#it better be in the script

[mysterygrl20]

domundi better give me a ZeeNunew extravagant royal wedding in the next prince

[reasonsforhope]

"Tim Friede’s YouTube channel is home to a collection of videos depicting the Wisconsin-native truck mechanic subjecting himself to purposeful snake bites, blood slowly dripping down his arms.

For the past 20 years, Friede has been one of the most notorious “unconventional” medical researchers, undergoing over 200 bites from the world’s deadliest snakes — and more than four times as many — 850 — venomous injections. 

He did it all in the name of science.

According to the World Health Organization, an estimated 100,000 people are killed by snake bites each year, with countless more being disabled by the venom of the deadly reptiles. 

While life-saving anti-venom is available, very few countries actually have the capacity to produce it properly, given that most bites occur in remote and rural areas, and anti-venom requires arduous sourcing and accuracy. 

But Friede’s blood is now full of antibodies, following decades of strategic exposure to the neurotoxins of mambas, cobras, and other lethal slithering critters.

His blood is now the source material researchers are using to develop an anti-venom capable of neutralizing a broad spectrum of snake bites...

Friede started this hobby — which he is indeed adamant no one else tries at home — out of sheer curiosity in childhood. After playing with harmless garter snakes in his youth, he began keeping more dangerous species of snakes as pets. At one point, he had 60 of them in his home basement.

In 1999, he began extracting venom from his snakes, drying it, diluting it, and injecting himself with tiny doses — keeping meticulous records as he went.

He had one major hospitalization in 2001, when he was paralyzed and in a coma for four days. But instead of giving up, he doubled down. 

“In hindsight, I’m glad it happened,” Friede told The Times. “I never made another mistake.”

Jacob Glanville, an immunologist and founder of biotech company Centivax, stumbled on Friede’s videos.

Now, Friede is the director of herpetology at Centivax and serves as something of a “human lab” to Glanville.

“For a period of nearly 18 years, [Tim] had undertaken hundreds of bites and self-immunizations with escalating doses from 16 species of very lethal snakes that would normally a kill a horse,” Glanville told The Guardian.

“It blew my mind. I contacted him because I thought if anyone in the world has these properly neutralizing antibodies, it’s him.”

To develop the new anti-venom, Glanville and his fellow researchers identified 19 of the world’s deadliest snakes — in the elapid family — which kill their prey by injecting neurotoxins into their bloodstream, paralyzing muscles (including the big, important ones, like the heart and lungs).

The trouble is, each species in the elapid family has a slightly different toxin, meaning they would each require their own anti-venom.

But Friede’s blood contains certain fragments of each of these toxins; protein molecules seen across the various species. Because of his decades of service to science, his blood also contains the antibodies required to neutralize these toxins, preventing them from sticking to human cells and causing harm.

Combining the antibodies LNX-D09, SNX-B03, and a small molecule called varespladib that inhibits venom toxins, Centivax has successfully created a treatment effective against the entire range of 19 species’ toxins.

Their work, which was recently published in the journal Cell, will soon be tested outside of the lab. 

Trials will start with using the serum to treat dogs admitted to Australian veterinary clinics for snake bites. Assuming that goes well, the next step will be to administer human tests.

Researchers also believe that because the serum stems from a human, this should also lower the risk of allergic reactions when being administered to other people. 

“The final product would be a single, pan-anti-venom cocktail,” Professor Peter Kwong of Columbia University, a senior author of the study, told The Times.

Or, he added, they could make two: “One that is for the elapids, and another that is for the viperids, because some areas of the world only have one or the other.”

As for Friede, he maintains his affinity for snakes, though his last bite was in November 2018, when he said “enough is enough,” according to The New York Times.

By then, he had certainly done enough. His pursuit of immunity could feasibly save countless lives.

“I’m really proud that I can do something in life for humanity,” Friede told The New York Times, “to make a difference for people that are 8,000 miles away, that I’m never going to meet, never going to talk to, never going to see, probably.”

-via GoodGoodGood, May 2, 2025

[blackkatdraws2]

[Blank Scripts | TSP] Some old art I had lying around

[tobercat]

so i heard dino stamatopoulos is currently writing a script for a moral orel movie

guys im insane

[strawlessandbraless]

Jensen Ackles saw this early script draft and made the choice that Dean would NOT make Cas feel bad for hugging him after the angel thought him dead

In fact, he let Dean be fully embraced by Cas, let him melt into the hug with a soft smile. Dean got to proudly Introduce his angel to Mary without shame or embarrassment, and that’s beautiful

[xiofaire]

somewhere out there a permashifter needs to hear this.

[beefcakekinard]

what he says: like that? so that was okay? so what're you doing saturday? i guess it's just me that makes you nervous. you're adorable. okay. of course. i'll try my damnedest to make it to the wedding. sorry i'm late. you okay? god, i hope so. has anyone ever told you you're a vision in a cone? i came as soon as my shift ended. got you a fresh ice pack and ibuprofen. i'll be right over here if you need anything. i got you some coffee and some avocado toast. that's not what i said. stop picking. oh, that's not true. please lift it. i'm going to guess it's our six month anniversary. we've got time. if i were to move in with you, you wouldn't mean to, you wouldn't plan for it, but you'd end up breaking my heart, and i don't think that i could deal with that. i've been fighting the urge to call you for months. i was driving by your place the other day. not without feeding you. why not? what are you doing on saturday? and for you.

what he means: i love you.

[gothamite-rambler]

Red Robin and Signal were on a stakeout mission with Arsenal (Roy Harper). The night was slow, so Duke and Tim started chatting about anime. Duke was a huge fan and made it clear that slander against anime would not be tolerated.

Signal and Red Robin had been discussing Fullmetal Alchemist for the past twenty minutes after an hour of tedious surveillance, watching a building from a distance and waiting for the signal to strike.

Arsenal sat on the ground with his bow resting on his lap, contemplating whether he should have informed the sitter about Lian wanting a glass of water before bed.

Signal: I'm telling you, Edward should’ve killed that man. What he did to his daughter and dog was messed up. The man did this twice, mind you. Edward should’ve shoved that medal down his throat. Why did Scar get the kill?

Red Robin: Because Elric knew it would be wrong.

Signal (incensed): He turned his daughter into a Chimera! He did the same to his wife! None of them deserved that, but the father deserved to choke on that medal!

Red Robin (shrugging): That doesn’t mean he can react with murder. Elric knew he would regret it.

Signal (dismissive): See, if that was me—without the Signal persona—I would've done it!

As the two heroes continued to debate, Arsenal interrupted.

Arsenal: Edward killing the man would've felt like a hollow victory. He would’ve struggled even more with giving his chimera daughter a mercy killing. Scar showed regret too, but I believe he knew it had to be done. Plus, I like Scar, so I might be a little biased, but I stand by it.

Signal and Red Robin went silent, staring at Arsenal, surprised by the archer's take.

Signal (whispering): He watches anime?

Arsenal (overhearing them): I did a lot as a kid. Then, when I was a year into recovery, I rewatched Sailor Moon and went from there.

Signal: Subs or dubs?

Arsenal: Subtitles, since I know Japanese. Dubs if I'm multitasking.

Signal: That’s a good answer. Alright, shounen vs. seinen?

Arsenal (texting on his phone): Shounen. It’s cliché, but Dragon Ball still holds up. Except for the movie. That doesn’t count as a good movie, though.

Signal: Exactly!

Signal smacked Red Robin on the arm, repeating the word.

Red Robin: I said I didn’t hate the movie as much as you; that doesn’t mean I liked it.

Signal (suspicious): Mm-hm. Oh, I got one that’s Dragon Ball-related. Vegeta in the Buu saga—

Arsenal: The only one who knew what he was doing. Gohan constantly pissed me off.

Signal: My ninja! That’s what I’m talking about!

Signal high-fived Arsenal while the archer was busy texting the sitter for an update on whether his daughter was in bed.

Signal: I like him. He’s cool with me. Unlike you, saying One Piece is peak anime and that Boruto is good.

Arsenal (offended): Oh God!

Batman (shouting through all the communication devices): FOCUS!

Red Robin: If you just treat it like it’s its own thing—

Signal: We will talk about this later.

[fawnontheweb]

“ Who’s the main character in your DR? “

[sunderwight]

I absolutely get where people are coming from with Dom Mobei Jun in fics and it's often extremely good, but there is just so so much potential with Dom Shang Qinghua and Sub Mobei Jun.

I just really think they would be into the switch in their public-facing relationship dynamics for bedroom activities. The games they could play! Clever "lowly" servant Shang Qinghua pretending he's blackmailing or tricking Mobei Jun into servicing him for revenge, gloating about how he's got his king just where he wants him, getting to really cut loose on the degradation dirty talk (venting for all those years of holding back any kind of criticism out of fear for his life) while Mobei Jun gets some traditional demon courtship fixes out of the process, and also enjoys the opportunity to just completely turn off his brain and his vigilance around someone who he 100% trusts not to abuse the privilege.

Heck, their relationship didn't actually gain ground on physical intimacy until Shang Qinghua started finally cracking and losing his temper and demanding Mobei Jun respect him (and... call him 'daddy', of course...), and when Mobei Jun finally gets Shang Qinghua to tell him how to court him he's like "finally" and makes him the world's worst noodles about it. He's glad that Shang Qinghua is telling him what to do in order to please him! He wants that.

In conclusion, Mobei Jun would absolutely enjoy being bossed around and I think Shang Qinghua would equally enjoy ordering him to do various bedroom activities, in the most unrefined terms available, and being immediately served & obeyed.

[jackabbot]

⚡️ 9-1-1 • S3E15 || S6E10 ⚡️

[lucabyte]

Not all who wander are lost. Some who wander, however, are extremely, extremely lost.

[time-woods]

formal company event ! yes im pullin out all the romcom tropes for this series

[bunnieswithknives]

OH MY GOD??? HAS IT SERIOUSLY BEEN A MONTH????? I am so sorry guys

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[rosebudshifter]

do you have any tips for scripting a better cr?

things to script for your better cr

N O W L O A D I N G.... your better cr

-‘๑’- there is no hate or prejudice whatsoever -‘๑’- there is no global warming because we actually take care of the earth -‘๑’- your hair is easy to style and doesn't get dirty/greasy often -‘๑’- when shopping/thrifting, you find the best hidden gems. everything fits you perfectly. -‘๑’- it never rains when you have an important event (unless of course it adds to the dramatics) -‘๑’- no matter where you are, if you look up at the stars you can see the milky way -‘๑’- good grades, always (obvi) -‘๑’- if you're ever called on in class randomly, you always have the right answer -‘๑’- school is always interesting -‘๑’- there is never a dull day in your life -- either big things like celebrations, or small things like an adorable little bunny sat next to you in the park -‘๑’- never a bad hair or makeup day -‘๑’- you have the perfect outfit for every occasion -‘๑’- your shoes never leave blisters on your feet and are always comfortable -‘๑’- jewelry never turns your skin green -‘๑’- you have the perfect playlist for every occasion. anytime you're with your friends they beg you to take the AUX. -‘๑’- you move through life with an almost otherworldly type of grace. you never misstep, and you never misspeak. -‘๑’- you and your friend group get up to all kinds of hijinks. one moment you're having a movie night, the next you've somehow found yourself in a crop circle. -‘๑’- in whatever town/city you live in, there are plenty of locations to go and hang out with your friends -‘๑’- you can't get sunburnt (cuz who wants to deal with that?) -‘๑’- your nails always look good, even if they're bare -‘๑’- you have an amazing sense of style -‘๑’- you're photogenic from any angle -‘๑’- you have a great sense of direction. even if you're traveling to someplace new, you always manage to find your way -- all while discovering little hidden areas along the way. -‘๑’- you are always the most interesting person in the room. when you walk in, you can feel the metaphorical (or physical, if the occasion calls for it) spotlight focus on you.

[poorly-drawn-mdzs]

Thanks for listening to my sad backstory. Anyway, here's Wonderwall.

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