she could rebuild a gearbox while calculating orbital velocity. Knew Oscar worshipped the ground she walked on and never made a big deal out of it because he didn’t need to.
But this?
This was something else.
“She didn’t do it for the team,” Lando said quietly, the realization hitting all at once. “She did it for him.”
Andrea didn’t say anything.
Didn’t have to.
Lando looked back down at the page — the margins, the equations, the gentle note that said “he’s too good to be held back by bad thermal behavior.”
And he felt it in his chest — that familiar ache.
Because that wasn’t engineering.
That was love.
The quiet kind.
The kind that doesn’t shout or show off.
The kind that stays up at 2 a.m. fixing something no one else thought could be fixed — just so the person you love can breathe easier.
So he doesn’t have to carry it all alone.
So he can go faster, safer, freer.
It was a love letter.
Not in flowers or poems.
In airflow and melting points.
Lando leaned back in his chair and exhaled. “Jesus Christ. She built him a better world.”
Will snorted. “She rebuilt tire degradation, but sure, let’s make it poetic.”
Lando didn’t even blink. “It is poetic. He’s the quiet guy. And she’s the quieter genius who knows exactly where he hurts and rewrites the laws of physics to help him anyway.”
Andrea tilted his head. “You’re getting sentimental again.”
“I’m right,” Lando shot back, still staring at the page. “He’ll win the title because she didn’t want him to bleed for it.”
He tapped the margin with his knuckle. “This is the kind of love that never asks for a podium. Just builds the car to get him there.”
And for once — no one had a comeback.
Because they all knew it was true.
***
They were in the driver’s lounge two days later, when Lando struck.
He’d been waiting for the perfect moment.
And Oscar, blissfully unaware, had just taken a bite of his protein bar like he wasn’t about to get emotionally roasted.
Lando stretched out across the sofa like a cat in a sunbeam and said, far too casually, “So… what’s it like being loved so much your wife reinvented tire degradation for you?”
Oscar blinked mid-chew. “…Sorry?”
Lando grinned. “Just curious. I mean, some of us get love letters or handmade birthday cakes. You? You get full-phase material integration strategies and temperature-controlled brake ducting. Romantic stuff.”
Oscar groaned, immediately regretting not hiding in the sim room instead. “Lando.”
“I’m serious,” Lando said, sitting up now, fully energized. “Felicity took one look at your stint data and said, ‘this man needs help. Let me just rewrite thermodynamics real quick.’”
Oscar rolled his eyes. “It wasn’t—”
“No, no,” Lando cut in. “Don’t you dare downplay this. The rest of us? We have to manage deg. You? You have a thermodynamic guardian angel in your marriage bed.”
Oscar flushed, the tips of his ears visibly pink. “She had a theory. That’s all.”
“‘Just a theory,’” Lando mimicked, using air quotes. “‘Just a casual bedtime sketch that turned McLaren into the most stable tire platform on the grid.’ My God, Oscar. She loves you so much it’s physically measurable.”
Oscar sank lower in his seat, muttering, “You’re insufferable.”
“You’re married to the Nikola Tesla of tire temp control. I deserve to be insufferable.”
“Lando—”
“She built us a better car because she hated watching you suffer.” Lando flopped dramatically. “Imagine. Being loved with that level of efficiency. Can you even comprehend?”
Oscar sighed, rubbing a hand over his face. “She’s just… always been smarter than all of us.”
Lando stopped mid-rant.
And smiled, softer this time. “Yeah. I know.”
There was a long pause.
Then Lando added, “Anyway. If she ever wants to fix my brakes, tell her I’m emotionally available.”
Oscar snorted. “Absolutely not.”
“What about Bee? Can she be bribed with juice boxes and data sets?”
Oscar shook his head, laughing now. “She’s already running her own simulations. She’s got standards.”
Lando grinned. “Just like her mum.”
Oscar looked down at the McLaren logo on his hoodie — the one Felicity stole all the time — and felt something warm settle in his chest.
He didn’t say anything else.
He didn’t need to.
But when he went home that night, he kissed Felicity extra softly — and whispered thank you against her temple like a promise.
And Felicity?
She just smiled, wiped her grease-smudged fingers on her jeans, and said, “Don’t thank me yet. Bee thinks we can improve the airflow angle by three degrees.”
Because love — in their house — was always a work in progress.
And always worth the effort.
***
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grison-in-space · 2 years ago
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Sure, but I still want to know their priors and sampling techniques. Failing that, using the most easily accessible methods to gather data can still yield potentially interesting information about overall dynamics even if we apply mathematical analyses that assume oversampling of queer users to "correct" the effects of snowball sampling. It's worth noting that sampling information about human sexuality is pretty much uniformly nightmarish in any case; this is actually not that much worse than published peer reviewed sampling efforts, horribly enough.
I am taking everyone who made a poll to gauge the True Percentage of Queers on Tumblr and putting them through a statistics course
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pitlanepeach · 2 months ago
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Radio Silence | Chapter Nine
Lando Norris x Amelia Brown (OFC)
Series Masterlist
Summary — Order is everything. Her habits aren’t quirks, they’re survival techniques. And only three people in the world have permission to touch her: Mom, Dad, Fernando.
Then Lando Norris happens.
One moment. One line crossed. No going back.
Warnings — Autistic!OFC, strong language, complex family dynamics, ableism.
Notes — This chapter has given me SUCH a hard time. Please enjoy it, I feel like I put my entire soul into it. Also… Fernando’s return is announced in the next chapter (everyone cheer).
Want to be added to the taglist? Let me know! — Peach x
2020
Silverstone came around in the blink of an eye.
Amelia sat perched on the edge of the engineering desk, her legs swinging absently, trainers knocking gently against the metal drawer units below. Her gaze swept across Alex’s side of the garage, quick, focused, restless. She wasn’t here to be social. She was here to figure something out.
Something wasn’t right.
She’d been quietly monitoring it since Austria; since testing in Barcelona, even. The data, the footage, the telemetry. There were too many inconsistencies between Max’s car and Alex’s. And sure, she understood the baseline logic. Max was Max. His driving style demanded everything from the car and then some. His feedback loop with the team was honed to a science. But even so, there shouldn’t be this much of a disparity.
Not in identical machinery.
Not at this level.
Her brows pinched, eyes narrowing at the readout on the nearest screen. She hated the term “second driver” with a passion. It grated against every instinct she had. But watching Alex’s side of the garage felt like watching a different team operate altogether. Different priorities. Different urgency. It wasn’t malicious. Not outright. But it was subtle. It was systemic. And it was stupid.
A puff of frustration escaped her nose. She’d already brought up some of her theories to Adrian, offhanded and careful, like she was floating curiosities instead of suspicions. He hadn’t disagreed. Hadn’t confirmed anything either. But she could see it — how he was watching now, too.
Still, it was driving her crazy.
The way Max’s floor and rear suspension packages were being iterated on faster. The microscopic setup tweaks that were tailored to his style but never translated for Alex. The way team radio responses came faster, the tone of them just slightly more reactive. She could hear the difference because she listened for it. 
It wasn’t cheating. But it wasn’t fair either.
And it was messy. Amelia didn’t like messy.
A burst of compressed air hissed across the garage as a mechanic adjusted Alex’s front wing, and Amelia’s head jerked toward it instinctively, eyes narrowing again. Her fingers twitched against her tablet, the internal debate warring louder than the buzz of the pit crew.
She lifted her ear defenders from around her neck and settled them over her ears. All of the noise softened to a low hum.
She glanced over her shoulder and spotted Max on the far side of the pit lane, deep in conversation with Christian by the pit wall. Calm and focused. He always looked like that before qualifying. Grounded. Unshakable.
Alex, by contrast, looked tense. He stood near his engineer, shoulders drawn tight, brows pinched as he nodded along, but his eyes kept flicking to the floor. Amelia watched for a beat longer, her heart tugging faintly. She wanted to fix it, whatever it was, but there was only so much she could do.
She looked down at her trainers.
They were her usual white ones, a little scuffed from the garage floors, but dependable. Comfortable. Familiar. But now, right at the edge of the left sole, something new: a messy swipe of orange marker.
LN4.
Her chest did something funny when she saw it.
Lando had crashed in her hotel room again, something that had quietly become routine. He always had his own room, but more often than not, he ended up in her bed instead of his. She didn’t mind. Would never say a word about it.
He was a good hugger now. He’d figured it out, finally, exactly how she liked to be held. Firm and tight enough to feel anchored. He’d taken to wrapping around her like a human shield, heartbeat steady, breath soft against the back of her neck. She hadn’t slept so consistently well in years.
He was usually gone before she woke up.
That morning had been no different. She’d blinked awake to an empty bed, the faint smell of his cologne still clinging to the hotel bedsheets. But when she’d gone to pull her trainers on, there it was; bright orange ink catching her eye.
Initials. A number. A quiet claim.
She didn’t know whether to roll her eyes or smile.
So she did both.
— 
The McLaren garage had its usual pre-quali buzz. Max Fewtrell leaned against the back wall, wearing a team guest lanyard and a vaguely amused expression as he watched Lando loll around in his race suit. 
“Alright, you’re being weirdly calm,” Max said, eyeing him. “You’re never this chill before quali. What is this? Zen Norris?”
Lando didn’t even look up from the banana he was unwrapping. “Just had a good night’s sleep, mate.”
Max raised an eyebrow. “Uh huh. Let me guess. In someone else’s hotel room?”
Lando gave him a slow, infuriating grin, then shrugged. “Maybe.”
Max stared at him. “No. Oh fucking hell. You’re not…?”
Lando just bit into the banana.
“You are,” Max said, half-laughing. “You’re back with her?”
Lando shrugged. “I wouldn’t say ‘back with’ like that, since we were never together in the first place, but yeah. We’re...talking.”
“Right,” Max said, drawing the word out. “Talking. In her bed. At night. Sounds familiar.”
Lando shot him a look. “Don’t start, mate. I’m still pissed at you for telling me to bin her off in the first place. Worst mistake of my life.”
“I stand by what I said then,” Max said, folding his arms. “And now she works for Red Bull. The actual enemy. She's probably hardwiring your secrets into Verstappen’s car while you’re asleep.” He said, eyes narrowed. 
Lando rolled his eyes. “She literally tells me nothing technical. I tried a few weeks ago, asked her what they changed on the rear wing. She said ‘carbon things’ and then threw a tortilla at my face.”
Max laughed. “Okay, yeah, that’s… okay, that’s funny.”
Lando looked a little too smug. “Exactly. Mate, I know what I’m doing. She’s worth it, you know? Just wish I’d realised it sooner.”
“Oh, you definitely don’t know what you’re doing,” Max scoffed. “You’re back in your feels, acting like it’s not completely mad that your maybe-girlfriend works for a team that would pay to see you finish outside the points every Sunday.”
“She’s not just some Red Bull lackey,” Lando said sharply, shoulders tensing. “She’s Amelia. She’s a fucking genius, Max. That car? It’s hers as much as it is Max’s or Alex’s.”
Max gave him a dry look. “You do realise how insane you sound?”
“I don’t care,” Lando said, straightening. “She’s the smartest person I’ve ever met. Yeah, I screwed it up before. But I’m not walking away from her again. Not ever.”
Max blinked. “Bit dramatic, mate.”
“Whatever,” Lando said, smirking. “You’re just bitter because I’ve a hot, genius in my bed and you’ve got a Twitch stream and a meal deal.”
“I brought you that Pret,” Max muttered.
“And I’m grateful,” Lando said, clapping him on the shoulder like a smug little shit. “But I’m also head over fucking heels, mate. So.”
Max groaned. “Jesus Christ. You’re unbearable.”
“Yup.” Lando tossed his banana peel perfectly into the bin. “Get used to it.”
Across the garage, an engineer called Lando over for a final briefing. As he jogged off, Max shook his head. “Mad bastard,” he muttered. “Completely lost the plot.”
—��
Amelia sat cross-legged on the floor of the Red Bull garage, the harsh overhead lights casting stark shadows across the slick concrete. Her tablet rested beside her, darkened screen still smudged with notes and numbers from the race. Her yellow golf ball rolled slowly between her hands, back and forth, back and forth; rhythmic and grounding.
Silverstone had always felt like a second home. Growing up watching races here, dreaming about being a part of it. Now she was properly in it. Deep in the heart of Red Bull Racing, elbows-deep in data, decisions, and disappointment.
Max had salvaged something, as he always did. P2 wasn’t nothing. But the numbers didn’t lie. Mercedes were still faster, smoother, untouchable on the straights. And the tire degradation? She closed her eyes, jaw clenching slightly. It didn’t make sense. 
She could feel the quiet frustration that had hung over the garage all weekend. Engineers working longer hours. Adrian pacing more. Alex struggling to connect the car to the track. And her, Amelia, trying to play translator between machine and man, and still somehow coming up short.
Her fingers tightened painfully around the golf ball.
It wasn’t failure, not really. But it wasn’t a win either. And that unsettled something in her. She wanted better. She wanted cleaner gains. More decisive margins. Less almost and more perfect.
Her thoughts drifted to Max, to the way he’d found her after the debrief and muttered, “We’ll get them next week,” like it was a promise more than reassurance.
She dropped her head, staring at the tablet, teeth digging into the inside of her cheek. There had to be something.
And then—
It hit her like a flash.
She blinked, straightened, then scrambled to unlock the screen, fingers flying. Rear aero wake management. Micro-channel re-shaping on the rear floor edge. She muttered to herself as she typed. “Shift the outer wake—no, no, narrow it, and bleed the turbulence—”
Her heart kicked up. Her breath got shallow. The pressure in her chest gave way to something electric. Her hands fluttered before she even realised, wrists snapping, fingers stimming with giddy, instinctive rhythm as the idea built in her head. She scribbled on the screen with her stylus like it was oxygen. She was grinning, properly grinning.
She barely registered the noise of the paddock returning to life behind her.
A Sky Sports camera had swung past, catching a glimpse of her in the garage, tucked between tool cabinets and telemetry units, flapping hands and bright yellow golf ball balanced in her lap. The presenter spoke softly over the shot. “And there’s Amelia Brown. A quiet presence in the paddock so far, but proving to be a very hard worker indeed.”
In the Red Bull hospitality suite, Christian Horner glanced up at the screen, watching the feed with his usual half-interested expression. “Ah, there she is. Our shining example of disability-positive hiring.” It was offhand. Meant as a joke, maybe. But it hung awkward in the air.
Adrian didn’t laugh.
He turned his head slowly toward Christian, expression unreadable. “She’s the most promising technical mind I’ve worked with in a decade. And she is working with me on merit alone.” He said mildly, eyes still on the screen.
Christian blinked. “Right. Of course.”
Adrian sipped his tea. Said nothing more. But when he looked back to the TV, his gaze was thoughtful.
And in the garage, Amelia kept working, entirely unaware of the camera, the commentary, or the conversation she’d just ignited. Her mind was moving too fast now to care about anything else.
She’d found something. Something big.
And she couldn’t wait to show Adrian.
— 
Max found her sitting alone on the pit wall. 
She had her yellow golf ball in one hand, thumb rolling over its surface absently. The other held her tablet, still filled with drawings and annotations, now marked with scribbled arrows and half-formed formulas.
Max climbed up next to her with the casual ease of someone who did it a hundred times a year. “You solved the issue,” he said, legs dangling over the edge.
Amelia blinked, as if pulled out of her own thoughts. “It’s not solved,” she said automatically. “It’s a direction.”
“A good one,” Max replied. “Adrian was very happy when you showed him. I saw it on his face.”
She smiled at that, a flicker of pride showing before she quickly tucked it away. One hand rolled the golf ball. The other hand jolted, maybe spurred on by a burst of excitement. She didn’t notice she was doing it.
Max did.
He watched it for a moment, then leaned back on his hands. “You were doing that earlier. With your hands. They showed it on the live feed.”
She froze, just for a second.
Max didn’t sound judgmental. Just curious. But still, something knotted tight in her chest. The instinct came fast, automatic; hide it, clench her fists, smooth out the edges. Pretend it hadn’t happened. Pretend she was just like everyone else.
But then she remembered what Adrian had told her, calm and firm that day in the design office, looking at her without even a flicker of doubt.
Why should you ever have to hide the manifestations of your greatness?
So, instead of retreating, she let her hands speak the language her brain needed. 
“Yeah,” she shrugged. “It’s called a stim.”
Max raised an eyebrow. “A what?”
“A… like, a repetitive movement. Helps regulate my focus. Or calm me down. Or… sometimes just helps me think,” she said, gesturing with the ball. “Ah, my hands flap on their own. And the golf ball’s got the right weight. Tactile enough to keep my hands busy while my brain does its thing. Means something to me.”
Max nodded slowly, eyes on the horizon. “You always do it when you're excited about something?”
“Sometimes. Or anxious. Or overstimulated.” She shrugged. “I mask a lot. Most people don’t notice the physical stuff. But the ball helps. I notice that I swing or bounce my leg a lot, too, but people don’t notice that as much.” 
He was quiet for a long moment. “So, it’s part of the autism?”
She turned her head toward him, eyes narrowing. Not angry, just curious. “You saw my Twitter?” She was very open about her diagnosis there, sharing informational and up-to-date medical journals. 
“I read part of your interview with RaceTech Weekly,” he admitted. “You said it’s not something you hide, but not something you announce either.”
“Yeah, well…” she exhaled. “Some people get weird. Or patronising. Or make jokes.”
“Christian,” Max said knowingly, a darker tone in his voice.
Amelia smiled, a bit twisted. “Adrian is nice about it, though.”
“Good.” Max looked at her again. “You shouldn’t be embarrassed.”
She stared at him. “I’m not—” And then paused. “Okay. I am. A little. But I’m trying not to be.”
Max just gave a half-nod, like that was fair enough. “You don’t need to explain it to me,” he said, kicking his foot gently out into the air. “I just wanted to know what it was. You looked happy.”
She blinked. “I was.”
He nodded again. “Good.”
Eventually, she bumped her shoulder against his. It was barely more than a nudge, but for Amelia, it was a big deal; intentional, physical contact she initiated. She didn’t do that often. Almost never. “Thanks for not being a dick about it,” she told him.
Max smirked, eyes flicking down to where their shoulders had touched before he leaned back. “Don’t thank me yet. Wait until I start asking to borrow the comfort golf ball during strategy meetings.”
“You’d lose it.” She sighed. 
“You’ll forgive me.” 
Amelia stared at him, dead serious. “No I wouldn’t.” 
It was late. Too late for anyone still at McLaren HQ except security and cleaning staff. 
Tracy stood across from him, arms folded, gaze cool and steady. She didn’t come to Woking often anymore, but something in Zak’s voice when he’d asked her to come by tonight had stopped her from saying no.
“You’re not sleeping,” Tracy said after a long beat. “You hardly even come home anymore.”
Zak rubbed both hands over his face, voice low. “I can’t stop thinking about her.”
“Good,” she replied, sharp but not cruel. “She should be at the front of your mind. Just like she’s always at the front of mine.”
Zak let out a bitter laugh and leaned forward, elbows on his desk, head bowed. “It’s been five months, Trace. Five months of silence. She won’t reply to my texts. Doesn’t even open my emails. I tried to speak to her at Silverstone and she looked straight through me. Like I wasn’t even there.”
Tracy sighed and lowered herself into the seat across from him, her expression tight. “You didn’t lose her because of one bad conversation, Zak. You lost her because you took something from her; something you had no right to. You tried to control what wasn’t yours.”
He looked at her, pain written into the lines of his face.
“She could’ve sued you,” Tracy continued, quieter now but no less firm. “Do you even understand that? Millions, Zak. She would never do it, of course, because she’s still loyal, still stupidly kind when it comes to you, but that doesn’t make what you did any less wrong. You treated her brilliance like a family asset. Like it belonged to you because she’s your daughter.”Her voice cracked, not with emotion, but fury. “That’s not how this works. That’s not how she works.”
“I didn’t mean it that way,” Zak said hoarsely. “I didn’t realise—Christ, Trace.”
“You were blind to it,” Tracy said, her voice steady but cutting. “Everything she was doing to elevate that team; improving car performance, supporting the drivers, stabilising Lando’s garage dynamic. She wasn’t just useful, Zak. She was essential. And now you’ve lost her to Red Bull.”
Zak sneered, bitter. “God. I just—why them? I would’ve understood Mercedes, maybe. Even Ferrari.”
Tracy didn’t flinch. “She’s built her own space in that garage already. They obviously respect her there. She’s on her way to helping Max Verstappen fight for his first world title. She’s not just surviving, Zak. She’s thriving.”
“I know that,” Zak said, his voice small, still dark and bitter. “I’ve watched. I’ve seen the press. Adrian Newey can’t stop signing her praises. But, Trace, I wasn’t even proud. I was angry.” He paused. “I didn’t understand it. I don’t even recognise her anymore.”
Tracy sighed. “She spent years trying to get you to see her. Always trying to fit herself into a box, hoping that maybe things would finally change and you’d suddenly realise what was standing right in-front of you.” 
Zak looked down. His hands were clenched together, knuckles pale. “I miss her so much,” he whispered. “I miss her laugh. Her rants. Even that awful yellow water bottle.”
Tracy pursed her lips. “The water bottle is gone. She has a golf ball now. Still yellow.” 
He looked up at her quickly. “A golf ball?”
Tracy smiled sadly. Shrugged. “Probably from her and Lando’s first date. I’ve never asked, but…” 
Zak blinked. “He… They went on a date? He managed to get her to go to a golf course?” 
Tracy nodded. 
Zak closed his eyes, taking a deep breath as he tried to pull himself together. “I just want a chance. One chance to tell her that I was wrong. That I see her now. That I’m proud of her. That I—”
Tracy leaned forward, her voice gentle but firm. “You have to let her come to you. Not the other way around. When has she ever responded well to being chased, hm?”
Zak blinked, fighting back the sting in his eyes. “Do you think she ever will, though? Come to me?”
Tracy stood, brushing a hand over his shoulder as she walked past. “She’s her father’s daughter. Stubborn. But eventually, something will happen, and your name will be the first one on her mind. Just… be patient. And come home, Zak. You need a shower.”
He watched her walk out, the soft click of her heels echoing in the stillness of the room. Then he turned back toward the window, staring out over the empty car bays and spotless garage beyond. The place that, in so many ways, had become his refuge; and his prison.
He could be patient. He could.
He stood up, grabbed his jacket, and followed her out. 
— 
iMessage — 20:03pm
Amelia I think we should go on a date.
Lando Norris No, no, no. Babe, no. I’m supposed to be the one to ask you on a date, not the other way around.
Amelia Why? You haven’t asked. I want to go on a date with you, so I asked.
Lando Norris Ok. I’m still paying. Doesn’t matter if you asked or not. I’ll plan it too.
Amelia Of course you are paying. Women don’t pay on dates.
Lando Norris Some ppl think they should 
Amelia Oh. Should I bring money then? 
Lando Norris No babe. Never.
Amelia :)
— 
He’d hired out an entire restaurant.
Fully staffed. Every table other than theirs empty.
It was insane. Completely over the top.
And yet, she couldn’t help but feel… warm about it.
Amelia ran her fingers along the smooth edge of her wine glass, her gaze drifting out the window as the sky darkened into soft shades of twilight. Normally, a full restaurant would have her on edge; the constant hum of conversations, the clatter of plates, the shuffle of waiters, the occasional laughter ringing too loudly in her ears. It always felt like too much. Too many sensory inputs, all at once.
Tonight, it was just them.
She glanced across the table at Lando, who was looking at her with that mischievous, bright-eyed expression. But there was something softer there too. A warmth, a genuine care she had come to expect from him.
"This is much better than golf," she said, trying to ease the tightness she felt in her chest. Her fingers tightened slightly around her wine glass, a small manifestation of her nerves. 
Lando stared at her for a moment, then laughed; a loud, free sound that made her heart skip a beat. "Yeah? I’m sorry I dragged you there. I won’t ever do it again, I promise." He had that usual teasing grin on his face, but there was softness in the way his eyes lingered on her.
Amelia shifted in her seat, glancing down at the menu in front of her. There were so many choices, so many different things to try, and the overwhelming amount of options made her stomach twist. Her mind started to race, analysing every single dish on the list, the flavours, the textures. Would they be too spicy? Too sweet? Would she like them or regret the choice? It felt like too much.
"I like the beach," she muttered, trying to shift focus. "And I like boats." But her thoughts kept circling back to the food. The choices were suffocating.
Lando seemed to notice the change in her, the tension creeping into her shoulders. "Boats, huh? So you don’t get sea sickness, then?” he teased, leaning forward a little, trying to pull her out of her head.
Amelia nodded absentmindedly, her mind still too loud. “Boats are just… private. Calm.“
He paused, studying her for a moment, before his voice softened. “If the options are too much, we don’t have to pick anything just yet. You’re here with me, we can go slow. The restaurant is ours until midnight. No pressure.”
She sucked in a breath. “I— I’m sorry,” she said quickly, her voice small. “I’ve never been here before. It’s nice, I just... I don’t know what I’ll like.”
Lando reached across the table, taking her hand and giving it a firm squeeze. “Well, after the amount of room service we’ve eaten recently, I think know what you like, and what you don’t. Want me to just order for you?”
Amelia blinked, startled by his offer. “What?”
He looked at her for a moment, his gaze softening. Then, without warning, he stood and walked around the table. Before she could react, he pulled her chair back, coaxing her to her feet. He guided her back to his side and gently settled her onto his lap. His left arm wrapped around her waist, secure but not too tight, pulling her closer. Amelia felt the tension drain from her body as she sank into him, her back resting against his chest.
“We can share, yeah? I’ll pick a few things, and we can try them together,” he murmured, his voice low and warm.
Amelia hesitated, her voice barely a whisper. “They’ll stare.”
She could feel her cheeks warming, the faint pressure of being so close to him in a public space, even if the restaurant was empty. But despite her discomfort, she didn’t want to move. His arm around her felt right, comforting in a way she hadn’t expected. It was perfect.
Lando rolled his eyes, brushing a strand of hair from her face. “Let them.” 
NEXT CHAPTER
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jcmarchi · 7 months ago
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A blueprint for better cancer immunotherapies
New Post has been published on https://thedigitalinsider.com/a-blueprint-for-better-cancer-immunotherapies/
A blueprint for better cancer immunotherapies
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Immune checkpoint blockade (ICB) therapies can be very effective against some cancers by helping the immune system recognize cancer cells that are masquerading as healthy cells. 
T cells are built to recognize specific pathogens or cancer cells, which they identify from the short fragments of proteins presented on their surface. These fragments are often referred to as antigens. Healthy cells will will not have the same short fragments or antigens on their surface, and thus will be spared from attack. 
Even with cancer-associated antigens studding their surfaces, tumor cells can still escape attack by presenting a checkpoint protein, which is built to turn off the T cell. Immune checkpoint blockade therapies bind to these “off-switch” proteins and allow the T cell to attack.
Researchers have established that how cancer-associated antigens are distributed throughout a tumor determines how it will respond to checkpoint therapies. Tumors with the same antigen signal across most of its cells respond well, but heterogeneous tumors with subpopulations of cells that each have different antigens, do not. The overwhelming majority of tumors fall into the latter category and are characterized by heterogenous antigen expression. Because the mechanisms behind antigen distribution and tumor response are poorly understood, efforts to improve ICB therapy response in heterogenous tumors have been hindered.
In a new study, MIT researchers analyzed antigen expression patterns and associated T cell responses to better understand why patients with heterogenous tumors respond poorly to ICB therapies. In addition to identifying specific antigen architectures that determine how immune systems respond to tumors, the team developed an RNA-based vaccine that, when combined with ICB therapies, was effective at controlling tumors in mouse models of lung cancer.
Stefani Spranger, associate professor of biology and member of MIT’s Koch Institute for Integrative Cancer Research, is the senior author of the study, appearing recently in the Journal for Immunotherapy of Cancer. Other contributors include Koch Institute colleague Forest White, the Ned C. (1949) and Janet Bemis Rice Professor and professor of biological engineering at MIT, and Darrell Irvine, professor of immunology and microbiology at Scripps Research Institute and a former member of the Koch Institute.
While RNA vaccines are being evaluated in clinical trials, current practice of antigen selection is based on the predicted stability of antigens on the surface of tumor cells. 
“It’s not so black-and-white,” says Spranger. “Even antigens that don’t make the numerical cut-off could be really valuable targets. Instead of just focusing on the numbers, we need to look inside the complex interplays between antigen hierarchies to uncover new and important therapeutic strategies.”
Spranger and her team created mouse models of lung cancer with a number of different and well-defined expression patterns of cancer-associated antigens in order to analyze how each antigen impacts T cell response. They created both “clonal” tumors, with the same antigen expression pattern across cells, and “subclonal” tumors that represent a heterogenous mix of tumor cell subpopulations expressing different antigens. In each type of tumor, they tested different combinations of antigens with strong or weak binding affinity to MHC.
The researchers found that the keys to immune response were how widespread an antigen is expressed across a tumor, what other antigens are expressed at the same time, and the relative binding strength and other characteristics of antigens expressed by multiple cell populations in the tumor
As expected, mouse models with clonal tumors were able to mount an immune response sufficient to control tumor growth when treated with ICB therapy, no matter which combinations of weak or strong antigens were present. However, the team discovered that the relative strength of antigens present resulted in dynamics of competition and synergy between T cell populations, mediated by immune recognition specialists called cross-presenting dendritic cells in tumor-draining lymph nodes. In pairings of two weak or two strong antigens, one resulting T cell population would be reduced through competition. In pairings of weak and strong antigens, overall T cell response was enhanced. 
In subclonal tumors, with different cell populations emitting different antigen signals, competition rather than synergy was the rule, regardless of antigen combination. Tumors with a subclonal cell population expressing a strong antigen would be well-controlled under ICB treatment at first, but eventually parts of the tumor lacking the strong antigen began to grow and developed the ability evade immune attack and resist ICB therapy.
Incorporating these insights, the researchers then designed an RNA-based vaccine to be delivered in combination with ICB treatment with the goal of strengthening immune responses suppressed by antigen-driven dynamics. Strikingly, they found that no matter the binding affinity or other characteristics of the antigen targeted, the vaccine-ICB therapy combination was able to control tumors in mouse models. The widespread availability of an antigen across tumor cells determined the vaccine’s success, even if that antigen was associated with weak immune response.
Analysis of clinical data across tumor types showed that the vaccine-ICB therapy combination may be an effective strategy for treating patients with tumors with high heterogeneity. Patterns of antigen architectures in patient tumors correlated with T cell synergy or competition in mice models and determined responsiveness to ICB in cancer patients. In future work with the Irvine laboratory at the Scripps Research Institute, the Spranger laboratory will further optimize the vaccine with the aim of testing the therapy strategy in the clinic. 
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pandemic-info · 9 months ago
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"Any chance we're wrong about Covid?"
It's a valid question many people earnestly think about — even the very cautious.
'it becomes important to ask: "what does the data actually say?"'
Quoting a few good answers from a thread:
"Covid left me disabled in 2020. I know with 100% certainty that I am not wrong about Covid. I live with the proof every minute of every day for the rest of my life."
"The insurance companies and government statisticians care, or rather they have taken an objective interest." > https://fred.stlouisfed.org/series/LNU01074597 > https://insurancenewsnet.com/innarticle/insurance-industry-coalition-forms-non-profit-to-study-excess-mortality
"There are parallels between how governments are responding to COVID-19 and how they responded to tobacco back in the day. “it would be a mistake to assume governments would automatically protect people from a public health threat in the face of more immediate economic considerations…there would be resistance to change that might be costly until evidence to justify it was overwhelming.”" > https://johnsnowproject.org/insights/merchants-of-doubt/
"I suspect most of us entertain this thought from time to time, especially when it’s this absurdly difficult and lonely to maintain a Covid Conscious lifestyle. But it’s important to remember that history is littered with people making terrible choices en masse: with handling past pandemics, the holocaust, slavery, witch burnings, etc. Hell pretty much everyone used to smoke and putting lead in everything was A-ok. Just because a lot of people believe something doesn’t mean they’re right. So it becomes important to ask what does the data actually say? The research and the statistical data on this subject paint an ugly but fairly quantifiable picture by which we can gauge our understanding of the situation and our choices in response to it. Read the science. Look at the data on things like Long Covid. There are also many of us who have already had our health absolutely ravaged by this virus or lost loved ones to it etc., and everyone in that position has first hand evidence for how dangerous this virus is. It’s tremendously difficult to swim against the current like we are and self-doubt is natural in those conditions, but that’s when seeking out factual information on the subject is the best course of action."
"But what it all comes back to for me is - say we're wrong, and covid is a big nothingburger and lockdowns are the root of all evil. Ok, well, what I'm doing is acting on the best information available to me at this time to protect my family. I can't regret that. I will always be able to look my kids in the eye and say "I did my best with what I had."" ... So if we're wrong - well, we wore masks, changed our social habits, reduced our consumerism and our contribution to the destruction of our planet, and reduced how often we got sick. None of those things are bad. If they're wrong, they and their kids are screwed. I'd rather err on the side of caution.
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