#alternative splicing

[bpod-bpod]

Making a Muscle

Details of the genetic and molecular mechanisms – including the control of alternative splicing (where one gene encodes multiple forms of a protein) – regulating the development of muscle revealed in fruit flies

Read the published research article here

Image adapted from work by Elena Nikonova and colleagues

Biomedical Center, Department of Physiological Chemistry, Ludwig-Maximilians-Universität München, München, Germany

Image originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)

Published in PLOS Biology, April 2024

You can also follow BPoD on Instagram, Twitter and Facebook

[medicomunicare]

L'immunità che dialoga costantemente col cervello: il ruolo segreto di C1q nel cervello che matura ed invecchia

Uno studio innovativo condotto presso il laboratorio di Beth Stevens, PhD, presso il Boston Children’s Hospital, ha rivelato che una proteina immunitaria influisce sulla sintesi proteica neuronale nel cervello che invecchia. Un precedente lavoro del laboratorio Stevens aveva scoperto che le cellule immunitarie nel sistema nervoso centrale, la microglia, aiutano a sfoltire le sinapsi nel cervello…

[fortunaestalta]

[emdotcom]

For years, I've been trying to put into words Why I give a single iota about Bendy & the Ink Machine, but it's such a tangled mess that no thread can be seperated -- they're all interwoven in a way that makes it hard to pick them out. The game, overall, makes me miserable, because I can see that there was love put into it, but a lot of it is thrown to the wayside in favor of a story that I think was retroactively improved by the sequel's recontextualizing of it, but is ultimately not worth the price of admission & majorly drops the ball.

It's easy to list things I don't like about it -- the gameplay is sparse, the combat is uninteresting, none of the chapters feel connected, the bugs that assault all my playthroughs & kill my saves are consistent & fill me with dread every time I open the game, the lack of thought in the contents of a chapter (chapter 3's wheel ""puzzle"" & the animatronic Bendy from chapter 4, in specifc, really grind my gears), which speaks to the amateurish & rushed way that the game was crafted -- there's a lot to hate, & it's easy to hate it. But I don't. Despite all that, I am compelled by this game, by what it's trying & failing & trying again to say.

It's really easy to understand why you dislike something. I couldn't have told you much about what I did like, in Ink Machine.

& then, I played Dark Revival. I didn't realize I liked the story of Ink Machine, until I played Dark Revival. It's a better made game, it's just not fucking interesting, to me, because it doesn't have a story worth tuning in to.

[coquelicoq]

i complain a lot about how difficult dumas's syntax is on my poor little brain, but for one harrowing moment i was compelled to imagine a world in which he spliced commas all over the place instead of using conjunctions and semicolons, and i realize now it could have been so, so much worse. thank you for not doing that, monsieur. i am finally learning to appreciate your writing style, 40 pages from the end of this 1400-page book. better late than never!

[kontaktlab]

From Samples to Success Discovering the Best Splice Alternatives

For music producers, access to a diverse and high-quality library of samples, presets, and MIDI packs is essential for creating exceptional tracks. While Splice has become a popular resource, several other platforms offer unique features that can enhance your music production process. This article will explore the best Splice alternatives, helping you find the perfect tools to take your music from samples to success.

Download Audiosed

1. Audiosed

Audiosed is a standout alternative to Splice, offering over 1 million premium samples, presets, and MIDI packs. Its unlimited download model allows producers to explore and use an extensive library without any credit limitations.

Key Features of Audiosed:

Unlimited Downloads: Access as many samples, presets, and MIDI packs as you need.

Diverse Library: Find sounds for any genre, from electronic to hip-hop to cinematic.

Efficient Workflow: Sync downloads directly to your desktop, organize files seamlessly, and drag-and-drop samples into your DAW.

Advanced Search and Filter: Quickly locate the perfect sounds with intuitive search and filtering tools.

Regular Updates: Access new content as it is added to the platform.

Flexible Subscription Plans: Choose from weekly, monthly, or annual subscriptions to fit your needs and budget.

Why It’s Great: Audiosed’s unlimited access model promotes limitless creativity, allowing producers to experiment freely and find the perfect sounds for their projects.

2. Loopcloud

Loopcloud offers a cloud-based sample management system, making it easy to access and integrate samples into your projects from anywhere. Its advanced features ensure that your samples fit seamlessly into your tracks.

Key Features of Loopcloud:

Cloud-Based Storage: Store and access your samples from any device.

DAW Integration: Sync samples directly with your DAW for a smooth workflow.

Automatic Key and Tempo Matching: Ensure your samples fit perfectly into your projects.

Extensive Library: Explore a vast range of samples, loops, and one-shots across various genres.

Why It’s Great: Loopcloud’s cloud-based approach and advanced matching features streamline the sample integration process, saving you time and effort.

3. LANDR Samples

LANDR Samples is part of the larger LANDR ecosystem, which includes mastering and distribution services. It offers a curated selection of high-quality, royalty-free samples across various genres.

Key Features of LANDR Samples:

Curated Collections: Access carefully selected samples and loops for guaranteed quality.

Integrated Services: Benefit from LANDR’s mastering and distribution tools for a comprehensive production workflow.

Subscription Plans: Choose a plan that suits your needs, from basic to advanced options.

Why It’s Great: LANDR’s integrated ecosystem allows you to handle multiple aspects of your production process within a single platform, streamlining your workflow from sampling to mastering.

4. Audiosed.com

Audiosed.com by Native Instruments offers a vast library of sounds and loops designed to integrate seamlessly with Native Instruments' software and hardware. This platform is ideal for producers who are already using Native Instruments products.

Key Features of Sounds.com:

Extensive Library: Access a wide range of high-quality sounds and loops.

Seamless Integration: Works perfectly with Native Instruments products, ensuring a cohesive workflow.

Subscription Options: Various plans are available to meet different production needs and budgets.

Why It’s Great: The seamless integration with Native Instruments products enhances the user experience, making it easier to incorporate new sounds into your existing setup.

5. Prime Loops

Prime Loops specializes in high-quality, cutting-edge sounds and loops across a variety of music genres. Known for their innovative and professionally produced samples, Prime Loops is a favorite among producers looking for unique sounds.

Download Audiosed

[vtgdog]

i always put it off but weaving in ends is really relaxing once i get started on it

[exhaslo]

Hiii！I love your stories!!But can you write about Miguel × hybridbunny！reader？that Miguel was a rich mafia or ceo and he bought reader from a black market or an auction.（ps：make reader sit on Miguel’s desk while he works and he ended up eating her out and fcking her hehehehehhehe）🐇🐇🐇🐇

Hehehehehehehehehehe

Warning: MINORS DNI, Smut, oral, rough sex, dirty talk, creampie

--------------------------------------------------------------------------

There were many pros and cons that came with being the CEO. Unfortunally, claiming ownership of Alchemax carried far more cons than the alternative. It did not help that Miguel took over the company from his corrupt father.

There were a lot of problems that needed to be fixed. Many were within the company itself; the associates to say the least. Miguel had to fire and clean up a lot of the corrupted associates' messes. This included having Miguel silently attend a black auction market.

Turned out, one of his former coworkers who worked in genetic splicing decided to test various animals on different people. While Miguel was so focused on Spiders that created Spiderman, his stupid coworker created hybrids and sold them on the black market.

Miguel just hoped that he could save as many people as he could. The work of tracking the others down was going to be a lot harder for him.

As Miguel sat in his VIP seat with a hood on, he watched the scum below him cheer with anticipation. None of these people cared. They just wanted new trophies. Miguel was going to buy as many hybrids were auctions and try to revert them back to regular humans.

-------

Miguel was about to lose faith. The auction was at the last bid and there had not been a single hybrid. Miguel did check and this was the only black market auction in the city. It was too dangerous for there to be anymore.

"Now! What you've all been waiting for, the most popular item during our shows! A hybrid!!" The announcer cheered.

Miguel nearly gasped, leaning forward as he watched the curtains unveil, revealing you.

"We got ourselves an adorable hybrid bunny!!! You know what they say about rabbits."

Miguel ignored the sea of laughter. You were standing on stand, shaking like a leaf. Before the announcer could even start the bid, Miguel yelled out an insane number. There were gasps in the crowd and barely anyone had the guts to go higher.

And just like that, you were bought by Miguel.

--------

You were hesitant as you followed your new 'owner' to his vehicle. The chain and collar still tight around your neck. Once you were seated in the back seat, you flinched as your tail got caught in the belt. You had to lower your ears, not wanting to hit the roof of the car.

"My apologizes, I'll get a bigger car." Miguel apologized as he entered the vehicle. You gave him a slight glare, "I'm not going to hurt you."

"Just fuck me," You whispered.

"No," Miguel sighed as he took the collar off once the car started moving, "I'm trying to right the wrongs that the former CEO of my company did."

You touched your neck, watching Miguel very carefully. You had an inkling of where this conversation was going, and it started to make your heart and body shake.

"My name is Miguel. I have no intention of using you for any purpose, but to try and undo what Alchemax did to you, if you would let me."

"Hah, so am I the lucky test subject?"

"No. I want to find all those who were experimented on. You were the first one I saved." Miguel noticed your hesitation and offered you a bottled water, "I have a room set up for you. Anything you want or need, just let me know and I'll get it for you."

"I suppose freedom isn't an option?"

"You and I both know what will happen if I let you go."

"Yeah, I know. Just wanted to hear your answer." You scoffed and leaned forward slightly, "I actually worked at Alchemax as an assistant. I don't think it will be easy to undo my DNA now that its been changed."

"I can try."

---------

It had been a few months since you were bought by Miguel. It came as a surprise, but he did mean what he said. You were living comfortably and Miguel was trying his absolute best to cure you. As you guessed, nothing worked.

That didn't stop you from wanting to help Miguel with his endeavor. Miguel had even rescued a few more hybrids during your stay with him. You couldn't help but feel a little jealous that you weren't his only one now. There was a simple reason as to why you felt like that.

You fell in love with Miguel.

You wanted to believe that Miguel liked you too, but you weren't sure what was holding him back. Perhaps guilt? Needing to see him, you started to hurry to his office. Thanks to your rabbit DNA, you were a fast runner.

"Miguel? Can I come in?" You asked with a knock at his office door.

"Of course, (Y/N)." He said with a smile, opening the door for you.

Before entering, your nose caught whiff of something delicious. Sniffing around, you ended up next to Miguel. You gently gripped his jacket, sniffing against his collar.

"(Y-Y/N), are you alright? Do I smell?" Miguel cleared his throat, careful to hold you back.

"Hm? O-Oh, sorry. You just smelled really good." You laughed nervously, wondering what was coming over you.

Miguel patted your head, assuring you that it was okay. You could only feel embarrassed again. This wasn't the first time your rabbit DNA caused you to do something silly or embarrassing. You were still having a hard time getting over making a 'secret room' in the building when winter was coming.

"Want to help me with something?" Miguel offered, motioning towards his desk.

You hurried over, taking a seat on his desk as Miguel pulled out some paperwork. Since it was hard for you to sit in regular chairs due to your tail, Miguel allowed you to have a spot on his personal desk. It felt like you were a trophy for him. One you didn't mind.

"So, what are you working on?" You asked. Miguel chuckled towards you as he leaned back in his seat,

"Company business."

"So how can I help?"

"You already are," Miguel chuckled again and leaned closer towards you, "I feel better having you next to me. I'm not as stressed."

Your cheeks started to burn up at his confession. Your heart was racing and you could feel yourself getting hot. This was bad. Lately, whenever you thought about Miguel you would get into a small frenzy, needing to relieve yourself. It had to be because of your rabbit DNA.

"(Y/N), are you alright?" Miguel asked, his hand against your forehead.

"Mhm," You winced slightly, shaking from his touch alone, "M-Miguel, I should...g-go," You stuttered, finding it hard to keep yourself together.

Miguel furrowed his brows as he gave you a quick check up. He checked your eyes, noticing the glossy lustful look, then your heart rate. Miguel inhaled deeply once he finally noticed you rub your legs together and your nipples perk.

"You're in heat?" Miguel muttered lowly, glancing at your once more, "Let me take-"

"N-No, let me stay," You whined, holding onto Miguel, nibbling against his shoulder, "I-I'm only...like this because of...of you,"

"Oh," Miguel resisted a groan, gently pushing you back, "Then, I suppose I need to take responsibility for you, huh?"

Oh, how those words turned you on even more. You whimpered and moaned against his touch as Miguel took off your pants. Your panties were soaked. You swore Miguel mumbled something under his breathe, but you were so zoned out that you couldn't hear him.

Next thing you knew, Miguel had taken your panties off and laid you back against his desk. He brought your legs around his head, making sure your tail wasn't crushed under you. His head directly in front of your vagina,

"My, my (Y/N), you should have told me sooner about your little problem. I could have helped you happily,"

"B-But-Ah~ M-Miguel~" You cried out as his tongue started to swirl against your folds.

Your eyes widen and your body arched as Miguel feasted. His tongue touching you in ways that your fingers could not. His aggressive licks and swirls against your clit causing that knot inside you to grow tighter.

"Ah~ R-Right...t-there~" You moaned, crying out your orgasm.

Miguel cleaned up your mess, his tongue now threatening to enter your drenched hole. Your whimpers and moans were delicious. He wanted to hear more, but he also didn't want to take advantage of your state. Licking your insides, Miguel hummed at your sweet taste. Your legs wrapping around his head.

'Miguel~" You whined, grinding your hips slightly.

"Now, now my little bunny, if you don't behave I won't be able to control myself," He hummed, sucking against your clit.

"P-Please...f-fuck me...I need you~" You whimpered.

Miguel felt his restraints snap. He flipped you on your stomach and inserted a finger inside your cunt. Your body shock as you moaned louder than before. Miguel groaned at how your cunt sucked his fingers in.

"Does my little bunny want to be fucked that bad? Even using your tail to seduce me." Miguel huffed, using his free hand to play with your tail.

Unable to take the pleasure, you cried out another orgasm the moment Miguel touched your tail. It was so sensitive. Pressing your face against his desk, you whimpered, begging for Miguel to fuck you. You needed him. You wanted him to make you feel good.

"Alright, I'll give my bunny what she wants."

"Mhm~ Y-Yesh," You babbled.

A sharp gasp escaped your throat as you felt Miguel's dick push through your folds. His cock stretched you out and filling you so perfectly. Your body felt so hot as his tip threaten to push your cervix. You could feel his shape every time your pussy clenched around him.

"A perfect fit. My little horny bunny likes this right?" Miguel chuckled as he started to thrust his hips into you at a rough pace, "My little horny bunny going into heat because of me."

"Ah~ Mhm~ M-Miguel~"

You swore you started to lose your common sense. Miguel was pounding the life out of your cunt and the air out of your lungs. Your vision kept blurring as you just focused on the feeling of him filling you.

You gasped as Miguel lifted your hips ever so slightly. His dick hitting your g-spot with each thrust while his free hand was playing with your tail. You were losing count how many times this man was making you cum.

"Does my little bunny want me to fill her up?" Miguel leaned over you, whispering your ear,

"Mphm~"

"I can't hear you, are you too fucked out to answer?" Miguel nibbled against your ear.

You pressed your ass up, "Inside~" You begged.

Miguel complied as proceeded to fill you with his cum. He moaned lowly, giving you a few more pumps before coming to a stop. Miguel started to pull out, but heard you whine in protest. A chuckle escaped his throat as he continued to slap his hips into you.

Miguel continued to fuck you until your heat finally died out. By the end of what seemed like endless fucking, both you and Miguel were out of breathe. Miguel had you seated against his lap, resting your body against his.

You whimpered tiredly, cum pouring out of your cunt. Miguel rubbed your back, his hand nudging against your tail slightly.

"Mhm,"

"Shh, it was an accident, baby." Miguel whispered, rubbing your upper back, "You should have told me when these heats started. I can make some medicine to help you."

"You're fine," You whispered lowly. Miguel chuckled, kissing your head,

"If that's the case, then it would be easier for you to stay at my place. I have been looking for a wife,"

"Mhm...I'll gladly...take that role," You muttered tiredly.

Miguel resisted a chuckle. He waited for you to fall asleep before dressing the two of you. He had one of his assistants bring your stuff to his place as Miguel took you home. He was going to make you as comfortable as possible.

But first, you both needed a shower.

-------------------------------------------------------------------------

Hope you enjoyed!!!!

[literaryvein-reblogs]

Some Editorial Vocabulary

definitions of terms during the writing, editing and publishing process

Acknowledgements: Text in which the author thanks those who’ve supported them.

Action beat: Short description that comes before, between or just after dialogue.

Adjective: A word that describes a noun.

Adverb: A word that describes a verb.

Adverbial phrase: A group of words that describe a verb.

Afterword: A concluding section, often reflecting on the book’s creation or providing additional context.

Anaphora: The deliberate repetition of words or phrases at the beginning of successive clauses for artistic effect.

Antagonist: An adversary. The character who creates obstacles and challenges for the protagonist, or behaves in a hostile fashion towards the protagonist.

Anti-protagonist: A protagonist whose own actions create opposition and conflict, often within themselves or against their own goals.

Apostrophe: A punctuation mark used to indicate possession, omission and, occasionally, a plural.

Appendix: Space in a book for material that doesn’t fit comfortably in the main text.

Asyndeton: Literary device through which a sentence’s structure follows the following pattern: A, B, C.

B-C

Back matter: Also end matter. Elements reserved for the back of a book, including appendix, glossary, endnotes, bibliography and index.

Beta reader: Test-reader who provides feedback on book.

Bibliography: List of all works cited in book, and any other work of interest to the reader.

Chapter drop: The space above and below the chapter title.

Character arc: Narrative that shows how a character changes and develops.

Characterization: The process of revealing a character's personality, traits and motives through actions and dialogue.

Colon: Punctuation mark that introduces additional/qualifying information about the clause it follows.

Comma splice: Two independent clauses joined by a comma rather than a conjunction or an alternative punctuation mark.

Conjunction: A word that connects clauses or sentences (e.g. ‘and’, ‘but’, ‘if’, ‘then’)

Copyediting: A review of grammar, punctuation, and spelling, ensuring consistency and accuracy in the manuscript's language.

Critique: Also manuscript evaluation. Report analysing a book’s strengths and weaknesses.

D

Denouement: The final part of the book in which all the plot strands are brought together and resolved.

Deuteragonist: A sidekick or confidante character who has the most influence on the protagonist, often helping them solve problems and overcome obstacles. Can be critical to driving the plot.

Developmental editing: Also structural editing. The improvement of a manuscript's structure, content, and overall narrative, focusing on big-picture elements. Attends to plot, characterisation, narration and pacing.

Dialogue tag: Also speech tag. Words that indicate which character is speaking (e.g. John said).

Dialogue: The lines characters speak in a book.

Diversity reader: Also sensitivity reader. Test-reader who checks for misrepresentation in books.

Double-page spread: Also DPS. The view of a printed book or PDF when opened so that the left- and right-hand pages are both visible.

Drama: The conflicts, emotional intensity, and impactful events that drive the plot and engage readers emotionally. The focus is on character relationships, motivations, and the consequences of their actions.

Dropped capital: Decorative first letter of the first word on the first line in a chapter. Larger than the rest of the text and drops down two lines or more.

E-F

Ellipsis: Punctuation mark that indicates a trailing-off or a pause.

End matter: Also back matter. Elements reserved for the back of a book, including appendix, glossary, endnotes, bibliography and index.

Endnote: Additional useful information at the end of a chapter or book.

Filter word: Verb that tells rather than shows (e.g. ‘noticed’, ‘seemed’, ‘spotted’, ‘saw’).

Folio: Somewhat old-fashioned term for page number. Also used to refer to a page.

Footnote: Additional useful information at the bottom of a page.

Foreword: A recommendation of the work written by someone other than the author.

Fourth wall: In books, the conceptual space between the characters and the readers.

Free indirect speech: Also free indirect style and free indirect discourse. Third-person narrative that holds the essence of first person thought or dialogue.

Front matter: Also prelims. Includes part title and title pages, foreword, preface and acknowledgements.

Full point: Period or full stop.

Full stop: Period or full point.

G-L

Glossary: Alphabetical list of important terms with explanations or definitions.

Habitual past tense: Uses ‘would’ or ‘used to’ with a verb to indicate events that happened routinely in a time past.

Half-title page: The first page of a book with any text on it; in a printed book, always a right-hand page. Contains only the main title of the book.

Head-hopping: Jumping from one character’s thoughts and internal experiences to another’s. Indicates viewpoint has been dropped.

Imprint: Publisher’s name.

Independent clause: A group of words that contains a subject and a predicate.

Index: Alphabetical list of all topics, themes, key terms and cited author names covered in the book, and the corresponding page numbers.

Information dump: Also word dump. Information that’s necessary to the story but isn’t artfully delivered, or weaved creatively into the narrative and dialogue.

Line editing: Also stylistic editing. The refining of a manuscript's language, focusing on consistency, clarity, flow and style at sentence level.

M-O

Maid-and-butler dialogue: Dialogue in which one character tells another something they already know so the reader can access backstory.

Manuscript evaluation: Also critique. Report analysing a book’s strengths and weaknesses.

Narrative arc: Also story arc. The structure and shape of a story.

Narrative authenticity: The believability and truthfulness of a story so that the characters and events feel real within the framework of the novel’s world.

Narrative distance: Also psychic distance. How close the reader feels to a character’s thoughts, emotions and experiences within a story.

Narrative: Story. The part of the book that’s narrated, excluding the dialogue.

Narrative style: The author's unique manner of storytelling, encompassing language, tone, viewpoint and other structural choices.

Narrative voice: The style, tone, and personality through which a narrator or character tells a story to readers.

Numerals, Arabic: 1, 2, 3 etc.

Numerals, Roman: i, ii, iii etc.

Omniscient: All-knowing. Refers to a viewpoint style in fiction writing.

Overwriting: Using too many words on the page. Often characterized by repetition and redundancy.

P

Page proofs: A file that’s reached a stage in the publishing process where the text and images of a manuscript have been laid out in their final format.

Pantser: A writer who doesn’t outline or plan story structure, but flies by the seat of their pants.

Period: Full stop or full point.

Perspective character: Also viewpoint character. The character through whose eyes the story is primarily told. The narrative lens through which readers experience events, thoughts, and emotions within the story.

Plot: The sequence of events in a novel.

Point of view: Also viewpoint and POV. Describes whose head we’re in when we read a book, or whose perspective we experience the story from.

Polysyndeton: Literary device through which a sentence’s structure follows the following pattern: A and B and C.

Predicate: The part of a sentence that contains a verb and that tells us something about what the subject’s doing or what they are.

Preface: An explanation of the purpose, scope and content of a book, and written by the author.

Prelims: Also front matter. Includes part title and title pages, foreword, preface and acknowledgements.

Pronoun: A word that replaces a noun (e.g. I, you, he, she, we, me, it, this, that, them those, myself, who, whom). Pronouns can act and be acted upon like any noun.

Proofreading: The final pre-publication quality-control stage of editing where any final literal errors and layout problems are flagged up. Comes after developmental editing, stylistic line editing and copyediting.

Proper noun: A named person, place or organization. Always takes an initial capital letter.

Protagonist: The leading character in a novel, often facing central conflicts and driving action.

Psychic distance: Also narrative distance. How close the reader feels to a character’s thoughts, emotions and experiences within a story.

Purple prose: Overblown, poorly structured writing with strings of extraneous and often multisyllabic adjectives and adverbs.

Q-R

Quotation mark: Also speech mark. Punctuation that indicates the spoken word. Singles or doubles are acceptable.

Recto: The right-hand page of a book.

References: List of all the works cited in your book.

Roman typeface: Not italic.

Running head: Text that runs across the top of a page (e.g. title of the book, chapter title, author’s name).

S

Scene: a distinct segment or building block where specific actions and events unfold in a setting.

Scene technique: The use of dialogue, action, setting, and tension to craft compelling moments in the story.

Semi-colon: A punctuation mark that indicates a stronger pause than a comma between two main clauses.

Sensitivity reader: Also diversity reader. Test-reader who checks for misrepresentation in books.

Speech mark: Also quotation mark. Punctuation that indicates the spoken word. Singles or doubles are acceptable.

Speech tag: Also dialogue tag. Words that indicate which character is speaking (e.g. John said).

Story arc: Also narrative arc. The structure and shape of a story.

Structural editing: Also developmental editing. The improvement of a manuscript's structure, content, and overall narrative, focusing on big-picture elements. Attends to plot, characterisation, narration and pacing.

Style sheet: In which an author or editor records stylistic and language preferences, and tracks who’s who, what’s where, and when X, Y and Z happens.

Stylistic editing: Also line editing. The refining of a manuscript's language, focusing on consistency, clarity, flow and style at sentence level.

Subject: The thing in a sentence that’s doing or being something.

Subplot: A secondary storyline that supports and enhances the main plot of a narrative.

Suspense: The tension, uncertainty and anticipation created by withholding information, raising stakes or placing characters in imminent danger. Readers are kept guessing or forced to ask questions.

Syndeton: Literary device through which a sentence’s structure follows the following pattern: A, B and C (or A, B, and C).

T

Talking-heads syndrome: Dialogue that isn’t grounded in the environment or the characters’ responses to that environment.

Tense: The form a verb takes to indicate when an action happened in relation to the telling of it.

Tension: The emotional strain or suspense created by unresolved conflicts, stakes or uncertainties that keep readers engaged.

Tertiary character: A functional character who gives the story realism and depth, but doesn’t significantly impact on or influence the plot or the development of the other characters.

Theme: The novel’s central idea or message about life, society, or human nature.

Title page: Includes full title (and subtitle if there is one), author’s name, publisher’s name, logo, volume number, and edition.

Transgressor: A character who commits morally, socially, or legally questionable acts.

Tritagonist: Third most important character, who often provide regular emotional or physical support, but don’t determine how the story develops.

U-W

Unreliable dialogue: Dialogue that doesn’t match a character’s true voice, mood or intent.

Unreliable narrator: A character whose telling of the story cannot be taken at face value. They may be naïve, confused, or deliberately manipulative.

Verb, intransitive: A verb that doesn’t have a direct object (e.g. ‘I giggled’).

Verb, transitive: A verb that has a direct object (e.g. ‘wrote’ in ‘I wrote a book’).

Verb: A word that describes doing. Can refer to a physical action (e.g. to dig), a mental action (e.g. to wonder) or a state of being (e.g. to be).

Verso: The left-hand page of a book.

Viewpoint: Also point of view or POV. Describes whose head we’re in when we read a book.

Viewpoint character: Also perspective character. The character through whose eyes the story is primarily told, and the narrative lens through which readers experience events, thoughts, and emotions within the story.

Vocative: The form of address for a character directly referred to in dialogue.

Word dump: Also information dump. Information that’s necessary to the story but isn’t artfully delivered, or weaved creatively into the narrative and dialogue.

Source

[princip1914]

I recut the kiss from Good Omens to emphasize Aziraphale kissing back. I already posted the longer version (yes, I have made alternate cuts of my kiss alternate cut, yes I know this is ridiculous) but I realized I liked it in shorter gif form better. After the cut is the OG kiss for comparison and some notes on my process.

Edited Kiss:

Original Kiss:

On the longer version, I had some people ask what I changed. Essentially, what stood out to me when I saw the original version of the kiss was that it was just so...choppy. Particularly, the cut right before they break apart where we go from Aziraphale's hand on Crowley's back to him waving it around in the air, just didn't look natural to me. The original version seems to splice together several takes of a shorter kiss, with some pieces of the kiss out of order from how it was probably acted:

In the first cut of the sequence we see Aziraphale from over Crowley's shoulder and his eyes are open and he looks shocked and uncomfortable, then he relaxes into the kiss a bit and closes his eyes and his hand comes up to Crowely's shoulder and caresses it. My guess is this is the sequence and duration of the kiss from start to (nearly) finish as it was blocked and acted. But the kiss as it appears in the show is much longer than the acted kiss. From that first cut of Aziraphale's face seen over Crowely's shoulder we go to:

A wide cut where Aziraphale is waving his arm in the air and looks uncomfortable--likely filmed at the start of the kiss from a different angle and then spliced in.

A close up of Aziraphale stroking Crowley's back which seems to me to come from the end of the kiss, once he has relaxed into it. (This is the one all the girlies are gif-ing and yeah, it's a great shot so I'm glad the fandom has gone wild for it!)

Another shot from the relaxed bit of the kiss which is a close up on their faces with Aziraphale leaning in a bit

The last shot of the kiss where Aziraphale's arm has come off Crowely's back again and he's waving it in the air and looking uncomfortable as Crowley pulls away. I think this shot may actually also be from the start of the kiss, or it is actually how the end of the kiss was blocked out, but if so there's a section of it that's missing because we don't see how Aziraphale's hand moves from Crowley's back (shot 3) to waving in the air. This isn't really a continuity error as presumably Aziraphale has been moving his hands around during shot 4 while the viewer was being treated to a close up of their faces, but it registers as a continuity error because the emotional vibe of shot 4 is Aziraphale starting to get into the kiss and lean in, while the hand off the back in shot 5 makes the viewer feel like he is pulling away and uncomfortable again.

In editing the sequence, I simply moved pieces around to try and tell a story that was more emotionally coherent, with Aziraphale starting shocked and uncomfortable, relaxing into the kiss slightly, and then stepping away. I chopped up the long sequence in shot 1 and used the relaxed part of it instead of the beginning of shot 5. I also switched shot 3 and 4 so that we see a wide cut where Aziraphale looks uncomfortable and his hand is visibly in the air, to a close up shot of their faces where he starts to get into it. Then we are in the home stretch with the tender hand on the back and then Aziraphale's face as he holds Crowley close to him (formerly the end of shot 1) before they break apart.

[bpod-bpod]

Splice of Life

Splicing – the production of different forms of a protein from a gene's DNA instruction – in a sex-specific way occurs throughout the genome at the very earliest stages of embryo development

Read the published research paper here

Image from work by Mukulika Ray and colleagues

MCB department, Brown University, Providence, RI, USA

Image originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)

Published in eLife, March 2023

You can also follow BPoD on Instagram, Twitter and Facebook

[medicomunicare]

Indagando sull'autismo: le complesse interazioni fra dopamina, molecole di adesione ed energia cellulare

ASD e alterazioni della trasmissione cerebrale Il disturbo dello spettro autistico o ASD è un disturbo dello sviluppo che di solito si manifesta nella prima infanzia. Sebbene i risultati clinici varino notevolmente da caso a caso, l’autismo è caratterizzato sia da un interesse limitato per l’interazione sociale che da un comportamento ripetitivo. Ciò coincide con le interruzioni nella…

[fortunaestalta]

[kevinzhechair]

Meet the totally normal skeleton monster, not at all a timeline splicing Alien!!

Their name is Gleep, their pronouns are yes/all (he doesn't care about pronouns).

He used to be a commander of an alien arsenal who sneaked into alternative timelines to get code. Sometimes destroying or corrupting aus in the process.

After an injury, leaving it unable to do their job. The higher ups of the society decided not to kill them. Rather send her to a safe timelines the commanders had no need for (Underswap 113), as a type of vacation for his efforts.

They did not tell him that outright, so he still believes that the timeline is being used. Although that is not the case. The commanders enjoy his insane ramblings when he calls.

He's very up his own ass. Gleep is based off if you couldn't guess Zim from Invader Zim, but also Gnarpy from Regretavator. Why, because it's fun and I can.

[honorarysimp]

Uncanny Distortion

Summary: Woodsboro, California is a small town that’s never known peace. For decades, people have gone missing without a trace. As the disappearances amp up, a Private Investigator is hired to crack the case. Will urban legends overshadow logic, or will the unexplainable lead to more questions?

Pairing: Tara Carpenter x Fem!Reader

Tags/Warnings: mature language, mentions of unsettling and disturbing events, childhood trauma, substance abuse, violence, angst, character deaths, slowburn; suggestive themes(18+)

AN: My take on an alternate reality of the Scream Universe, if it were lovecraftian horror spliced with uncanny folklore. Inspired by the feeling I got listening to this.

~Masterlist~

[kaidanworkshop]

Workshop Progress: Spring Update

Happy Pride Month Workshop Spectators! It's hot out there, so make sure you're staying safe and hydrated while celebrating in your respective communities. A lot has been going on behind the scenes since our last update; we've been busy tying up loose ends across the board as we finalize Kaidan Revoiced: Community Expansion, which is frankly, very tedious - lots and lots of spreadsheets. Nonetheless, all the miscellaneous minutiae we're ironing out is to ensure our upcoming surprise to the community, [REDACTED], runs smoothly. We've also got one final poll for you before our official release, then it's back to the grindstone for the Workshop staff as we focus on splicing and processing the last lines for implementation. As per our last poll, the community voted to have us postpone the mod release until it is in a finalized state.

Afterwards, we spent most of April going over the script one final time to catch any extra lines we may have missed for our commission covering the last of the original Kaidan 2 script. We also held a few live sessions on our Discord going over the few bits of Workshop Original content that will be going into this first version: the alternative platonic Autumnwatch route, the Nickname & Pronoun system, and the rewritten Pieces of the Past quest. All in all, this new content amounts to just over 100 extra lines; this version of the mod will be preserved indefinitely on our mod page in the future. As we move forward with creating and implementing more Workshop Original scripts post launch, users will still be able to download and use this version if they prefer. Finally, throughout the end of April and all of May, we've been running a closed beta for KR:CE with the help of volunteers from other Skyrim modding teams. We've been able to track down a few more bugs, confirmed that our new quest fail safes work (woo!), and discovered a handful of mods that were incompatible with KR:CE, requiring us to move a few things around.

During our closed beta testing, we did get a recurrent piece of feedback that we'd like to discuss with the community at large. Similar to the audio distortion Kaidan has in Kaidan 2, the voice lines for the Dremora in Kaidan's personal quest, as well as Myriah, the priestess in the forest wedding, are very badly distorted. One of the key reasons the Workshop was formed was to address the audio distortion that existed in the Kaidan 2 mod, so it feels incomplete to not address this issue. We'd like to hire two new voice actors to rerecord these lines for implementation, the cost of which would be approximately $40 - $60 USD total (due to how few lines we need), taken from our current budget surplus. As always, we turn to the community regarding any decisions relating to how we allocate your donations; you can vote on this proposition here through June 14th. As always, we thank you for your interest, your patience, and your support! We can't wait to announce [REDACTED], and the official release date of KR:CE to the community.