#Chemotherapy

[ceevee5]

[thepastisalreadywritten]

By Allison Pearson

23 March 2024

OH, NO. No. A sense that something was not right, that our wonderful Princess was perhaps in more trouble than we’d been told, was confirmed at 6pm on Friday with an unprecedented TV address that dealt a blow to the nation’s solar plexus.

Some will simply have been stunned by the news, hardly able to comprehend it (what, cancer twice in the Royal family within two months? But she’s so young).

Others will have been in tears, as I was, watching our Princess of Wales, parchment-pale, clearly fragile yet valiantly composing herself to record a message in that crystal-clear voice, reassuring us that, although it had been “an incredibly tough couple of months for our entire family,” she would be OK, given enough time, space and privacy.

One friend who heard it on the car radio pulled over to the side of the road and sobbed. “I am just so upset,” she texted.

Another confessed she was relieved that the Waleses hadn’t separated – one of the wilder rumours that had been flying around since the Princess of Wales was pictured in that photoshopped, too-smiley Mother’s Day picture without her wedding rings.

“For the backbone of Britain, we need those two to be together and happily married,” said my friend. So true.

William ’n’ Kate, Kate ’n’ William, a couple for almost the whole of their adult lives, one unimaginable without the other.

Our monarchy is assured as long as there is them (the Waleses will celebrate their thirteenth wedding anniversary on 29th April, six days after little Louis turns six).

Suddenly, with this announcement, we are reminded that they are only human too, vulnerable at times, and Britain is badly shaken.

As she finished her statement, the ramifications started to sink in. Prince William has to deal with a father and a wife with cancer at the same time.

There are haunting echoes of Diana, too, another beloved princess whose personal challenges played out so publicly.

Poor William must feel like there are snipers in the garden taking aim at his family.

You could tell the children were uppermost in her mind, just as they are for any parent who is told they have cancer.

George, Charlotte and Louis, she spoke their names aloud, her darlings. You know, I think they were the real reason she steeled herself to do it.

To sit there on that wooden bench with spring bursting out behind her. Daffodils on a grassy bank, trees in blossom – a cruelly lovely backdrop for such sad tidings.

How simply dressed she was in a matelot jumper and jeans, stripped of finery and clothed, instead, in a becoming humility, her beauty thrown into sharp relief by the strain on her face.

A 42-year-old who is uniquely privileged yet now confronts every woman’s frightening brush with mortality.

Her statement was carefully timed to coincide with the start of the school Easter holidays so the children could be safe at home and wouldn’t have to endure whispers in class about Mummy’s illness.

(Sparing them the agonies of embarrassment young William and Harry suffered at boarding school when Charles and Diana were getting divorced.)

It’s not easy to protect your children when their grandfather is the King and their father his heir.

The Prince and Princess of Wales have always been concerned to make things as normal, as Middleton, as possible, for their young family; this is their toughest test yet.

Was there more than a hint of rebuke in the Princess’s carefully measured words for a media that really has shown neither patience nor “understanding” since she disappeared from public view to have abdominal surgery?

She could be forgiven for being furious. (Believe me, many of us are furious on her behalf.)

“William and I have been doing everything we can to process and manage this privately for the sake of our young family,” she said pointedly.

“As you can imagine, this has taken time. It has taken me time to recover from major surgery in order to start my treatment.

But, most importantly, it has taken us time to explain everything to George, Charlotte and Louis in a way that is appropriate for them, and to reassure them that I am going to be OK.”

“Back off,” she was saying in the politest possible way, “leave me and my kids alone.”

Of course, she needed time to come to terms with the shattering blow of having a life-threatening illness and three children under 10. Every mother’s nightmare.

But time is one thing the vultures and conspiracy theorists were not prepared to give her.

In the vacuum Kensington Palace foolishly allowed to develop, the vilest rumours flourished.

Had she undergone cosmetic surgery? Wasn’t she just slacking? Why wasn’t William taking up more duties to relieve his sick father?

Had Catherine left William? Was it a lookalike pictured with William at a Windsor farm shop?

The gossip went global, causing universal hysteria.

Imagine feeling as sick and scared as the Princess must have done, yet being under pressure to show yourself in order to disprove the lies and appease the baying online mob. It’s barbaric.

I hope those who made such disgusting comments are burning with shame today now that we know the reason she hid away.

It wasn’t only ghouls with a conscience bypass who were trying to fill the gaps in the story.

Theories also came from people who adore the Royal family and were deeply worried for the absent Princess. We love and respect her so much.

Incredibly, in a poll earlier this month, the recuperating Princess still managed to emerge as the most popular royal, narrowly ahead of her husband.

Despite the slurry of accusations – not least the appalling claim in an early draft of a book by Omid Scobie (media snitch), that she was one of the two alleged “royal racists” who speculated on the baby’s likely skin colour – their figures are broadly unchanged since a previous poll in 2023.

Never Put a Foot Wrong is said so often it’s practically the definition of her.

Turns out there may be stresses and strains to appearing always in control, to aiming for perfection, that can eat away at a sensitive person not born to be royal.

Catherine says her job brings her joy; it must also have caused worry (such remorseless spotlight scrutiny).

We should reflect on that, I think. On what it’s reasonable to expect from one human being who expects so much of herself.

How the Princess came to win such a large place in British people’s hearts is better than any fairy tale.

Bullied at school, the quiet, sporty brunette was famous for her record-breaking high jump and tenacious character.

She had blossomed by the time she met William in their first term at St Andrew’s.

At 29, when they finally exchanged vows in Westminster Abbey, she was the first royal bride to have a university degree; the first to have lived with her husband before marriage; the first to be raised in a house that had a street number instead of a fancy name and a moat with swans.

As second in line to the throne, William was expected to pick his princess from a select group of well-bred young fillies.

Hot favourites included Davina Duckworth-Chad and one Isabella Amaryllis Charlotte Anstruther-Gough-Calthorpe.

Enough hyphens to make plain Catherine Middleton of Bucklebury, Berkshire, feel a little inadequate, you might think.

Except that, when a friend at university told Catherine how lucky she was to be going out with Prince William, a smiling Catherine replied: “He’s lucky to have me.”

The years have proved her right, haven’t they?

The death of Diana left William a damaged, stubborn and angry young man, acutely aware he was a prisoner of fate and railing at the media who pursued his mother.

Catherine has calmed him, rebuilding trust while providing the regular family life he had never known.

She has grown brilliantly into the role and the Waleses are a formidable team, lighting up any event they enter.

Now, it is his turn to soothe and calm her, although he must be deeply worried.

“Having William by my side is a great source of comfort and reassurance too, as is the love, support and kindness that has been shown by so many of you. It means so much to us both,” she said.

The King was right to salute his daughter-in-law for her courage. Imagine what it takes to first tell your small children you have cancer and then tell the whole world.

She did it so naturally, so sweetly, with such great empathy for others with that cruel disease that no one could possibly guess what it cost her. But it cost her.

She has told George, Charlotte and Louis that Mummy is well, and getting better, but the only way she will make a full recovery is if she’s left alone as she completes her treatment.

Will the vultures listen? Will they give her the time she needs or go back pecking for more?

Millions of us are praying for the return to health of our wonderful Princess of Wales. She has all our support and love.

A Britain without her is unthinkable, unbearable. Take your time, Princess, take your time.

💙🌹💙

[destielmemenews]

“In January, I underwent major abdominal surgery in London and at the time, it was thought that my condition was non-cancerous,” she said in a video announcement.

“The surgery was successful. However, tests after the operation found cancer had been present. My medical team therefore advised that I should undergo a course of preventative chemotherapy and I am now in the early stages of that treatment.”

source 1

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[mindblowingscience]

Cancer drug resistance remains a leading reason why treatments for specific cancers eventually do not work. A team of Stony Brook University researchers led by Gábor Balázsi have been testing drug resistance with mammalian cell lines. Their latest investigation reveals that taking a part of a DNA amplification from a cell, which causes resistance, and placing it back in, actually stops the drug resistance. This finding, published in PNAS, could lead to additional treatment methods in the attempt to stop chemotherapy drug resistance.

Continue Reading.

[sarahsyna]

My aunt is currently undergoing chemo, and since I can't visit her (because it'd involve being on a train a lot, which is an exposure risk I am unwilling to take) I want to make her a little care package.

Could anyone let me know what would be good gifts that'd help her out while she's dealing with this?

[eretzyisrael]

Good News From Israel

Israel's Good News Newsletter to 14th Apr 24

Read More: Good News From Israel

In the 14th Apr 24 edition of Israel’s good news, the highlights include:

A music graduate from Oxford Uni is now an agronomist rebuilding Israeli farms.

A revolutionary Israeli alternative to antibiotics has begun human trials.

Jews hand out dates to Muslim worshippers at the end of Ramadan fasting.

Israelis fly out to help victims of Taiwan’s earthquake.

An invitation to see some “cool” Israeli climate technology.

Commercial organizations can help make Aliyah much easier.

Israeli sporting stars are truly flying the flag.

Two current Jewish Presidents helped write a Torah scroll for Peace.

As you probably know, Israel and its allies have just defended the Jewish State from hundreds of drones and missiles launched by Iran.  The good news is that there were no Israeli fatalities and almost all of the projectiles were intercepted.  This newsletter was compiled before the news of that attack. 

[valentinetheworm]

Tyler Durden x Bright Mac fan art

[acti-veg]

is chemotherapy vegan?

Almost all modern medical techniques and processes have been tested on animals, but obviously a vegan patient cannot be expected to refuse chemotherapy on this basis.

This would clearly fall into the category of doing what is possible and practicable to avoid animal exploitation, and avoiding treatment or medication would certainly not be a reasonable expectation to place on anyone, vegan or not.

[heythereimb]

Cancer Update/ Finding the Good in Today pt 13

[ Cross posted from Reddit ]

If you don’t know me, hey there I'm B and I have sarcoma.

In December of last year Technodad gave me the challenge of finding one good thing in every day, no matter how small. Since then I've been sharing my list of good things from the last month.

I've been struggling to have good months. It’s hard. I am trying. That's what's important.

October's Good Things:

- the image "Creation of Fresco" by Reddit user u/Lirimi06

- a secret I'm not allowed to share

- finished a chemo round

- chemo is helping

I am very sick. I didn't prewrite at all this month. I am sorry if none of this makes sense. It's 9pm and I'm kinda dizzy even laying down. Send anti-stomach bug vibes my way please. In the words of Reddit user u/StrawberryGS I am "just strong enough to be miserable."

I did it. I did the list.

Until next time.

[thepastisalreadywritten]

The most powerful moment of the coronation of King Charles III was not the gold glittering off carriages or epaulettes — not the pomp and show and signifiers of power.

It was precisely their opposite: when Charles shed his gold robes and stood in a thin white shirt, his frail humanity implied.

Then a screen was erected around him and, shielded, he had a private consultation with the Archbishop of Canterbury, who dabbed anointing oil with his hands on Charles’s bare breast.

"This was the most solemn and personal of moments,” Buckingham Palace said.

Charles was bare before God, in privacy, God being one of the last beings with no need to sign a non-disclosure agreement.

The Princess of Wales looked on as the screen shielded her father-in-law.

By contrast, she was at that point the most magnificent she had ever been, swathed in layer upon layer of regality, the dress, the robes, the hanging chains, headpiece and ribbons all serving to move the viewing gaze — subjects in every sense — from our awareness of Catherine Middleton with her everyday human DNA and towards the shared fiction of her transcendent queenliness.

Less than a year later, this moment is remembered with new and terrible power.

It is spring again, but it’s a time of hard Lenten moral reflection for us as a nation, in relationship to our royals, as well as an ever more voraciously unprivate modern celebrity culture.

Both the King and the princess have cancer, the latter’s disclosed by Catherine in an unprecedented video address on Friday, March 22.

Catherine’s speech was something of a plea bargain in which she traded not only her customary silence but her most personal of health ordeals in order to put an end to toxic rumours swirling online that had become in tone like an unruly mob rattling at the palace gates.

Or rattling at the figurative locks on her medical notes, with three workers at the London Clinic, where she and the King were treated, suspended and under investigation for allegedly trying to access her records (hers, it is important to note, the King’s were unmolested).

📷: Getty Images

What was so powerful about the anointing of the King was the sacredness of that space in which he could be fully human away from observation and judgment.

There should be another one-on-one consultation that is sacred, where anyone, from King to princess to pauper, can expect to be shriven in total privacy, and that is the sanctity of the medical room.

It used to be that priests were our only bound confidants, we could trust them to be privy to all our spiritual ills.

Now doctors are our secular priests: bound by law and ethics to enshrine confidentiality at the heart of the patient relationship.

As a result, our medical privacy in an age of oversharing and online surveillance feels both stranger and more necessary.

If we knew our every GP-inspected rash was to be posted on TikTok for the nation, many of us would quite literally die of embarrassment.

The King’s appointment behind the three-sided screen can now be viewed through the lens of royal illness.

The lavishly embroidered panels and expensive white shirt now replaced by the flimsy three-sided ward screen on wheels and thin hospital gown that can humble us all.

But it also enacts a principle at the very heart of becoming the monarch.

The medical-like screen is erected in the coronation to tell us there are some places the public cannot go; to tell us that there are sacredly personal moments in which a person, any person, however swathed in our projections of power, needs to be nakedly human.

Otherwise, they will go mad. We need to make sure the screens are erected around Catherine now.

Much is said, quite a lot of it by Prince Harry himself, of the dangers of the wives of the princes repeating the tragic history of their mother, Princess Diana, hunted by photographers.

He remains phobic to any hint of tabloid persecution or paparazzi chase. But this is a sideshow, even an anachronism in 2024.

He and others have not recognised how the “chase” has changed. Who needs paparazzi when there are a billion citizen hacks ready to take pictures with their phones, in case a convalescing woman nips to a Windsor farm shop with her husband?

Instead, the appetite now is not to see but to know.

The royals used to have a contract with the public: we pay for them, and in return, they give us their presence.

Nearly all of their official job is to do with surface: to show up, to put in appearances at a set number of functions, whether at the opening of parliament or the opening of a leisure centre.

But now parts of the online mob seem to be staging a coup. We want more than the surface, we want to puncture the skin barrier of the royal family and occupy from the inside.

The “fans” have become an invasive virus. The royal analogy is often that they are trapped in a gilded zoo. This new model, instead, casts the royals more as lab rats.

When Catherine disappeared from view in January after announcing a “planned abdominal operation,” the response from internet truthers was one of irate entitlement.

They are now the 1980s tabloids: ravening for intimacies and making stuff up when thwarted.

This wasn’t the boomer generation, who are both more respectful of the royals and more private about their own health.

It was the fortysomething mothers frustrated when they can’t track the phone location of everyone in their life; or the twentysomethings on Snap Map.

Both desperate for their personalised new Netflix season of “The Royals” to drop.

Catherine presents with such stoicism and dignity, it is easy to forget where this new invasiveness started: when she was pregnant with Prince George in December 2012 and hospitalised for extreme morning sickness.

While she was sleeping on the ward, a radio station in Australia rang the hospital switchboard pretending to be the Queen.

They broadcast the nurse’s comments about Catherine’s “retching.”

One could only find this prank funny if Catherine had already — a young, wretchedly ill, pregnant woman — been dehumanised.

George is now ten and his mother hospitalised again, and in that decade, the physical security of ill royals may have tightened but their claim to bodily autonomy seems to have weakened.

Some say Kensington Palace “brought it on themselves” by their wish for discretion; this claim is duplicitous.

The late Queen Elizabeth II became increasingly debilitated in her final years with not much detail ever given; just as her father, King George VI, died without disclosing his lung cancer.

I’m glad that the British do not subject their heads of state to the same publicised medical reports as the president of the United States; one shouldn’t have to present a stool swab to sit on the throne.

No, instead the apparent justification of all those clicking and posting conspiracy theories “worried for Catherine’s welfare” was this sinful truth.

As a beautiful, 42-year-old mother of three, her drama was more box office than the ailments of those older, a pound of her flesh was worth more.

Pity, Susan Sontag said in her 1978 book Illness as Metaphor, is close to contempt.

Back then cancer was still taboo. Those around the patient, Sontag says, “express pity but also convey contempt.”

Ask any cancer patient and they will say they don’t want pity: it is too isolating, it sets them apart, an unwanted privilege.

This is why the video plea of Catherine was one of affinity, rather than pity or privilege.

Last year, she sat in robes in Westminster Abbey at the coronation of her father-in-law, next to her future king son and future king husband.

In her video address last week, she sat on a classically English garden bench, pale, alone and in jeans, as bare of pomp as any royal can be.

No mention of kings or titles, just Diana’s ring on her hand.

Rather she gave an appeal, parent to parent, human to human, about her “huge shock” and her care for her “young family.”

And, finally, her kinship with anyone who lives in a vulnerable human body susceptible to a democratic illness like cancer, “you are not alone.”

Or, to paraphrase Richard Curtis:

“I’m just a girl, standing in front of a public, asking for some time to endure gruelling chemotherapy."

NOTE: Additional photos have been included in this article.

[womeninfictionandirl]

Dr. Jane Cooke Wright by The Covatar

Jane Cooke Wright (also known as "Jane Jones") (November 20, 1919 – February 19, 2013) was a pioneering cancer researcher and surgeon noted for her contributions to chemotherapy. In particular, Wright is credited with developing the technique of using human tissue culture rather than laboratory mice to test the effects of potential drugs on cancer cells. She also pioneered the use of the drug methotrexate to treat breast cancer and skin cancer.

[speedyz3]

Round two of Chemo Therapy is today. I can only hope that the side effects are as minimal as the last one. I’ve got my bag packed with snacks and some magazines for a long day at the hospital.

[mindblowingscience]

The silica nanoparticle can be loaded with temozolomide, a small molecule drug used to treat glioblastoma brain tumors, the researchers say.

“This chemotherapy drug has limitations—it t doesn’t stay in the blood for very long, it can be pushed out of the brain, and it doesn’t have high penetration from blood into the brain,” says Taskeen Janjua, from the School of Pharmacy at the University of Queensland.

“To make the drug more effective, we developed an ultra-small, large pore nanoparticle to help it move through the blood-brain barrier and penetrate the tumor while also reducing unwanted patient side effects.

“This strategy could be a more effective way to treat brain cancer and prevent it from coming back,” Janjua says.

Continue Reading

[the-kitty-hell-system]

kinda hating how cancer and chemotherapy and shit is such a hush topic like. yes i dont have hair because of chemotherapy that i am on because i have liver cancer. why are you telling me to not talk abt the CONDITION that affects me more than it does you. like ur not the one who COULD die from this and needs a transplant?

[rosegold86]

@g33k3d