#aldosterone

[mcatmemoranda]

Doing review questions.

Hyperkalemia is a known side effect of ACE inhibitors and angiotensin receptor blockers such as olmesartan. The risk of hyperkalemia is increased with chronic kidney disease, diabetes mellitus, moderately severe to severe heart failure, NSAID use, and older adults. Chlorthalidone and hydrochlorothiazide can cause hypokalemia.

In men who are diagnosed with hypogonadism with symptoms of testosterone deficiency and unequivocally and consistently low serum testosterone concentrations, further evaluation with FSH and LH levels is advised as the initial workup to distinguish between primary and secondary hypogonadism. If secondary hypogonadism is indicated by low or inappropriately normal FSH and LH levels, prolactin and serum iron levels and measurement of total iron binding capacity are recommended to determine secondary causes of hypogonadism, with possible further evaluation to include other pituitary hormone levels and MRI of the pituitary. If primary hypogonadism is found, karyotyping may be indicated for Klinefelter’s syndrome.

Daily use of polyethylene glycol (PEG) solution has been found to be more effective than lactulose, senna, or magnesium hydroxide in head-to-head studies. Evidence does not support the use of fiber supplements in the treatment of functional constipation. No adverse effects were reported with PEG therapy at any dosing regimen. Low-dose regimens of PEG are 0.3 g/kg/day and high-dose regimens are up to 1.0–1.5 g/kg/day. Ref: Tabbers MM, DiLorenzo C, Berger MY, et al: Evaluation and treatment of functional constipation in infants and children: Evidence-based recommendations from ESPGHAN and NASPGHAN. J Pediatr Gastroenterol Nutr 2014;58(2):258-274. 2) Gordon M, MacDonald JK, Parker CE, et al: Osmotic and stimulant laxatives for the management of childhood constipation. Cochrane Database Syst Rev 2016;(8):CD009118. 3) Lauters R, Saguil A: Laxatives for the management of childhood constipation. Am Fam Physician 2017;96(7):433-434

Primary hyperaldosteronism should be suspected as a cause for hypertension if a patient has a spontaneously low potassium level or persistent hypertension despite the use of three or more antihypertensive medications, including a diuretic. This can be evaluated by checking a serum renin activity level and a serum aldosterone concentration and determining the aldosterone/renin ratio. Primary hyperaldosteronism typically presents with a very low serum renin activity level and an elevated serum aldosterone concentration. A 24-hour urine collection for 5-hydroxyindoleacetic acid (5-HIAA) would be used to evaluate for a neuroendocrine tumor, which can present as chronic flushing and diarrhea. Cortisol levels can be checked if Cushing syndrome is suspected. Hypertension can be present in Cushing syndrome, but it is typically associated with other signs such as obesity and an elevated blood glucose level due to insulin resistance.

Psychogenic tremor is characterized by an abrupt onset, spontaneous remission, changing characteristics, and extinction with distraction. Cerebellar tremor is an intention tremor with ipsilateral involvement on the side of the lesion. Neurologic testing will reveal past-pointing on finger-to-nose testing. CT or MRI of the head is the diagnostic test of choice. Parkinsonian tremor is noted at rest, is asymmetric, and decreases with voluntary movement. Bradykinesia, rigidity, and postural instability are generally noted. For atypical presentations a single-photon emission CT or positron emission tomography may help with the diagnosis. One of the treatment options is carbidopa/levodopa. Patients who have essential tremor have symmetric, fine tremors that may involve the hands, wrists, head, voice, or lower extremities. This may improve with ingestion of small amounts of alcohol. There is no specific diagnostic test but the tremor is treated with propranolol or primidone. Enhanced physiologic tremor is a postural tremor of low amplitude exacerbated by medication. There is usually a history of caffeine use or anxiety.

Ref: Crawford P, Zimmerman EE: Tremor: Sorting through the differential diagnosis. Am Fam Physician 2018;97(3):180-186.

I got 100% on the first quiz! :)

[karribabytarot]

Conn's Syndrome: Causes and Symptoms Explained

### Understanding Conn's Syndrome: Key Points for Your Health Conn's syndrome, or primary hyperaldosteronism, is a condition that can significantly impact your health if left unmanaged. It is caused by the overproduction of aldosterone.

Conn’s syndrome, also known as primary hyperaldosteronism, is a condition characterized by the excessive production of aldosterone, a hormone produced by the adrenal glands. This overproduction leads to an imbalance of sodium, potassium, and water in the body, which can result in high blood pressure (hypertension) and other health issues. Here are the key details about Conn’s syndrome: What…

[drugcarts]

undefined

A disorder in which the adrenal glands don't produce enough hormones.

[medicomunicare]

Aldosterone e malattia renale sono collegati: i nuovi dati aggiungono importanza alla relazione

Aldosterone e malattia renale sono collegati: i nuovi dati aggiungono importanza alla relazione

Il malfunzionamento del rene nel tempo può condurre all’insufficienza renale cronica (IRC), una condizione medica dalla quale si torna indietro solo con un trapianto renale. E i numeri globali non sono affatto confortanti: nel 2017, il 9% della popolazione mondiale, ovvero 697 milioni di persone, avevano una qualsiasi forma di IRC a vari stadi. L’aldosterone è un ormone steroideo secreto dalle…

[millerflintstone]

Gigabyte needs to buy a lottery ticket.

To date (as of 2022),  49 cases of feline PHA (Primary Hyperaldosteronism) have been reported, and it may be the most common adrenocortical disorder in this species.

I don't know if she's #50. Her vet said that there have only been 4 diagnosed in the past 6 years, but I'm guessing she meant in general. I initially thought she meant just GA.

[stuckinapril]

Is your url an ACE inhibitor pun? That’s my headcanon when you pop up on my dash

noooo haha it was originally intended to be “stuck in april” (a username w sentimental meaning to me) but a lot of ppl have sent me asks saying they thought it was “stuck in a pril”/an ACE inhibitor pun (for those of u who don’t know, most ACE inhibitors have the suffix -pril). I’m lowly starting to love it as a pre-med biochemistry major SO…. at this point I’m willing to run w either interpretation

[midnight-arandombanana]

I keep seeing people talk about the connection between Rhine and the shade of life, but I’ve always found this idea fun:

Rhine as the shade of life

Reincarnated from a (god? Are shades gods?) to a mortal who eventually gained control of their birthright, only to be rejected for their mortality

To her, the giving of life and taking it away are inextricably intertwined

But other people don’t see it that way

(Cough cough Pierro)

[chicago-geniza]

My true talent & curse is immediately parsing all information in meme format. Looking at bloodwork & muttering "What if the REAL non-potassium-sparing diuretic was the endogenous RAAS dysfunction we made along the way"

[creepygoth666]

Screw Procardia XL and the horrible side effects.

[deinheilpraktiker]

Eine hochintensive Behandlungsstrategie für Herzinsuffizienz reduziert das Risiko des Todes oder der Wiedereinweisung ins Krankenhaus Die schnelle Erhöhung der Medikamentendosen nach einem Krankenhausaufenthalt wegen akuter Herzinsuffizienz führte zu einem geringeren Risiko, innerhalb der ersten sechs Monate nach der Entlassung wegen Herzinsuffizienz zu sterben oder erneut aufgenommen zu werden, im Vergleich zur üblichen Behandlung, so eine heute im American Heart vorgestellte wissenschaftliche Forschungspräsentation Association's Scientific Sessions 2022. Das Treffen, das vom 5. bis 7. November 2022 persönl... #Aldosteron #Angiotensin #Ausbildung #BLUT #Blutdruck #CT #Diabetes #Diagnose #Forschung #Gesundheitspflege #Glucose #Hämoglobin #Herz #Herzinsuffizienz #Insulin #Intensivpflege #Kalium #Kardiologie #Krankenhaus #Krankenversicherung #Medizin #Mortalität #Niere #pH_Wert #Pulsschlag #Renin #Rezeptor #Typ_2_Diabetes #Vorhofflimmern #Wirksamkeit

[mcatmemoranda]

Aldosterone makes you absorb sodium and excrete potassium.

[taimoorkhan]

Primary aldosteronism, also referred to as Conn's syndrome, is a hormonal disorder characterized by an excess production of aldosterone by the adrenal gland. This can lead to various medical emergencies, including severe hypertension, electrolyte imbalances, and cardiovascular complications, which require prompt management in the emergency department (ED). The most common cause of primary aldosteronism is an adrenal tumor, although other etiologies such as adrenal hyperplasia and rare conditions such as autoimmune diseases or cancer infiltration should also be considered. Diagnosis is typically established through laboratory tests, imaging studies, and exclusion of secondary hypertension causes.

The management of primary aldosteronism-associated medical emergencies in the ED necessitates a comprehensive approach that involves identifying the underlying cause, correcting electrolyte imbalances, and controlling blood pressure. Severe hypertension, a common presentation of primary aldosteronism, can be managed with medications such as angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, calcium channel blockers, and beta blockers, which work by relaxing blood vessels and decreasing aldosterone production. Electrolyte imbalances, particularly hypokalemia and hypernatremia, can lead to serious complications including muscle weakness, heart arrhythmias, and kidney failure and should be promptly corrected through intravenous fluids and electrolyte supplementation. Cardiovascular complications such as heart failure and arrhythmias may also occur and should be managed by identifying reversible factors and providing appropriate treatment.

In addition to these acute management strategies, patients with primary aldosteronism may require long-term treatment to control their blood pressure and prevent further complications. This may involve the use of medications and lifestyle modifications such as a low-salt diet and regular exercise. In cases of an adrenal tumor causing primary aldosteronism, surgical removal may be necessary. To properly diagnose and manage primary aldosteronism, appropriate investigations in the ED may include laboratory tests to measure electrolyte and hormone levels, as well as imaging studies such as CT scans and MRIs of the adrenal gland. Further testing may also be necessary to exclude other causes of secondary hypertension and confirm the diagnosis.

[lxclerc]

𝐬𝐭𝐮𝐝𝐢𝐞𝐬 | 𝐜𝐥𝟏𝟔

summary… charles tries to help his girlfriend study but that proves to be difficult when he doesn’t understand a single thing requested… yes! warning… none. pure fluff.

note… another old drabble request from the graves of my inbox. also as a med student, i adore this idea so much

𝙢𝙖𝙨𝙩𝙚𝙧𝙡𝙞𝙨𝙩

charles has never been the brightest tool in the shed when it came to academics. he supposes it comes with the occupation. growing up, he cared far too much about racing that he had no space left in his mind to care about school too. he was always meant to be a formula one driver so he never cared about the cell or the mitochondria.

ironically, you were the exact opposite. like him, you’ve known what you were meant to be the moment you got ahold of your first book. you’re going to be a doctor, a healer and you’ve dedicated yourself to that dream.

the human body is a beautiful machine, much like the universe. every little cell and atom circulating its vessel holds a purpose, creating a balance between life and death. it’s majestic, truly and a little bit scary. if one thing failed then the entire system could collapse and so you studied and studied and studied for ways to keep that system going, to cure ailments and diseases.

you thrive off academic validation and a minor superiority complex and yet somehow you’re the most anxious person charles has ever met.

he’s madly in love with you. this is a fact. him and his dream that required him to constantly put his life at risk and you with your dream of helping and saving people. really it was a match made in heaven. and charles is madly madly in love with you.

that’s the only reasonable explanation as he pulled himself out of his sim practice, seamlessly moving around the kitchen of your shared apartment as he prepared an ice coffee for you.

you’re drained and you’re on the verge of breaking down and so when he wrapped his arms around you and offered to help you study for your finals, you’d all but cried in gratitude.

no, charles leclerc didn’t care about the cell and mitochondria and but he cares greatly for you and so he’d study it if it meant you’d finally allow yourself to rest.

unfortunately for him, you’re way past learning about the mitochondria. instead you’re studying your worst enemy aka pharmacology.

“angiotensin receptor blockers prevent vasoconstriction and aldosterone release, causing a decrease in blood pressure and peripheral resistance,” you recite from the top of your head, still looking like you’re on the verge of tears but slightly better.

charles shook his head as he held the book you’d given him to help you study, his glasses on. “non, non, amour. it says here it’s ‘angiotensin receptor blockers selectively bind to the angiotensin I receptors in the blood vessels to prevent vasoconstriction and in the adrenal cortex to prevent release of aldosterone then lead to decrease in BP caused by decrease in peripheral resistance and blood volume.’”

you sigh again but couldn’t help the chuckle that escaped you. the first time he did it, you’d gotten frustrated but at this point, your brain is far too fried to even get annoyed at him. especially when even he looks like he’s about to start crying.

you pushed away the book from his hand, clumsily crawling over to him as you wrapped your arms around his neck, pushing him down so he’d be laying on the sofa and you on top of him.

“my love, i don’t need to memorize everything word for word from the book,” you explain as gently as you can for the third time. you know he’s just trying his best to help you.

“why?” he frowned. “wouldn’t it be better if you knew it exactly from the book?”

you giggled. “perhaps but no med student would ever survive memorizing twelve inch books word for word. we’d simply all break down and die.”

you hold yourself up, pushing his hair off his forehead before removing his glasses. he still looks confused but a lot of things honestly confused charles. thank god he has a smart girlfriend to explain everything to him.

“stop worrying about it,” you say. “i’ve studied enough and we both need a break.”

he sighed in relief, tightening his arms around you. “thank god i felt like my brain was put on a pressure dryer for a minute there.”

taglist: @ricsaigaslec @dragon-of-winterfell @coffeehurricanes @privcherry7 @miniminescapist @sebsdaniel @strelcka @writing-about-current-obsessions @amsofftrack @lostinketterdam @bisexual-desi @cialovessirlewis @multilovebot @lovelynikol16 @troybolton-14 @ohthemissery @dr3lover @myescapefromthislife @sunf1owerrq @the6ccnsp6cyy @t-nd-rfoot @navixfr @xjval @gridbunny

[crosstheveil]

Health: Adrenal Glands

TCM: Jing, Kidneys

GNM: Off Track (cortex), Unbearable Stress (medulla)

Greek: Sanguine (cortex), Choleric (medulla)

Chakra: Root

Astrology: Mars, Aries-Libra; ex. managing adrenal health can be especially important for natal placements like Mars in Libra/7th, Mars in Pisces/12th, South Node conjunct Mars, etc.

The adrenal glands, which sit atop the kidneys, play a central role in the body's response to stress, fatigue, immune challenges, and several key physiological and metabolic functions. Issues related to the adrenal glands is very common yet highly under-diagnosed. They consist of two regions:

Adrenal Cortex: Derived from the mesodermal base substance cholesterol, the adrenal cortex produces hormones such as cortisol, corticosterone, aldosterone, and male sex hormones. These hormones play vital roles in physiological functions. Cortisol and corticosterone, known as stress hormones, contribute to the regulation of metabolism, inflammation, and blood sugar, and assist in long-term stress response by enriching the blood with minerals and glucose. Their anabolic effects also aid in healing and regeneration. Aldosterone helps maintain blood pressure by regulating the balance of salt and water in the body. The adrenal cortex's production of male sex hormones can influence the reproductive system. If unresolved, chronic stress may lead to excessive cortisol production, causing problems like weight gain and high blood sugar.

Adrenal Medulla: The endodermal adrenal medulla manages emotional and physical stress by producing the hormones noradrenaline, dopamine, and adrenaline. These hormones are pivotal in activating the "fight, fright, flight" response, a physiological reaction that occurs in response to a perceived harmful event or threat. This acute stress response increases heart rate, blood sugar, and mental alertness, along with other physiological changes. Chronic anger or emotional upheaval can strain the adrenal medulla, leading to an energetic drain.

Stress

The adrenal glands are highly sensitive to stress, and chronic stress can lead to various disorders:

Psychiatric Disorders: Neuroses, post-traumatic stress disorder (PTSD), depression, anxiety disorders, bipolar disorder.

Neurological Disorders: Migraines, peripheral neuropathy, dizziness, tremors.

Glandular Disorders: Issues related to other glands including the thyroid which is responsible for cell growth; for instance, uterine cancer, polyps, hypothyroidism, hyperthyroidism.

Cardiovascular Disorders: Coronary artery disease, stroke, heart attack, hypertension, arrhythmias.

Respiratory Disorders: Asthma, chronic obstructive pulmonary disease (COPD), difficulty in breathing.

Immunological Disorders: Possible tumor promotion, reduced resistance to infection, autoimmune disorders, chronic inflammation.

Metabolic Disorders: Diabetes, obesity, metabolic syndrome, difficulty in regulating blood sugar.

Gastrointestinal Disorders: Ulcers, irritable bowel syndrome (IBS), chronic indigestion, malabsorption.

Genitourinary Disorders: Impotence, incontinence, menstrual problems, urinary tract infections, kidney dysfunction.

Musculoskeletal Disorders: Muscle weakness, chronic fatigue, fibromyalgia, joint pain.

Skin Disorders: Acne, eczema, psoriasis, skin thinning.

Cysts and Cancer

Adrenal Weakness: If the adrenal glands don't produce enough adrenaline, the heart may pump slower, leading to fluid accumulation and cysts in the prostate, ovaries, and breasts. These cysts can harden and potentially lead to cancer.

Blood Flow: Increasing blood flow can help resolve cysts if addressed quickly.

Signs of Imbalance

Frequent sickness, fatigue, low libido, low backache, chronic health issues, dark circles under the eyes, hair loss, early greying, frequent urination at night, cold hands and feet, brain fog, pain and weakness in the lower back, loins, thighs, knees and lower body, urinary weakness and debility, polyuria and nocturia, impotence and male sexual dysfunction, moodiness and irritability, depression, muscle or bone loss, autoimmune conditions, chronic fatigue, hormone imbalance, body aches, unexplained weight loss, lightheadedness, skin discoloration (hyperpigmentation), weakened stress response, insulin resistance, sleep problems, weight gain, sweet and salty food cravings, difficulty getting up in the morning, increased PMS or menopausal symptoms, inability to handle stress, increased allergies, frequent sighing, cravings for salty foods, higher energy levels in the evenings, overuse of stimulants like caffeine.

Traditional Chinese Medicine (TCM)

Jing (essence): The statement by the Chinese that the kidneys harbor our Jing refers to the adrenals having the highest concentration of neural crest cell derivatives in the entire body. Strong Jing corresponds to robust characteristics like strong teeth, which are made by neural crest cells, while weak Jing relates to signs of aging like grey hair and deafness, also linked to neural crest cells. Jing's manifestations include the progression from youth to adulthood, reflected in functions controlled by the pituitary (aided by neural crest cells), and can be seen in the structure of the face and jaw. Neural crest cells also create the heart's connective tissue, affecting lifespan. Jing as a concept is not the same as neural crest cells but they represent the body's inherent organizational strength. Weak organizational energy leads to neural crest cells that don't form properly or function well, resulting in genetic disorders affecting facial development. The Chinese recognized these markers as indicators of weak Jing.

Kidneys & Urinary Tract: The adrenal glands are connected to the kidneys not just through the renal fascia, but also by way of the renal artery, draining into the renal vein, and receiving nerve connections from the renal plexus. The kidneys regulates the body's water content and are essential for maintaining healthy bones, as well as producing healthy bone marrow and blood. It determines the level of adrenaline and dopamine in the body, affecting our energy and rest. In addition, it forms a relationship with the heart through various hormones. During puberty, the adrenal cortex starts to produce sex hormones like testosterone and oestrogen, and this production continues throughout adulthood. Caffeine depletes kidney qi, yang, yin, and essence, contributing to liver and adrenal issues, and long-term exhaustion. Regular coffee drinkers, especially those who don’t feel its effects, may be nearing adrenal exhaustion. Adrenal fatigue is often considered a kidney yang deficiency. If left untreated, it can progress to a kidney yin deficiency. These deficiencies are often marked by a light low groaning tone to the voice, a darkish pallor under the eyes, negative attitudes of insufficiency or inadequacy, needing to sit and not being able to stand for long, and worrying about money. Additionally, those who experience traumatic shock or long term stress often have their hair turn gray or fall out.

Kidney Yang (medulla): Linked to the reactive sympathetic nervous system and the hormones adrenaline, dopamine, and norepinephrine, produced in the adrenals. A deficiency in kidney yang can lead to symptoms like cold hands and feet, edema, night urination, and low libido. This deficiency parallels disorders like adrenal fatigue, hypothyroidism, and sexual dysfunction. This condition is worsened by the use of marijuana, diminishing our natural drive, motivation, and willpower. Adrenaline is used to treat conditions like asthma, anaphylaxis, and slow heart rates. It works on the cell membrane's outside, which is known as the yang aspect of the cell. It never enters the cell but attaches to a receptor on the outside, initiating a cascade of chemicals that open or close gates on the cell's exterior. In the heart and muscles, adrenaline prompts more calcium to enter, which amplifies the force of contraction; in the lungs, it leads to the relaxation of the muscles, permitting more air to flow in; in the brain, it initiates the emotional reactions connected with fear.

Kidney Yin (cortex): Associated with the parasympathetic nervous system and the hormone cortisol, produced in the adrenals. A kidney yin deficiency may manifest as sore back, leg weakness, insomnia, and anxiety. It may parallel disorders like diabetes, high blood pressure, and hyperthyroidism. Although necessary for daily function and stress response, excessive cortisol can lead to fluid retention, osteoporosis, muscle wasting, depression, and diabetes. If our bodies stopped producing cortisol, it would result in significant illness. While adrenaline binds to the exterior of the cell (yang), cortisol is absorbed into the very core (yin). Contrary to the effects of adrenaline which are more immediate, the effects of cortisol can take years.

Greek Medicine

Hot Temperament: The adrenals are generally represented as stimulating and energizing various functions to adapt to stress.

Adrenal Cortex: Sanguine, nutritive, and anabolic, enriching the blood and decreasing swelling.

Adrenal Medulla: Choleric, energetic, and catabolic, stimulating acute stress response.

Faculty Support: Adrenal glands produce supplementary amounts of sexual hormones, bridging a connection between vital and generative faculties; supporting heart and lungs (vital), kidneys and pancreas in blood sugar regulation (natural), enhancing mental alertness and stimulating the sympathetic nervous system functioning (psychic), supporting male sexual function and response (generative).

Root Center: The adrenals form the basic energetic support for the entire organism, associated with the Root Chakra.

Kidneys & Urinary Tract: Weak adrenals may adversely affect the vitality and functioning of the kidneys and urinary tract, which are interlinked with the adrenal glands'. When the kidneys are not effectively eliminating fluids, it can lead to the accumulation of phlegm and moisture. Additionally, the kidneys have a connection to the soles of the feet which may be affected by cold conditions. Conditions of melancholy or devitalization of the adrenals, kidneys, and urinary tract often correlate with chronic fatigue.

Adrenal Exhaustion: Chronic stress and irregular habits can lead to fatigue, irritability, pain, and impotence in men usually caused by flare-ups of Choleric anger or any experiences which feel like a roller coaster. Sexual overindulgence also exhaust the adrenals.

Male Sexual Function: The adrenal glands provide energetic support for male sexual function. Issues with adrenal energy may result in sexual dysfunction, including impotence or premature ejaculation.

Blood Sugar Regulation: In instances of dangerously low blood sugar, the adrenal glands jump into action, raising levels through adrenaline. Chronic instability may involve adrenocortical hormones, aggravating factors in type II diabetes.

German New Medicine (GNM)

Adrenal Cortex (Off Track)

Conflict: Feeling like you've made a wrong choice or gone down the wrong path.

Under-Functioning: Waterhouse-Friedrichsen syndrome, adrenal gland insufficiency, Addison's disease. Reduced cortisol production, feeling stressed and tired.

Over-Functioning: Excess cortisol (Cushing's disease) with high blood pressure, round face, obesity, muscle atrophy or aldosterone (Conn's syndrome) with high blood pressure, low potassium, weak muscles, thirst, frequent urination.

Adrenal Medulla (Unbearable Stress)

Conflict: Extreme tension from stress, feeling overwhelmed. Something is beyond reach.

Diagnosis: Pheochromocytoma, neuroblastoma. High blood pressure, racing heart, increased blood sugar, sweating.

Astrology

Mars: This planet governs adrenaline, testosterone, male sexual function, playing a role in the catabolic metabolism where fuel is burned. It also oversees the release of toxins, the regulation of red blood cells, iron, and muscle tissue, including tendons and ligaments. It extends to the entire muscular system, embodying vitality and physical strength. The energy of Mars is hot and dry so it's temperament is Choleric. Mars co-rules the adrenals (with Aries/Libra) and the male genitalia (Scorpio).

Aries: Aries is a Choleric sign, and its will to action makes it prone to anger and stress, which deplete and weaken the adrenal glands. The sign is energetic, sharp-eyed, cheerful, and alert, but may become irritable and have a restless tendency to keep going until burnout. This can lead to eyestrain and poor vision as the health of the eyes is dependent on the strength of the adrenals. The preference for stimulants like chili pepper, caffeine, and their attraction to the Sun can overstimulate the adrenal glands, leading them to seek cooling substances like icy drinks, fruits, and seafood.

Libra: Libra, the Sanguine Air sign that rules the kidneys and lower back, is a counterbalance to Aries. The kidneys and genitourinary tract are only as strong and healthy as the adrenal glands, which are their energetic support. Underlying adrenal weakness and exhaustion weakens the kidneys and genitourinary system, leading to urinary debility, urinary tract infections, inflammation or irritation, uremia, and gout. Since male sexual function is also dependent on the strength and health of the adrenal glands, problems may arise in this area.

Aries-Libra Dynamic: Kidneys, adrenals, eyes, head and cranium, low back, lumbar spine, bladder, genitourinary system (especially male), hips and loins. Aries represents personal power, autonomy, honesty, and decisiveness, often leaning towards individualism and assertiveness. Libra, on the other hand, emphasizes cooperation, diplomacy, compromise, and social harmony. While Aries is direct and often acts alone, Libra seeks mutual choice and operates through consensus. This represents a struggle between competition and cooperation, selfhood and partnership, war and peace, doing and being. Finding balance is needed for acid/alkaline balance, as Aries tends to run acidic, and for hormonal balance, where Aries tends toward excess testosterone. The tension between these two forces may cause a lot of frustration and aggravation, particularly in males, manifesting as irritation or inflammation of the genitourinary tract.

Healing and Relief

Diet: Paleo; reduce caffeine, sugars and sweeteners, gluten, starch, white flour, processed foods, and hydrogenated oils.

Nutritional Supplements: Ionic Magnesium, B Vitamins, Omega-3 Fatty Acids, Vitamin C, Zinc, Probiotics, L-Theanine

Herbal Adaptogens: Ashwagandha, Rhodiola Rosea, Holy Basil, Licorice Root, Siberian Ginseng, He Shou Wu

Lifestyle Considerations: Address societal pressure to perform, lack of self-care, and the conflict in real life. Regular exercise of varied intensity. Practice meditation, mindfulness, Tai Chi, Qigong. Express creatively and spend time in nature. Align sleep schedule with circadian rhythm to nourish yin. Hydrate more and add salt to water. Avoid various toxins like dioxin or insecticides which contribute to adrenal malfunction. Spend more time in the sun each day. Don't sit for too long. Try wearing a haramaki, stretch cotton (for summer) or stretch wool (for winter).

These are research notes from the work of Daniel Keown, Michel Odoul, Michael Tierra, Lesley Tierra, Johan Boshwinkel, David Osborn, Judith Hill, Eileen Nauman, Björn Eybl, Caroline Markolin, Deb Shapiro, and Jody Smith.

[trans-axolotl]

do you know anything about late-onset congenital adrenal hyperplasia? i just found it on my file while looking for something else. i have an unrelated surgery coming up and i'm trying to figure out if this could have any effect on how my body handles that, especially wrt cortisol. but i can't find much on it at all, particularly how it affects ppl beyond infertility and sex characteristics. my impression is that at least the classic variant of it sounds like something intersex-related so i thought you might have heard of it. i remember asking my doctors for more information and they were basically like "don't worry about it unless you wanna get pregnant :)"

Hey anon.

So, late onset congenital adrenal hyperplasia, also called nonclassic congenital adrenal hyperplasia, is considered an intersex variation. (If you search NCAH on my blog or on @intersex-support, you might find some other posts about it). Because of the way it affects our testosterone levels and secondary sex characteristics outside of what is typically considered "female", late onset CAH is intersex, even if late onset CAH hasn't caused changes in genitalia.

Of course, there's no pressure to instantly start referring to yourself as intersex, or start participating in intersex community, but know that you are welcome here, and there are a lot of people who understand what it's like. I also have CAH, and I'm always happy to talk about it with anyone else. I know that it can be sort of shocking or overwhelming to get that information for the first time. Any feelings you have about it are completely valid. You can take as much time as you need to process. The community is here for you whenever you're ready.

In terms of surgery and CAH, there are some important considerations. For people with NCAH, there's going to be a range for how each individual makes and processes cortisol and aldosterone. Some people need daily glucocorticoid replacement therapy while others do not. However, even if you do not need daily steroid replacement, some people with NCAH need extra "stress dosing" of glucocorticoids when their body is under physical stress, such as during illness, injury, or surgery. It would be really important to talk to your surgeon, an anesthesiologist, and probably an endocrinologist before the surgery to make sure you know what your cortisol and aldosterone production is and make a plan if you need stress dosing during surgery or surgery recovery.

One book I would recommend for people with CAH is the Parent's Guide to CAH. In a lot of ways this book kind of sucks--it's directed towards parents, uses a lot of cissexist language, and uses a very medicalized model, but has some of the clearest nonacademic writing about what CAH is, how it works, treatment options, and talks about different considerations like surgery, illness, etc.

Please feel free to reach back out with any other questions, whether it's about CAH, intersex stuff, or if you want suggestions on any other resources. Thinking of you, anon, and hope your surgery goes well! 💜💛💜

[er-cryptid]

Hypokalemia Causes

-- gastrointestinal issues

-- periodic paralysis

-- insulin excess

-- renal problems

-- hypothermia

-- aldosterone

-- Cushing's syndrome

-- diuretics

-- insufficient intake

-- alkalosis

-- elevated beta-adrenergic activity

.

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