#post script:

[reasonsforhope]

"Tim Friede’s YouTube channel is home to a collection of videos depicting the Wisconsin-native truck mechanic subjecting himself to purposeful snake bites, blood slowly dripping down his arms.

For the past 20 years, Friede has been one of the most notorious “unconventional” medical researchers, undergoing over 200 bites from the world’s deadliest snakes — and more than four times as many — 850 — venomous injections. 

He did it all in the name of science.

According to the World Health Organization, an estimated 100,000 people are killed by snake bites each year, with countless more being disabled by the venom of the deadly reptiles. 

While life-saving anti-venom is available, very few countries actually have the capacity to produce it properly, given that most bites occur in remote and rural areas, and anti-venom requires arduous sourcing and accuracy. 

But Friede’s blood is now full of antibodies, following decades of strategic exposure to the neurotoxins of mambas, cobras, and other lethal slithering critters.

His blood is now the source material researchers are using to develop an anti-venom capable of neutralizing a broad spectrum of snake bites...

Friede started this hobby — which he is indeed adamant no one else tries at home — out of sheer curiosity in childhood. After playing with harmless garter snakes in his youth, he began keeping more dangerous species of snakes as pets. At one point, he had 60 of them in his home basement.

In 1999, he began extracting venom from his snakes, drying it, diluting it, and injecting himself with tiny doses — keeping meticulous records as he went.

He had one major hospitalization in 2001, when he was paralyzed and in a coma for four days. But instead of giving up, he doubled down. 

“In hindsight, I’m glad it happened,” Friede told The Times. “I never made another mistake.”

Jacob Glanville, an immunologist and founder of biotech company Centivax, stumbled on Friede’s videos.

Now, Friede is the director of herpetology at Centivax and serves as something of a “human lab” to Glanville.

“For a period of nearly 18 years, [Tim] had undertaken hundreds of bites and self-immunizations with escalating doses from 16 species of very lethal snakes that would normally a kill a horse,” Glanville told The Guardian.

“It blew my mind. I contacted him because I thought if anyone in the world has these properly neutralizing antibodies, it’s him.”

To develop the new anti-venom, Glanville and his fellow researchers identified 19 of the world’s deadliest snakes — in the elapid family — which kill their prey by injecting neurotoxins into their bloodstream, paralyzing muscles (including the big, important ones, like the heart and lungs).

The trouble is, each species in the elapid family has a slightly different toxin, meaning they would each require their own anti-venom.

But Friede’s blood contains certain fragments of each of these toxins; protein molecules seen across the various species. Because of his decades of service to science, his blood also contains the antibodies required to neutralize these toxins, preventing them from sticking to human cells and causing harm.

Combining the antibodies LNX-D09, SNX-B03, and a small molecule called varespladib that inhibits venom toxins, Centivax has successfully created a treatment effective against the entire range of 19 species’ toxins.

Their work, which was recently published in the journal Cell, will soon be tested outside of the lab. 

Trials will start with using the serum to treat dogs admitted to Australian veterinary clinics for snake bites. Assuming that goes well, the next step will be to administer human tests.

Researchers also believe that because the serum stems from a human, this should also lower the risk of allergic reactions when being administered to other people. 

“The final product would be a single, pan-anti-venom cocktail,” Professor Peter Kwong of Columbia University, a senior author of the study, told The Times.

Or, he added, they could make two: “One that is for the elapids, and another that is for the viperids, because some areas of the world only have one or the other.”

As for Friede, he maintains his affinity for snakes, though his last bite was in November 2018, when he said “enough is enough,” according to The New York Times.

By then, he had certainly done enough. His pursuit of immunity could feasibly save countless lives.

“I’m really proud that I can do something in life for humanity,” Friede told The New York Times, “to make a difference for people that are 8,000 miles away, that I’m never going to meet, never going to talk to, never going to see, probably.”

-via GoodGoodGood, May 2, 2025

[himeshifts]

reminder: shifting is real. you’re going to have memories from when you were a kid or random interactions with people you knew back then. even the dream you may have had when you were 10... oh and perhaps the supermarket you visited with your parents 6 years ago? your life in your dr doesn’t start from the moment you shift there. life is still life. don’t treat your dr as a ‘magical‘ place.

[deancasforcutie]

nothing I'm just sighing dreamily kicking my feet thinking about how Dean is loving to Cas <333

bonus:

[egelskop]

[akanemnon]

Will other-script Kris and frisk have different designs from twin runes? It just came to me that that was a possibility.

YES! I've showed them off before actually! You can find them if you seach for "the other script" or "lost in the in-between" tag!

Buuuuuuut here's also something I made a while back but never showed off

This is what I'm going with for Kris and Frisk. But the whole cast will have different designs from Twin Runes thanks to the nature of The Other Script being a lot darker in parts and not shying away from directly showing that. The impact would be lost if the designs were still the same as in Twin Runes. (Also it would make it difficult to differenciate the two)

[4eversleep1ng]

CONVERSATION THINGS TO SCRIPT

💭 for the awkward people (me) 💭

You always know how to add yourselves into conversations naturally.

People actually listen and value what you say.

You don’t get anxious around new people and won’t stammer.

No one cuts you off when you are speaking.

You will never accidentally cross boundaries.

You always know what to say and how to fill awkward silences.

You can keep up with conversations that change all the time.

Everyone around you genuinely really likes talking to you and know they can trust you with whatever they have going on.

The people you talk to are always aware if you’re being sarcastic and never take anything to heart.

You know how to put your thoughts and emotions into words.

(^) You are good with your words. (Flirting, comforting, etc)

A/N: Feels like I said ‘You’ too many times..sorry for that. Posts pretty short…so at least you don’t have to add much into your script? 🤗

[fanaticalthings]

the muskification of twitter except it's lex luthor instead of elon lol

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[majunju]

instinct [1/?]

[leofwines]

[isjasz]

Happy late Valentines ft. an alternative version to the end of Total Eclipse @zipzapzooooooom wrote during comic production <3

[tainkirrahe]

so Ruby Sunday was likely meant to be Desiderium before behind the scenes stuff made the show go to all hell.

This is an expansion of the theory I posted on Bluesky (kicked off by this Reddit thread), and maybe I am just copin' and seethin' but. like. even Charles Dickens would think this is all too much of a coincidence to not be Something.

Here's how I think it probably went down before Millie and Ncuti decided to leave early: The Rani kidnaps the God of Wishes and places her with a normal foster family, moving in next door to keep tabs on her, and when the time comes engineers things for the Doctor to take an interest in her (Church on Ruby Road). Ruby's DNA scans as human because she was born to human parents, but cannot be traced in the UK because she was born 180 years ago in Bavaria. And also her mum is flowers.

In Space Babies Fifteen wishes he and Ruby could be Poppy's parents within earshot of the God of Wishes, who unintentionally makes this true when Wish World opens with Ruby and John Smith having Poppy as their kid. Series 1 then plays out much as it had done before, with Ruby's ability to recognise something is wrong with the Doctorless universe in 73 Yards and Maestro's fear of her hidden song because she's a powerful member of the Pantheon. I think the rewrites only began with the ending of Empire of Death - in the original cut, it turns out even the fash DNA supercomputer doesn't know who she is and we're left on a cliffhanger with regards to this.

Ruby decides to take time out of the TARDIS after seeing the whole universe end and whilst Fifteen is off having adventures in Joy to the World she briefly dates Alan Budd before dumping him due to his controlling behaviour during a date where he gifts her a star certificate. She rejoins Fifteen after she is kidnapped by robots from Missrubysunday (with Ruby replacing Belinda this season the star certificate thing is centred on her) and he rescues her, with the time fracture in that episode reversing the events of the episode but leaving Alan's memory intact. He's dumped back on Earth where he becomes determined to ruin Ruby's life and so Lucky Day is about Alan, not Conrad, attacking UNIT/Ruby. At the end of the episode Alan is picked up by an ecstatic Rani who now has the God of Wishes and her ex boyfriend who has a serious grudge against her and wants to change the world for the worst.

Season two remains pretty much the same as well. We then hit the finale which also plays out the same initially - sorry guys I think Omega was always going to be a skeleton baby :( - but with Ruby ending the fake reality by breaking into where Alan is holding her as a baby and touching her baby self's hand, just like the resolution with the certificate in Robot Revolution. The universe resets but Ruby notices Poppy is missing, able to remember her because a) she was the one who cast the wish; b) her experience with parallel universes (73 Yards); and c) her characterisation as an "abandoned" baby who wants everyone to have a home. She uses her powers one final time to bring Poppy back and decides to leave the TARDIS for good and raise her new daughter.

The episode ends with Ruby donning the Rani's cloak and leaving her baby self outside the church on Ruby Road to ensure the timeloop is maintained, changing Fifteen's memory by pointing at the Doctor just as we saw in Empire in order to keep that mystery intact as well.

Fifteen, touched by Ruby's decision, flies off in the TARDIS determined to find Susan. and also rescue Rogue from Superb Hell I guess #justiceforrogue

The end.

(To be clear I adore Belinda, the above was not written to write her out of the show - I think she deserved better in her own story, when clearly she was simply recycled from story beats taken from Ruby).

Some supporting evidence -

• Desiderium is the seventh child of a seventh child. Ruby Sunday's name alludes to both: rubies are the birthstone of July, the seventh month, and Sunday is the seventh day of the week.

• the Goblins in Church on Ruby Road fed on coincidences. Desiderium was born to the Zufall family. Zufall in German means "coincidence".

• The Rani talks about having to keep track of the Doctor's companions to make her plan to summon Omega work, but only actually references Ruby by making a slight about blonde girls. Belinda also has absolutely no impact on The Rani's plan whatsoever, to the extent she was locked in a box for the whole finale, so The Rani's interest in her feels utterly pointless. (Because it was).

• Strong themes of motherhood, childhood abandonment, and adoption paralleling what happened with the Doctor as per Timeless Child revelations throughout the series that make absolutely no sense for Belinda, who came from a home with both parents present. Ruby was always meant to complement Fifteen's recent discovery of his adopted status and help him work through it as he helped her work through hers.

• Space Babies also literally opens the show on a spaceship misinterpreting stories and making them real.

• The odd duplication of fashy boys Conrad and Alan - it makes more narrative sense if they were both once the same character who got sawed in half during hasty rewrites.

• Ruby's name being tied to sevens is similar to River Song, Melody Pond, and Amy Pond being related to water, hinting at their connection.

maybe I am wrong, maybe the show was always meant to be written this way but like. theorising. is also fun!

[arayapendragon]

manifestation can be however you like

you don't need to affirm, persist, visualize, live in the end, robotically affirm, or write down affirmations in a journal to confirm your desire is already yours. neither do you need to detach, let go, or enter the sabbath state.

you can do whatever you want to manifest your desires, and the same goes for shifting. you don't need a method or any special technique. if you're doing something that feels right, that feels enough, then stick to it. you don't need to step out of your comfort zone or put in effort to get what you want. manifestation is effortless and supposed to be fun. don't force yourself to do something you aren't enjoying.

i just manifested a vape out of the blue, even though the environment in my 3d was such that i would most likely not get one. i didn't detach, i didn't do anything extra. in fact, i was obsessed with my desire (nic cravings are NOT fun guys..). i was doubting, i was wavering. i was starting to think i wouldn't get it at all. still, i manifested to the best of my ability. listened to subliminals, acted like i already had it (just a few times) and felt the joy and relief of a nic buzz before actually having one. that's literally all i did. i was so obsessed and couldn't "detach" or "let go" like i normally do, and i still got it. this goes to show that there's no ideal mindset, no ideal state, no ideal technique for shifting and manifesting. you can literally do anything, or do nothing, and still get your desire. as long as you do what you like without taking the fun away from the process, i assure you that you'll get your desire. there's no one way to manifest or shift. i literally just shifted to this parallel cr where i have my desire in under an hour. i decided, and so i received. if i can do it, so can you my friend ;)

[carolinanadeau]

"this female character is underdeveloped" TO YOU. I can read subtext and I know all about her backstory and her rich inner life. also she told me personally

[reallyunluckyrunaway]

[swift-shift]

a little reminder that shiftblr is NOT a safe place for TERFS. you're a transphobe, you're an asshole, you are not welcome here. trans women are women and trans women who are shifters are welcome in this space. you, on the other hand, are not. please find somewhere else to exist. or better yet, don't exist at all.

happy pride to my trans girl shifters out there. you're safe with me.

[dailyralsei]

the healer [ 8 / 11 ]

[ p. 7 p. 6 full comic ]