#cell traffic

[bpod-bpod]

Directing Traffic

Chemical messengers called chemokines are the traffic police of your body, telling cells on the move where to go via a chemokine concentration gradient. Atypical chemokine receptors (ACKRs) on certain cells help create these gradients by binding and engulfing specific chemokines. Three called GPR182, ACKR3 and ACKR4 are located in lymph and blood vessels, and research suggests may be found together in certain microenvironments within organs. However, there’s no comprehensive map of where they are. Researchers now genetically engineer mice with fluorescently-tagged GPR182, ACKR3, ACKR4 and ACKR-specific chemokines to locate them. Fluorescence microscopy revealed unique and shared distribution patterns of these ACKRs in a variety of organs, including the spleen (pictured, ACKR4 in green, GPR182 in red). Meanwhile, fluorescently-tagged chemokines revealed distinct activity zones for ACKR4 and GPR182 in the liver. These mouse models, therefore, provide a useful tool to probe ACKRs in different organs and microenvironments.

Written by Lux Fatimathas

Image from work by Serena Melgrati and colleagues

Institute for Research in Biomedicine, Università della Svizzera italiana, Bellinzona, Switzerland

Image originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)

Published in PLOS Biology, May 2023

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[californiatrafficschools]

The course is a review of driving laws and common sense. You can open the entire course and search it while taking the simple final test. Only 70% needed to pass. Save thousands on your auto insurance. Once you get into the course and are doing it, you will understand it wasn’t so bad after all! No need for further procrastination.

[tomdutch]

BICEP ???/&)?’!)?)?./$9???

[thatskindarough]

Hell yeahhhh got the power back much earlier than expected though the trees still on the line so it’s probably gonna have to be turned off for us while they try to get it off

[b1ackpaws]

yippe traffic light trio!

I am very normal about traffic light trio I absolutely do not have a album with over 120 photos of them-

not too proud of how the colors came out but I still like how it turned out :]

[olivetogo]

everyone give it up for the bad boys of the season

[johbeil]

A burnt-out case

“When you’re in the car with him, he rants incessantly that the roads are populated by morons, brain-amputated assholes, sons of bitches and worse who sit in their tin boxes in a half-dazed state, mainly staring at their goddamn phones with their heads down and behaving accordingly by stopping at green lights, constantly veering out of their lane and endangering others – absolutely unpredictable.…

[dogtoling]

i have so SOOOOO many things to draw but guess what guys. i dont know what to draw

[skydoesthings]

i do not understand how bingos work so I’m just gonna assume that it means what you think is gonna happen or what you want to happen

[quirinah]

road trip sketches from like two weeks ago

[thebreakfastgenie]

I had a stroke of inspiration at the Melissa Etheridge concert and saved the URL lesbianlesbianbean and I have never been more tempted to change my URL.

[dweemeister]

December 11, 2023

By Emily Badger, Ben Blatt, and Josh Katz

(The New York Times) — Sometime around 2009, American roads started to become deadlier for pedestrians, particularly at night. Fatalities have risen ever since, reversing the effects of decades of safety improvements. And it’s not clear why.

What’s even more perplexing: Nothing resembling this pattern has occurred in other comparably wealthy countries. In places like Canada and Australia, a much lower share of pedestrian fatalities occurs at night, and those fatalities — rarer in number — have generally been declining, not rising.

In America, these trends present a puzzle that has stumped experts on vehicle design, driver behavior, road safety and how they interact: What changed, starting about 15 years ago, that would cause rising numbers of pedestrian deaths specifically in the U.S. — and overwhelmingly at night?

“This is something that, quite frankly, our profession missed,” Rebecca Sanders, the founder of Safe Streets Research and Consulting, said of the toll of nighttime deaths. “I think we missed that for a long time.”

In 2021, more than 7,300 pedestrians died in America — three in four of them during the hours between sunset and sunrise.

This trend exists on top of what is already a growing gap in roadway deaths between the U.S. and other countries. Speed limits on local roads are often higher in the U.S., laws and cultural prohibitions against dangerous driving can be weaker, and American infrastructure in many ways has been designed to enable speeding cars.

Those baseline conditions may mean, researchers suggest, that American roads — and the pedestrians walking along them — have been especially susceptible to potential new risks like smartphones and bigger vehicles.

But even that is only part of the picture.

“I don’t have any definitive answers for this,” said Jessica Cicchino, the vice president for research at the Insurance Institute for Highway Safety. Ms. Cicchino, like many observers, has puzzled over how rapidly nighttime deaths have risen. “What is it that’s happening specifically in the dark?”

Some of the top-rated comments in the article's comment section blame the intense brightness of modern car lights (which this article fails to mention). But, obviously, there are probably multiple factors at play here which might have differing levels of causation depending on the locality or state you are talking about. And surely some of the factors listed in this article - namely distracted driving through cell phones - are anything but exclusive to the U.S.

That said, always drive safely and without distraction when you are taking to the roads.

[pad-wubbo]

"Neo-Pigeon", "Crystowl", "Circus Robin", "Waters of Roath", "Starry Reflection", "Cell Wall", "Esoteric Duck", "Mysterious Cone of the Lake", "Visible Mint Flavour" and "Spooky Tanuki".

Procreate (all of them).

1. Based on a Roath Park photo. The birds get really close when you have seeds in your hand.

2. Suggestion of my former charity shop coworker.

3. Christmas 2022 art. The hat is inspired by Maximillion Galactica from Ace Attorney.

4. Edited directly from another Roath Park photo.

5. Another Bob Ross-ish one, made with a simple zigzag of black then a dark overlay for the "water".

6. Inspired by some old biology textbook.

7. I don't know what kind of duck this is supposed to be, but it's a cosy one, for sure.

8. Somebody threw a traffic cone into Roath Park Lake. I have no clue as to why.

9. I wanted to paint something that looked visibly cold, and visibly sweet.

10. Halloween 2022 art. The hands are based on "treeman syndrome". Don't look it up.

I publish my paintings with a Creative Commons Attribution-ShareAlike 4.0 International licence.

[kyuuhakuninefold]

WIP: Air Traffic Control/Comms tower/lighthouse hybrid

This is maybe 30% done but i like how its going so far

[lightasthesun]

Comprehensive Lexicon Guide for First-Time SW Fic Readers:

Flimsi/Flimsiplast = Paper

Flimsiwork/Datawork = Paperwork

Stylus = Pen

Datapad = Tablet

Comlink/Comm = Communication Device/Phone

Binders = Handcuffs

Chronometer = Clock

Spectacles = Eyeglasses

Chrono = Watch

Conservator = Refrigerator

Caf = Coffee

Nerfburger = Hamburger

Blue milk = Milk (literally blue)

Hubba chips = French Fries

Sweet roll = Doughnut

Flatcakes = Pancakes

Tabac = Tobacco

HoloNet = World Wide Web

Holovision/HoloTV = Television

Holodrama/Holovids = Movie/Videos

Holocamera/Holocam = Camera

Holomap = three-dimensional map

Holojournal = Newspaper

Holocube = Picture frame

Holotable = Projector

Holoscanner = X-ray machine

Holojournalist = Reporter

Flatholo/Holograph = Photograph

Sonic Damper = Active Noise Cancellation

Refresher/Fresher= Bathroom

Sonic Bath = Bath

Sanisteam/Sonic shower = Waterless Shower

Hydrospanner = Wrench

Hydro Flask = Water Bottle

Power Cell/Energy Cell = Batteries

Authorization Chip = Decryption key

Datatape = Disk

Datastick = Flash drive

(Personal) Com Code = Phone number

Datachip = SD Card

Synthflesh = Synthetic skin

Glowrod = Flashlight

Sparkstick = Match

Slugthrower = Gun

Slug = Bullet

Vibroblade = a blade that can vibrate at high frequencies, increasing its cutting power and penetrating ability (tactical knife)

Rangefinder = Rifle scope

Turbolaser = Cannon

Ion pike/Vibropike = Spear

Electro Staff = Stun baton

Blaster = Pistol/Rifle

Stun Blaster = similar to a Taser

Landspeeder/Airspeeder/Speeder = Car

Turbolift = Elevator

Slideramp = Escalator

Starfighter = Fighter jet

Rotorcraft = Helicopter

Hoverpack/Jetpack= Jet pack

Speeder Bike = Motorcycle

Skylane = Traffic lane

Railspeeder/Hovertrain = Train

Power Chair/Hoverchair= Wheelchair

Windscreen = Windshield

Podracing = Car racing

Dejarik = Chess

Sabacc = Poker and Blackjack combined

Galactic Rebels = Combat simulator

B'shingh = Dungeons and dragons

Jizz = Jazz music

Wailer = Singer (ie. Jizz Wailer)

Cantina = Bar or Pup

Para Sailing = Paragliding

Aurebesh = Alphabet

Credits = Money

Sleeping Pallet = Bedroll

Naming Day = Birthday

Youngling = Child

Galactic Basic Standard/ Basic = English

Medkit/Medpac = First aid kit

Hypo = Syringe

Medic/Healer = Doctor

Medcenter = Hospital

Bactapatch = Bandaid

Nanoweave = Fabric

Transparisteel = Glass

Plastifoam = Packing material

Durasteel = Steel

Plasteel = Plastic

Duracrete = Concrete

Slicer = Hacker (slicing = hacking)

Identikit = Passport

Minder = Therapist

Synthleather = Vinyl

Viewport = Window

Cooling Unit = Air-conditioning

Honeydarter = Bee

Slythmonger = Drugdealer

Spice = Drugs

Stimpill = Caffeine pill

Power Socket = Plug

Cutters = Scissors

Cycle = Day

Standard Cycle = 24h

Standard Week = 5 days

Standard Month = 35 standard days

Standard Year = approx. ten months

Tenday = literally ten days

Cigarras/Smokes = Cigarettes

Click = Kilometer or 'a moment'

Parsec = a unit of distance

Tweezers/Clanker/tin head/tinnie = Droid

Separatist = Seppie

Promise Ring = Wedding Ring

Body Glove = Jumpsuit

Slicksuit = Wet suit

Civvies = Civilian clothing

Carbonite = a metal alloy used to freeze a person in a state of hibernation

Hyperdrive = device that allows a starship to travel faster than lightspeed

Moisture vaporator = device that can extract water from the air, commonly used on tatooine

Glareshades = Sunglasses

Gasser = Gas Oven

Repulsorlift = technology that can create an anti-gravity field and is used for levitating heavy objects

Heating unit = Heater

Utility Droid = Roomba

Sunbonnet = a Clone trooper helmet

Bad Batcher = a defective Clone Trooper

Banthabrain = birdbrain/ a stupid person

Bantha fodder = waste of space/nonsense

Blast! = word of exclamation

Blasted! = s.o in anger or annoyance

Blaster-brained = dimwitted

Blaster fodder = cannon fodder

Blast off = Piss off

Brainless = Stupid

Bug/Bugger = used to refer to Geonosians

Forceforsaken = godforsaken

Full of Poodoo = full of shit

Poodoo = Shit

Kriff = Fuck

Jedi scum = derogatory term for jedi

Kark = derogatory expletive

Larty = LAAT/i gunship

Laserbrain = insult

Meat droid = derogatory term for Clone Troopers

Redrobes = Palpatines guard

Rookie/Shinie = newly recruited Trooper

Scum = insult to refer to bounty hunters/rebels

Sharpie = Sharp-witted

Sithspawn/Sithspit/Hellspawn! = expletive

Sleemo = Slimeball

Son of a bantha = insult

Wizard! = Cool

Spaced = dead

Hutt-spawn = Bastard

Karabast = exclamation of dismay

Stang = Crap

Buckethead/Bucketbrain = derogatory term for Stormtroopers

Bucket = Helmet

Nat-born = Natural Born

Roger Roger = affirmative/copy that

Droid poppers = EMP grenade

Sitrep = short for situation report

Backwater Planet = any planet that isn't part of the core system

Holocron = device that can project a three-dimensional image of a person/object and is used for communication or entertainment.

Kessel Run = a risky Operation. Commonly used as a metaphor in impossible situations.

Thermal Detonator= device that can create a powerful explosion like a grenade or bomb

Ray Shield/Energy Shield = creates a (protective) barrier

Rebreather = device that allows a person to breathe underwater or in toxic environments

Phrases:

Wild goose chase = wild bantha chase

That's bantha shit = that's bullshit

As slippery as a greased Dug = untrustworthy

Credit for your thoughts = penny for your thoughts

Cut the poodoo = cut the crap

to get your gills in a twist = get upset about something

Holy mother of meteors = holy mother of god

Oh my skies/ Oh my stars = exclamation of surprise

Stars' end! = exclamation of disbelief

What in the blue blazes = exclamation

When Geonosis freezes over/When it snows on tatooine = extremely unlikely

Who pissed in your power supply = who pissed you off

Blast it = damn it

By the maker = exclamation of surprise

Great karking Dragon = expression of disbelief

Lothcat got your tongue = equivalent of 'cat got your tongue?'

Sod it = expression of frustration