#post script

[3liza]

this is less of a complaint and more of an educational lecture: when you write "PS" to leave a little addendum to the end of a note, that's short for "post script", eg, "after the text". postscripts became customary in the days of handwriting and then typewriters because it was really hard to go back up into a finished letter and insert more text before computers, so if you had any additional thoughts or corrections, you had to add them at the bottom.

ok i told you that so i can tell you this: when you have a second post script, the acronym is PPS, not PSS. PPS stands for post-post-script. post-script-script doesn't really make any sense in this context. you can just keep adding Ps to make each additional thought even more post, if you want. and plenty of antique letter writers with ADHD certainly did.

[theheightofdishonor]

thinking about Udai and how post-timeskip he seems settled where he is in terms of life and volleyball and the distinctly monstrous glint in his eye when he learns that he's awakened new little giants and inspired players that he might never even know and that he's had an impact and just -when is a monster not a monster? false question a monster is always a monster even when its asleep

[to-eat-a-grape]

P.S. - I mean it.

[reasonsforhope]

"Tim Friede’s YouTube channel is home to a collection of videos depicting the Wisconsin-native truck mechanic subjecting himself to purposeful snake bites, blood slowly dripping down his arms.

For the past 20 years, Friede has been one of the most notorious “unconventional” medical researchers, undergoing over 200 bites from the world’s deadliest snakes — and more than four times as many — 850 — venomous injections. 

He did it all in the name of science.

According to the World Health Organization, an estimated 100,000 people are killed by snake bites each year, with countless more being disabled by the venom of the deadly reptiles. 

While life-saving anti-venom is available, very few countries actually have the capacity to produce it properly, given that most bites occur in remote and rural areas, and anti-venom requires arduous sourcing and accuracy. 

But Friede’s blood is now full of antibodies, following decades of strategic exposure to the neurotoxins of mambas, cobras, and other lethal slithering critters.

His blood is now the source material researchers are using to develop an anti-venom capable of neutralizing a broad spectrum of snake bites...

Friede started this hobby — which he is indeed adamant no one else tries at home — out of sheer curiosity in childhood. After playing with harmless garter snakes in his youth, he began keeping more dangerous species of snakes as pets. At one point, he had 60 of them in his home basement.

In 1999, he began extracting venom from his snakes, drying it, diluting it, and injecting himself with tiny doses — keeping meticulous records as he went.

He had one major hospitalization in 2001, when he was paralyzed and in a coma for four days. But instead of giving up, he doubled down. 

“In hindsight, I’m glad it happened,” Friede told The Times. “I never made another mistake.”

Jacob Glanville, an immunologist and founder of biotech company Centivax, stumbled on Friede’s videos.

Now, Friede is the director of herpetology at Centivax and serves as something of a “human lab” to Glanville.

“For a period of nearly 18 years, [Tim] had undertaken hundreds of bites and self-immunizations with escalating doses from 16 species of very lethal snakes that would normally a kill a horse,” Glanville told The Guardian.

“It blew my mind. I contacted him because I thought if anyone in the world has these properly neutralizing antibodies, it’s him.”

To develop the new anti-venom, Glanville and his fellow researchers identified 19 of the world’s deadliest snakes — in the elapid family — which kill their prey by injecting neurotoxins into their bloodstream, paralyzing muscles (including the big, important ones, like the heart and lungs).

The trouble is, each species in the elapid family has a slightly different toxin, meaning they would each require their own anti-venom.

But Friede’s blood contains certain fragments of each of these toxins; protein molecules seen across the various species. Because of his decades of service to science, his blood also contains the antibodies required to neutralize these toxins, preventing them from sticking to human cells and causing harm.

Combining the antibodies LNX-D09, SNX-B03, and a small molecule called varespladib that inhibits venom toxins, Centivax has successfully created a treatment effective against the entire range of 19 species’ toxins.

Their work, which was recently published in the journal Cell, will soon be tested outside of the lab. 

Trials will start with using the serum to treat dogs admitted to Australian veterinary clinics for snake bites. Assuming that goes well, the next step will be to administer human tests.

Researchers also believe that because the serum stems from a human, this should also lower the risk of allergic reactions when being administered to other people. 

“The final product would be a single, pan-anti-venom cocktail,” Professor Peter Kwong of Columbia University, a senior author of the study, told The Times.

Or, he added, they could make two: “One that is for the elapids, and another that is for the viperids, because some areas of the world only have one or the other.”

As for Friede, he maintains his affinity for snakes, though his last bite was in November 2018, when he said “enough is enough,” according to The New York Times.

By then, he had certainly done enough. His pursuit of immunity could feasibly save countless lives.

“I’m really proud that I can do something in life for humanity,” Friede told The New York Times, “to make a difference for people that are 8,000 miles away, that I’m never going to meet, never going to talk to, never going to see, probably.”

-via GoodGoodGood, May 2, 2025

[himeshifts]

reminder: shifting is real. you’re going to have memories from when you were a kid or random interactions with people you knew back then. even the dream you may have had when you were 10... oh and perhaps the supermarket you visited with your parents 6 years ago? your life in your dr doesn’t start from the moment you shift there. life is still life. don’t treat your dr as a ‘magical‘ place.

[egelskop]

[fanaticalthings]

the muskification of twitter except it's lex luthor instead of elon lol

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[majunju]

instinct [1/?]

[deancasforcutie]

nothing I'm just sighing dreamily kicking my feet thinking about how Dean is loving to Cas <333

bonus:

[amaretto-mp4]

Also finally wrote a short-ish lore post on the two OCs I frequently share about on here (at least in these past few months); gonna queue that next!

Figured I should at least give little bit of bg info before the next barrage y’know

[kaioumichiru]

Phoebe bridgers unplucked eyebrows sexy!!!!

[leofwines]

[4eversleep1ng]

CONVERSATION THINGS TO SCRIPT

💭 for the awkward people (me) 💭

You always know how to add yourselves into conversations naturally.

People actually listen and value what you say.

You don’t get anxious around new people and won’t stammer.

No one cuts you off when you are speaking.

You will never accidentally cross boundaries.

You always know what to say and how to fill awkward silences.

You can keep up with conversations that change all the time.

Everyone around you genuinely really likes talking to you and know they can trust you with whatever they have going on.

The people you talk to are always aware if you’re being sarcastic and never take anything to heart.

You know how to put your thoughts and emotions into words.

(^) You are good with your words. (Flirting, comforting, etc)

A/N: Feels like I said ‘You’ too many times..sorry for that. Posts pretty short…so at least you don’t have to add much into your script? 🤗

[that-edgy-gal]

Yoooooo I just got officially brought I to the union and I've already got my first contract secured

[isjasz]

Happy late Valentines ft. an alternative version to the end of Total Eclipse @zipzapzooooooom wrote during comic production <3

[carolinanadeau]

"this female character is underdeveloped" TO YOU. I can read subtext and I know all about her backstory and her rich inner life. also she told me personally