#propanoic acid

[whats-in-a-sentence]

Table 23.1 lists several of the unbranched aliphatic carboxylic acids found in the biological world (e.g. figure 23.1), along with the common names of each.

"Chemistry" 2e - Blackman, A., Bottle, S., Schmid, S., Mocerino, M., Wille, U.

[tenth-sentence]

The first four aliphatic carboxylic acids (formic, acetic, propanoic and butanoic acids) are infinitely soluble in water because the hydrophilic character of the carboxyl group more than compensates for the hydrophobic character of the hydrocarbon chain.

"Chemistry" 2e - Blackman, A., Bottle, S., Schmid, S., Mocerino, M., Wille, U.

[xtruss]

Scientists Find Origin-of-Life Molecule in Space for First Time

— By Jess Thomson | August 8, 2023

NASA image of the Tarantula Nebula star-forming region taken by Webb’s Near-Infrared Camera. A molecular cloud in interstellar space has been found to contain carbonic acid for the first time. NASA, ESA, CSA, AND STSCI

molecule common to Earth and usually associated with life has been detected in the depths of space by scientists.

Carbonic acid (HOCOOH), which you may know as the chemical that makes your soda fizzy, was discovered lurking near the center of our galaxy in a galactic center molecular cloud named G+0.693-0.027, a study published in The Astrophysical Journal revealed.

This marks the third time that carboxylic acids—this class of chemicals, often thought to be some of the building blocks of life—have been detected in space, after acetic acid and formic, and the first time that an interstellar molecule has been found to contain three or more oxygen atoms.

"Our observations have allowed us to know that carbonic acid, which until now had remained invisible to our eyes, is relatively abundant in space, which makes it an essential piece to understand the interstellar chemistry of carbon and oxygen, two of the fundamental chemical elements in any prebiotic process," Víctor M. Rivilla, a researcher at the Spanish Center for Astrobiology and co-author of the study, told German broadcaster Deutsche Welle (DW).

"This result confirms that the path we have chosen is the right one to search for, and detect more molecules that we suspect were key to the appearance of life on our planet," he concluded.

Carboxylic acids are a type of organic compound characterized by a carbon (C) atom doubly bonded to an oxygen (O) atom and singly bonded to a hydroxyl group (―OH). Carbonic acid in particular is formed when CO2 is dissolved in water, meaning that it is present in increased concentrations in our seas due to CO2 in the atmosphere.

Many theories as to how life on Earth evolved suggest that primitive life may have emerged from a primordial soup of chemicals when our planet was very young. Some have suggested that these chemicals, including carboxylic acids, may have arrived on Earth from space, traveling via comets and meteorites to the forming planet.

Carbonic acid has been previously detected on other astronomical bodies, including the icy moons of Jupiter, in some meteorites and comets, and even on Mars and Mercury, but until now, has not been seen in interstellar space.

The authors explained that the discovery of these more complex molecules in the interstellar medium may reveal clues about the origins of our planet and the life upon it.

"The presence of prebiotic COMs within extraterrestrial material thus firmly suggests the existence of carboxylic acids of increasing complexity in the ISM (interstellar medium), including amino acid–related species. Within this context, considerable efforts have been devoted to hunting for other acids, such as propenoic or acrylic acid, propanoic acid, cyanoacetic acid, glycolic acid, hydantoic acid, and glycine, whose identification in the [interstellar medium] remains elusive."

[inbetweenimperfectmusings]

I can still hear your mouth

Form the word ‘colourless’

And remnants of my 15 year old self

Within me shiver.

Somehow, I still feel it.

It’s been years since I last dreamed about you but

Trust me,

The images are still as clear as crystal 

Copper Sulfate solution,

Still tinged with the feeling of

A perfect titration,

Still the colour of phenolphthalein 

After one,

Faded from rough at 14,

To perfect at 18,

3 concordant results

Without any spills,

Read at eye level,

Without any lies,

One handed,

Without you to witness.

Did you mark my final paper?

Did you whisper well done under your breath?

Did the 90% staring back at you will you to write it,

Green on the front,

In spite of the number without a name,

To a girl who’ll never get the paper back?

Did you recognise my handwriting

Which still mimics yours,

I’m still stained like a well used results table

To the point where the pencil is smudged,

Still feel shame that rises in the back of my throat

Smelling like Hydrogen Sulfide,

At the thought of walking slower

Than the Haber Process without iron

Just to catch your face in your window,

And I haven’t put on a lab coat that smells like propanoic acid

Instead of cadavers

In over 3 years now,

But sometimes I remember the way you held your hands behind your back,

That you cracked exactly 3 jokes in the 3 years you taught me

And I remember every single word of them,

That you were the first time I blushed,

And I was the first one to defend you

On the basis that you were shy. 

It happens when I read your signature in my year book,

Read what you wrote,

‘You make it look easy’.

It was easy.

I loved it.

The things you love are always easy.

So it hurts that it was easy for you to remember my face after two years

But not the other girls after 6 months,

That it was easy for you to go on

And on

About how brilliant I was in front of my mother

But struggled to say ‘Well Done’

To me.

I hate that it is so easy for me to remember

That infatuation feels like

Burning lithium chloride

In a classroom that you darkened,

Staring at the splint

In the centre of the flame

Knowing it was my heart,

Not blinking but only seeing

The glow of childish joy in your eyes

Reflecting every colour of the flame test,

Watching us all love like you do

While I was there thinking

Of how I loved you.

[nineherbscharm]

ibuprofen truly is a girl's best friend tho. thank u miss (rs)-2-(4-(2-methylpropyl)phenyl)propanoic acid for everything u do.

[toklabou]

浅井ゲルマニウム研究所の安積さんたちとの共著の論文が International Journal of Molecular Science オンラインで公開されました。

[jackhkeynes]

23rd Lexember

taus "rate"

taus /toz/ [toz] - rate, speed, the rapidity at which some process takes place; - value, worth, the quality which renders someone or something desirable or valuable; - (rare) price, cost, the monetary quantity needed to pruchase an item

Etymology: from Old Boral taus "tax, price", deverbal of taussar "to impose a tax on" borrowed from Old French and reflecting Latin taxō "I handle, charge, appraise, reckon" (compare modern French taux "level, amount, quantity" with an etymological respelling).

Taus gran alcot es y molin rouð faint la? /toz gran alˈkɔt ɛz i moˈlɪn ruθ fent la/ [toz gʀan ɐˈgɔt ɪz i mʊˈlɪn ʀuh fen la] rate big how.much be.3s 3s mill wheel make-p.prs there At what rate does the factory make wheels?

---

excerpt from the introduction of Modern Developments in Benjamine Detaxion [Aromatic Synthesis], a 1942 quire written by alchemist Ferris Bewly through the Conster Health Edifice and intended to provide a reference on the recent synthesis of various new substances and medicines around the world.

…Jawan frankincense.

The first major section of this work will cover those hebetant substances [painkillers] which have come out of workshops globally over the last two decades. The sterling example is undoubtedly cozebdone-diamaschal benjamine (CD) [1], sold under various names and perhaps most familiar to Markland as the coveted 'Tommy pills', is a product of collaboration between the Branwen Sanatory in New Leudong and the University of Rimack in Tavance [2] to find hebetants with faster action and fewer adversions.

Comprising (as the longform name implies) branches of cozebdone oil and maschal [3] in opposed position, the substance was first synthesised in 1932 and has already surpassed salix-derivative pills [4] in annual sales everywhere from Sangathy to Adighe [5]. This is due to the former's greater efficacy in relieving pain, which finds it more widely used than the previous bevy of remedies which may merely help to reduce symptoms of fever.

In sufficiently high concentrations CD has also been demonstrated to function in unguento, although the inefficiency and commodity of this…

---

[1] Here the longform unambiguous name for ibuprofen. [2] Polities in southeastern Chrysia [Australia] and northwestern Cappatia [South America]. [2] Or as we would call them, isobutane (2-methylpropane) and propionic (propanoic) acid. [4] For example, aspirin. [5] Polities in far-inland Mendeva [North America] and the Caucasus.

[chemwhat]

Phosphatidylserine CAS#: 51446-62-9

Names & Identifiers Product Name Phosphatidylserine Synonyms 1,2-Distearoyl phosphatidyl serine;1,2-Distearoyl-sn-3-glycerophosphoserine;Distearoylphosphatidylserine;PHOSPHATIDYLCHOLINE(SOY)(RG);(2S)-2-Amino-3-((((R)-2,3-bis(stearoyloxy)propoxy)-(hydroxy)phosphoryl)oxy)propanoic acid;1,2-Distearoyl-sn-glycero-3-phosphatidylserine;L-ALPHA-PHOSPHATIDYLSERINES, BRAIN CAS Registry Number 51446-62-9 Molecular Formula C42H82NO10P Molecular Weight 792.081 EINECS Other Registry Numbers IUPA Names, InChI, InChI Key, Canonical SMILES, etc.: IUPA Names, InChI, InChI Key, Canonical SMILES, etc. Chemical & Physical Properties form Liquid Color Yellow Safety & Hazards(Codes & Phrases) More Safety & Hazards From PubChem Signal, GHS Hazard Statements, Precautionary Statement Codes, etc. Literature Literature on PubChem Synthesis References, Metabolite References, etc. Patents Patents on PubChem Related Patents Of This Product Transportation, Storage & Usage Transportation No Information Storage No Information Usage No Information Spectral Properties No Information Read the full article

[moleculardepot]

1-Methyl-D-tryptophan

1-Methyl-D-tryptophan Catalog number: B2016131 Lot number: Batch Dependent Expiration Date: Batch dependent Amount: 50 mg Molecular Weight or Concentration: 218.25 Supplied as: Powder Applications: a molecular tool for various biochemical applications Storage: RT, Dry Keywords: (2R)-2-Amino-3-(1-methyl-1H-indol-3-yl)propanoic acid, D-(+)-1-Methyltryptophan Grade: Biotechnology grade. All products…

[china-cryogenic-tanks]

ethylene gas tank

Ethylene C2H4 Gas Suppliers

supply C2H4 Gas Purity: 99.5% or 99.95% Ethylene Cylinder: 40-50L,Valve: According to customer need Produced by passing ethyl alcohol vapours over dehydrating catalysts at 360-470 °C. Be produced by the pyrolysis of ethane.

Category: Ethylene GasTag: Ethylene C2H4 Gas

Description

C2H4 GAS suppliers

DSW Gas is an environmentally intensive integrated gas supplier specializing in gas research and development, production, sales, and service. Founded in 1999, DSW has more than 100 kinds of products in three categories: specialty gas, bulk gas, and standard gas, providing comprehensive and systematic gas solutions for more than 5000 clients, exporting to Thailand, Vietnam, Malaysia, and other countries.

C2H4 GAS

GasEthyleneChemical FormulaC2H4Einecs:200-815-3Molecular Weight:28.054CAS:74-85-1Flammability range in air, [% volume]:2.7-36.0Boiling Point:at 1.013 bar [℃]-103.68at 14.5 psi, [℉]-154.60Density:at 1.013 bar,15℃, [kg/m³]1.194at 1 atm., 70℉, [lb/ft³]0.073

Process

Ethylene is produced by passing ethyl alcohol vapors over dehydrating catalysts at 360-470 °C. The pyrolysis of ethane may also produce it. The cracking of petroleum is another source.

Applications

Ethylene is the starting material for several industrial syntheses. It is employed as an intermediate in the chemical industry and for the production of plastics. Ethylene C2H4 Gas is employed for the production of: acetaldehyde acetic acid chloroethane chloroethene (vinyl chloride) dichloroethane 1,1-dichloroethene (vinylidene chloride) epoxyethane (ethylene oxide) ethanediol (ethylene glycol) ethanol ethoxyethane ethylbenzene phenylephrine (styrene) polychloroethene (polyvinyl chloride) polyethylene propanoic acid tetraethyl lead trichloroethane

Buy Ethylene Gas We offer gases in a variety of purities and concentrations, including ethylene, acetone, ethylene, liquefied ethylene, ethylene, Ne Kr Gas, C2H2 Gas, Nitric Oxide Gas, Solid Carbon Dioxide, N2O gas, H2 PH3 Gas.

[starsincline]

I swear to god chem pract made me nearly kill myself I couldn't figure out q2 and I was freaking out and then I came up with the answer at 8pm and almost died. (forgot to add the 0.7 and was wondering why I had 9 grams of copper) and then I spilled the stupid hcl on my hand and now I have some weird burn thing. also forgot to add boiling stones and water bath for the propanoic acid

[whats-in-a-sentence]

The values of Ka and pKa for some typical weak acids are given in table 11.4.

"Chemistry" 2e - Blackman, A., Bottle, S., Schmid, S., Mocerino, M., Wille, U.

[tzatziki-boy]

I can't wait for my doctor's appointment tomorrow. 🤍 I need to make copies of some documents later and cook lunch too, maybe pasta. 🤍 I'll edit my CV and submit it to my friend. Ibuprofen save me. Ibuprofen = C13H18O2 = (RS)-2-(4-(2-Methylpropyl)phenyl)propanoic acid.

[chemanalystdata]

Sodium Propionate Market Size, Growth | Regional Analysis and Forecast to 2030 | ChemAnalyst

According to ChemAnalyst report, “Sodium Propionate Market Analysis: Plant Capacity, Production, Operating Efficiency, Demand & Supply, End Use, Distribution Channel, Regional Demand, 2015-2030”, Sodium Propionate market grew at a considerable CAGR of 4.01% in the last five years and is anticipated to achieve a healthy CAGR during the forecast period 2020-2030. An exponential surge in the demand of Sodium Propionate as food preservatives by the food and beverage industry is likely to boost the growth of global Sodium Propionate market in upcoming years. The production of Sodium Propionate is highly associated with the safety standards on human health before it can be introduced in the market which further enhances the compliance standards.

Sodium Propionate (C3H5NaO) also known as Sodium propanoate is an organic salt of propionic acid that comprises of equal numbers of sodium and propionate ions. It plays a huge role as an antifungal drug and a food preservative. It basically inhibits the growth of lactic acid bacteria thus preventing the food from getting rotten. Sodium Propionate is synthesized chemically by neutralizing propionic acid with sodium hydroxide. Due to its properties, it is extensively used in baked items, processed meats, dairy products, soft drinks, alcoholic beverages, and others. Surging demand for sodium propionate from food and pharmaceutical industries is driving the global market of Sodium Propionate across the globe. According to the US Food and Drug Administration (FDA), it is recognized as a safe food ingredient by FDA.

Read Full Report Here: https://www.chemanalyst.com/industry-report/sodium-propionate-market-602

The demand for Sodium Propionate from the food industry is expected to rise in upcoming years, due to ever-changing consumer preference and taste for enhanced flavors and shelf life of baked and frozen foods. In the medical and healthcare sector, rising demand of Sodium Propionate for the production of medical drugs to treat fungal and bacterial infections is likely to augment the growth of Sodium Propionate market over the next few years. Furthermore, increased use of Sodium Propionate in cosmetics, personal care, agrochemical and other industries is expected to boost the global sodium propionate market until 2030. 

Global Sodium Propionate Market is segmented based on form, application, distribution channel and region. Based on different forms, the Global Sodium Propionate market is segmented into granules and Powders. Among which, the granules segment is holding a larger share in the global market. On the basis of application, the market is segregated into Cosmetics and Personal Care, Agrochemicals, Food and Beverage, Animal Feed, Pharmaceuticals, and Others. The Food and beverage segment dominates the global Sodium Propionate market as it is widely used as a food additive and preservative in bakery products like blue cheese, breads, buns, cakes et., cured; meat products, dried meat and other processed foods.

In the first half of 2020, several industries witnessed an unprecedented fall due to the lockdowns and restrictions by the government in order to stop the coronavirus from spreading. However, there was a boost in the demand for packaged and baked goods pulled by sudden outbreak of COVID-19 across the globe is expected to have a positive impact on the demand of Sodium Propionate as it is utilized in numerous products. Also, pharmaceutical and food industries fuelled the demand of Sodium Propionate during the covid times.

Region wise, North America Region dominated the global Sodium Propionate market in 2020, due to the presence of various leading producers in the region as well as exponential demand for baked products in countries like US that would further drive the Sodium Propionate market during coming years. Followed by Europe, where the demand of Sodium Propionate from food preservatives and food additives sector was observed in countries include France, United Kingdom and others. Furthermore, Asia Pacific region is expected to dominate the global Sodium Propionate market in the next ten years due to the expansion of industries and capacities.

Request Sample Form: Sodium Propionate Market Report

Some of the major players operating in the global Sodium Propionate market are Dr. Paul Lohmann GmbH & Co. KGaA, Niacet Corporation, Macco Organiques Inc., Fine organic industries, Ltd, Foodchem International, Prathista Industries Ltd., DR. Paul Lohmann GmbH KG, Sigma-Aldrich, Inc., Rishi chemical works Pvt. Ltd., Titan biotech Limited, Toronto Research Chemicals Inc., Krishna chemicals and others.

“Rising demand of Sodium Propionate by the food and beverage industry in order to provide protection, flavor and shelf life to frozen, baked and processed food is anticipated to dominate the Sodium Propionate market across the globe over the next ten years. Bakery and confectionary industry are dominating the Sodium Propionate market and is expected to maintain its dominance in the future as well. Increasing demand of Sodium Propionate by the pharmaceutical industry for the treatments of various infections is also likely to provide opportunities for the growth of the market.” said Mr. Karan Chechi, Research Director with TechSci Research, a research-based management consulting firm promoting ChemAnalyst worldwide.

About Us: 

ChemAnalyst is a subsidiary of Techsci Research, which was established in 2008, and has been providing exceptional management consulting to its clients across the globe for over a decade now. For the past four years, ChemAnalyst has been a prominent provider of Chemical commodity prices in more than 15 countries. We are a team of more than 100 Chemical Analysts who are committed to provide in-depth market insights and real-time price movement for 300+ chemical and petrochemical products. ChemAnalyst has reverberated as a preferred pricing supplier among Procurement managers and Strategy professionals worldwide. On our platform, we provide an algorithm-based subscription where users can track and compare years of historical data and prices based on grades and incoterms (CIF, CFR, FOB, & EX-Works) in just one go.

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[happy-smile-flowers]

Targeting chemical synthesis through a single ibuprofen

Today we will talk about the synthesis and mechanism of action of Ibuprofen, an evergreen drug!

As an essential part of the development of the pharmaceutical industry, the chemical synthesis of drugs is the primary source of candidate drugs. It is also a high-input, high-output, and high-efficiency work.

The research and development directions of chemically synthesized drugs mainly include the following:

Research and development of new chemical entity drugs;

Create "Me-too" new drugs—research and development of imitative new drugs;

Further research and development of known drugs;

Pharmaceutical research and development of existing drugs;

Research on new uses of existing drugs;

Avoiding patented technology.

Medicilon is proud of our extensive expertise in synthetic organic chemistry, providing chemical synthesis services. Medicilon's synthetic chemistry team can independently design synthesis pathways and complex compound treatments, which is key to helping accelerate our clients' drug discovery.

Recently, Ibuprofen has been hard to find and has become a hard currency.

1.Ibuprofen

Ibuprofen, molecular formula C13H18O2, chemical name 2-(4-Isobutylphenyl)propanoic acid. Ibuprofen is a commonly used non-steroidal anti-inflammatory drug (NSAID), which produces analgesic and anti-inflammatory effects by inhibiting cyclooxygenase and reducing prostaglandin synthesis; it acts as an antipyretic agent through the hypothalamic thermoregulatory center. Ibuprofen is usually well tolerated and does not usually cause clinically significant severe acute liver injury.

2. Ibuprofen indications

Oral administration: For the relief of mild to moderate pain such as arthralgia, neuralgia, muscle pain, migraine, headache, dysmenorrhea, and toothache, and also for the relief of fever due to the common cold or influenza. Injectable administration: for antipyretic and analgesic treatment: for mild to moderate pain, as an adjunct to opioid analgesics for moderate to severe pain; antipyretic therapy of fever.

3. Ibuprofen mechanism of action

Ibuprofen is a diastereomeric chiral drug containing R- and S-ibuprofen. Pharmacokinetic studies have shown that most of the pharmacologically active form of the drug is contributed by its S-enantiomer, as it inhibits prostaglandin synthesis. In the early to mid-1970s, the first report of the conversion of the inactive R-enantiomer to the active S-enantiomer by unidirectional enzymatic conversion was made. Approximately 40-60% of the R-enantiomer is metabolized in the liver to the S-ibuprofen form. Its anti-inflammatory effect is due to the inhibitory activity of S-ibuprofen on cyclooxygenase (COX), which is responsible for prostaglandin synthesis and plays a vital role in neuronal death mediated by an increased inflammatory response. Ibuprofen inhibits COX, reduces nitric oxide (NO) production, and activates peroxisome proliferator-activated receptor-γ (PPAR-γ).

4. Ibuprofen Chemical Synthesis

Ibuprofen was first patented by Boots Pure Chemical Company in 1961 and approved as an over-the-counter drug in 1984. Since its introduction, Ibuprofen has been marketed under several brands, including Advil® and Motrin®. The synthesis of ibuprofen begins with isobutyl benzene. The synthesis process includes Friedel-Crafts acylation, reduction, chloride substitution, and the Grignard reaction. The products of each step were then analyzed by IR and 1 H NMR spectroscopy, and the final product was confirmed by melting point determination analysis. In 1992, BHC developed a new sustainable synthesis method that cut the synthesis steps in half. The first step uses anhydrous hydrogen fluoride as the catalyst and solvent, which is then recycled and reused. In addition, the real highlight behind the BHC method was the reduction of unwanted waste and impurities, generating only one water molecule as a by-product. This led to a genuinely green synthesis.

In 2009, Andrew R. Bogdan et al. of Florida State University used a microreactor to synthesize Ibuprofen. Microreactors are safer, more efficient, and more selective chemical transformations in microchannels or narrow bore tubes. Using isobutyl benzene and propionic acid as feedstock, the total reaction time was approximately 10 minutes, with a crude yield of 68% and a yield of 51% after recrystallization (99% purity by GC and NMR analysis).

In 2014, David R. Snead, Ph.D., and Professor Timothy F. Jamison of Massachusetts Institute of Technology (MIT) performed a multi-step sequential reaction using isobutylene and propionyl chloride as feedstocks. Ibuprofen was assembled from its basic structural units in three minutes, with an average yield of over 90% at each step from the starting material to the target compound.

References

[1] Ashish Singh et al. Neuroinflammatory responses in Parkinson's disease: relevance of Ibuprofen in therapeutics. Inflammopharmacology. 2021 Feb;29(1):5-14. DOI: 10.1007/s10787-020-00764-w. [2] Mark A. Murphy. Early Industrial Roots of Green Chemistry and the BHC Ibuprofen process invention's history and quality connection. Foundations of Chemistry volume 20, pages 121-165 (2018). [3] Andrew R Bogdan, et al. The continuous-flow synthesis of Ibuprofen. Angew Chem Int Ed Engl. 2009;48(45):8547-50. doi: 10.1002/anie.200903055. [4] David R Snead et al. A three-minute synthesis and purification of Ibuprofen: pushing the limits of continuous-flow processing. Angew Chem Int Ed Engl. 2015 Jan 12;54(3):983-7. DOI:

[wwwsarms4musclecom]

cas: 328086-60-8  2-oxo-3-Pyrrolidinepropanoic acid methyl ester CBNumber: CB92694668 Chemical Name: Methyl (S)-2-(Boc-amino)-3-[(S)-2-oxo-3-pyrrolidinyl]propanoate Molecular Formula: C13H22N2O5 Formula Weight: 286.33 CAS No.: 328086-60-8