#pharmacy stuff

[i-am-thornqueen]

To whom this might concern,

When I suggest that you write down the dose of acetaminophen (brand name Tylenol; generic is also called paracetamol) and the time it was given, I am not questioning your ability to parent. Really, I'm not. I promise.

I'm making the suggestion to get a piece of paper or a little notebook to keep track of when and how much acetaminophen is being given to an infant/child/human of various stages of life because acetaminophen poisoning is one the most common forms of poisoning I see in the hospital. It's always an emergency. It's always horrifying. It's always (as far as I know) an accident - one parent loves their kid and sees that they are uncomfortable with a cold and wants to give pain/fever relief but doesn't tell the other parent. The other parent also loves their kid and sees they're uncomfortable and wants to give pain/fever relief without mentioning it. Both parents love their kid and are doing their best, but no one is keeping track of when or how much, and that's how accidents happen.

You have no idea how easy it is to accidentally overdose someone.

The dosing can be a lot of numbers to remember - 10 to 15 mg/kg per dose, every 4 to 6 hours, not to exceed 4000 mg in 24 hours. No more than 5 doses per 24 hours. Maximum in a child is 75 mg/kg/day not to exceed 4000 mg.

Can be exact dosing if using a liquid. Must round as best you can with tablets that have fixed dosing.

That's a lot to remember. Especially if your kid is sick and you're stressed about it.

Having a piece of paper to keep track of time and dose takes the stress out of keeping all that in your head. You will know the last time it was given. You know how much. You can count to make sure the amount is not above maximum.

If you need help with setting up the dose ranges, times, and maximums, ask any pharmacist. It's our job. Drugs are our specialty and dosing is our shtick.

And, if an accident does happen, the fact that you have all the times and amounts written down could make all the difference.

So, no, I am not questioning you as a parent. I am not saying that you're going to overdose your kid. All I am suggesting is a possible means of keeping track of everything in hopes that it can help prevent a worst case scenario. You don't even have to do it. Literally, all I am doing is suggesting it.

I just don't want to see another kid come into the ER with acetaminophen poisoning because their parents loved them too much.

[thatonegreyghost]

FARXIGA HAS A GENERIC NOW!

[amatesura]

Myrkkypulloja Turusta (vintage finnish poison bottles)

[gideonisms]

Once again frustrated by how Difficult it is to do very basic tasks

[kirby-the-gorb]

[autisticaradiamegido]

day 16

so instead of a drawing todays art is Babys First Embroidery

it will eventually be a patch for my Cool Patch Jacket once i get the border all filled in

it is in reference to the fact that i recently found out my state has a program that provides free naloxone to anybody who wants to carry it, no prescription necessary.

if you aren’t familiar, naloxone (brand name Narcan) is a medication that can be used to reverse an opioid overdose almost instantaneously in an emergency. in my state it is provided in the form of a nasal spray, but similar programs in other areas might offer auto-injectors, or other subcutaneous delivery methods.

BUT what i want to get across is that there are A LOT of these programs out there! if you’re curious, just google “free naloxone [your location]” and you might be able to get your hands on free or extremely reduced cost doses of naloxone to carry with you. most programs will train you how to administer the medication, and how to recognize signs of overdose.

harm reduction for drug users is important to me, regardless of who is using them, or for what purpose. and you can be part of that effort in your community SO easily by adding this to your first aid repertoire. it’s a bit like getting cpr certified! only literally so fast and cheap and easy like in my case i was in and out of the pharmacy in 15 minutes!!! you can literally save somebodys life with this, it is so so worth it.

[puppyeared]

i have an idea for a character design but what animals are usually associated with medicine??? the most common answer i got was snake, but i also thought of lab rats/mice, rabbits etc

[rannadylin]

Adventures in the American health care system: So my employer changed insurance companies this year, which is of course always a hassle. New Insurer sent a letter saying they do not cover Humalog, the bolus insulin I was on, but I could switch to Novolog or Fiasp. Fine, whatever, I had to switch from Novolog to Humalog when the previous insurer canceled their friendship with Novolog and I actually like Novolog better. So, saw my endocrinologist last Thursday and she put in the Novolog prescription. Comes Sunday, and the prescription is still "processing" at the pharmacy so I call and find out they are "waiting on approval." Turns out New Insurer is demanding a Prior Authorization.

For insulin.

For a type 1 diabetic patient.

For the specific brand of insulin THEY TOLD ME TO GET.

*smackhead*

Meanwhile, I am halfway through my last insulin pen and sending frantic messages and phone calls to the pharmacy and the doctor to get that PA processed so I can avoid rationing my insulin and, y'know, not die.

[fidgetspringer]

For a while now Røst has had some recurring issues with hotspots on his lower jaw and unfortunately they got worse while i was away this month. So right now we're doing a bunch of damage control to try and clear them up, which, for a dog that isn't a huge fan of handlig of any kind isn't very fun. And it doesn't help that i can't counter condition because the spots are in the drool zone and he turns sopping wet just at the suggestion of a treat. So all i can do it try to be patient and gentle when he gets anxious about handling, but i also do have to actually get things done, so basically i feel like the world's worst owner right now and Røst isn't exactly my biggest fan :(

[i-am-thornqueen]

I know drug names are sometimes ridiculous (sulfamethoxazole-trimethoprim anyone? or any drug with the suffix -mab) but I encountered the best misspelling of a drug today and I will never be able to look at this drug's name without thinking of this misspelling.

The drug is acamprosate and it is typically prescribed "acamprosate 666 mg PO TID" (orally three times a day).

On the order, it was written as 'acumprostate.'

A. Cum. Prostate.

When I tell you I had to contain myself. I was training a new pharmacist. My eye was twitching from the effort not to say anything other than 'oh dear, they misspelled the order, but that's okay, we know what they meant.' I wanted to call it a Freudian slip so bad! But I didn't it! I kept all the inappropriate comments inside! I earned my keep as a professional on this day!

But still.

A. Cum. Prostate.

A. Cum. Prostate.

A more perfect misspelled drug does not exist.

[lastoneout]

bro there's gotta be something wrong with me I should NOT be this tired two days after doing like three minor errands

[amatesura]

Apothecary bottles and jars from Rijksmuseum Boerhaave.

[fisheito]

moms at the sports game.....

[science-lover33]

Pharmacology Unveiled: How Medications Work on a Molecular Level"

Explore the science of pharmacology and delve into the mechanisms of action of commonly prescribed medications, shedding light on how they interact with the body's systems.

In the multifaceted domain of pharmacology, an intricate symphony of molecular interactions orchestrates the therapeutic effects of medications. A profound comprehension of the molecular underpinnings of pharmacological actions is indispensable for healthcare professionals, pharmaceutical scientists, and researchers. In this discourse, we embark on a comprehensive exploration of pharmacodynamics, elucidating the profound intricacies of how medications function at the molecular level.

Pharmacodynamics: A Multilayered Discipline

Pharmacodynamics constitutes the extensive scrutiny of the manner in which drugs interlace with specific molecular targets, often referred to as receptors or enzymes, within the human organism. Medications are meticulously designed to effectuate alterations in biochemical pathways, receptor kinetics, or enzymatic processes, aiming to modulate physiological phenomena to alleviate symptoms or remediate pathological states.

Receptor-Mediated Pharmacological Actions

A pivotal facet of pharmacodynamics lies in the receptor-mediated actions of medications. Receptors are intricate protein entities, frequently situated on the extracellular or intracellular domains of cells, that play a pivotal role in cellular communication and homeostasis. When a medication interfaces with a receptor, it initiates a cascade of molecular events, which, contingent upon the context, may potentiate or impede the cellular response.

Agonists and Antagonists: Puppets of Molecular Dance

In the intricate theater of pharmacodynamics, medications assume roles as either agonists or antagonists. Agonists aptly mimic the endogenous ligands or signaling molecules, seamlessly integrating into the receptor's binding pocket. This engagement sets forth a conformational alteration in the receptor, instigating cellular events replicating or augmenting the physiological response. Conversely, antagonists function as molecular antagonists, obstructing the receptor and forestalling the binding of endogenous signaling molecules. Consequently, the physiological response is negated or attenuated.

Enzymatic Interference: Orchestrating Biochemical Concertos

Certain medications orchestrate their therapeutic influence through the intricate domain of enzyme inhibition. Enzymes are the catalytic workhorses governing biochemical transformations in biological systems. Medications that selectively inhibit or modulate these enzymes effectively regulate the pace or character of these metabolic reactions, rendering them invaluable in conditions characterized by aberrant enzyme function.

Ion Channel Choreography: Modulating Electrophysiological Ballets

A notable mechanism of pharmacological action entails the modulation of ion channels. These proteinaceous conduits, reposing within cellular membranes, govern the flux of ions across these barriers. Medications designed to engage with ion channels effectively influence the electrochemical signaling within cells. The modulation of ion channels is instrumental in conditions such as arrhythmias, epilepsy, and neuropathic pain.

Pharmacogenetics: Personalizing Medication Regimens

The burgeoning realm of pharmacogenetics delves into the impact of an individual's genetic repertoire on their medication response. Genetic polymorphisms can significantly influence drug metabolism, receptor sensitivities, and pharmacological efficacy. Tailoring medication regimens to align with an individual's genetic makeup represents a burgeoning paradigm in personalized medicine.

Pharmacology unfolds as an intricate tapestry of molecular engagements and multifarious mechanisms. Medications, hewn with precision, are intended to engage with specific molecular entities, be it receptors, enzymes, or ion channels, aiming to modulate intricate biochemical processes to achieve therapeutic ends.

References

Rang, H. P., Dale, M. M., Ritter, J. M., & Flower, R. J. (2015). Rang & Dale's Pharmacology. Elsevier.

Katzung, B. G., & Trevor, A. J. (2021). Basic & Clinical Pharmacology. McGraw-Hill Education

Brunton, L. L., Knollmann, B. C., & Hilal-Dandan, R. (2020). Goodman & Gilman's: The Pharmacological Basis of Therapeutics. McGraw-Hill Education.

[fandomsandfeminism]

If I had known that getting an Adderall prescription would mean I would need to call the pharmacy every 2 days for the rest of my life, I might have rethought that choice.

Last time I filled my prescription, I could only get a partial fill because they didn't have the full 30 day supply. So I've just been calling every few days to be like "hey, can I fill the rest of this now?" and TODAY they are like "oh well…its too soon for you to refill this." What are you talking about? I'm trying to get the rest of the pills you were supposed to have given me 2 weeks ago. How can it be TOO SOON to get the pills you were supposed to give me 2 weeks ago? But you have it in stock TODAY. You might not have it in 6 days, when I run out, and again, these are pills included in the original prescription that I should have gotten two weeks ago anyway. How can it be too soon if they are 2 weeks late?

[lisbuns]