#SCIENCE NEWS

[orchidbutch]

Hi everyone, I wanted to share some promising developments about a nasal COVID-19 vaccine:

"THIS IS HUGE! Researchers have developed a nasal COVID-19 vaccine that BLOCKS transmission of the virus. This suggests vaccines delivered directly to the nose or mouth could play a CRITICAL role in containing the spread of respiratory infections. Phase I clinical trials HAVE BEEN APPROVED!"

Link to said study:

Link to thread on Bluesky: /profile/sailorrooscout.bsky.social/post/3kyoj6hgihr2v

[viola-sororia]

first class news paleontologists never disappoint

[nwmo]

LITTLE GUY SPOTTED

[reasonsforhope]

"In Australia, a man was kept alive for 100 days on an artificial heart made of titanium while a donor heart was eventually found.

This is the longest-ever period that a man has been kept alive by an artificial heart, giving its developers encouragement that it can play a major role in supporting waiting list patients whose hearts are failing.

5 months ago, a man in his forties received the BiVACOR Total Artificial Heart (TAH) after experiencing heart failure. The TAH has no pumps, valves, or other moving parts susceptible to wear. Instead, magnetic levitation permits a single rotor to pump blood to the body through both ventricles.

He was able to leave the hospital even, before a donor heart was found that was transplanted successfully.

In a statement, BiVACOR, St. Vincent’s Hospital where the surgery was carried out, and Monash University which provided the grant funding for the development of the TAH, said that the result is a sign the artificial heart could potentially offer a long-term option for people suffering from heart failure.

BiVACOR’s founder, Australian bioengineer Daniel Timms, who invented the device, said it was “exhilarating to see decades of work come to fruition.”

“The entire BiVACOR team is deeply grateful to the patient and his family for placing their trust in our Total Artificial Heart,” he said in the statement. “Their bravery will pave the way for countless more patients to receive this lifesaving technology.”

In the United States, there are around 3,500 donor hearts made available every year for more than 4,400 people who join the waiting list.

The TAH has already been tested in an early feasibility study in search of eventual FDA approval. 5 patients received the device, CNN reports, with the first being last July, when a 58-year-old man suffering end-stage heart failure received the implant during surgery at Texas Medical Center.

The four others also received it successfully, and organizers hope to expand it to 15 patients."

-via Good News Network, March 18, 2025

[feelingautistic]

Exciting news for the cute shark lovers of the world! We finally have a recorded sighting of a baby great white shark, likely only a few hours old.

The question of where great white sharks give birth still remains a mystery to this day but this footage may suggest the coasts of California, where the footage was taken, are a site where these sharks give birth.

[amnhnyc]

One small step for leeches, one giant leap for leechkind! For the first time, we have concrete evidence that at least one species of terrestrial leech in Madagascar can jump. Mai’s work is important to conservation efforts because leeches are increasingly being collected to survey vertebrate biodiversity. By analyzing their blood meals, researchers are able to identify other animals living alongside the leeches, ranging from wildcats to frogs to ground-dwelling birds. Read more about Mai's research in our latest blog post.

Have you ever seen a leech jump? Let us know in the comments!

[traverse-our-universe]

Stunning New Images of Jupiter From NASA’s Juno Spacecraft (read article here)

[arminreindl]

Deinosuchus: Giant Alligator or something older?

I know the title sucks, I couldn't think of anything poetic or clever ok? Anyways, still catching up on croc papers to summarize and this one did make a few waves when it was published about a week ago.

"Expanded phylogeny elucidates Deinosuchus relationships, crocodylian osmoregulation and body-size evolution" is a new paper by Walter, Massonne, Paiva, Martin, Delfino and Rabi, with quite a few of these authors having considerable experience with crocodile research. The thesis of the study is both simple and unusual. They suggest that several crocodilians traditionally held as stem-alligators, namely Deinosuchus, Leidyosuchus and Diplocynodon, weren't alligatoroids at all. In fact, if the study holds up they might not have been true crocodilians.

Ok, lets take a step back and briefly look at our main three subjects. Deinosuchus of course needs no introduction, a titan of the Cretaceous also known as the terror crocodile in some more casual sources, its easily one of the most iconic fossil crocodiles. It lived on either side of the Western Interior Seaway during the Campanian, fed on giant turtles and dinosaurs and with size estimates of up to 12 meters its easily among the largest crocodylomorphs who have ever lived.

Artwork by Brian Engh

Leidyosuchus also lived during the Campanian in North America and I would argue is iconic in its own right, albeit in a different way. It's historic to say the least and once housed a whole plethora of species, but has recently fallen on hard times in the sense that most of said species have since then been transferred to the genus Borealosuchus.

Artwork by Joschua Knüppe

Finally there's Diplocynodon, the quintessential croc of Cenozoic Europe. With around a dozen species found from the Paleocene to the Miocene all across Europe, it might be one of the most well studied fossil crocs there is, even if its less well known by the public due to its relatively unimpressive size range.

Artwork by Paleocreations

All three of these have traditionally been regarded as early members of the Alligatoroidea, one of the three main branches that form Crocodilia. In these older studies, Alligatoroidea can be broken up into three groups nested within one another. Obviously the crown is formed by the two living subfamilies, Alligatorinae and Caimaninae, both of which fall into the family Alligatoridae. If you take a step further out you get to the clade Globidonta, which in addition to proper Alligatorids also includes some basal forms with blunt cheek teeth as well as Orientalosuchina, tho jury's still out on whether or not they are truly alligator-relatives. And if you take a final step back and view Alligatoroidea as a whole, then you got our three main subjects neatly lined up outside of Globidonta in varying positions.

Below a highly simplified depiction of previous phylogenies. Deinosuchus, Leidyosuchus and Diplocynodon are often regarded as non-globidontan alligatoroids.

This new study however changes that long standing concensus. The team argues that several features we once thought defined alligatoroids are actually way more common across Crocodilia and even outside of it while also leverging some of the features of Deinosuchus and co. that have always been out of the ordinary. For instance, early alligatoroids are generally characterized as being comparably small, having had short, rounded heads, the afforementioned globular cheek teeth and of course the feature that still allows us to differentiate them from true crocodiles, the fact that they have a clear overbite. Now Leidyosuchus, Deinosuchus and Diplocynodon all have proportionally longer snouts than alligatoroids, their teeth interfinger like in crocodiles and most prominently (and namegiving for Diplocynodon) there is a large notch behind the snout tip that serves to receive two enlarged teeth of the lower jaw. These are of course just superficial examples, but if you wanna get into the nitty gritty check out the paper.

Below a simplified version of the papers phylogeny. Borealosuchus clades with Diplocynodon and Leidyosuchus and Deinosuchus are successive taxa. Planocraniidae are the sister to Crocodilia, which consists of Crocodyloids, Gavialoids (together Longirostres) and Alligatoroids.

Something also worth addressing in light of these results is salt tolerance in crocodilians and paleogeography. Basically, if you ignore Deinosuchus and co. (or well, just follow this new paper), then it is most likely that alligatoroids originated on the continent of Laramidia, i.e. the western half of America back when it was bisected by an enormous inland sea. Today, alligatoroids are famously intolerant of saltwater, yes, there are instances where alligators have been known to enter coastal waters, but its a far cry from what true crocodiles can achieve (just an example here's my recent post on Caribbean crocodiles). Given that alligatoroids don't appear on Appalachia, the other half of North America, until after the inland sea closes, this very much suggest that this intolerance goes way back. This has however always been at odds with Deinosuchus, which famously showed up along both the eastern and the western coast of the inland sea and at least lived close enough to the coast to leave its mark on the shells of sea turtles. We know it inhabited various near-shore environments and even stable isotope analysis of its teeth points towards it consuming either saltwater or prey that lives in the ocean. To a lesser degree its worth mentioning Diplocynodon, which though usually a freshwater animal has at least one species from coastal deposits. Now I do think its worth highlighting that just being salt tolerant doesn't necessarily mean they can't have been alligatoroids, given that salt glands could have easily been lost after Deinosuchus split off from other alligatoroids. Nevertheless, a position as a stem-crocodilian does add up with it being salt tolerant, with the assumption being that being tolerant to saltwater is basal to crocodilians as a whole and was simply lost in a select few lineages such as alligatoroids.

Given that its range spanned both coastlines of the Western Interior Seaway as well as direct evidence for interactions with marine life, Deinosuchus likely ventured out into the sea from time to time like some modern crocodiles.

There's also the matter of timing. When alligatoroids first appeared 82 million years ago, we already see the classic blunt-snouted morphotype with Brachychampsa and our dear giant Deinosuchus. Now if both were alligatoroids, this would suggest that they've been separate quite some time before that to bring forth these drastically different forms, yet attempts to estimate the divergence date suggest that they split no earlier than 90 million years ago. So if Deinosuchus is not an alligatoroid, then the timeline adds up a bit better. However I think the best example of this new topology really explaining an evolutionary mystery doesn't come from Deinosuchus, but from Diplocynodon. Those that know me might remember that I started working on researching Diplocynodon for Wikipedia, a process that's been slow and painfull both due to the 200 years of research history and the good dozen or so species placed in this genus. Tangent aside, one big mystery around Diplocynodon is its origin. They first appear in the Paleocene and survive till the Miocene, tend to stick to freshwater and oh yeah, species of this genus are endemic to Europe. Given that previous studies recovered them as alligatoroids, nobody was quite sure where Diplocynodon came from. Did they originate in North America and cross the Atlantic? Where they salt tolerant before and simply stuck to freshwater once in Europe? Or are they a much older alligatoroid lineage that entered Europe via Asia after having crossed Beringia. You know, the kind of headbreaking stuff we get when the fossil record is incomplete. But this new study recovers Diplocynodon as being closely related to the non-crocodilian Borealosuchus from the Cretaceous to Paleogene of North America. And that makes some sense, historically the two have been noted to be similar, hell there were even cases when Borealosuchus remains were thought to be North American examples of Diplocynodon. And Borealosuchus has the same double caniniforms as the other crocs we discussed so far. So when our three former alligatoroids got pushed outside of Crocodilia, Diplocynodon ended up forming a clade with Borealosuchus. And since Borealosuchus was wide spread in America by the late Cretaceous, and possibly salt tolerant, then it could have easily spread across Greenland and Scandinavia after the impact, giving rise to Diplocynodon.

The results of this study seem to suggest that Borealosuchus and Diplocynodon are more closely related that previously thought.

And since this is a Deinosuchus paper...of course theres discussion about its size. A point raised by the authors is that previous estimates typically employ the length of the skull or lower jaw to estimate body length, which might not be ideal and is something I definitely agree with. The problem is that skull length can vary DRASTICALLY. Some animals like early alligatoroids have very short skulls, but then you have animals in gharials in which the snout is highly elongated in connection to their ecology. Given that Deinosuchus has a relatively long snout compared to early alligatoroids, size estimates based on this might very well overestimate its length, while the team argues that head width would yield a more reasonable results. Previous size estimates have ranged from as low as 8 meters to as large as 12, which generally made it the largest croc to have ever existed. Now in addition to using head width, the team furthermote made use of whats known as the phylgenetic approach, which essentially bypasses the problem of a single modern analogue with peculariar proportions influencing the result. Now there is a bunch more that went into the conclusion, but ultimately the authors conclude that in their opinion, the most likely length for the studied Deinosuchus riograndensis specimen was a mere 7.66 meters in total length. And before you jump to any conclusions, DEINOSUCHUS WOULD HAVE GOTTEN BIGGER TRUST ME. I know having read "12 meter upper estimate" earlier is quite a contrast with the resulting 7.66 meters, but keep in mind this latter estimate is just one specimen. A specimen that in previous studies was estimated to have grown to a length of somewhere between 8.4 - 9.8 meters. Now yes, this is still a downsize overall, but also given that this specimen is far from the largest Deinosuchus we have, this means that other individuals would have certainly grown larger. Maybe not those mythical 12 meters, but still very large. So please keep that in mind.

Two different interpretations of the same specimen of Deinosuchus. Top a proportionally larger-headed reconstruction by randomdinos, bottom a smaller-headed reconstruction by Fadeno. I do not care to weigh in on the debate other than to say that size tends to fluctuate a lot between studies and that I'm sure this won't be the last up or downsize we see.

Regardless of the details, this would put Deinosuchus in the "giant" size category of 7+ meters, while early alligatoroids generally fall into the small (<1.5 meters) or medium (1.5-4 meters) size categories. The authors make an interesting observation relating to gigantism in crocs at this point in the paper. Prevously, temperature and lifestyle were considered important factors in crocs obtaining such large sizes, but the team adds to that the overall nature of the available ecosystem. In the case of Deinosuchus, it inhabited enormous coastal wetlands under favorable temperature conditions and with abundant large sized prey, a perfect combination for an animal to grow to an enormous size. And this appears to be a repeated pattern that is so common its pretty much regarded as a constant. To quote the authors, "a world with enormous crocodyliforms may have been rather the norm than the exception in the last ~ 130 million years." For other examples look no further than the Miocene of South America, the extensive wetlands of Cretaceous North Africa or even Pleistocene Kenya.

One striking example for repeated gigantism in crocodilians can be found in Miocene South America, when the caimans Purussaurus and Mourasuchus both independently reached large sizes alongside the gharial Gryposcuhus. The illustration below by Joschua Knüppe features some of the smaller earlier members of these species in the Pebas Megawetlands.

So that's it then, case closed. Deinosuchus and co aren't salt-tolerant alligators, they are stem-crocodilians. Deinosuchus was smaller than previously thought and Diplocynodon diverged from Borealosuchus. Leidyosuchus is also there. It all adds up, right? Well not quite. This all is a massive upheaval from what has previously been accepted and while there were outliers before, the alligatoroid affinities of these animals were the concensus for a long time. Future studies will need to repeat the process, analyse the data and the anatomical features and replicate the results before we can be sure that this isn't just a surprisingly logical outlier. Already I heard some doubts from croc researchers, so time will tell if Deinosuchus truly was some ancient crocodilian-cousin or if previous researchers were correct in considering it a stem-alligator. I for one will keep my eyes peeled.

[factsbyscience]

A United Nations-backed scientific assessment released in early 2023 confirmed that the ozone layer is on track to recover to 1980 levels:

• Antarctic ozone hole: expected to heal by around 2066

• Arctic ozone: projected to recover by 2045

• Global ozone: could return to 1980 levels by 2040

These projections are based on compliance with the Montreal Protocol (1987), which phased out ozone-depleting substances like CFCs.

MIT scientists, among many others worldwide, have contributed to the understanding and monitoring of the ozone layer, often publishing peer-reviewed work and collaborating with international assessments.

The Antarctic ozone hole is healing, largely due to international environmental policy. Full recovery is projected by 2066, assuming continued global cooperation.

Follow us 👉 @factsbyscience for more science and daily facts.🤓 

Enjoy the rest of your day.😇

[dykehelly]

NIH slashes overhead payments for research, sparking outrage

In a Friday night move that quickly drew howls of protest from the U.S. biomedical research community, President Donald Trump’s administration today announced it is immediately reducing by at least half the so-called indirect cost payments that the National Institutes of Health (NIH) makes to universities, hospitals, and research institutes to help cover facilities and administrative costs.

A 15% indirect cost rate will now apply to all new and existing grants, NIH said in a memo from its Director’s office. Typically, about 30% of an average NIH grant to an institution is earmarked for indirect costs, according to NIH, but some universities get much higher rates. In 2023, NIH, the world’s largest funder of biomedical research, spent nearly $9 billion on indirect costs; the change would likely leave research institutions needing to find billions of dollars from other sources to support laboratories, students, and staff.

So this hasn't gotten much media play because it's so administrative and specific but it's like....really, really, really bad for the entire scientific research ecosystem in this country. I have friends who could lose their jobs, I could lose my job. It's possible that the pushback will halt this, but it now has academia in a REALLY bad position in which we could be forced to (for example) cut DEI programs in order to maintain appropriate funding levels.

[irl-loading-screens]

Yeah I'm pretty sure that's just POT OF GREED, WHICH ALLOWS ME TO DRAW TWO NEW CARDS FROM MY DECK

[my-autism-adhd-blog]

Apparently Trump wants to build a giant golden dome (military weapon not an actual dome) around America to deflect missiles and stuff. Here’s an excerpt from the article:

In the face of nuclear threats from adversaries like Russia, China and North Korea, some politicians are clamoring for a system to reliably protect the United States from incoming missiles. That’s the aim of President Donald Trump’s plan for a next-generation missile defense system, dubbed the “Golden Dome.” Trump announced on May 20 that an architecture had been selected and that the system would be operational before the end of his term, at a cost of $175 billion. But some scientists suggest that implementing such a system, as called for by a January executive order, would be daunting.

Here’s the full article if anyone wants to read it:

[reasonsforhope]

"If you're hoping that reef-restoring coral larvae will settle down in damaged reefs, you can't just sit around and wait for it to happen. You have to get out there and entice the larvae, which is exactly what a new algae-based gel is designed to do.

While we may think of coral reefs' "skeletons" as being composed solely of calcium carbonate produced by coral polyps, much of the material is in fact generated by what are known as crustose coralline algae.

Along with contributing greatly to the structural integrity of reefs, the algae-produced calcium carbonate also serves as a home to planktonic coral larvae. Once those formerly free-swimming organisms settle in and become polyps, they start producing reef-building calcium of their own.

It's a good arrangement for the coral, but it also benefits the algae.

Not only does the reef itself provide the algae with protection from the elements, the coral polyps also emit ammonia which the algae feed upon. It is therefore in the algae's best interest to entice any coral larvae that may be swimming past in the water column. In order to do so, the algae release metabolite chemicals that attract the larvae.

Led by Dr. Daniel Wangpraseurt, scientists at UC San Diego's Scripps Institution of Oceanography have now incorporated those metabolites into a gel that can be applied to degraded coral reefs. Called SNAP-X, the substance reportedly boosts coral larval settlement by up to 20 times as compared to untreated surfaces.

If the algae metabolites were just applied to the coral on their own, they would soon dissipate in the water, leaving the coral larvae unable to follow them to their source. For that reason, the researchers started by encasing the chemical molecules in durable silica nanoparticles. Those particles were then suspended within a biocompatible liquid blend of gelatin methacrylate and polyethylene glycol diacrylate.

When that liquid is sprayed or painted onto a surface – such as a piece of dead coral – then exposed to ultraviolet light, it polymerizes into a hydrogel form. That gel is capable of clinging to the surface for up to one month while immersed in flowing water, gradually releasing its larvae-attracting nanoparticles as it does so.

Initial lab tests showed that application of SNAP-X resulted in a six-fold increase in larval settlement. Subsequent tests that more accurately simulated the water flow on coral reefs, however, produced the 20-times figure.

It should be noted that all of the tests conducted so far have involved a single type of coral, but Wangpraseurt believes the technology should work on other species with a few tweaks.

"I think this material is a breakthrough that can hopefully make a big contribution to coral restoration," he says. "Biomedical scientists have spent a lot of time developing nanomaterials as drug carriers, and here we were able to apply some of that knowledge to marine restoration."

A paper on the research was recently published in the journal Trends in Biotechnology."

-via New Atlas, May 26, 2025

[victusinveritas]

[amnhnyc]

BIG NEWS: Apex is now on view at the Museum! Thought to be the largest and one of the most complete Stegosaurus specimens ever found, this 150-million-year-old fossil can now be seen in the Museum’s Griffin Exploration Atrium.

Apex will be studied as part of a new research initiative by scientists in the Museum’s Division of Paleontology focused on Stegosaurus biology, including the unique ornithischian dinosaur’s growth and life history. This work will require taking a small sample from a thigh bone of the specimen, which will become part of the Museum’s permanent scientific collection. All resulting 3D digital models, including the internal structures of its skull from new CT scans taken at the Museum, will be made available as a scientific resource for the wider community of researchers.

Photo: Alvaro Keding & Daniel Kim/ © AMNH