#junk DNA
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TSRNOSS. Page 192.
#junk DNA#heterozygosity#inbreeding depression#enhancers#transcription rate#brush fires#camp fires#mutagens#corridor effect#molar absorptivity#methylene blue#NADPH#lipid synthesis#satyendra sunkavally#manuscripts#notebooks#diaries#cursive handwriting
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what if jusnk DNA isn't actually nonsense, but rather is God annotating their code
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ST Junk Journals [5]: Billy Hargrove
#i promise i’m done fixating on these now lmao#i can’t think of anyone else when i listen to this song#song: DNA by Lia Marie Johnson#billy hargrove#billy antis dni#eyes like yours can look away; but you can’t stop DNA#billy hargrove edit#🌌 — e d i t s#st junk journals
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daily may day 25: descent
girls in their 20s when they have tummy aches 😢
#original#tm2#ocs#daily may 2024#sapote#1 like=1 tums 4 her#I am of course kidding abt the problem being a tummy ache the problem is incompatible animal dna from a different world#I’m sure tummy ache COULD be a symptom considering she lives on junk food and alien booze but who’s to say#could be unrelated#totally not channeling my own reoccurring tummy problemz here …😔
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make your own fate to the best of your ability. that's all any of us can really do.
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happy birthday Ellie and Soapy 🗣🗣🗣
#Aka my spotify repeat 🗣🗣🗣🗣#Junk DNA has vibes im not even gonna pretend its not such a movie soundtrack vibe#and their art 🤌🤌🤌#black&blue definitely ending up top 10 on my wrapped
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this is absolutely wild. ignore the quantum elements. i didn’t know microtubules did shit beyond like. architecture and chromosome wrangling.
#i do believe microtubules are involved in consciousness tho because as we all know nothing is easy and that would make trying to understand#brains so much harder. like pre human genome project when they didnt even know about epigenetics. people used to believe in junk dna.
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Mercredi
Music to upgrade your DNA to? Music in the streets of Barcelona or over there Music to move you Frequency, energy and vibration Nothing is still, time isn’t real, the moon and sun are much closer than we are programmed ( see also conditioned/indoctrinated/ brain washed ; ))to think and much more more ; ) All is atom Over to you, boys!
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#Be loving#Be true to yourself#DNA and consciousness#Do get caught up in their divide and conquer games#Do it#Don&039;t get caught up in their divide and conquer games#Everything to play for#Fortune favours the bold#Let your heart decide today#Nothing else rings like the truth#Nothing is lost#Now#Read Marcus Aurelius#The natural immune system cannot ever be improved upon by big farmer!#The shift started#The truth tide is unstoppable#There are no sides#There is no &039;junk&039; DNA#Truth comes at you like a fox in the dark#upgrade your DNA#we are all one#We win#We won#Wherever there is light there is dark#Win big#You are loved#Your heart and brain coherence is key
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Irondad fic idea that I may or may not (probably not) write:
Tony is helping Peter and May sort through their old junk, comes across photo album with a pic of Mary in it.
Tony, sheepishly: “Peter… I think I slept with your mom”
Peter: “you WHAT?”
Tony, very awkward: “sorry kid”
Peter, evil grin: “I’m telling May!”
*cue race to May a few rooms over. Tony slips on the hardwood in his socks, and Peter, being sticky, has no trouble beating him there*
Peter: “MAY MAY GUESS WHAT?”
May: “what is it honey?”
Peter: “TONY SLEPT WITH MY MOM! He’s a walking ur mom joke!”
Tony arrives, out of breath.
May, glaring: “Stark. Explain.”
Tony, somehow even more awkward than before: “biotech convention, 2000. She flirted with me, and I was- god, I was really drunk. I’m sorry, I would have said something if I’d known.”
May, looking between them and doing some quick mental math: “you two need a DNA test”
Peter: “haha as if”
*cut to Peter and Tony looking flabbergasted at the results*
Tony: “what”
Peter: “the”
Tony: “actual”
Peter: “FRICK?“
Tony: “kid, I think this deserves a fuck”
Also Tony: “this gives me the perfect excuse to pay May child support!”
#iron dad#spiderson#irondad and spiderson#tony stark#peter parker#may parker#bioson au#Peter Parker is Tony Stark’s biological child
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The Research Diaries of S Sunkavally, p 653.
#superoxide#ultraviolet light#melanin#photo-detachment#phytic acid#vitamin D#B-propiolactone#fever#hunger#metronidazole#histone content of thymus#globulins#solubility in water#fibrous protein#junk DNA#hybrid enzymes#hybrid vigour#manuscript#handwriting#satyendra sunkavally#theoretical biology
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Made myself emotional over the “Leo and Donnie chose to be twins” headcanon.
———
“By the way, it’s Leo and Donnie’s birthday next Thursday. You’re coming, right?”
Draxum looked up from his work organizing next week’s lunch schedule to look at Michelangelo, sitting on the counter and swinging his feet. Celebrating individual birthdays wasn’t a thing that the yokai did, but Draxum had been forced to accept that the boys could not be dissuaded from this human tradition. He’d been to two birthday parties now, for Michelangelo and Raphael respectively, eating cake and presenting them with some small trinket he purchased.
He’d known that he would have to go to more birthday parties at some point. But he wasn’t expecting two at once.
“Why on the same day? I can’t imagine the blue one wanting to share.” Actually, he couldn’t imagine Donatello wanting to share, either.
“Oh,” said Michelangelo with a laugh. “That’s ‘cause they’re twins!”
Draxum stared at him. “Twins? What kind of nonsense is that?”
Mikey tilted his head. “What do you mean?”
“They’re entirely different species, for starters,” Draxum pointed out.
“I mean, we all are, but we’re still brothers.”
“Yes, by virtue of your shared DNA donor and the circumstances of your raising.” Draxum waved that off. “But “twins” refers to a situation where two children are born at once, especially as the result of a split of a fertilized egg. Which is absolutely impossible in the case of Leonardo and Donatello. Even if I were to be charitable and simply consider them “twins” for having the same hatch day, I can tell you they do not.”
“Uh, okay,” said Michelangelo, unimpressed. “But they’ve always been twins, so I don’t think it matters to them.”
“Why not? I would think it would matter to Donatello especially, since he claims to be scientifically minded.”
Michelangelo laughed. “Not everything is about science, Barry. Not even to Donnie.”
“Then his decisions about when to apply science and when not to are inconsistent and confusing.”
“Well, it’s their birthday, so they get to pick.”
“I am certain that is not how birthdays work.”
“It’s how it works for us!” Michelangelo slipped off the counter. “We’ll see you on Thursday, right? It’ll mean a lot to them if you come!”
Draxum was fairly sure Leonardo in particular would prefer he didn’t, but that didn’t matter. Now he had a mission: he had to correct this strange incongruence.
“Yes, I will be there.”
“Yay!” cheered Michelangelo. “Okay, see ya Dad!”
He squeezed Draxum around the waist on his way out. Draxum was finding he didn’t mind that as much as he used to.
———
Leonardo and Donatello’s party was just as loud and obnoxious as the other two. Blue and purple decorations covered every inch of the old subway station, strange music blared from unseen speakers, and a horrendous amount of junk food was spread out over a table. It was the same group of people present today as there ever was, the eclectic mix of humans and yokai that the boys considered family, but it felt like a crowd three times the size with the amount of noise being made.
Draxum stood off on his own for most of it, his slim birthday present already delivered to the table stacked with gifts. He’d been a little shocked when Donatello and then Leonardo came by to say hello, since he’d been prepared to be ignored by both of them. It was… nice, maybe, that they did that. Even if Leonardo just wanted to make jokes at his expense.
For most of the party, the two birthday boys seemed to be competing with each other for attention. In fact, the longer he took it all in, the whole affair seemed like a clash of ideas. The purple decorations were neat and tidy, geometric patterns and hard angles. The blue decorations were whimsical, uncoordinated, and haphazard, and there were places it seemed someone had deliberately covered up some of the purple with the blue. Leonardo wanted to play rock music and Donatello wanted to play techno. The cake was a mess because they’d both requested different themes for the decorations. There were arguments between the two of them every few minutes, and according to the human girl April this was “typical behavior.”
But why? They weren’t really twins. They didn’t have to share this day.
Hopefully Draxum’s plan would fix all this nonsense.
When it was time for gifts, Leonardo loudly declared that he was going first, sparking an argument. They squabbled for a bit before agreeing to play rock-paper-scissors, which was apparently what they did every year.
Leonardo won the game and celebrated obnoxiously while Donatello scowled at him. Then he gestured at the gift table - which Draxum, in his efforts to stay out of the main throng, was closest to.
“Hey, Barry! Grab me a gift! Make it a good one.”
Draxum sighed but reached over to take one of the blue packages, checking the tag to make sure it was for Leonardo. “This one is… to Leo from Donnie,” he read.
“Oh no, not that one. Our presents to each other are always last.”
“Because they always get sappy about it,” said April with a laugh.
“Do not!” yelled Leonardo at the same time Donatello hissed, “You take that back!”
“Uh, yeah you do, and you know I’m right.”
Draxum ignored the petty argument to look back at the gift table. If they weren’t going to be satisfied with his choice, he might as well give them his own gift.
He lifted it, in its sensible brown packaging, off the table and handed it over.
“Why not start with this? It’s to both of you from me.”
“Both of us at once?” asked Leonardo. “Oh man, you’re throwing off our whole system, Barry.”
“Yes, but he’s giving it to you,” Donatello pointed out, “which means my turn is still next.”
“Uh, no, if it’s for both of us then it counts for both of us, which means it comes back around to me!”
“Ooooh no, you do not get to loophole your way into opening two presents in a row-“
“Ahem!” Draxum loudly cleared his throat, getting their attention. “Would you please just open it?”
“Yikes,” said Leonardo. “Touchy.”
“Some people just don’t understand the sanctity of opening birthday gifts,” said Donatello with a sniff. But he leaned in to watch as Leonardo tore off the wrapping paper and opened the box.
They were both silent for a moment, staring at it. Then Leonardo said, “Uh, no offense, Barry, but what is this?”
“It’s a… scientific study on how twins are formed during the gestational period,” said Donatello, pulling the paper clipped thesis from the box. “Oh, there are more in here… Also about twins.”
“Uh…” Leonardo blinked at it, clearly bewildered. Well, he was always a bit slow. “Thanks…? I think?”
“Not that I don’t appreciate the scientific literature,” said Donatello, “but this isn’t really my area of study and Leo does better with training manuals and textbooks than research papers.” He looked up at Draxum. “Is there something about this we aren’t getting?”
“Yes there is,” said Draxum, sweeping his hand around at the entire party. “I am here to correct your mistaken assumption that you are twins.”
The room fell silent. Donatello set the paper back in the box, staring at him. Leonardo’s brow creased in anger.
“We are twins, though,” he said, setting the box aside like it was burning him.
“No, you are not. There is simply no way that the two of you could be twins. It is biologically impossible.”
“You think that I’m so stupid I don’t know that?” Donatello demanded, getting up from the chair he was sitting in. “Are you doubting my intelligence?”
“Yes, if you honestly think you are twins with him, then I am.”
“Uhhh, Draxum,” said Michelangelo quickly, stepping between him and the now furious Donatello, “this was a… funny joke, but you can stop now-“
“This is not a joke. I am simply explaining the facts.”
“Yeah, well,” now Leonardo was on his feet, too, “the facts are that me and Donnie are twins. Always have been, always will be.”
“You are not,” Draxum insisted. “And given what I have seen here today, I’d think you’d both be relieved, since you clearly don’t enjoy being twins!”
Both boys looked like they’d just been slapped in the face. The rest of the room had gone completely silent, like everyone was collectively holding their breath.
Donatello broke first, turning on his heel and marching out of the room, his hands balled into fists and his shoulders hunched up as high as they could go. “Dee!” called Leonardo, and then he was scurrying off after him. There was the sound of a heavy door slamming, then silence.
It didn’t last long.
“Draxum!” roared the rat, actually getting up from his chair to get in Draxum’s face. “You come in here and upset my boys on their own birthday!?”
“Seriously not cool, Drax,” said the human April. Cassandra shook her head in shared disappointment behind her.
Draxum pushed Lou Jitsu back, scowling at his accusers. “I was only explaining reality! This is really the rat’s fault for letting their delusion go on so long.”
“Delusion!?”
“Barry!”
“Rat!?”
“Ooookay,” said Raphael suddenly, stepping his way into the middle of the fray and starting to herd Draxum back toward the exit. “That’s enough of that for now.”
“I am simply trying to explain-“
“Trust me, hoss, you wanna step away from this one,” said Raphael, and his tone was angry but surprisingly measured. “Come on.”
They retreated to the sewer tunnels outside the subway station. The smell was much worse out here, and Draxum wrinkled his nose.
“Alright.” Raphael heaved a sigh, folding his arms. “So here’s the deal. Mikey likes you, and I guess I kinda do too, so I’m gonna try to help you before you completely torpedo your chances with the rest of the guys. Which, you kinda did already, but maybe we can turn it around.”
“I still don’t understand why they’re so upset,” said Draxum. “Surely it was obvious they aren’t twins.”
“Uh, yeah, they know they aren’t twins by bio-whatever,” agreed Raphael. “They ain’t stupid.”
“Hmm.” Draxum turned up his nose. “Donatello isn’t stupid, maybe.”
“Leo ain’t stupid, either, he just pretends like it.” Raphael pinched his brow. “Listen, that isn’t the point - the point is they already know they didn’t come from the same egg or hatch the same day or whatever. They’re just twins anyway.”
“But how? That doesn’t make sense!”
Raphael sighed again. “Alright, look. Dad didn’t know when we hatched, right? But we all wanted birthday parties like we saw on TV, so he let us pick.”
“Yes. And for some reason Leonardo and Donatello chose the same day.” Draxum could figure that much out on his own.
Raphael nodded. “I was the biggest and oldest, and Mikey was the littlest and youngest, and Leo and Donnie were just kinda sandwiched in the middle. I think at first they just wanted a thing. Somethin’ that set them apart from me and Mikey, ya know?”
“Not really,” said Draxum. Raphael glared at him, and he sighed. “But go on.”
“So they picked the same birthday and called themselves twins. I think Pops just so glad they were actually getting along that he agreed to it. And I think he thought once we got to the day, and they realized they were really gonna have to share it, they’d both demand their own day instead. I know I thought that was gonna happen.” He smiled at the memory. “But the day came, and… they fussed the whole time just like they do now. Arguing about what kind of cake they wanted and who got to open their present first. But they didn’t ask to split. They kept it the same day, and they kept calling each other twins and it just stuck, until we didn’t question it anymore.”
“…They are both stubborn,” Draxum pointed out, and Raphael laughed once.
“Yeah, guess they are. But that’s not what this is.” Raphael shrugged. “They chose each other back then. Maybe at first it was just to have a thing, but then it became real. And every single year they keep choosing each other. That’s why they’re twins.”
Choosing each other as twins… Draxum furrowed his brow. “It’s not normally a choice,” he pointed out finally.
“Yeah, well, our family doesn’t get a lot of choices, so just let ‘em have this one, okay?”
“…Fine,” Draxum finally relented. “As long as it’s noted that this is purely a social designation, and not a biological one.”
“Uh, sure, whatever.” Raphael rolled his eyes. “Glad we got that cleared up, though. Think you can come back to the party and behave?”
Draxum wrinkled his nose at that phrasing, but nodded. “Yes. I will not bring it up again.”
“Good!” Raphael’s smile abruptly transitioned into something much more dangerous. “Because if you make my little brothers upset on their birthday again, I’ll remind you what it was like when we were enemies.”
Then the smile was back. “Now let’s go in!”
He walked back to the subway station, leaving Draxum to follow on his own. Draxum couldn’t help but sigh wistfully.
Raphael would have made a great general for his army.
———
The boys had already returned by the time Draxum got back. They were opening more gifts, and he noted they were wearing hoodies now - though they had apparently decided to swap their signature colors. They were smiling and chattering, and any hint of their earlier upset was gone.
Until Draxum stepped into their line of sight, and both of them went rigid, wary of him.
Apparently just talking to the red one was not enough. Draxum would have to do more. What a pain.
But he didn’t want the boys to hate him. So he sighed and launched into it.
“I… am sorry. I shouldn’t have said you aren’t twins.”
The boys looked surprised at that; slowly, their posture loosened back up.
“And… to make up for my present, I will… take the two of you wherever you want to go in the Hidden City.” The next words were painful, and he ground them out. “My treat.”
Leonardo and Donatello shifted their gaze from him to each other. They were silent, but it didn’t seem like they needed to talk to have a conversation.
Then they finally looked back at Draxum, slow grins growing over both their faces.
Eerily matching, very evil grins.
“Oh,” said Leonardo, happily menacing. “I think we can think of something.”
“I concur,” said Donatello in the exact same tone.
Oh, thought Draxum. Maybe they really are twins.
#dandy fanfiction#rottmnt#rise Leo#rise Donnie#rise raph#baron draxum#rise Mikey#disaster twins#I didn’t proofread this haha#I love the twins being twins by choice#Donnie and Leo had a big sappy talk sorry it was off screen
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Prompt: Gotham Baby Switch Mystery (DCXDP)
Gotham City is in chaos. Major breaking news has just surfaced: a nurse or doctor (your pick) has been involved in switching the identities of nearly 200 babies over the course of their career. Gotham PD, working overtime alongside other police departments, has been investigating the swaps. The authorities now have a list of affected families, and the shocking implications are that the child you’ve cared for, loved, and raised with all your heart may not actually be yours. Worse yet, the child you buried may also have been someone else’s.
Among the families affected? The Wayne family. And, understandably, the Batfamily is freaking out. The questions are piling up: Does this mean we have a brother or sister out there in the world? Why hasn’t Bruce told us about this? Chaos ensues.
Bruce Wayne, however, is left with only one certainty: the child he and Talia al Ghul had together, a baby born prematurely. The child spent days in the ICU, and the doctors were hopeful, but ultimately, the baby passed away. That tragic event had driven a wedge between Bruce and Talia, and she cut ties with him. When she became pregnant with Damian, Talia did everything in her power to ensure that her second child would survive to term, determined not to lose another baby like their first.
Faced with the turmoil of this new revelation, Bruce does the only thing he can think of: he calls Talia. He tells her about the baby swap scandal and asks if, given the news, she’d like to meet the child who might be their lost son or daughter. Talia, understandably, is furious. Her emotions boil over. The trauma of burying her child, only to now be told that the baby may not have been hers at all, is too much to bear. Her first instinct is to kill the person responsible for causing this pain.
Still, Talia decides to take Bruce up on his offer. If the League of Assassins and Batman work together to gather information, she wants to know the truth. And of course, Damian has just discovered that he may have an older sibling—and he’s determined to meet them first. He’s not going to let anyone else in the family get to them first, calling dibs on being the first to see the once presumed-dead sibling.
Two months had passed, and there was still no new information about where in the world Bruce and Talia’s child was. However, since the news had broken in the U.S., many of Bruce’s friends had stepped in to help. Lex Luthor and Oliver Queen suggested that Bruce's child might have taken a DNA test, as it was becoming increasingly popular among adopted or orphaned individuals who wanted to find their birth parents or potential siblings—whether through sperm donation or other means.
That’s when they discovered that a 14-year-old kid from a small town in Illinois had done a DNA test. This was how Bruce, Talia, and the Bat family found out that their lost sibling—whom they all assumed was a boy—was alive. The confusion had arisen because, when she took the test, Danny had used her nickname, Danny Fenton, rather than her full name, Danielle Fenton, which led everyone to assume she was male. In contrast, Jazz, her older sibling, had written her full name—Jasmine Fenton—on her own test. So, when the Bat family found the results, they expected a boy but were unaware that Danny was, in fact, a girl.
However, Danny and Jazz’s parents, Jack and Maddie Fenton, had never opened the letter containing the letter explain the whole affair. . It had been sent to the Fenton household, but it was discarded as junk mail, with the Fentons assuming it was another complaint about their family, specifically Jack and Maddie’s eccentric, often controversial, scientific endeavors. No one realized the importance of the letter until much later.
The test results showed two key revelations that shocked both Danny and Jazz. First, the two were not biologically related at all. They were not sisters by blood. Second, the test revealed that one of Danny’s biological parents had Middle Eastern ancestry. This was a detail that Danny hadn’t known, nor had she ever suspected.
Meanwhile, as Danny was undergoing a strange and painful transformation, gaining her ghost powers and becoming a half-ghost, she unknowingly shared this moment with a significant event taking place far from Amity Park. On the other side of the world, John Constantine was battling demons. During one such fight, a particular demon expressed an intense fear, saying, “Are we really going through with this? I thought Lady Gotham would never agree to it. Hell, most of us demons don’t want to deal with her wrath.”
Constantine, intrigued, asked, “Why would a demon like you be afraid of Lady Gotham? I’ve met Batman and his insane family, and honestly, half the time, I don’t even believe they’re mortal. But what does Batman have to do with you? He doesn’t even know you.”
The demon paused, clearly shaken. “There was an event where Cronus ( Clockworks) called together all the demons, all the powerful beings, into the infinite realms. During that meeting, Cronus ( Clockworks) revealed one truth: the Ghost King will wake from his slumber. And only a warrior—not from the land of the living, nor from the Infinite realm—will be able to defeat him. This event will happen in every timeline Cronus has seen. But the parentage of the warrior changes with each timeline. This time, the warrior’s parentage is what scares us. Nobody wants to see the wrath of Lady Gotham.”
Constantine narrowed his eyes, sensing the gravity in the demon’s words. “What are you talking about?”
The demon continued, fear lacing its voice. “The decision that was made—bringing this individual, this warrior, into the fight—has caused a ripple effect across the ancient realms. Some of us, those who are eternal, those who have never known death, have already overstepped. Even some of the observers—beings who are supposed to remain neutral—have meddled. Now we have to deal with the consequences of our actions. And it’s not just us. It’s the entire infinite realm. We’re all doomed. Let us pray, Constantine, that the Ghost King never awakens. For when he does, and the warrior defeats him in single combat... that will be when all of our fears come to fruition. It will be the beginning of the end.”
Constantine’s stomach turned as the weight of the demon’s words settled in. “You’re serious, aren’t you?” he muttered under his breath.
“Deadly serious,” the demon replied. “What they’ve done… is beyond repair. And the worst part is, they didn’t even realize it. The actions of the living—specifically Lady Gotham and her vigilantes—have overstepped a boundary. The warriors of Gotham, the protectors, the police, the citizens—even the Joker—are all unknowingly playing a part in this colossal mistake. It wasn’t Darkside, or any of the other cosmic threats or even Supernatural threats that you and those Heroes have faced, that will bring about the end. NO It’s this one misstep. One moment of carelessness. One action, and now it’s too late.”
Constantine stood there, his mind racing. “This prophecy... It’s not just about one person, is it? It's about the whole damn city, the whole damn world.”
The demon nodded grimly. “Gotham is the key. And once the warrior rises, once the wrath of Lady Gotham is unleashed, nothing will stop it. Cronus himself is holding an emergency meeting about this, trying to figure out how to deal with it. And let me tell you—things are not looking good for anyone.”
Constantine cursed under his breath. He realized that the situation was far worse than he could have ever imagined. If the demon was right, and this prophecy was truly tied to Gotham, then they were all in serious trouble. And what terrified Constantine the most was the thought of Batman finding out that someone—someone he loved—was being manipulated, consciously or not. Batman didn’t care about the methods or the reasons; if anyone he cared about was caught up in a scheme like this, the consequences would be catastrophic.
“God help us,” Constantine muttered, more to himself than to the demon. “Because if this gets back to Gotham… none of us are getting out of this alive.”
So if this post gets a lot of likes I will make a part 2 continuing the story. Because this is something that has been stuck in my mind I just want to share it.
#dp x dc#danny phantom#dc x dp prompt#john constantine#female danny#batfam#damian wayne#damian al ghul#cassandra cain#talia al ghul#Gotham baby mystery
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Mulder's Brain Disease: an Open-Minded, Analytical Dissection (In-Depth)
Mulder's brain disease, love it or hate it, has to be one of the most unnecessary plot threads of The X-Files. Not only is it wedged into Season 8 haphazardly, but it accidentally stains a new wash of retroactive interpretation into Season 7-- a not altogether successful maneuver, all told.
Most of the canonical evidence provided clashes with itself, many of the details volunteered undermine its collaborative vision, and each piece of action or exposition is either forwarded with the assumption of legitimacy-- and therefore unchallenged-- or immediately discredited in the next scene or scenes.
There are two clear paths and one alternative to explore: Mulder didn't have brain disease (per Season 7's original intent); Mulder did have brain disease but didn't tell Scully (what Agent Doggett is led to believe); and Mulder had brain disease but didn't know it.
Let's begin.
STATEMENT(S) OF (ALLEGED) FACT
The X-Files is well-known for its... questionable timelines. That becomes exponentially more complicated with Season 8's tightly wound schedule and Scully's pregnancy (which Spotnitz and Carter stuck to rather well-- barring a few logistical hiccups-- post here.)
The brain disease arc inflexibly hinges on a retroactive retelling of Season 7's schedule. One chronological bookend is Amor Fati (stated to have taken place "in the fall"); and the other is the month of May: Mulder takes "four consecutive" road trips to North Carolina, allegedly pops over to Squamash Pennsylvania (twice), and supposedly buys himself a new headrest (read: gravestone)-- all within the span of four weeks. Additionally, we have allegations of a year-long brain disease-- despite all evidence to the contrary-- which places Mulder in a position of secret keeper or liar by omission (which CC has vehemently denied, post here.)
BRAIN DISEASE
(**Note**: This section's information will be summarized under the "FACTS AND FICTION, THOUGHTS AND THEORIES" subsection.)
Requiem builds on top of the "encephalitic trauma" Mulder experienced in Biogenesis-Amor Fati-- one that, we're told, made him "more alive than he's ever been." So alive, in fact, that his body couldn't support itself and shut down; and so alive, in fact, that CSM cut out a part of Mulder's lobe and Frankensteined it into his own.
The show's mythology set up the alien-human virus as early as Season 3, and built upon that foundation with the characters' subsequent adventures in Fight the Future, The Beginning, and Biogenesis. As a virus, it grafts onto human DNA and changes it-- or in this case, reactivates from junk DNA. As Dr. Anne Simon, a consultant for The X-Files, explains:
Jan. 2001:
"...I work on viruses. Viruses can’t turn into anything. If a virus turns into something, it’s not a virus. I was really horrified. So I read the rest of the script, and I came up with a different science that would only change a few conversations, but it would change the idea of what the virus was. And I had my fingers crossed that he’d go for it. If Chris wanted that virus to turn into something, he would’ve done it whether I wanted it to or not. But he loved the new idea: The virus integrates itself into the DNA of the person. That’s what a lot of viruses do, activate a resonant program in the cell. There’s a program in all our cells, in our DNA that starts with that single egg and turns us into a person. And that’s encoded in our genes, in our genetic makeup.
"The problem is that there’s a huge amount of DNA we don’t have a clue about. There’s a whole lot of DNA that we call junk DNA. We don’t have a clue what this junk DNA is doing. My idea was the virus activates a resonant program in the junk DNA, and that the junk DNA is actually there to turn a cell into the horrible creature, which means that we are the aliens."
Point taken. Multiple (questionable) vaccine inoculations and infections aside, humans in The X-Files world have latent alien DNA. The ancient artifact Mulder handled in Biogenesis activated his; and, unable to bear up under that extremis, his body was reduced to catatonia and shut down. Though there are quite a few problems with that specific chain of events (most of which I discuss in an alien virus post here), the logic could, theoretically, hold up.
ENCEPHALITIC TRAUMA AND REWRITES
In Amor Fati, Mulder was so far gone that he'd disconnected from reality (although his "inner" world was still influenced by outer events.) How, then, was Mulder brought back from the land of fantasy? Metaphorically, it was through Scully's belief and love and courage; practically, it was because of the (successful) medical procedure he underwent during his captivity (post here):
RULING OUT: TREPANATION AND BRAIN EDEMA
Two possible causes for Mulder's later complications need to be explored before we move on.
Firstly, as with a great deal of other components on the show, trepanation is not as simple as the writers propose:
World History.org, here:
"Trephination (also known as trepanning or burr holing) is a surgical intervention where a hole is drilled, incised or scraped into the skull using simple surgical tools. In drilling into the skull and removing a piece of the bone, the dura mater is exposed without damage to the underlying blood-vessels, meninges and brain.
According to Academic Press's 'Osteoarcheology': "A neurosurgeon can perform the procedure safely, although it comes with severe repercussions such as direct or indirect perioperative complications, which include increased damage to the brain, infection, blood loss, hemorrhage, and potentially death due to the trauma as the skull's protective covering is compromised."
Here, its perils are hand-waved away with "advanced alien science"; but to potentially complicate Amor Fati's explanation, the purpose of Mulder's surgery was to slice out an activated portion of his brain and transfer it to CSM's:
Penn Medicine, here:
"A temporal lobectomy, or temporal lobe resection, is a neurosurgical procedure that removes the front part of the temporal lobe of the brain to treat drug-resistant epilepsy. Each person has two temporal lobes, located beneath the skull on the side of the head in the temple region. The temporal lobes play important roles in memory, emotional responses, language, and sensory memory and processing of sounds, visions, and smells."
While it's possible that Mulder's and CSM's declines could have been kick-started by this procedure, that's not the route canon follows. Spender's deterioration is tied to "cerebral inflammation", which in turn is tied to Mulder's pre-surgery encephalitic distress-- in short, pre-trepanation trauma.
Secondly, the script also details a medical procedure that is most often used to relieve and treat brain edema (brain swelling)--
NHS, here:
"Ventriculostomy: In this procedure, a surgeon cuts a small hole in the skull and inserts a plastic drain tube. Cerebrospinal fluid is drained from inside the brain, helping to relieve the pressure.
Surgery: Surgery may have one or more of these goals:
A. Removing part of the skull to relieve intracranial pressure; this procedure is called decompressive craniectomy.
B. Removing or repairing the source of the swelling, such as repairing a damaged artery or vein or removing a growth."
Brain edema-- depending on the extent and duration of the trauma-- usually inflicts various degrees of harm. And while that could be promising when discussing Mulder's brain disease, Scully would have seen evidence of edema-ridden damage on his CT and MRI scans during his convalescence. Further, brain edema is not a form of brain disease, rather an offshoot effect of that condition-- therefore, not the cause of his (alleged) impending death.
AUTHORIAL INTENT AND REWRITES
Inverse to Mulder's reawakening and restored health is CSM's 30 touch-and-go hours and grim, post-operation prognosis:


His doctor's hints about a second surgical intervention are particularly intriguing. When CSM reappears in Closure, Scully notes his odd pallor-- "You're sick"-- which he doesn't deny-- "I had an operation." We are to assume he is referencing the brain surgery in Amor Fati-- he is-- but I would like to posit Spender could be referencing a possible second procedure (an off-screen attempt to mitigate his ailing health.) By En Ami, CSM's fate is sealed, and he openly admits his mortality in order to ignite Scully's trust (post here): "Cerebral inflammation-- a consequence of brain surgery I had in the fall. The doctors give me just a few months." His arc comes to a close in Requiem (unless you push canon into Season 9 and beyond) where we see the rapid toll of his deterioration.
Recovery from "advanced alien science", then, is aided by regular, everyday human physiology: age, health, medical history, and comorbid influences. Spender's age, smoking status, and former cancer diagnosis all combine against him-- his hubris for power led him willingly to death.
By contrast, Mulder's experience wasn't mentioned again until Requiem when he and the Bellefleur residents-- who'd previously suffered encephalitic trauma-- were called to the ship and abducted. There was no idea, hint, or reference sown about his deteriorating health: not a sign, not a symptom. Yet, mere months later, the tale is retold in Within: we learn, allegedly, that not only did Mulder have brain disease (and not only did Scully not know) but he'd also suffered through it for a year.
Frank Spotnitz admitted, after the close of Season 8, that the brain disease (and the IVF arc) was a last-minute creation he and Chris Carter decided on after their plans for a second movie set post-Requiem fell through:
April 2001:
"In the absence of pre-existing context for season 8’s dramatic surprises, the writers relied instead on flashbacks tailored to fit this year’s narrative. “Had I known there would be a season 8, I would have preferred to salt in all of the clues about these flashback episodes last season,” says Spotnitz of how he dealt retroactively with fitting in Mulder’s illness and Scully’s [IVF]. “But there really is no way to unravel these mysteries in my mind, and make use of David in the time that he was available to us, without having some flashback episodes.”"
Setting aside the complete lack of evidence that would “prove” Mulder was suffering from a degenerative brain disease, silently, for a year (without telling Scully), we’re left with a few bare-bone facts:
Season 7 was not written with the brain disease in mind.
Mulder's "encephalitic trauma" in Requiem was shared by the other Bellefleur residents, who were not (that we know) dying.
CSM declared that he was dying from "cerebral inflammation."
CSM's downturn post-Amor Fati was recorded at key moments through Season 7, with scrutable markers of decline and clear indicators of psychological shifts and changes influenced by his impending death.
In Within, we’re led to believe Mulder was suffering from year-long degenerative damage due to the surgery he and CSM underwent in the fall of 1999. Not only do his actions (or non-actions) in canon contradict this thesis, but Within-The Gift's timeline contradicts it, as well.
Deadalive-Three Words Mulder never confirmed he was diagnosed with-- or knew he was suffering from-- brain disease.
What, then, is "cerebral inflammation"; and how can we work in the brain disease as more than a creative (though flawed) hypothetical?
THE FIRST ROUND OF INFECTION
Encephalitis (“cerebral inflammation”) is pretty straight forward: you either have it and notice, or you have it and don’t.
There are two main types of "cerebral inflammation"--
NIH, here:
Inflammation in the brain and spinal cord can be caused by infections such as viruses. Encephalitis can also be autoimmune when antibodies can attack brain cells.....
NIH, here:
"Because people may have subtle symptoms of encephalitis, many cases may go undiagnosed. Several thousand cases are reported each year, but many more may occur since the symptoms may be mild at onset in some people."
Encephalitis hits fast and hard, disappearing within two weeks (Better Health, here) of its inception. Mild instances can pass through the body undetected; but severe or life-threatening cases are unequivocally transparent:
NIH, here,
"Once the acute illness, which normally lasts for 1 to 2 weeks, is under control, comprehensive rehabilitation should include cognitive rehabilitation and physical, speech, and occupational therapy if brain function is severely affected."
Mount Sinai.org, here,
"Those with a severe case of encephalitis may develop:
High fever
Severe headache
Stiff neck and back
Photophobia (sensitivity to bright light)
Sonophobia (sensitivity to sound)
Vomiting
Drowsiness and confusion
Seizures
Behavioral changes
Muscle weakness
Partial paralysis
Loss of consciousness
"Because encephalitis can on rare occasions be dangerous, it needs to be diagnosed and treated promptly....
"Many people exposed to encephalitis-causing viruses have no symptoms. Others may experience a mild transient illness, but do not develop full-blown encephalitis. People with mild encephalitis generally recover spontaneously over a period of several weeks.
"Severe cases of encephalitis can, however, have devastating effects, including:
Swelling of the brain caused by excess fluid (cerebral edema)
Bleeding within the brain (intracerebral hemorrhage)
Nerve damage (neuropathy)
"Encephalitis is a relatively rare disease. People at highest risk for encephalitis, and its complications include the very young, the very old, and people with weakened immune systems."
NIH, here:
"Because the disease can occur suddenly and progress rapidly, anyone who is suspected of having encephalitis should immediately contact a doctor or go to the hospital.
"...In more serious cases, the disease can cause hearing and/or speech loss, blindness, permanent brain and nerve damage, behavioral changes, cognitive disabilities, lack of muscle control, seizures, memory loss, or death. People with serious cases of encephalitis may need long-term therapy, medication, and supportive care."
Lastly, the risks for serious complications arise with the usual physiological predispositions and environmental factors--
Mayo Clinic, here:
"Anyone can develop encephalitis. Factors that may increase the risk include:
Age. Some types of encephalitis are more common or more serious in certain age groups. In general, young children and older adults are at greater risk of most types of viral encephalitis. Similarly, some forms of autoimmune encephalitis are more common in children and young adults, whereas others are more common in older adults.
Weakened immune system. People who have HIV/AIDS, take immune-suppressing medicines or have another condition causing a weakened immune system are at increased risk of encephalitis.
Geographical regions. Mosquito- or tick-borne viruses are common in particular geographical regions.
Season of the year. Mosquito- and tick-borne diseases tend to be more common in summer in many areas of the United States.
Autoimmune disease. People who already have an autoimmune condition may be more prone to develop autoimmune encephalitis.
Smoking. Smoking increases the chances of developing lung cancer, which in turn increases the risk of developing paraneoplastic syndromes including encephalitis."
In Biogenesis, we are told the alien virus in Mulder's DNA is activated when he touches an ancient artifact; but it's debatable if that incident lines up with viral (infection via an outside invader) or autoimmune (mistaken antibodies attacking its host) encephalitis. Regardless, that question is secondary to the main hypothetical: if encephalitis ("cerebral inflammation") has a short shelf life, what was killing CSM (and Mulder?)
REINFECTION: AUTOIMMUNE ENCEPHALITIS
The problem begins with CSM's (and Mulder's purported) year-long deterioration. "Cerebral inflammation", as explained above, does not drag its feet when swooping in for the kill. And more broadly, how is Mulder able to be reinfected with a disease which old Spender sliced and diced from his head? Better Health.gov's description (here) fits what the writers were going for, I believe: "There is evidence to suggest that some cases of viral encephalitis are caused by dormant viral infection... becoming active again." This plays well with Mulder's initial infection (Biogenesis), as well as CSM's lengthy "cerebral inflammation" and Mulder's (alleged) inflammatory reemergence.
However: recurrence is a symptom of autoimmune encephalitis, not viral encephalitis--
NIH, here:
"Although rare, there have been cases of post-infectious autoimmune encephalitis (where it is triggered by an initial response to an infectious agent)."
Autoimmune encephalitis: a review of diagnosis and treatment, here:
"Viral infections are known triggers for AIE. It is believed that virus-mediated brain tissue damage may lead to antigen exposure that triggers the development of anti-neuronal antibodies."
Another checkbox that can be ticked off: AIE might take longer to diagnose because of the difficulty pinpointing symptoms--
NIH, here:
"Diagnosing autoimmune encephalitis can be difficult as the average onset of symptoms to diagnosis often takes a few weeks to 3 months. ...To diagnose autoimmune encephalitis, we need multiple tools to aid in the diagnosis, although clinical judgment is the key to making decisions. They will include a constellation of neuropsychiatric symptoms, lab studies, neuroimaging, and electroencephalogram."
Slowly-degenerative AIE cases (though infrequent) do exist--
Autoimmune encephalitis: a review of diagnosis and treatment, here:
"By way of generalisation, autoantibody-mediated disorders often present rapidly, over a few days to weeks. However, we have observed more chronic courses, of between 1 and 5 years, particularly in leucine-rich glioma-inactivated protein 1 (LGI1)-antibody, contact-associated protein 2 (CASPR2)-antibody and immunoglobulin-like cell-adhesion molecule 5 (IgLON5)-antibody syndromes. These findings mean that time to disease nadir is often outside of the 3-month duration which appears in diagnostic guidelines."
Nevertheless, atypical cases are often put through rigorous testing to rule out other degenerative autoimmune diseases due to the severity of their symptoms: mood changes, mental confusion, muscle tremors, seizures (focal rather than generalized), pain, psychiatric symptoms, and (more often than not) tumors.
"Autoimmune encephalitis: a review of diagnosis and treatment", here:
"Seizures occur in most autoimmune encephalitis syndromes and are a common factor that triggers neurological attention. The types and frequencies of seizure vary between autoantibody-mediated diseases and may help pinpoint the individual autoantibody. …These patients, typically men in their fifth to eighth decades, have very frequent focal events with multiple semiologies and only rare generalised seizures....
"In addition to treatment of the underlying immunological process, it is often necessary to consider management of seizures, movement disorders, behaviour, pain, sleep and autonomic disturbance, and mood disorders. We do not discuss this substantial topic comprehensively here but rather we focus on special considerations relevant to the two most common forms of autoimmune encephalitis: NMDAR-antibody and LGI1-antibody encephalitis."
It is possible, however, that the extent of the damage Mulder received during his surgery might have been overlooked-- fertile ground for the next trauma-induced biological onslaught:
NIH, here:
"Because lesions can sometimes be clinically asymptomatic, a systematic neuroimaging work-up should be performed.... Cerebral computed tomography scans [CT scans] performed at admission show abnormalities only in 30% of patients, essentially supratentorial readily visible diffuse or large focal hypodensities of the cerebral white matter. MRI of the brain should therefore be systematically performed when post-infectious encephalitis is suspected."
But the basic premise (and same problem) of 'traditional' encephalitis remains. AIE, though possibly reoccurring, does more harm in the short term than the long run: its most powerful weapon is either immediate death or a damaging domino effect--
NHS UK, here:
"Encephalitis can damage the brain and cause long-term problems including:
memory loss (amnesia)
personality and behavioural changes
speech and language problems (aphasia)
swallowing problems (dysphagia)
repeated seizures or fits – known as epilepsy
emotional and psychological problems, such as anxiety, clinical depression and mood swings
problems with attention, concentrating, planning and problem solving
problems with balance, co-ordination and movement
persistent tiredness"
It's not a leap, then, to suppose that--
CSM's health immediately crumbled apart because of his age, health, and smoker status.
Whereas Mulder's health-- if he was affected-- was bolstered up by youth and other factors. However: that does not rule out a potential sleeper agent lurking in his brain, waiting for the next traumatic incident to reactivate, AIE-style. (We'll get to that.)
FACT AND FICTION, THOUGHTS AND THEORIES
The facts, as we know them:
Encephalitis, no matter its form, is not a slow-burn, long-term killer. Yet, the fallout from its destruction can create a domino effect that could, potentially, be lethal.
Regardless of the original diagnosis, CSM and (allegedly) Mulder suffered from autoimmune encephalitis after Amor Fati.
While mild cases can be undetectable, severe or life-threatening encephalitis can't be masked and must be treated promptly.
CSM is doubly or triply immunocompromised-- per his age, past cancer, and on-going smoking habit-- and was promptly affected.
Mulder and the Bellefleur residents were abducted and transformed due to past "encephalitic trauma", not current, prevalent brain disease.
Most importantly: if Mulder and CSM had been dying over a year's time, there would have been conspicuous physical evidence-- evidence which Scully would have detected (as she did in Closure.)
Irrespective of these facts, let's play around with a few hypotheticals.
If Mulder and CSM had been dying contemporaneously, then they would have to be deteriorating from the ripple effects of at least one of three factors:
Extensive brain damage-- which would have become immediately apparent once they woke.
Accumulative comorbidities set in motion via brain damage-- which Spender did, and Mulder did not, have.
Reactivated effects caused by another traumatic incident-- which Mulder could have had (and did) in Season 7.
That last point is a particularly intriguing theory. Mulder would have been suffering profusely had his disease run concurrently with CSM's-- but what if it didn't? What if Mulder's brain disease was a recent diagnosis-- one he'd received before his abduction? If so:
His reticence from Scully would be short-lived and easily explained by Mulder still processing the news.
His sudden rash of trips to his mother's and sister's graves could be influenced by anxiety over an impending medical report or in reaction to an inflexible diagnosis.
His headstone purchase could be explained as a rash, last-minute gesture of acceptance (or could have been faked by his nemeses, which we shall get to.)
Yet, and this cannot be stressed enough: even if Mulder had a recurrence of encephalitis, it alone would not be enough to kill him, just like it alone would not be enough to kill CSM.
To get to the bottom of any and all possibilities, we need to map out a simple, logical, cut-and-dried timeline.
So, let's do it.
CANONICAL (AND RETROACTIVE) TIMELINE
(**Note**: If you don't care to read the discovery process, skip to PUTTING IT ALL TOGETHER.)
To chart a course through the brain disease's cluttered "shoulda, woulda, coulda"s, two options present themselves: episodic air dates, or in-canon date markers.
Here we run into the first problem: neither touchstone works unmitigatedly: either in-canon dates reorder key episodes (perhaps the props department worked off the script rather than day-of filming?) or air dates don't graph cleanly onto defined in-canon perimeters and events. What we'll have to do: nail down the definitives, and work back (loosely) from there.
xfilestimeline.net provides an exquisite guide to (most of) The X-Files's chronological order, which I will be referencing below (direct quotes in italics.)
AMOR FATI
Amor Fati takes place "in the fall" according to Within. The air date (November 14) and in-canon estimate (October 7-14) both roughly group into that space. Mulder is wearing his "victory cap" to come find Scully; but it's hard to know for certain that the hallway scene takes place shortly after the last week of September (which, according to xfilestimeline.net, was the first Yankees victory of the season) or if he simply wore it to cover his bandages and bantered around the obvious.
Either/or is viewer's choice.
SIGNS AND WONDERS
Signs and Wonders's air date (January 23) outruns a "medical report" (January 17-19) by just a few days.
EN AMI
En Ami takes place (comparative to any month afterward) "last spring." Since there is no internal date provided, it either falls on March 19 (its air date) or sometime after February 20 (X-Cops's in-canon date) and before April 14 - May 1/May 8-12 (Brand X - Chimera's in-canon dates.)
Again, viewer's choice.
SEIN UND ZEIT
Sein und Zeit airs on February 6th; but its date is "confirmed" by a TV broadcast of State of the Union Address (January 27 - February 1.)
BRAND X
Brand X's air date (April 16) coincides with its in-canon, two-week recovery estimate (April 14 - May 1.)
CHIMERA
Chimera debuts a full month prior (April 2) to in-canon configurings (May 8-12: Date confirmed at outset ((2 weeks after 4/23)).)
Chimera marks the first overlap between Season 7 and Season 8: Mulder (allegedly) visited Squamash, Pennsylvania on May 6 -7, a day before he and Scully were assigned to a stakeout (May 8.) It's not stated how long Mulder and Scully were on duty before he was again reassigned; but it stretches believability (what else is new?)
ALL THINGS
all things has no fixed internal date, though it's air date (April 9) takes place a full month before the estimated in-canon dates (May 13-15.)
FIGHT CLUB
Fight Club's airing was May 7; but its own internal date (June 17-19) so incontrovertibly contradicts Requiem's abduction timeline that it can be confidently swapped out for May 17-19.
This episode is pivotal to quite a few brain disease theories.
JE SOUHAITE
Je Souhaite air date (May 14) is hastily surpassed by its estimated internal date (May 22-24.)
This episode is vital to understanding the brain disease arc-- more accurately, to understanding Mulder's mind frame when given three wishes.
REQUIEM
Requiem is key to the entire framing of the brain disease arc:
Either Mulder is abducted on May the 21st (Requiem's air date), which shreds through Agent Doggett's May timeline (which will be discussed below);
Or Mulder is abducted on May 31st (the day before Within), which tears fewer rips in Agent Doggett's theory.
Pulling from my "Laying Waste to The Gift (with Its Own Canon)" meta (post here):
A. ...Doggett refers to Mulder's trips as "Four consecutive weekends in May"-- distanced language that (one can infer) means the month is over. (If he and Scully were still in May, Doggett would have more naturally stated "each weekend this month" or "the past four weekends.")
B. Spotnitz has since confirmed Within takes place the day after Scully's reveal in the hospital ("Season eight begins the morning after season seven." Interview here.)
C. Therefore, it's safest to assume Within takes place in June (either June 1st or June 2nd), pushing Mulder's abduction date to May 31st.
WITHIN
Within begins the complete disregard for air dates-- and rightfully so, given the strict guidelines of Scully's pregnancy (post here.)
See Requiem above: takes place June 1st.
PER MANUM
Per Manum takes place mid-September (Scully's baby is fourteen weeks old. Given that she announced her pregnancy to Skinner at the very end of May, it seems likely that she conceived in mid-May, which would give a mid September date for this episode.)
THE GIFT
The Gift is broken into three trips: (allegedly) Mulder, May 6 A.M. - 7 A.M.; (allegedly) Mulder, May 24; and Doggett, late September. (No internal dates provided. It is said to be roughly a "year" since Mulder visited Squamash, but given the events of Episode 8x14: This is Not Happening, it's more like under half a year. Doggett confirms that Mulder was abducted in May. He went to Squamash, PA on May 6-7, and returned there on the 24th. Doggett also reveals that Mulder falsified case reports, which explains how the dates might be off at the end of Season 7.)
This episode is, quite frankly, a catastrophe. I broke down the timeline and its inconsistencies in a previous post, here-- suffice it to say, it discredits its own claims in its own episode. But, we will be returning to this... gem later on.
PUTTING IT ALL TOGETHER
Now that we have a framework for both seasons, we can begin to slot the pieces side by side.
"In the fall", Amor Fati: Mulder and CSM both undergo brain surgery. Mulder fully recovers (or does he?) while CSM deteriorates slowly over the course of a year.
April 14 - May 1, Brand X: Mulder is hospitalized some length of time during his two weeks of recovery. Neither Scully nor the medical staff notice any medical abnormalities (i.e. odd or troubling physical responses, readouts, or charts) despite heavily monitoring his health.
May 6-7, The Gift: Mulder burns up one of his consecutive weekends by (allegedly) taking a trip to Squamash, Pennsylvania on May 6-7.
May 7: Mulder takes his first 370 mile trip (10 hours total) from D.C. to North Carolina and back. He will (allegedly) make three more consecutive weekend drives until his abduction in Requiem.
May 8, Chimera: Mulder has a case ready for he and Scully to investigate (one that likely required the weekend to research-- more on that later.)
May 13-15, all things: Mulder burns up another consecutive weekend on a trip to England.
May 17-19, Fight Club: Mulder takes some heavy hits.
May 22-24, Je Souhaite: Mulder doesn't consider asking the genie-- not once-- to heal his brain disease.
May 31, Requiem: Mulder is abducted due to his "encephalitic trauma", courtesy of Biogenesis's ancient artifact.
June 1, Within: The Alien Bounty Hunter parades around Mulder's life, stealing his (and Scully's) computer.
June 2, Within: Doggett obtains rental car receipts, VISA card purchases, and year-long medical records, thereby coming to the conclusion that Mulder took four consecutive weekend drives (nearly 400 miles, over 10 hours) from D.C. to North Carolina. Doggett and his team do not find Mulder's gun taped under the apartment sink.
Late September, The Gift: Doggett finds a case from last May he and his team had missed. He also finds a bloody gun taped under Mulder's sink that he and his team had missed. He also finds an incriminating report that has Mulder and Scully's name on it that he and his team had missed. He does not check the dates against "Mulder's May Pilgrimages", nor does he corroborate the signatures and evidence with Scully.
Chronological order locked and loaded.
DEBUNKING AGENT DOGGETT'S (ESTIMATED) ITINERARY
Now, let's break down the evidence Doggett "unearths."
SUPPORTING EVIDENCE
In Within, Agent Doggett rests Mulder's brain disease on three rational (and one discredited) facts:
Mulder's surgery "in the fall" (Amor Fati)-- one Mulder did not, apparently, recover from. Doggett and his team discover "evidence" indicating a year-long decline which the files predecessor had kept secret from his medical doctor-partner.
Mulder's "four consecutive weekends" drives to North Carolina ("Same mileage each trip: 370 miles, 375 miles"), which means he either kept them hidden from Scully or she lied to Doggett when questioned.
Mulder's sudden, erratic purchases in May: flowers and a personally-inscribed headstone on the same VISA card.
Mulder's and Scully's missing computers and files (later proven to be the Alien Bounty Hunter's machinations.)
In The Gift, Agent Doggett discovers further "proof" to support his supposition:
Mulder (allegedly) took a trip to Squamash, Pennsylvania to investigate a case on May 6 (Saturday.)
Mulder (allegedly) returned to be healed by the Squamash creature on May 7.
Mulder (allegedly) turned down the opportunity to be healed in order to mercy kill the Creature.
Mulder (allegedly) hid his bloody "murder weapon" (an ankle gun) under his kitchen sink.
Mulder (allegedly) had Scully sign off on his closed report, with or without fully informing her.
Mulder (allegedly) placed his and Scully's careers in danger because of this falsified report... conveniently (post here.)
DESTRUCTIVE CONTRADICTIONS

Problem #1: Doggett Needs Four Weekends
As we've explored, ad nauseam: the car rental receipts Doggett finds in Mulder's desk plainly communicate four weekend trips in May.
Mulder burns up the first weekend of May on the Squamash trips: he arrives in Pennsylvania on the morning of May the 6th (Saturday) and doesn't leave until the early hours of May the 7th (Sunday.) He is then (allegedly) supposed to drive a 10 hour round trip-- without sleep, while (allegedly) suffering the painful effects of deteriorating "brain disease"-- and be back by Sunday night to prep for an X-Files stakeout on Monday. Both trips cannot coincide with each other, which means one-- or both-- have to go.
Mulder burns up a second weekend on his trip to England: he begins preparing to leave on a Saturday (estimated May 13) and arrives back a day or two later (estimated May 15.)
Mulder might burn up a third weekend recovering from Fight Club: the extent of his injuries would probably inhibit his ability to drive safely-- not to mention the possibility of a compounding, painful "brain disease."
Discounting The Gift (which is rife with inconsistencies and contradictions), two of the four necessary weekends were spent elsewhere.
In fact, the only weekend Doggett can rely on (per his own timeline) is the one following Je Souhaite-- three days before Mulder's abduction. (That weekend will be instrumental later.)
Problem #2: Doggett's "Evidence" Doesn't Match His Timeline
Mulder's VISA card made a lot of purchases over the course of May, some of them reasonable (flowers for his loved ones' graves) and some of them questionable (a headstone and rental cars.)
The VISA card's legitimacy was authenticated by the rental receipts on Mulder's desk-- but those rental dates don't match with Mulder's recorded movements (either by air date or canonical rewrite.) Discounting the Gift, at least two out of four weekends were spent in D.C. or England, not on the road back-and-forth from North Carolina.
Doggett doesn't question this.
That same VISA card was used to explain Mulder's tombstone purchase.
Doggett doesn't question this.
"Mulder" (allegedly) took two trips to Squamash, one the week before his disappearance-- the locals never described what he looked like, only testified that he questioned them and tried to kill the Creature later.
Doggett doesn't question this.
"Mulder" was spotted swiping FBI evidence in order to locate Gibson Praise, and was able to access "his" apartment as well as the office.
Doggett doesn't question this (even after seeing a doppelganger in Without.)
Mulder's VISA card, trips, "brain disease" diagnosis, bloody gun, and falsified report only pop up once he can't challenge their authenticity.
Doggett doesn't question this.
To give the man some credit, most of this can be excused away with the rationale that he doesn't believe in far-reaching conspiracies or boogie men trying to take down Mulder in the dark.
Indisputably, though, the onus is on the writers for tragically mucking up their timeline. Or helpfully, as it's easier to dismiss the entire brain disease arc as a hoax based on these claims.)
Problem #3: The Gift Collapses In On Itself
As previously mentioned, I've combed over The Gift's problems at length (again, post here); but let's go through it once more for totality's sake:
Mulder's trips to Squamash and his trips to his mother's and sister's graves can't coincide, not with late-stage "brain disease."
A solo case, a bloody gun, and falsified signatures-- each piece of "evidence" was missed by Doggett and his team in Within, despite the FBI's fervor to blame Mulder's disappearance on his erratic nature. Each piece of "evidence" conveniently materialized later when Mulder (or Scully) needed to be eliminated from the files.
Scully never confirms or denies the report's authenticity, nor her participation in signing off on it. Conveniently.
In protecting Scully, Skinner and Doggett likely incriminated themselves-- or passed over the clue that would unravel the conspiracy behind the trips, VISA purchases, and "Mulder"'s many appearances.
The last visit by "Mulder" to Squamash is unaccounted for. Say, perhaps, that he had traveled there on May 6 and shot the Creature on May 7-- that doesn't explain why he returned on the 24th. Unless, of course, it wasn't him.
Problem #4: Mulder Would Not Be Physically Capable
Not only would Mulder have to be hiding his (hard-to-miss) brain disease symptoms from Scully-- a medical doctor-- he would have to be squeezing in 10-hour weekend drives routinely after physically-demanding x-files all week.
Problem #5: Scully Was Unaware of Mulder's Weekend Trips
Within posits that Agent Scully was utterly in the dark about her partner's weekend activities-- which is, frankly, ludicrous given her and Mulder's history of constant communication and recent commingling.
This can be explained away with one or two considerations--
Scully was lying to Doggett about not knowing where Mulder was going (North Carolina, i.e. his mother's and sister's graves.)
Scully knew he would disappear every weekend but never bothered to ask where he was going (e.g. spending healthy time apart, caching up on other obligations, etc.)
--but it was not canonically intended. As if that ever stopped the writers or the fans.
Problem #6: Mulder Neither Confirms Nor Denies His Diagnosis
In Deadalive, Scully describes Mulder's condition as, "Blood, electrolyte imbalances, a loss of brain function. I strongly believe that Mulder is infected with an alien virus." (Another one, or the same one?) And when Mulder wakes, she tells him, "Whatever neurological disorder you were suffering from, it's no longer detectable. After a course of transfusions and antivirals it has rid your body of the virus that was invading it. The scars on your face, on your hands, on your feet, on your chest, they, they seem to be repairing themselves. Mulder, you are in perfect health."
Not then nor later does Scully say "your brain disease from last fall is healed"-- in fact, both seem to be discussing the super soldier virus he was infected with on the ship (a sleight of hand for the writers to dodge the ramifications of the brain disease arc.) In fact, is Mulder ever told he, supposedly, had brain disease?
Mulder was taken due to "encephalitic trauma", not brain disease (e.g. none of the other abductees were reported to have had ill health or further, recent complications.)
Mulder was infected with "an alien virus" bound and determined to turn him into a super soldier.
Mulder was returned "deadalive."
Mulder was healed (i.e. taken off of life support.)
So, he was likely told about his "encephalitic trauma" and his close brush with a super soldier zombie "alien" virus... but was Mulder ever specifically told about the (alleged) year-long degenerative brain disease? The one that doesn't kill slowly, and only claimed CSM's life because of the latter man's presumptive co-current comorbidities?
I think not. Whether Mulder did or did not have brain disease, the writers seemed to want to brush that arc briskly under the rug and never acknowledge it ever again-- which is exactly what they did.
BRAIN DISEASE BELIEVERS, THERE IS STILL HOPE
Despite the ravages this meta has wrecked on the brain disease arc, there is still a perfectly reasonable-- and dare I say, logical-- explanation that would seamlessly factor in Mulder's brain disease. One could still indulge in angst alongside Season 7's original intent and Season 8's post-hoc hypothetical with a guilt-free conscience.
May wonders never cease.
Except: the timeline must be drastically shortened.
THREE THEORETICAL TRUTHS
It's all come to this: three possibilities laid out before us.
Each idea works with the same conceit: Mulder was irrefutably (per the loopholes left in the writers' wake) setup by his enemies-- incongruous purchases, trips, and medical records collaboratively pulled together to blacken his name forever in the FBI-- with Scully's reputation soon to follow. The attempts ended with his burial-- which is doubly ironic, considering he rose from the dead three months later-- and the discovery of her pregnancy; but the "proof" of "their" endeavors stuck to the files like smoke.
MULDER WAS RECENTLY DIAGNOSED WITH "BRAIN DISEASE"
According to this theory, Mulder would have to suffer a recent relapse in order to fit in with the "cerebral inflammation" recurrence timescale.
Mulder would've had to suffer another trauma to kick off an autoimmune encephalitic malfunction.
Mulder's relapse couldn't have taken place post-Signs and Wonders or post-Brand X, since Scully would have observed the resulting tremors, mood swings, or early, small-scale seizures.
Fight Club fits the aforementioned criteria and gives Mulder a free weekend to drive to his mother's and sister's graves before Je Souhaite.
Mulder would have to have been given a "to be determined" precaution rather than a full-scale diagnosis because he did not wish to be healed in Je Souhaite.
Mulder would have had to be told bad news post-Je Souhaite and pre-Requiem.
"Cerebral inflammation", as has been hammered home, is not a lengthy death: sustained damage and other comorbid factors are responsible for potentially killing the patient after the disease has been treated. As we also know, "cerebral inflammation" can reoccur via erroneous immune signals or a second traumatic event (which would kick off said erroneous immune signals.)
Mulder was in the hospital three times after Amor Fati: once in Signs and Wonders, once in Brand X, and once in Fight Club. Scully was on hand for the first two concerns, and would have seen the results of his painstaking tests and recovery. But she wouldn't have been able to witness his records in Fight Club (since she was recovering herself.) It is wholly possible that the repeated stresses Mulder's body weathered caused a relapse, one which would have been so new and so recent that it wouldn't have manifested unmistakable symptoms-- yet-- before his abduction in Bellefleur. Given autoimmune encephalitis's grace period, that gives a few weeks to three months before Scully could, theoretically, have figured things out. If that be the case, it also slots onto one of two weekends Mulder had free to travel to North Carolina (Fight Club's case wrapped up on Friday the 19th, a day before Saturday the 20th.)
Most importantly, it saves Mulder's dignity. The greatest injustice of the brain disease arc is that it implies a level of ignorance he fostered on Scully's part-- a proclivity to lie by omission rather than openly share the truth between them. While Mulder does have a history of holding back the complete truth -- his exes and past partners, his retrieval of Scully's ova during the cancer arc, his concerns about Emily's paternity, and his mutual feelings towards her-- he was more vulnerably agape after the consummation of their relationship (displaying his fear quietly in Requiem's "I can't risk losing you" plea.) And let's face it: Mulder isn't equipped for the long con-- Scully unfailingly spots and deduces his schemes or aims.
Combine these factors with Mulder's forgetfulness in Je Souhaite-- not a thought was spared towards his mortality when offered three wishes-- and it makes sense why the medical evaluation and determination interval should be kept short.
By giving Mulder a smaller window of time to process, it falls in line with his and Scully's established character traits: his need to withdraw (e.g. Conduit, Pusher, The Red and the Black, One Son, Amor Fati, etc.) before making and sharing a decision with Scully-- and her innate ability to smell out protracted brooding like a bloodhound.
(And, as formerly mentioned, Mulder never buys a headstone, regardless-- no matter how many falsified VISA cards Doggett finds.)
MULDER DID NOT KNOW HE HAD "BRAIN DISEASE"
This second theory rests on the first's medical possibility, but weaves farther down a different path.
The same chronological order applies-- i.e. autoimmune encephalitis recurrence post-Fight Club.
However, Mulder is unaware of his ailing health: his doctors miss the early symptoms during their examinations; and since Scully is otherwise preoccupied (i.e. recovering), it's never notated.
Since AIEs have an additional buffer period of up to three months, and can be hard to catch without physical symptoms or a thorough MRI, it's plausible that Mulder never knew.
This would also fit with the Bellefleur abductees' "encephalitic trauma", strangely: their old injuries could have been recently triggered-- or forcefully triggered once on the UFO-- in the same manner that Mulder's injury was inflamed post-Fight Club.
This idea plays with the best of both worlds: Mulder's decay looming like a ticking time bomb over his and Scully's happiness; his and Scully's unbroken dedication to the truth and each other. A A VISA card and headstone, grave flowers and falsified reports were setup ahead of time-- orchestrated by the CSM's lingering shadow faction in allegiance with the aliens: Mulder eagerly offered as the price the overlords demanded from the humans.
It also works beautifully with Season 7's intended canon (Mulder whole and hale, with no brain disease in sight) and with his and Scully's miscommunication in Three Words (he assuming she's referring to the super soldier virus, she presuming he knows she knows about his brain disease.)
MULDER DID NOT HAVE "BRAIN DISEASE"
Lastly, Mulder was not dying from brain disease:
Chris Carter and Frank Spotnitz (and the other writers) did not conceptualize Mulder's brain disease when writing Season 7.
Mulder displayed zero symptoms in Season 7 in the weeks and months leading up to its finale.
Mulder did not wish to be healed when he came face-to-face with a genie in Je Souhaite.
The brain disease timeline Agent Doggett digs up in Season 8 is built on manipulable evidence and irrevocably, triumphantly falls apart on itself.
Mulder never confirms nor denies his alleged diagnosis.
According to this theory, Mulder recovered in "Amor Fati" and did not deteriorate further. Instead, he and Scully investigated their subsequent cases with lighter hearts as they finally consolidated their relationship, found his sister, and made peace with their individual and mutual choices in life. When Mulder was hospitalized for venomous snake bites, he did not display any neurological damage. During the events of Closure and En Ami, Scully quickly ascertained that CSM was suffering and dying-- visible, physical symptoms her partner did not have. When Mulder was hospitalized, again, for an infestation of beetles in his lungs, neither his MRIs nor close, personal observation indicated that he had late-stage brain deterioration and neurological or circulatory damage. When Mulder was hospitalized a third time (alongside Scully), whatever (off-screen) complications arose then were not enough to worry him when granted three wishes an episode later.
If this be the case, the evidence "uncovered" in Within and The Gift would have been outright fabricated. This hypothesis aligns in all respects with the flimsy and superbly dissonant pieces canon offers at different times-- information only forthcoming enough to cast doubt on Mulder's and Scully's good name before disappearing immediately afterwards. Evidence, moreover, that is never corroborated between either agent, or between themselves and Agent Doggett.
It would fit with Season 8's timeline, too: perhaps Mulder makes anomalous trips in May-- with or without Scully's knowledge-- but the dates of at least half of those alleged trips clash with weekends he spent on, or preparing for, other investigations. And perhaps Mulder did investigate Squamash (doubtful): his actions there could still be divorced from an ailing, desperate man.
THE TRUE BELIEVERS
Of course, you can always headcanon Mulder did, indeed, have a year-long brain condition; but that would entail a total disregard of the facts. (Then again, when has that stopped canon before?)
FINAL VERDICT
As enlightening, entertaining, or engaging as this project has been, it will probably not shift or shape minds: whether someone believes in the brain disease or not depends on that person's emotional, observational, and intellectual tastes and pursuits.
My only hope is that this work creates or fosters a new perspective.
CONCLUSION
This has been my most researched and re-edited meta to date.
Thank you to @sagan-starstuff for affirming that, no, the brain disease made no sense and that, yes, I hadn't lost my mind. Hopefully the science presented tracks.
Thanks for reading~
Enjoy!
#txf#xf meta#x files#the x files#Mulder#Scully#brain disease#Doggett#In-Depth#S7#S8#mine#meta#Within#The Gift#Amor Fati#Closure#En Ami#xfiles#x-files#Mulder's Brain Disease: an Open-Minded Analytical Dissection#the biggest chonkiest researchiest meta I've done yet#thoughts
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Thinking about how, when I was a kid and the imperial scientific gestalt was still figuring out the human genome, they couldn’t figure out what possible purpose about half of the genome served. It didn’t seem to be involved in metabolism or body plan or really anything expressed phenotypically. They called it “junk DNA” and I stopped hearing about it.
Jump cut a few years into the future, put some grey in my hair to show I’ve aged. I’m reading about the Microbiome. Turns out: our DNA is host to a bunch of Mobile Genetic Elements. If you think Viruses are basic; these guys don’t even bother with a protein shell! Literally simplified down to just bits of DNA, lurking in-between the parts of our genome that are actually us!
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I keep seeing people trying to analyze GQuuuuuuX under the lens of Zeta when they should be analyzing it under the lens of War in the Pocket.
We have a main character who...
-Lives at Side 6
-Lives with just their mother because their father works off colony
-Gets involved with Gundam Nonsense™️ as a means of escaping from the monotony of their artificial life
-Has to deal with Zeon causing problems in their home colony because there's a Gundam hidden in it


There's also the detail of the main Gundams of each show being experimental prototypes made specifically for use by Newtype pilots.

Said Gundams are piloted by redhead girls with red and white pilot suits.


There's definitely a bunch of the other UC shows in its DNA, don't get me wrong (junk dealers with makeshift mobile suits--oh how very ZZ of you), but there's a particular love for War in the Pocket that's just screaming out at me. With that being said, let's hope things go better for Machu than they did for Al...
#mobile suit gundam#gquuuuuux#gquuuuuux spoilers#0080: war in the pocket#war in the pocket#amate yuzuriha#machu#alfred izuruha#christina mackenzie#gundam alex#gundam gquuuuuux#meta#me rambles
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TSRNOSS, p 616.
#mammalian embryology#thymine dimers#excision repair#coldwater fish#ultraviolet absorption by pyrimidines#thymine#nitrous acid#junk DNA#carbon monoxide#solubility#chromium picolinate#iodine#absorption of neutrons by water#evolution of placental mammals#vitamin A#immunity#oligotrophic environment#satyendra sunkavally#cursive handwriting#manuscript
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