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hrpdfrisco · 2 years
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Pregnancy Doctors Near me
When you’re expecting a child, you need experts on your team to help guide you every step of the way. At High Risk Pregnancy Doctors in Frisco, Texas, Maternal-Fetal Medicine specialist Violetta Lozovyy, MD, and her team provide high-quality care with a hands-on approach.
High-Risk Pregnancy Doctors practice is dedicated to the highly-accessible, patient-centered experience. The team understands that whether you are low risk, the low risk that can become a high risk, or have prior risks associated with a high risk pregnancy, you need expert care. As specialists in Maternal-Fetal Medicine, High Risk Pregnancy Doctors offer a wide range of services including extended hours for your flexibility to access the care you need.
Preparedness is essential when you’re expecting a child – make sure you have the best team behind you to help you succeed. Call High Risk Pregnancy Doctors to make an appointment or book one online today.
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torchickentacos · 1 year
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oh my god i am so crampy that i cannot move right now so fuck it. ag watch through is happening. will be tagging it with #ag watchthrough if anyone wants to mute that. one post with all my thoughts per episode .I did this once before but couldn't commit, but I'll try again. I need something to focus on right now, but not something I need to THINK about and this feels like a compromise. The goal will be one episode a day, counting queueing posts. Will I regret this a third of the way through season one? probably but so it goes.
#long tags. accidental methodology infodump#my therapist wants me to schedule time to relax so i can do this and say i set aside at least twenty minutes a day#genuinely need to get the cramps sorted out before i stop online classes though#i cannot function out in society like this#doctors were like 'yeah sounds like endo. no we won't check.'#like okay :) thanks :))) 👍#would love to see more studies and info on the link between endo and eds#bc there are heavy anecdotal links#it seems like a really common comorbidity#i found one study that showed a link but it was from 1995 and was of 41 women#and it wouldn't let me in to actually read over the study and methods. it was author info and the abstract only#so idk how much was self reporting or what#and it looked like a voluntary selection which skews stuff BUT I COULDN'T GET IN TO LOOK#bc like ok here's the thing#Do I think there is a link given how heavily people report overlap and given the width of eds comorbidities? yes#but in a study where people volunteered for it#if they saw 'eds/gynecological disorder study applicants open'#then people who experience eds AND gynecological disorders will likely be the ones who apply for it#so any link might be misrepresented as having a larger correlation than it actually does#GOD I would love to get into this kinda stuff for a career if i could only do math#and like it gave numbers but no baseline#it said that the correlation was certain percentages but did not give percentages to compare it to for the general population in the abstra#and numbers like that are important due to their context and can be meaningless or innacurate without it#like. COMPLETELY RANDOM AND INNACURATE example. numbers are bullshitted#you can say that people should avoid traveling in cars because five percent of car crashes are fatal#that sounds worrying doesn't it? you can accept the 'thesis' as fact based on that statistic. it sounds reasonable.#and 70 percent result in up to severe injury#but you need the context to look at how many people use cars every single day and don't get in crashes#you need that larger context to it because cars ARE safe actually#and also think. what does the statistic count as 'injury'?
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uniqueeval · 28 days
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Can forgotten rubella children of the ’60s hold clue for Zika babies?
Story highlights Babies with multiple birth defects were born to US women infected with the rubella virus in the 1960s What these families have needed may signal what’s in store for Zika babies Brooklyn, New York CNN  —  One side of the bedroom is an explosion of pink, from the hair accessories and dangling trinkets to the stuffed animals and laundry hamper. The other, starting with the fuzzy…
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omegahospitals4 · 1 month
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Top Gynaecologists & Obstetricians in Hyderabad | Omega Hospitals
Trust Omega Hospitals top Gynaecology Doctors in Hyderabad for advanced, reliable gynecological treatments and surgeries with cutting-edge care.
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aingopharma · 1 month
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Dydrogesterone Tablet IP 10 mg is a synthetic hormone widely used in hormone replacement therapy (HRT) and other gynecological treatments. This medication mimics the effects of the natural hormone progesterone, playing a crucial role in regulating menstrual cycles and maintaining pregnancy. In this article, we’ll dive into the uses, benefits, dosage guidelines, and potential side effects of Dydrogesterone Tablet IP 10 mg. Whether you’re dealing with menstrual irregularities, endometriosis, or infertility issues, understanding how this medication works can help you make informed decisions about your reproductive health.
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nurvinaari1 · 3 months
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Tips By Gynecologist in Manpada Thane Signs Labor Is Near
Key signs labor might be close: 1. Pelvic Pressure: Baby moving downward. 2. Bloody Show: Mucus with blood. 3. Braxton Hicks: Intensifying contractions. 4. Water Breaking: Ruptured sac. 5. Lightening: Baby dropping into pelvis. Be prepared and consult your doctor! #maternitycareinthane #gynecologistinthane #gynecologistinvartaknagar
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ayurvedicguru · 3 months
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Best Ayurveda Treatment for Gynecological Disorders
Gynecological disorders encompass a range of issues affecting the female reproductive system, including menstrual irregularities, infertility, polycystic ovary syndrome (PCOS), and menopausal symptoms. These conditions can significantly impact a woman’s health and quality of life. The Best Ayurveda Treatment for Gynecological Disorders offers a natural, holistic approach to managing and alleviating these issues, focusing on restoring balance and promoting overall well-being.
Understanding Gynecological Disorders in Ayurveda
Ayurveda, the ancient Indian system of medicine, views gynecological disorders as imbalances in the body’s doshas—Vata, Pitta, and Kapha. The Best Ayurveda Treatment for Gynecological Disorders aims to correct these imbalances through personalized treatments that include herbal remedies, dietary modifications, lifestyle changes, and detoxification therapies.
Common Gynecological Disorders and Ayurvedic Approaches
Menstrual Irregularities: Issues such as irregular periods, heavy bleeding, and painful menstruation can be effectively managed with the Best Ayurveda Treatment for Gynecological Disorders. Key treatments include:
Ashoka (Saraca asoca): Known for its ability to regulate menstrual cycles and reduce heavy bleeding.
Lodhra (Symplocos racemosa): Helps in managing excessive menstrual bleeding and promoting uterine health.
Shatavari (Asparagus racemosus): Balances hormones and supports reproductive health.
Polycystic Ovary Syndrome (PCOS): PCOS is characterized by hormonal imbalances and metabolic issues. The Best Ayurveda Treatment for Gynecological Disorders for PCOS includes:
Cinnamon (Cinnamomum verum): Improves insulin sensitivity and regulates menstrual cycles.
Neem (Azadirachta indica): Helps in detoxifying the body and reducing insulin resistance.
Turmeric (Curcuma longa): Anti-inflammatory and hormone-balancing properties aid in managing PCOS symptoms.
Infertility: Ayurveda offers effective treatments for infertility by enhancing reproductive health and balancing hormones. The Best Ayurveda Treatment for Gynecological Disorders for infertility involves:
Shatavari (Asparagus racemosus): Enhances fertility and promotes overall reproductive health.
Ashwagandha (Withania somnifera): Reduces stress and balances hormones.
Gokshura (Tribulus terrestris): Improves fertility and supports reproductive health.
Menopausal Symptoms: Menopause brings various symptoms like hot flashes, mood swings, and sleep disturbances. The Best Ayurveda Treatment for Gynecological Disorders for menopause includes:
Licorice (Glycyrrhiza glabra): Helps in balancing hormones and alleviating hot flashes.
Brahmi (Bacopa monnieri): Reduces stress and improves cognitive function.
Guggulu (Commiphora mukul): Supports joint health and helps in managing weight gain during menopause.
Benefits of Best Ayurveda Treatment for Gynecological Disorders
The Best Ayurveda Treatment for Gynecological Disorders provides numerous benefits, promoting overall health and well-being:
Natural and Safe: Utilizes natural herbs and treatments with minimal side effects.
Holistic Approach: Addresses the root cause of gynecological issues rather than just the symptoms.
Hormonal Balance: Restores natural hormonal balance, improving reproductive health.
Reduced Symptoms: Effectively alleviates symptoms of gynecological disorders.
Enhanced Quality of Life: Promotes overall health and well-being through balanced living.
Personalized Ayurvedic Treatment
At Adyant Ayurveda, we understand that each woman’s experience with gynecological disorders is unique. Our experienced practitioners provide personalized treatments that incorporate the Best Ayurveda Treatment for Gynecological Disorders, tailoring the therapies to meet your specific needs. We combine these treatments with dietary advice, herbal supplements, and lifestyle recommendations to ensure a comprehensive approach to managing gynecological disorders.
Conclusion
The Best Ayurveda Treatment for Gynecological Disorders offers a natural, holistic, and effective way to manage a wide range of gynecological issues. By focusing on restoring dosha balance, eliminating toxins, and promoting reproductive health, Ayurveda provides a comprehensive solution for women’s health. If you are seeking a sustainable and natural way to manage gynecological disorders, consider consulting the experts at Adyant Ayurveda. Our personalized treatments can help you achieve better health and improve your quality of life. Visit Adyant Ayurveda today to start your journey towards optimal gynecological health.
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nirmalayurveda · 4 months
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Ayurvedic Lifestyle Changes For Better Metabolic Health
Nirmal Ayurved specializes in promoting better metabolic health through tailored Ayurvedic lifestyle changes. By integrating ancient Ayurvedic principles with modern wellness practices, Nirmal Ayurved offers personalized guidance to improve digestion, boost energy, and enhance overall well-being. Their holistic approach includes dietary recommendations, herbal supplements, detoxification therapies, and stress management techniques, all designed to balance the body's doshas and optimize metabolic function. Committed to natural and sustainable health solutions, Nirmal Ayurved empowers individuals to achieve lasting vitality and harmony in their lives.
Read more:-
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helpfulcontent · 7 months
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Nurturing Women's Health Unveiling the Best Ayurvedic Treatment for Gynecological Disorders
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In the realm of holistic healthcare, Ayurveda offers profound solutions for women's health concerns. Explore the transformative power of Ayurvedic therapies as we delve into the Best Ayurvedic Treatment for Gynecological Disorders and other prevalent health issues such as hypertension, infertility, and weight loss.
Addressing Gynecological Concerns with Ayurveda
For women grappling with gynecological disorders, finding effective and holistic treatments is paramount. At our Ayurvedic center, we offer the Best Ayurvedic Treatment for Gynecological Disorders, personalized to address specific concerns such as menstrual irregularities, hormonal imbalances, and reproductive health issues. Our experienced Ayurvedic practitioners utilize a blend of herbal remedies, dietary modifications, and lifestyle interventions to restore balance and vitality to the female reproductive system.
Managing Hypertension Naturally with Ayurveda
Hypertension, or high blood pressure, is a common health condition that can have serious implications if left untreated. Our Ayurvedic experts provide the Best Ayurvedic Treatment for Hypertension, focusing on lifestyle modifications, stress management techniques, and herbal formulations to regulate blood pressure levels naturally. By addressing the root cause of hypertension and promoting overall well-being, we help patients achieve long-term cardiovascular health.
Fertility Enhancement through Ayurveda
Infertility can be a challenging and emotionally taxing journey for couples longing to conceive. Our Ayurvedic fertility specialists offer the Best Ayurvedic Treatment for Infertility, utilizing ancient healing techniques to optimize reproductive health and enhance fertility. Through personalized treatment plans, including Panchakarma therapies, herbal supplements, and fertility-enhancing diet and lifestyle recommendations, we support couples in their quest for parenthood.
Holistic Weight Management Solutions
Obesity and weight-related health issues are prevalent concerns in modern society. Our Ayurvedic approach to weight management goes beyond calorie counting and restrictive diets. We provide the Best Ayurvedic Treatment for Weight Loss, focusing on holistic lifestyle modifications, detoxification therapies, and metabolism-boosting herbal remedies to achieve sustainable weight loss and promote overall health and well-being.
Conclusion: Embracing Holistic Healing
In conclusion, Ayurveda offers comprehensive solutions for women's health issues, hypertension, infertility, and weight management. Our Ayurvedic treatments address the root cause of health imbalances, promoting natural healing and rejuvenation. Experience the transformative power of Ayurveda at our center, where we offer the Best Ayurvedic Treatment for a range of health concerns, empowering you to embrace holistic well-being and vitality.
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eva1casmoclinic · 9 months
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Women have problems with intimacy, just like men have, and these issues should be addressed. Orgasmic disorder in women is defined as the inability or delay of a woman to experience a sexual climax (orgasm), even when sexual stimulation is sufficient.
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hrpdfrisco · 2 years
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Best pregnancy clinic near me
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informationtips · 10 months
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Harmony and Healing: Ayurvedic Treatment for Gynecological Disorders
Explore the holistic world of Ayurveda to address gynecological disorders naturally. Uncover time-honored remedies, personalized approaches, and ancient wisdom tailored to restore balance and well-being. Discover the transformative power of Ayurvedic treatments in promoting women's health, offering a gentle and effective path to renewed vitality and harmony.
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drdeepaligynecologist · 10 months
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Dr. Deepali - Best Gynecologist In Jaipur
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With the myriad of options available in the healthcare industry, finding a gynecologist who not only possesses exceptional medical expertise but also exudes empathy and understanding can be a daunting task. Dr. Deepali, the esteemed gynecologist in Jaipur, seamlessly embodies these qualities, providing comprehensive care tailored to each patient's unique needs. Her unwavering commitment to women's health and well-being has solidified her position as a beacon of reliability and compassion in the medical community.
Qualifications and Expertise
Dr. Deepali journey to becoming the best gynecologist in Jaipur is marked by her extensive qualifications and unwavering dedication to her field. Holding a prestigious medical degree from a renowned institution and backed by years of hands-on experience, she has honed her skills to offer the highest standard of care to her patients. Dr. Deepali  Best Gynecologist Doctor in Jaipur expertise spans an array of gynecological concerns, including reproductive health, menstrual disorders, menopause management, and fertility issues, positioning her as a trusted advisor for women of all ages.
Her commitment to staying abreast of the latest advancements in gynecological care is evident in her active participation in professional development programs and her incorporation of cutting-edge techniques into her practice. Dr. Deepali patients benefit from her comprehensive knowledge and innovative approach, ensuring that they receive the best possible care.
Services Offered
Dr. Deepali practice encompasses a wide range of services designed to address the diverse needs of women at every stage of life. From routine gynecological examinations and preventive care to advanced treatments for complex conditions, her practice is a one-stop destination for comprehensive women's healthcare. She offers personalized counseling and support for fertility concerns, prenatal care, childbirth services, and postpartum care, ensuring that her patients receive holistic care throughout their reproductive journey.
Additionally, Dr. Deepali  Lady Gynecologist Doctor in Jaipur provides specialized care for gynecological issues such as endometriosis, polycystic ovary syndrome (PCOS), urinary incontinence, and pelvic organ prolapse, offering tailored treatment plans to alleviate discomfort and improve overall quality of life. Her commitment to providing a comprehensive suite of services underscores her dedication to empowering women to prioritize their health and well-being.
Patient Testimonials and Success Stories
The hallmark of Dr. Deepali female gynecologist in Jaipur practice lies in the countless success stories and glowing testimonials from her patients, each serving as a testament to her unwavering commitment to excellence. Patients consistently praise her warm demeanor, compassionate approach, and ability to instill confidence and trust in their healthcare journey. Many attribute their successful pregnancies, effective management of gynecological conditions, and overall well-being to Dr. Deepali Best Gynecologist Doctor in pratap nagar personalized care and unwavering support.
Importance of Regular Gynecological Check-ups
Regular  Top gynecologist in jaipurcheck-ups are fundamental to maintaining optimal health and detecting potential concerns at an early stage. Dr. Deepali emphasizes the significance of routine screenings and examinations as a proactive measure to prevent and address gynecological issues before they escalate. By fostering open communication and cultivating a safe space for her patients, she encourages them to prioritize their well-being and seek regular check-ups as a cornerstone of their overall health maintenance.
Addressing Common Women's Health Issues
Dr. Deepali expertise Best Obstetrician in Jaipur  extends beyond routine gynecological care to encompass the comprehensive management of common women's health issues. She provides personalized solutions for menstrual irregularities, hormonal imbalances, sexual health concerns, and menopausal symptoms, ensuring that her patients receive tailored care to address their specific needs. Her holistic approach considers the physical, emotional, and psychological aspects of women's health, empowering her patients to achieve optimal well-being.
Pregnancy Care and Childbirth Services
Guiding women through the transformative journey of pregnancy and childbirth, Dr. Deepali offers comprehensive prenatal care, childbirth planning, and postpartum support. Her nurturing approach and attention to detail ensure that expectant mothers receive personalized care, empowering them to navigate the complexities of pregnancy with confidence and assurance. Dr. Deepali expertise in high-risk pregnancies and her ability to provide compassionate support during labor and delivery have earned her the trust and gratitude of countless mothers. 
OTHER LINKS :
NICU Hospital In Jaipur
PID Treatment in jaipur
Fertility Doctor in Pratap Nagar, Jaipur
Natural Birthing Doctor In jaipur
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infertilityspecialist1 · 11 months
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IVF Centre in Indore - Dr. Heena Agrawal
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Dr. Heena Agrawal has established an outstanding IVF Centre known for its excellence in fertility care. With a dedicated team of experts and facilities, the IVF centre in Indore, led by Dr.Heena Agrawal, provides comprehensive and compassionate care to individuals and couples facing infertility challenges. Dr. Heena Agrawal's commitment to personalized treatment plans and her expertise in assisted reproductive technologies make this IVF Centre a top choice for those seeking fertility solutions.
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zsuuv139 · 1 year
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rare original content time! and its gonna be me venting
cw: weight "management", weight loss and gain, gynecological issues, doctors, the rona
so either this story starts in my childhood: i've always been a fat girl and have recently discovered that it was basically eating for attention, positive or negative, since i also was a glass child.
or this story starts 3 years ago, with the pandemic. where i gained even more weight. but i also met this guy and he and another friend somewhat motivated me to lose a lot of weight (that i was really happy with and i felt better in my body, happier overall due to exercise). and then last february (2022) not only did i hook up with a guy, i also got myself a nice little BV out of it. and ofc the rona. after the rona cleared up, i went to a gyno who also did an ultrasound and found a cyst. i felt my life implode - i had only heard bad stuff about ovarian cysts.
they told me to not do intense workouts and put me on hormonal birth control. i could barely stand on my 2 legs. and i was depressed as hell. gained a lot of it back. got off the birth control because suddenly the cyst was not on my ovary anymore but somehow adjacent to it and hormones dont help anymore. still couldn't work out.
am also supposed to get an mri that either has a 6 month waitlist or a 100+ usd cost - my monthly pay is about 1k usd so i kinda cant afford it.
i recently took steps toward getting the mri - another gyno visit. now i also have a polycystic ovary (just one of the 2. hormone levels still ok - not pcos).
im also currently getting fired/ laid off and at the time of that appointment, i had just found out and was already exhausted because of multiple failed applications. i was certain that the layoff would happen and was looking and interviewing but got no offers.
when i tried to explain my health situation to my doctor, i ended up crying. she was patient, gave me some paper towels to wipe my face and explained how the procedures were gonna go. i liked the experience overall.
i also gained all the weight i had lost back.
docs want to investigate possible insulin resistance - i got my blood drawn and since then i have a bruise where i was stuck. this has not happened ever before, and i did used to get blood tests for a thyroid issue. im now wondering if this is bc im fat.
went to an endocrinologist - thyroid levels not optimal, and potential insulin resistance that i was hoping they could advise me on.
she calls my name. "how's it going with the weight loss?" i remark that not well.
"do you have endometriosis?"
"im not sure. afaik it needs surgery to be diagnosed and i havent had any surgery in that area. but my periods do hurt like hell and get kinda plentiful, so it wouldnt be a shock."
first few questions go normal, i know my meds, doses, diagnoses. she starts talking about weight loss. i just take it in an "ok im not coming back to her" way. then she starts asking about the cyst. i tell her what i know. she asks "but what does the mri say?" "dunno, they have a 6 month waitlist" "and youre not willing to pay for an emergency?"
now, in her pov, this random fat woman starts crying.
in my pov, all my job hunt stress and worries bubble up - im crying as im typing this ffs, and i do have a job offer currently! i recall how, if i qwere to go on unemployment, i would be eligible for 120 usd a month - i couldn't even pay rent with that! i recall how our transfer within the company was treated - we were told there would be opportunities and we will have to apply, then we applied, got little feedback, and as the other project's start date approached, they started pressuring us (most specifically, me) to do our tests asap and i was literally given 20 minutes on the end of a workweek to decide if i wanted to start on the other project on monday. did not go well.
so i just ended up crying - and angry at myself, since earlier i would just be angry if anything happens, and i was used to working with anger, but i dont know how to deal with crying.
she may have acknowledged that i was crying, saying she knows this situation is not easy but i should do everything to get out of it (no shit).
then, sobbing, i explained that the gyno did not say the mri would be urgent, and she did acknowledge the long waitlist.
doctor goes back to weight loss / eating habits. do i eat dairy? dairy is like fertilizer for the cysts, she says. "i don't drink cows milk. i do like yogurts and cheeses tho." "no, you cannot eat cheese".
what the actual fuck is happening?
she asks me to lay down for an ultrasound of my thyroid (to make sure its all good). i explain that its left side was taken out and on the right, there seems to be just a tiny little lump, and im kinda curious if it grew. should i take off my shirt? nah, just pull the neckline apart.
i would have rather taken it off but k.
she acknowledges that the left lobe is indeed not there, and goes to town with the ultrasound ot see whats up on the remaining right half. kinda hurts but whatever. lets just get this over with.
"how much do ypu weigh?"
"honestly, too much rn"
"100 kg?"
"uhm... [i am above that so i say 5 kg less]"
...
"why did they leave the right lobe?"
fuck knows, lady, it was 10 years ago and im not a doctor. i was an entire child, do you think anyone cared to explain the medical decisions? do you think i understood?
"the theory was that they were hoping it would work at least on its own or that it would make up for the left part"
"well that isnt happening"
"i have noticed. but idk if taking it out now would do any good."
"nah"
tells me i can wipe off the gel and calls me back to her desk while she writes up her report.
tells me that i need a nutritionist for the insulin resistance and refers me to a colleague. then gets back on weight loss.
"the small blob on your thyroid would go away if you managed to lose the weight"
"also don't eat bread. don't have more than 2 slices a day" "i already don't eat bread" "then stop eating pasta."
gurl idk how to tell you but pasta and cheese are the only joy left in my life.
"but you have to go to a specialist. no one can do this alone"
idk how to tell you but im not _paying_ for someone to yell at me to lose weight... i know a lot about diets, nutrition, how a meal should look like, calories, intermittent fasting (btw, have you ever had an endocrinologist recommend intermittent fasting? i heard it was bad for your hormones lol), and i don't want to give like 70 usd for a "specialist" to potentially tell me nothing new. is this arrogant? yes. but again im not rich.
is it cheaper than whatever i would need to do if my body continues to deteriorate? idk. i would have to put it on my goddamn credit card tho.
and then i look on the paper she gave me.
she wrote "emotionally-pshychologically unstable" as a symptom. fuck off the entire way.
i left her office. i cried. i cried some more. i complained to my friends. almost lost it when i couldn't attach a lid on an iced coffee and it spilled on me. i didn't tell my parents because i do not trust them with questions regarding my mental health.
and i read her note about our meet again.
she wrote
"antecedent: right lobectomy.
currently right lobe micronodule"
so that's how doctors listen to fat people.
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wheelie-sick · 7 months
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What is Idiopathic Mast Cell Activation Syndrome?
Idiopathic Mast cell activation syndrome (MCAS) is one of several mast cell disorders. MCAS occurs when there are a normal number of mast cells in a person's body but they over-release mast cell mediators causing random allergic reactions in multiple systems of the body. MCAS is incredibly common being present in an estimated 17% of the population.
Symptoms
MCAS symptoms are incredibly varied and always occur in multiple systems of the body. Anaphylaxis is common.
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[ID: A graphic labeled "Some common symptoms of Mast Cell Disease" A graphic of a person standing in the center with multiple organs visible is shown. Around the person are lines pointing to specific areas of the body labeled with the body system and symptoms. Clockwise these read "Neurological headache, brain fog, cognitive dysfunction, anxiety, depression Cutaneous (Skin) flushing of the face/neck/chest, hives, skin rashes, itching with or without rash Cardiovascular light-heartedness, syncope (fainting), rapid heart rate, chest pain, low blood pressure, high blood pressure at the start of a reaction, blood pressure instability Gynecological uterine cramps, bleeding Urinary bladder irritability, frequent voiding Systemic and/or organ specific Anaphylaxis angioedema (swelling) Skeletal bone/muscle pain, osteopenia, osteoporosis Gastrointestinal diarrhea, nausea, vomiting, abdominal pain, bloating, gastroesophageal reflux disease (GERD) Ear/Nose/Throat/Respiratory nasal itching and congestion, throat itching and swelling, wheezing, shortness of breath and more" In the bottom left corner "Symptoms can be sudden and unpredictable in onset learn more at tmsforacure.org"]
MCAS symptoms are specifically not allergies. the reactions may look like allergies but the two are not the same and MCAS is not a condition meaning "many allergies" While MCAS can have some consistent triggers one of the defining features of the disease is that reactions are random and happen unpredictably.
Anaphylactic shock is not a requirement for diagnosis.
Diagnosis
MCAS is diagnosed by an immunologist. It is in part a diagnosis of exclusion and requires ruling out both allergies and systemic mastocytosis as well as other conditions such as certain types of tumors.
Diagnostic criteria for MCAS is debated. Some immunologists follow the symptom-based diagnosis approach in which case the diagnostic criteria are:
Recurring and severe anaphylactic-like episodes that involve more than one organ system
and
Positive response to mast cell stabilizing or mediator medications anaphylaxis-type symptoms
Others follow diagnostic criteria based on laboratory findings. In this case the diagnostic criteria are:
Episodic symptoms consistent with mast cell mediator release affecting two or more organ systems evidenced as follows:
Skin: urticaria, angioedema, flushing
Gastrointestinal: nausea, vomiting, diarrhea, abdominal cramping
Cardiovascular: hypotensive syncope or near syncope, tachycardia
Respiratory: wheezing
Naso-ocular: conjunctival injection, pruritus, nasal stuffiness
and
A decrease in the frequency or severity; or resolution of symptoms with anti-mediator therapy: H1 and H2 histamine receptor antagonists, anti-leukotriene medications (cysLT receptor blockers or 5-LO inhibitor), or mast cell stabilizers (cromolyn sodium)
and
Evidence of an elevation in a validated urinary or serum marker of mast cell activation: Documentation of elevation of the marker above the patient’s baseline during a symptomatic period on at least two occasions; or if baseline tryptase levels are persistently >15ng, documentation of elevation of the tryptase above baseline on one occasion. Total serum tryptase is recommended as the markers of choice; less specific (also from basophils) 24 hour urine histamine metabolites, or 11-beta-prostaglandin F2.
and
Primary (clonal) and secondary disorders of mast cell activation ruled out.
These are not all proposed diagnostic criteria as the subject is heavily debated. Generally, a laboratory-confirmed MCAS diagnosis is considered more legitimate.
Treatment
MCAS is a very treatable condition. Generally treatment follows a path from antihistamines -> mast cell mediators -> biologics.
Epipens are given to MCAS patients with a history of anaphylaxis.
Antihistamines are divided into 2 categories: H1 antagonists and H2 antagonists. These categories are determined based on the histamine receptor each one targets.
H1 antagonists mostly deal with systemic and cutaneous symptoms. H1 antagonists are also further divided into first and second generation antihistamines. first generation antihistamines include diphenhydramine (Benadryl) and Hydroxyzine. These tend to cause drowsiness. With second generation H1 antagonists cause fewer side effects and include drugs like loratadine (Claritin) and cetirizine (Zyrtec)
H2 antagonists primarily affect the gastrointestinal tract and include medications like famotidine (pepcid)
Typically when treating MCAS a person will be put on both a second generation H1 antagonist and an H2 antagonist.
When antihistamines do not treat symptoms well enough the next step is a mast cell mediator. The most common mast cell mediator is cromolyn sodium which is available by prescription only. (this is technically available OTC but it is at 1/50th the dose used for MCAS) Mast cell mediators work by preventing the degranulation of mast cells in the first place.
When both antihistamines and mast cell mediators are insufficient someone with MCAS might be prescribed a biologic such as Xolair to treat their remaining symptoms.
Sources:
American Academy of Allergy, Asthma, and Immunology
Mast Cell Hope
Mast Cell Activation Syndrome: Proposed Diagnostic Criteria
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