#long-acting insulin

[wellhealthhub]

Comprehensive Guide to Diabetes Medications

Welcome to this comprehensive guide on diabetes medications, where we shall explore the intricacies of various pharmacological agents that aid in effectively managing blood sugar levels and fostering a healthier life with diabetes. 1. Insulin Injections Insulin, a paramount hormone synthesized by the pancreas, orchestrates the regulation of blood sugar levels, a critical facet for individuals…

[goldenamaranthe-blog]

All jokes aside about Blake reading smut, Blake definitely has regular books and I can see Yang reading Blake's books to learn how to be romantic to her. Treats Blake like a princess and everything.

Well, there goes four hours of my day.

I can see Yang being an absolute, flustered mess when it comes to being romantic on purpose. Every little romantic tendency she has where she isn't being super cheesy or making a fool of herself is done because she thinks it's just something to help those she loves. Example: learning how to make Blake's favorite tea the way she likes it. SUPER ROMANTIC AND SHE DIDN'T EVEN REALIZE IT!!!

[caitlyn-kirammans]

-

[fooltofancy]

bout to send the most unhinged few days of numbers to my doctor after not talking to him for three months, hope he's excited.

[rose-lily-hale]

diabetes is a lil bitch... i'm dead tired but i have to make myself go stab myself with a needle before i can go to bed .... like wtf

[lxnelyhearrt]

.

[diabeticgirl4]

Hhhh gonna take some long acting insulin w a pen and take what little insulin I have plus shots w me tomorrow and call the pharmacy as soon as they're open, hope everything works out fine wish me luck :):):)

[heathermason1983]

MY FUCKING LANTUS PEN SHATTERED. FUCK MY STUPID GAY BAKA LIFE

[batboyblog]

Things the Biden-Harris Administration Did This Week #31

August 9-16 2024

President Biden and Vice-President Harris announced together the successful conclusion of the first negotiations between Medicare and pharmaceutical companies over drug prices. For years Medicare was not allow to directly negotiate princes with drug companies leaving seniors to pay high prices. It has been a Democratic goal for many years to change this. President Biden noted he first introduced a bill to allow these negotiations as a Senator back in 1973. Thanks to Inflation Reduction Act, passed with no Republican support using Vice-President Harris' tie breaking vote, this long time Democratic goal is now a reality. Savings on these first ten drugs are between 38% and 79% and will collectively save seniors $1.8 billion dollars in out of pocket costs. This comes on top of the Biden-Harris Administration already having capped the price of insulin for Medicare's 3.5 million diabetics at $35 a month, as well as the Administration's plan to cap Medicare out of pocket drug costs at $2,000 a year starting January 2025.

President Biden and Vice President Harris have launched a wide ranging all of government effort to crack down on companies wasting customers time with excessive paperwork, hold times, and robots rather than real people. Some of the actions from the "Time is Money" effort include: The FTC and FCC putting forward rules that require companies to make canceling a subscription or service as easy as signing up for it. The Department of Transportation has required automatic refunds for canceled flights. The CFPB is working on rules to require companies to have to allow customers to speak to a real person with just one button click ending endless "doom loops" of recored messages. The CFPB is also working on rules around chatbots, particularly their use from banks. The FTC is working on rules to ban companies from posting fake reviews, suppressing honest negative reviews, or paying for  positive reviews. HHS and the Department of Labor are taking steps to require insurance companies to allow health claims to be submitted online. All these actions come on top of the Biden Administration's efforts to get rid of junk fees.

President Biden and First Lady Jill Biden announced further funding as part of the President's Cancer Moonshot. The Cancer Moonshot was launched by then Vice-President Biden in 2016 in the aftermath of his son Beau Biden's death from brain cancer in late 2015. It was scrapped by Trump as political retaliation against the Obama-Biden Administration. Revived by President Biden in 2022 it has the goal of cutting the number of cancer deaths in half over the next 25 years, saving 4 million lives. Part of the Moonshot is Advanced Research Projects Agency for Health (ARPA-H), grants to help develop cutting edge technology to prevent, detect, and treat cancer. The President and First Lady announced $150 million in ARPA-H grants this week focused on more successful cancer surgeries. With grants to Tulane, Rice, Johns Hopkins, and Dartmouth, among others, they'll help fund imaging and microscope technology that will allow surgeons to more successfully determine if all cancer has been remove, as well as medical imaging focused on preventing damage to healthy tissues during surgeries.

Vice-President Harris announced a 4-year plan to lower housing costs. The Vice-President plans on offering $25,000 to first time home buyers in down-payment support. It's believed this will help support 1 million first time buyers a year. She also called for the building of 3 million more housing units, and a $40 billion innovation fund to spur innovative housing construction. This adds to President Biden's call for a $10,000 tax credit for first time buyers and calls by the President to punish landlords who raise the rent by over 5%.

President Biden Designates the site of the 1908 Springfield Race Riot a National Monument. The two day riot in Illinois capital took place just blocks away from Abraham Lincoln's Springfield home. In August 1908, 17 people die, including a black infant, and 2,000 black refugees were forced to flee the city. As a direct result of the riot, black community leaders and white allies met a few months later in New York and founded the NAACP. The new National Monument will seek to preserve the history and educate the public both on the horrible race riot as well as the foundation of the NAACP. This is the second time President Biden has used his authority to set up a National Monument protecting black history, after setting up the Emmett Till and Mamie Till-Mobley National Monument on Emmett Till's 82nd birthday July 25th 2023.

The Department of The Interior announced $775 million to help cap and clean up orphaned oil and gas wells. The money will help cap wells in 21 states. The Biden-Harris Administration has allocated $4.7 billion to plug orphaned wells, a billion of which has already been distributed. More than 8,200 such wells have been capped since the Bipartisan Infrastructure Law passed in 2022. Orphaned wells leak toxins into communities and are leaking the super greenhouse gas methane. Plugging them will not only improve the health of nearby communities but help fight climate change on a global level.

Vice-President Harris announced plans to ban price-gouging in the food and grocery industries. This would be a first ever federal ban on price gouging and Harris called for clear "rules of the road" on price rises in food, and strong penalties from the FTC for those who break them. This is in line with President Biden's launching of a federal Strike Force on Unfair and Illegal Pricing in March, and Democratic Senator Bob Casey's bill to ban "shrinkflation". In response to this pressure from Democrats on price gouging and after aggressive questions by Senator Casey and Senator Elizabeth Warren, the supermarket giant Kroger proposed dropping prices by a billion dollars

[ifwerefree]

the adhd diabetic feel when you run home on your lunch break to grab insulin you forgot so you can actually eat your lunch

[jahanmp4]

Things non-French speaking QSMP watchers might not know about q!Etoiles :

• He's very great at behavioural analysis, and will immediately notice if someone is acting oddly

• He's an incredibly patient person, especially when it comes to his friends and Pomme. He may act otherwise but his patience knows no bounds if it means everything turning out for the better. Just look at the q!BBH amnesia arc, he was willing to repeat himself indefinitely as long as it would help q!Bad

• Being aroace, flirting is his love language, as in he could say as much sexual stuff as he wants, for him it will never go as deep as banter, but he knows people do it all the time and he does it for fun/because he knows it will make people laugh and get their attention

• He has a mood compass that goes from incredibly dark and moody to cheerful and light-hearted in the blink of an eye simply when he decides that it's enough brooding for the day. He's great at compartmentalizing his emotions, especially with Pomme around

• He never does something half-heartedly and he actually enjoys building and decorating with Pomme and Richas. He's always suggesting blocks to decorate and is receptive to any of their criticism, and never gets tired of it, he can do it for hours. His love language relies strongly on quality time and acts of service. On every dungeon trip, he will make sure to bring back cute blocks and plants for his daughter, even on the brink of death

• Being a defeatist when it comes to other people is just not in his system. He will always believe that there will be a way to fix any situation and will always see the glass half full, not in a positive way, but rather in a "there will always be a solution available" way. There's not bad or good outcome, only better and worse ones for him

• In every home he ever created with a homey intention, it was always an underground one, nothing is built above it. He's quite the cave dweller and prefers cozy lighting over bright ones. He's a dark, brooding emo who is so fond of colours, he will point it out anytime he sees one he likes (he loves a good jewel tone)

• He is diabetic and has an automatic insulin pump. Not just the streamer, but the cubito as well !

• He cares about his appearance quite a bit, always changing outfits depending on occasions and he's very purposeful about what he puts on and shows on his cubito. He always goes for the cool™ looking stuff and likes to show it off too

EDIT :

• I just remembered this but q!Etoiles has observed that the French speakers trust him MORE when he speaks in French rather than English, especially q!Baghera and q!Aypierre. They are more suspicious when he uses English, and q!Antoine overall doesn't trust him because he trusts NO-ONE aside from Pomme

[wellhealthhub]

Type 2 Diabetes Shots: Managing Your Blood Sugar Levels

The journey of living with the challenging ailment that is type 2 diabetes necessitates unwavering dedication to proper management, thereby engendering the prospect of leading a life that is not merely healthy but replete with fulfillment. Among the fundamental tenets of efficacious type 2 diabetes management is the judicious utilization of insulin or alternative medications in the form of shots,…

[awkward-walking-potato]

since everything went down and the multiverse has been saved, reader and Logan have been living with Wade. Because of that he’s gotten an inside look into their relationship. I think it would be so cute to see reader and Logan’s relationship but from wade’s perspective. Like he’ll (respectfully) watch them as reader has their head on Logan’s thigh as they show him some random funny TikTok and he sort of just rolls his eyes at it. Or Wade comes home to find the both of them passed out on the couch together while a random movie is on in the background. Just things that are really domestic, sweet, and fluffy. I think it would just be really sweet to see their relationship from a different perspective.

Domestic Bliss: A Wade Wilson Retrospective

Wade’s POV

So, I’ve been crashing at Casa de Logan for a while now. You’d think I’d have better things to do than to hang around with a grumpy Canadian mutant and their too-good-for-this-world partner, but let’s be honest—my life’s a circus, and sometimes, you just need to take a break from being the main act. Plus, it’s not like I’m going to get a better view of the Logan and Reader Show anywhere else. Honestly, it’s the most entertaining thing this side of the multiverse, and I’ve seen some Weird stuff.

Take today, for instance. I stroll into the living room, probably covered in blood—I mean, it’s a day ending in ‘y,’ so what else is new?—and there they are: Logan stretched out on the couch like it’s a throne, and Reader draped across his lap like a very happy, very contented blanket.

Reader’s got their phone in hand, showing Logan something that I’m sure is super important. Their head’s on his thigh, which—by the way—is probably the safest place on Earth, considering all the things those thighs have crushed. And Logan? He’s pretending to be all grumpy and uninterested, but I can see the way the corners of his mouth twitch, like he’s just about to smile but doesn’t want to ruin his image.

“Check this out,” Reader says, and their voice has this lilting, sweet tone to it that makes me want to gag in the most respectful way possible. They’re showing him a TikTok, and I catch a glimpse—some stupid cat video, classic Reader—and Logan, good ol’ fashioned Logan, just rolls his eyes. But—and this is the kicker—he watches the whole thing. Doesn’t pull away, doesn’t pretend like he’s not interested. Nope, he’s in it for the long haul, just for them.

I feel my heart do that thing where it’s like, ‘Hey, Wade, remember when you had feelings?’ and I quickly squash it down. Ain’t nobody got time for that.

“Really, Wade?” Logan grumbles, noticing me hovering in the doorway. “Got nothin’ better to do?”

“Not when you two are putting on this much of a show,” I reply, leaning against the doorframe with a smirk. “Seriously, the domestic fluff is off the charts. I’m gonna need insulin if this keeps up.”

Reader snickers, throwing a pillow at me, which I catch because—duh, reflexes. Logan just huffs, but there’s no real heat behind it. If anything, I think he likes that I’m around. I mean, who wouldn’t?

A couple of days later, I get home from one of my little escapades—nothing major, just the usual chaos—and I’m greeted by a sight that nearly makes me drop my katanas. There’s Logan, all six-foot-whatever of him, curled up on the couch with Reader nestled against his chest. They’re both out cold, dead to the world, with some random movie playing in the background. The screen’s showing some cheesy 80s action flick, which, come to think of it, is probably what knocked them out in the first place.

I stand there, just watching for a minute. And I don’t say this often—like, ever—but it’s... nice. There’s something about seeing those two like this, all tangled up together, that makes the world feel a little less messed up. Like, yeah, we’ve been through hell and back saving the multiverse, but at least there’s this. At least there’s them.

I could ruin the moment. I could wake them up, crack a joke, or pull some prank. But I don’t. Instead, I quietly back out of the room, leaving them to their peaceful little bubble.

A few days later, I walk in on them again. This time, they’re in the kitchen. Logan’s making breakfast—pancakes, because apparently, he’s secretly a domestic god—and Reader’s perched on the counter, swinging their legs and chatting about something mundane. Logan’s grumbling about the batter consistency, and Reader’s laughing, this soft, sweet sound that makes Logan’s eyes crinkle at the corners.

“Morning, sunshine!” I announce, because subtlety is for suckers. “Wade,” Logan growls, but it’s the kind of growl that has zero bite. Reader just grins at me, throwing a piece of pancake my way, which I catch in my mouth because I’ve got skills.

“Y’know,” I say, leaning against the fridge, “if I didn’t know better, I’d say you two are disgustingly perfect together. It’s like watching a rom-com, except with more hair and less awkward misunderstandings.”

Logan just rolls his eyes and flips a pancake. “You stickin’ around, or you got places to be?”

“Why, you gonna miss me if I go?” I tease, but honestly? I’m not going anywhere. Not anytime soon.

Logan doesn’t answer, just grunts in that Logan way of his, but I see the way his hand brushes against Reader’s knee as he moves past them, like it’s the most natural thing in the world. And maybe it is, for them.

Maybe that’s the thing about them—about Logan and Reader. They’ve found something here, something that’s real and solid, even after everything we’ve been through. And maybe that’s why I keep sticking around, why I keep watching. Because in a world full of crazy, this right here is something worth staying for.

[im-totally-not-an-alien-2]

Clockwork sees how stressed Danny is from trying to be the goodest boy and never do anything remotely bad that could turn him evil and thinks he may have overdone it. At this rate his panic over never doing anything evil is going to force him to emotionally burn out and stop caring. Then he'll turn evil anyway.

So Clocky does something that sounds completely ridiculous in theory. He scoops Danny up and drops him into a universe full of superheros and villains and tells him to "Do whatever you want. There will be no consequences for you." Then he leaves.

And just like that, Danny goes apeshit. He decides to do the one thing he always wanted to do but was too afraid to because he didn't want to be judged, or worse, forced to join his parents.

He becomes a supervillian. Not as Phantom, no. But as Fenton! He goes full super genius mad scientist and terrorizes whatever city he's in. The local superhero is being driven insane as Danny builds death rays, shrink rays, his own modified version of the GAV, ect.

The best part if that the local heros can never catch him for long and when he is caught he always escapes before he is transported to whatever facility they wanted him in. He always ends up back in his home dimension where he goes back to acting normal and no one from either human dimension or the Infinite Realms knows what he's up to (except the stop watch of course)

After a particularly fun day in which Danny highjacks all broadcasting services to teach everyone in the world how to make insulin at home so you didn't have to pay a ridiculous amount for necessary medication, the Justice League was now on his tail.

Danny just laughs, thinking there's no way they'd ever be able to arrest him. Little does he know some guy calling himself Batman is leading the mission and he has no intention of arresting him. Danny, much to his horror, becomes far to familiar with adoption papers. As in he keeps having to set them on fire.

[fooltofancy]

hate the pens, also, why is a normal syringe less intimidating than this fucking thing

[scientia-rex]

Because my most popular post is about weight loss and how it's a crock, I get a lot of questions about various things, including bariatric surgery--just posted the link to the post I did about that--but also Ozempic/Wegovy, the once-weekly injectable semaglutide medication that was developed for diabetes but was found to have independent benefits on weight loss.

I always said that weight loss was like Viagra: when a medication came along that actually worked, it would explode. We'd all hear about it. Fen-phen in the 90s worked, but it was bad for your heart. Stimulants, like meth, may cause weight loss, but they do it at the cost of heart health, and raise your likelihood of dying young. Over the counter weight loss supplements often contain illegal and unlisted thyroid hormone, which is also dangerous for the heart if taken in the absence of a real deficiency. Orlistat, or "Alli," works the same way as the Olestra chips Lays made in the 1990s--it shuts off your ability to digest fats, and the problem with that is that fats irritate the gut, so then you end up with fatty diarrhea and probably sharts. Plus Alli only leads to 8-10lbs of weight loss in the best case scenario, and most people are not willing to endure sharts for the sake of 8lbs.

And then came the GLP-1 agonists. GLP stands for glucagon-like peptide. Your body uses insulin to make cells uptake sugar. You can't just have free-floating sugar and use it, it has to go into the cells to be used. So if your body sucks at moving sugar into the cells, you end up with a bunch of glucose hanging out in places where it shouldn't be, depositing on small vessels, damaging nerves and your retinas and kidneys and everywhere else that has a whole lot of sensitive small blood vessels, like your brain.

Glucagon makes your liver break down stored sugars and release them. You can think of it as part of insulin's supporting cast. If your body needs sugar and you aren't eating it, you aren't going to die of hypoglycemia, unless you've got some rare genetic conditions--your liver is going to go, whoops, here you go! and cough it up.

But glucagon-like peptide doesn't act quite the same way. What glucagon-like peptide does is actually stimulating your body to release insulin. It inhibits glucagon secretion. It says, we're okay, we're full, we just ate, we don't need more glucagon right now.

This has been enough for many people to both improve blood sugar and cause weight loss. Some patients find they think about food less, which can be a blessing if you have an abnormally active hunger drive, or if you have or had an eating disorder.

However, every patient I've started on semaglutide in any form (Ozempic, Wegovy, or Rybelsus) has had nausea to start with, probably because it slows the rate of stomach emptying. And that nausea sometimes improves, and sometimes it doesn't. There's some reports out now of possible gastroparesis associated with it, which is where the stomach just stops contracting in a way that lets it empty normally into the small intestine. That may not sound like a big deal, but it's a lifelong ticket to abdominal pain and nausea and vomiting, and we are not good at treating it. We're talking Reglan, a sedating anti-nausea but pro-motility agent, which makes many of my patients too sleepy to function, or a gastric pacemaker, which is a relatively new surgery. You can also try a macrolide antibiotic, like erythromycin, but I have had almost no success in getting insurance to cover those and also they have their own significant side effects.

Rapid weight loss from any cause, whether illness, medication, or surgery, comes with problems. Your skin is not able to contract quickly. It probably will, over long periods of time, but "Ozempic face" and "Ozempic butt" are not what people who want to lose weight are looking for. Your vision of your ideal body does not include loose, excess skin.

The data are also pretty clear that you can't "kick start" weight loss with Ozempic and then maintain it with behavioral mechanisms. If you want to maintain the weight loss, you need to stay on the medication. A dose that is high enough to cause weight loss is significantly higher than the minimum dose where we see improvements in blood sugar, and with a higher dose comes higher risk of side effects.

I would wait on semaglutide. I would wait because it's been out for a couple of years now but with the current explosion in popularity we're going to see more nuanced data on side effects emerging. When you go from Phase III human trials to actual use in the world, you get thousands or millions more data points, and rare side effects that weren't seen in the small human trials become apparent. It's why I always say my favorite things for a drug to be are old, safe, and cheap.

I also suspect the oral form, Rybelsus, is going to get more popular and be refined in some way. It's currently prohibitively expensive--all of these are; we're talking 1200 or so bucks a month before insurance, and insurance coverage varies widely. I have patients who pay anything from zero to thirty to three hundred bucks a month for injectable semaglutide. I don't think I currently have anyone whose insurance covers Rybelsus who could also tolerate the nausea. My panel right now is about a thousand patients.

There are also other GLP-1 agonists. Victoza, a twice-daily injection, and Trulicity, and anything else that ends in "-aglutide". But those aren't as popular, despite being cheaper, and they aren't specifically approved for weight loss.

Mounjaro is a newer one, tirzepatide, that acts on two receptors rather than one. In addition to stimulating GLP-1 receptors, it also stimulates glucose-dependent insulinotropic polypeptide (GIP) receptors. It may work better; I'm not sure whether that's going to come with a concomitantly increased risk of side effects. It's still only approved for diabetes treatment, but I suspect that will change soon and I suspect we'll see a lot of cross-over in terms of using it to treat obesity.

I don't think these medications are going away. I also don't think they're right for everyone. They can reactivate medullary thyroid carcinoma; they can fuck up digestion; they may lead to decreased quality of life. So while there may be people who do well with them, it is okay if those people are not you. You do not owe being thin to anyone. You most certainly do not owe being thin to the extent that you should risk your health for it. Being thin makes navigating a deeply fat-hating world easier, in many ways, so I never blame anyone for wanting to be thin; I just want to emphasize that it is okay if you stay fat forever.